Faculty

Institution

Unit

Venue

Janelle C. Arthur

Associate Professor

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Microbiology and Immunology

Janelle C. Arthur is currently serving as a Microbiology And Immunology Associate Professor at University of North Carolina At Chapel Hill.

Honors

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Experiences

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Education

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Janelle C. Arthur

University of North Carolina at Chapel Hill

Associate Professor

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immunology microbiology clinical microbiology gastroenterology inflammatory bowel disease inflammation colorectal cancer microbiome microbial pathogenesis gut microbes digestive diseases public health mucosal immunology veterinary medicine oncology cancer biology veterinary microbiology microbial ecology medical microbiology cell biology environmental microbiology molecular gastroenterology dysbiosis probiotics applied microbiology infection control molecular microbiology cell regulation microbial physiology gut barrier adaptive immune system chronic inflammation ulcerative colitis innate immune system host-microbe interactions inflammatory diseases molecular cancer medical mycology cancer care animal nutrition genome biology oral microbiology gastrointestinal oncology microbial diversity gut microbiota dendritic cells intestinal microbial composition mouse model cell death cancer cells free radical biology redox biology microbial hazards molecular immunology immune dysregulation immune mediators clinical mycology cancer treatment molecular regulation enhanced recovery high throughput sequencing protein evolution evolutionary microbiology microbial risk assessment escherichia coli cancer inflammation negative regulation noncanonical nf-kb signaling bacteria-induced colorectal cancer microbial genomic analysis myeloid cell migration contact hypersensitivity colon cancer immunotherapy resistance conjugated linoleic acid probiotic bacteria gut-organ axis pathology microbiota interactions

Notable Scholarly Works

Notable Federal Grants

Collaborators

121 Mucus Digested by Ruminococcus Gnavus Preferentially Enhances Growth of Crohn's Disease-Associated Adherentinvasive E. Coli (Aiec) via Bacterial Cross-Feeding. Gastroenterology (2024)

Saori KashiwagiBelgin DoganShiying ZhangSwetha PeddibhotlaMousumi PaulchakrabartiSebastian Perez-OrozcoSimon GrayElizabeth BoazakBill ThelinJanelle C. ArthurSebastian E. WinterBiswa ChoudhuryKenneth W. SimpsonR. Balfour Sartor

digestive diseasesmicrobiologyinfectious diseasesinflammatory bowel diseasemicrobiomegastroenterologymucosal immunologymolecular gastroenterologydigestive tractvia bacterial cross-feedinggut microbesulcerative colitis

729 Saccharomyces Boulardii Reduces Colitis-Associated Colorectal Cancer Burden in a Mouse Model of Inflammatory Bowel Disease. Gastroenterology (2024)

Tyler CulpepperMairead K. HeaveyAnthony HazeltonJuliane NguyenJanelle C. Arthur

mouse modelhealth sciencescolorectal cancerinflammatory bowel diseasegastroenterology

A Consortia of Clinical E. Coli Strains With Distinct In-Vitro Adherent/Invasive Properties Establish Their Own Co-Colonization Niche and Shape the Intestinal Microbiota in Inflammation-Susceptible Mice. Gastroenterology (2024)

Chuang LiRachel BleichShan SunJu-Hyun AhnBelgin DoganCassandra BarlogioChristopher BrobergEmily Bulik-SullivanIan CarrollKenneth SimpsonAnthony FodorJanelle Arthur

pathogenic bacteriapathogensinfection controlmicrobiologymicrobial pathogenesisinfectious diseaseshost-microbe interactionsmicrobiomedysbiosismucosal immunologygut microbesimmunologyclinical microbiology

Chuang LiRachel BleichShan SunJu-Hyun AhnBelgin DoganCassandra BarlogioChristopher BrobergEmily Bulik-SullivanIan CarrollKenneth SimpsonAnthony FodorJanelle Arthur

pathogenic bacteriapathogensinflammation-susceptible micemicrobiologymicrobial pathogenesisinfectious diseasesinflammationinflammatory bowel diseaseimmunologyintestinal microbiotamicrobial diseaseclinical microbiology

Intestinal E. Coli-Produced Yersiniabactin Promotes Profibrotic Macrophages in Crohn’s Disease. Cell Host & Microbe (2024)

Ju-Hyun AhnMarlus da Silva PedrosaLacey R LopezTaylor N TibbsJoanna N JeyachandranEmily E VignieriAaron RothemichIan CummingAlexander D IrmscherCorey J HaswellWilliam C ZamboniYen-Rei A YuMelissa EllermannLee A DensonJanelle C Arthur

pathogensmicrobiologymicrobial pathogenesisinflammationinfectious diseaseshost-microbe interactionshost responseprofibrotic macrophages

Targeted Delivery of the Probiotic Saccharomyces Boulardii to the Extracellular Matrix Enhances Gut Residence Time and Recovery in Murine Colitis. Nature Communications (2024)

Mairead K. HeaveyAnthony HazeltonYuyan WangMitzy GarnerAaron C. AnselmoJanelle C. ArthurJuliane Nguyen

digestive diseasesgastroenterologymurine colitisdrug deliveryimmunologybiotechnologyextracellular matrixcell biologytargeted deliverybiomedical engineeringregenerative medicineenhanced recovery

Zinc Restriction by Intestinal E. Coli - Produced Yersiniabactin Activates Hif-1α in Macrophages to Promote CD-Associated Fibrosis. Gastroenterology (2024)

Ju-Hyun AhnLacey LopezTaylor TibbsYen-Rei YuRobert TigheLee DensonJanelle Arthur

geneticshepatologydigestive diseasesmicrobiologygene expressioninflammationcd-associated fibrosisgastroenterologyinnate immune systemmolecular gastroenterologydisease physiologypathway analysisimmunologyfibrosiszinc restrictionhematologyclinical gastroenterologyclinical microbiology

Zinc Restriction by Intestinal E. Coli - Produced Yersiniabactin Activates Hif-1 α in Macrophages to Promote CD-Associated Fibrosis. Inflammatory Bowel Diseases (2024)

Ju-Hyun AhnLacey LopezTaylor TibbsYen-Rei YuRobert TigheLee DensonJanelle Arthur

pathogenic bacteriapathogensmicrobiologymicrobial pathogenesisinflammationinfectious diseasesinflammatory bowel diseasechronic inflammationimmunologyfibrosismicrobial diseaseinflammatory diseasescd-associated fibrosis

Heterogeneity Among Clinical Intestinal Escherichia Coli Isolates Upon Acquired Streptomycin Resistance. Microbiology Spectrum (2023)

Lacey R. LopezClaire M. MillerJoanna N. JeyachandranChuang LiKenneth W. SimpsonJanelle C. Arthur

pathogenic bacteriaantimicrobial agentsdigestive diseasesacquired streptomycin resistancemicrobiologyinfectious diseasesclinical microbiologydrug resistancestreptomycin resistanceinflammatory bowel diseaseantimicrobial resistanceantibiotic resistanceantimicrobial resistance genesgut microbesescherichia coli isolatesantimicrobial susceptibilityantibiotics

Killing Tumor-Associated Bacteria With a Liposomal Antibiotic Generates Neoantigens That Induce Anti-Tumor Immune Responses. Nature Biotechnology (2023)

Menglin WangBenoit RousseauKunyu QiuGuannan HuangYu ZhangHang SuChristine Le Bihan-BenjaminInes KhatiOliver ArtzMichael B FooteYung-Yi ChengKuo-Hsiung LeeMichael Z MiaoYue SunPhilippe-Jean BousquetMarc HilmiElise DumasAnne-Sophie HamyFabien ReyalLin LinPaul M ArmisteadWantong SongAva VargasonJanelle C ArthurYun LiuJianfeng GuoXuefei ZhouJuliane NguyenYongqun HeJenny P-Y TingAaron C AnselmoLeaf Huang

pharmacologycancer immunotherapycancer biologymedical mycologymicrobiologycancer treatmentoncologyclinical mycologyimmunologybiotechnologyanti-tumor immune responsescancer caretumor-associated bacteriaclinical microbiology

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Janelle C. Arthur

Associate Professor

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Microbiology and Immunology

Janelle C. Arthur is currently serving as a Microbiology And Immunology Associate Professor at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Janelle C. Arthur

University of North Carolina at Chapel Hill

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

121 Mucus Digested by Ruminococcus Gnavus Preferentially Enhances Growth of Crohn's Disease-Associated Adherentinvasive E. Coli (Aiec) via Bacterial Cross-Feeding. Gastroenterology (2024)

729 Saccharomyces Boulardii Reduces Colitis-Associated Colorectal Cancer Burden in a Mouse Model of Inflammatory Bowel Disease. Gastroenterology (2024)

Tyler CulpepperMairead K. HeaveyAnthony HazeltonJuliane NguyenJanelle C. Arthur

mouse modelhealth sciencescolorectal cancerinflammatory bowel diseasegastroenterology

Chuang LiRachel BleichShan SunJu-Hyun AhnBelgin DoganCassandra BarlogioChristopher BrobergEmily Bulik-SullivanIan CarrollKenneth SimpsonAnthony FodorJanelle Arthur

Intestinal E. Coli-Produced Yersiniabactin Promotes Profibrotic Macrophages in Crohn’s Disease. Cell Host & Microbe (2024)

pathogensmicrobiologymicrobial pathogenesisinflammationinfectious diseaseshost-microbe interactionshost responseprofibrotic macrophages

Targeted Delivery of the Probiotic Saccharomyces Boulardii to the Extracellular Matrix Enhances Gut Residence Time and Recovery in Murine Colitis. Nature Communications (2024)

Mairead K. HeaveyAnthony HazeltonYuyan WangMitzy GarnerAaron C. AnselmoJanelle C. ArthurJuliane Nguyen

digestive diseasesgastroenterologymurine colitisdrug deliveryimmunologybiotechnologyextracellular matrixcell biologytargeted deliverybiomedical engineeringregenerative medicineenhanced recovery

Zinc Restriction by Intestinal E. Coli - Produced Yersiniabactin Activates Hif-1α in Macrophages to Promote CD-Associated Fibrosis. Gastroenterology (2024)

Ju-Hyun AhnLacey LopezTaylor TibbsYen-Rei YuRobert TigheLee DensonJanelle Arthur

Zinc Restriction by Intestinal E. Coli - Produced Yersiniabactin Activates Hif-1 α in Macrophages to Promote CD-Associated Fibrosis. Inflammatory Bowel Diseases (2024)

Ju-Hyun AhnLacey LopezTaylor TibbsYen-Rei YuRobert TigheLee DensonJanelle Arthur

Heterogeneity Among Clinical Intestinal Escherichia Coli Isolates Upon Acquired Streptomycin Resistance. Microbiology Spectrum (2023)

Lacey R. LopezClaire M. MillerJoanna N. JeyachandranChuang LiKenneth W. SimpsonJanelle C. Arthur

Killing Tumor-Associated Bacteria With a Liposomal Antibiotic Generates Neoantigens That Induce Anti-Tumor Immune Responses. Nature Biotechnology (2023)

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