Faculty

Institution

Unit

Venue

Jamie Alan

Associate Professor

Michigan State University

Affiliations

College of Human Medicine

Department of Pharmacology and Toxicology

College of Natural Science

Jamie Alan is currently serving as a College Of Human Medicine Associate Professor at Michigan State University.

Honors

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Experiences

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Education

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Jamie Alan

Michigan State University

Associate Professor

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molecular biology genetics cell biology neuroscience oncology cancer biology cell signaling cancer research signal transduction membrane biology gene expression medicinal research enzyme inhibition cancer genetics cell regulation caenorhabditis elegans molecular and cellular biology enzymes mammalian biology pharmacotherapy avian biology animal nutrition clinical pharmacology rho gtpases polyunsaturated fatty acids rho gtpase function molecular cell biology redox biology protein science gynecologic oncology genome biology cancer care molecular cancer pharmacological research cancer cells biological chemistry cancer genomics cellular biology biomolecular interactions gene characterization cell interactions functional modification redox signaling molecular regulation transcription regulation functional regulation colorectal cancer tumor targeting signaling pathways cancer prevention oncogenic agent cancer treatment cancer growth melanoma skin cancer protein function later adulthood nutrient physiology pharmaceutical care pharmaceutical sciences pharmaceutical research pharmaceutical education liquid chromatography intracellular trafficking epithelial morphogenesis functional characterization mammalian cells c-terminal tyrosine phosphorylation ovarian carcinoma growth multiple cytoskeletal pathways neurosteroid modulation axon guidance lung cancer cells diclofenac enhances acid-induced apoptosis cancer phenotypes aging process aging cell brain health longevity neuroscience of aging neuro-oncology ageing molecular neurodegeneration experimental gerontology biogerontology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 2176 the Molecular Crosstalk Between Cytochrome P450-Epoxide Hydrolase Metabolism of Polyunsaturated Fatty Acid and Neurodegeneration. Journal of Biological Chemistry (2024)

Kin Sing Stephen LeeMorteza SarparastJennifer HinmanSachini Kodippili PatabendigeElham PourmandDerek VonarxJamie Alan

polyunsaturated fatty acidmolecular biologybiological chemistrymolecular crosstalkbiochemistry

Cytochrome P450 and Epoxide Hydrolase Metabolites in Aβ and Tau-Induced Neurodegeneration: Insights From Caenorhabditis Elegans. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Morteza SarparastJennifer HinmanElham PourmandDerek VonarxLeslie RamirezWenjuan MaNicole F. LiachkoJamie K. AlanKin Sing Stephen Lee

pharmacologyepoxide hydrolase metabolitesmetabolismcaenorhabditis elegansneuroscience

Dihydroxy-Metabolites of Dihomo-γ-Linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration. ACS Central Science (2023)

Morteza SarparastElham PourmandJennifer HinmanDerek VonarxTommy ReasonFan ZhangShreya PaithankarBin ChenBabak BorhanJennifer L. WattsJamie AlanKin Sing Stephen Lee

neuroscience

Pi3K Functions Downstream of Cdc42 to Drive Cancer Phenotypes in a Melanoma Cell Line. Small GTPases (2023)

Rosemary PokuFelix AmissahJamie K. Alan

dermatologygene expressionmelanomaprotein functioncancer geneticscancer researchgeneticsmammalian biologyoncologymedicinal researchcancer phenotypescancer biologyskin cancertumor biologymelanoma cell linecell biology

Pufas and Nsaids Inhibit Lung Cancer Metastatic Process Through Rho Gtpase Signaling. American Journal of Pharmaceutical Education (2023)

Lauren E. PerryHailey M. YorkRosemary A. PokuFELIX AMISSAHJamie Alan

rho gtpaseclinical pharmacologypharmaceutical sciencestranslational medicinemedicinepharmaceutical researchpharmaceutical carehealth sciencespharmaceutical educationcancer researchlung cancerpharmacologythoracic oncologypharmacotherapydrug discoveryoncologyrespiratory medicinemedicinal researchpharmaceutics

Quantitative Profiling Method for Oxylipins in Neurodegenerative Diseases by Liquid Chromatography Coupled With Tandem Mass Spectrometry. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Elham PourmandFan ZhangMorteza SarparastJamie K. AlanKin Sing Stephen Lee

neurologypharmacologyliquid chromatographyquantitative profiling methodanalytical chemistrytandem mass spectrometryneuroscience

An Endogenous Polyunsaturated Fatty Acid, Dihomo‐Gamma‐Linoleic Acid, Induces Neurodegeneration in C. Elegans via Ferroptosis. The FASEB Journal (2022)

Kin Sing Stephen LeeMorteza SarparastFan ZhangPourmand SeyedehelhamRoland E. GonzalezBenjamin KesslerBenjamin HeasmanJamie Alan

dihomo-gamma-linoleic acidneuroscience

Metabolism of Dietary Polyunsaturated Fatty Acids Modulates Healthspan of C. Elegans. The FASEB Journal (2021)

Kin Sing Stephen LeeJamie AlanMorteza SarparastzardroudiFan ZhangSeyedehelham PourmandBenjamin KesslerDevon Dattmore

physiologymetabolismanimal nutrition

Suppressing Lung Cancer Cell Migration and Invasion Through Disruption of Rho Gtpase Function by Diclofenac and Docosahexaenoic Acid. The FASEB Journal (2021)

Megan Van BarenJoshua MatsonRosemary PokuJamie AlanFelix Amissah

immunologyin vitro toxicologyenzyme inhibitioncancer biologythoracic oncologycancer researchrho gtpase functiondocosahexaenoic acidmolecular biologyoncologymedicinal researchlung cancertumor biologymolecular medicinecell biology

Using C. Elegans to Investigate the Effects of Polyunsaturated Fatty Acids and Their Metabolites on Lifespan and Healthspan. The FASEB Journal (2021)

Benjamin KesslerMorteza SarparastFan ZhangDevon DattmoreJamie AlanKin Sing Stephen Lee

physiologyavian biologygeneticspolyunsaturated fatty acidsmorphological impactmolecular biologymetabolism

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Jamie Alan

Associate Professor

Michigan State University

Affiliations

College of Human Medicine

Department of Pharmacology and Toxicology

College of Natural Science

Jamie Alan is currently serving as a College Of Human Medicine Associate Professor at Michigan State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jamie Alan

Michigan State University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 2176 the Molecular Crosstalk Between Cytochrome P450-Epoxide Hydrolase Metabolism of Polyunsaturated Fatty Acid and Neurodegeneration. Journal of Biological Chemistry (2024)

Kin Sing Stephen LeeMorteza SarparastJennifer HinmanSachini Kodippili PatabendigeElham PourmandDerek VonarxJamie Alan

polyunsaturated fatty acidmolecular biologybiological chemistrymolecular crosstalkbiochemistry

Cytochrome P450 and Epoxide Hydrolase Metabolites in Aβ and Tau-Induced Neurodegeneration: Insights From Caenorhabditis Elegans. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Morteza SarparastJennifer HinmanElham PourmandDerek VonarxLeslie RamirezWenjuan MaNicole F. LiachkoJamie K. AlanKin Sing Stephen Lee

pharmacologyepoxide hydrolase metabolitesmetabolismcaenorhabditis elegansneuroscience

Dihydroxy-Metabolites of Dihomo-γ-Linolenic Acid Drive Ferroptosis-Mediated Neurodegeneration. ACS Central Science (2023)

Morteza SarparastElham PourmandJennifer HinmanDerek VonarxTommy ReasonFan ZhangShreya PaithankarBin ChenBabak BorhanJennifer L. WattsJamie AlanKin Sing Stephen Lee

neuroscience

Pi3K Functions Downstream of Cdc42 to Drive Cancer Phenotypes in a Melanoma Cell Line. Small GTPases (2023)

Rosemary PokuFelix AmissahJamie K. Alan

Pufas and Nsaids Inhibit Lung Cancer Metastatic Process Through Rho Gtpase Signaling. American Journal of Pharmaceutical Education (2023)

Lauren E. PerryHailey M. YorkRosemary A. PokuFELIX AMISSAHJamie Alan

Quantitative Profiling Method for Oxylipins in Neurodegenerative Diseases by Liquid Chromatography Coupled With Tandem Mass Spectrometry. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Elham PourmandFan ZhangMorteza SarparastJamie K. AlanKin Sing Stephen Lee

neurologypharmacologyliquid chromatographyquantitative profiling methodanalytical chemistrytandem mass spectrometryneuroscience

An Endogenous Polyunsaturated Fatty Acid, Dihomo‐Gamma‐Linoleic Acid, Induces Neurodegeneration in C. Elegans via Ferroptosis. The FASEB Journal (2022)

Kin Sing Stephen LeeMorteza SarparastFan ZhangPourmand SeyedehelhamRoland E. GonzalezBenjamin KesslerBenjamin HeasmanJamie Alan

dihomo-gamma-linoleic acidneuroscience

Metabolism of Dietary Polyunsaturated Fatty Acids Modulates Healthspan of C. Elegans. The FASEB Journal (2021)

Kin Sing Stephen LeeJamie AlanMorteza SarparastzardroudiFan ZhangSeyedehelham PourmandBenjamin KesslerDevon Dattmore

physiologymetabolismanimal nutrition

Suppressing Lung Cancer Cell Migration and Invasion Through Disruption of Rho Gtpase Function by Diclofenac and Docosahexaenoic Acid. The FASEB Journal (2021)

Megan Van BarenJoshua MatsonRosemary PokuJamie AlanFelix Amissah

Using C. Elegans to Investigate the Effects of Polyunsaturated Fatty Acids and Their Metabolites on Lifespan and Healthspan. The FASEB Journal (2021)

Benjamin KesslerMorteza SarparastFan ZhangDevon DattmoreJamie AlanKin Sing Stephen Lee

physiologyavian biologygeneticspolyunsaturated fatty acidsmorphological impactmolecular biologymetabolism

1
2
3
10 / page

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Institution

Drexel University

cellular senescence

endocrinology

Matthew Hirschey

Institution

Duke University

physiology

molecular biology

Michal Masternak

Institution

University of Central Florida

longevity

growth hormone

Steven Clarke

Institution

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biochemistry

molecular biology

Alan Dombkowski

Institution

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tuberous sclerosis complex

exosomes

David B. Lombard

Institution

University of Miami

epigenetics

cell biology

Pinchas Cohen

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pharmacology

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Institution

University of Virginia

ophthalmology

cell biology

Meghan McGee-Lawrence

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osteoporosis

skeletal homeostasis

Gino Cortopassi

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pharmacological research

translational pharmacology