Faculty

Institution

Unit

Venue

James West

Professor of Medicine

Vanderbilt University

Affiliations

Graduate School

Biochemistry

School of Engineering

Biomedical Engineering

James West is currently serving as a Biochemistry Professor of Medicine at Vanderbilt University.

Honors

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Experiences

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Education

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James West

Vanderbilt University

Professor of Medicine

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respiratory medicine pharmacology cardiology physiology health sciences pulmonary arterial hypertension vascular biology genetics membrane biology liver physiology gene expression pulmonary circulation inflammation hematology cardiovascular research molecular physiology mammalian biology circulatory physiology cellular physiology pulmonary hypertension cardiovascular disease endocrinology medicinal research cardiovascular physiology redox biology animal physiology toxicology medical genetics angiogenesis free radical biology treatment and prevention protein science clinical physiology mammalian physiology angiology cell regulation cell death signaling pathways hemostasis experimental medicine in vivo systems respiratory neurobiology respiration (physiology) apoptosis molecular regulation bone morphogenic protein vascular adaptation pulmonary fibrosis clinical investigation gene function mesenchymal stem cells human physiology cell physiology cancer biology cancer genomics cancer genetics cardiomyopathy host response thromboxane-prostanoid receptor lipid disorders veterinary research pathway analysis gene regulation smooth muscle transgenic mice mouse models endothelial-to-mesenchymal transition endogenous generation reactive oxidants heat shock metabolic defects right ventricular lipotoxicity lipid accumulation diethyl acetylenedicarboxylate right ventricular hypertrophy rodent model pulmonary vascular disease hypertension critical care idiopathic pulmonary hypertension

Notable Scholarly Works

Notable Federal Grants

Collaborators

Single-Cell Rnaseq Reveals Transcriptional Changes in Venous Endothelial Cells That Suggest a Post-Capillary Mechanism of Ild-Associated Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine (2025)

pulmonary vascular diseasesingle-cell analysisgene expressionrespiratory medicinecardiovascular researchild-associated pulmonary hypertensionpost-capillary mechanismpulmonary arterial hypertensionblood vesselsimmunologyvascular biologycirculatory physiologycell biologypulmonary circulationinterstitial lung diseaseendothelial dysfunctionvenous endothelial cells

Activation of Mtor Signaling in Adult Lung Microvascular Progenitor Cells Accelerates Lung Aging and Defines a Capillary Progenitor Niche. (2024)

E.P. LundbergE.C. MasonS. MenonM.M. DawsonC.M. MooreB.W. RichmondJ.A. KropskiJ.D. WestP.M. GeraghtyB.N. GompertsF.S. GallyS.M. Majka

liver physiologycellular physiologycell regulationcell biologyregenerative medicinestem cellsmembrane biologyvascular adaptationcapillary progenitor nichevascular biologyosmoregulationpharmacologygene expressioninflammationstem cell researchmicrovascular dysfunctionangiogenesisexperimental gerontologyhealth sciences

A Multimodal Approach Identifies Lactate as a Central Feature of Right Ventricular Failure That is Detectable in Human Plasma. Frontiers in Medicine (2024)

Anna HemnesNiki FortuneKatie SimonIrina A TrenarySheila ShayEric AustinJamey D YoungEvan BritainJames WestMegha Talati

clinical medicinehuman plasmamedicineright ventricular failure

Ces1 Deficiency is Associated With Endothelial Dysfunction and Metabolic Reprograming in Pah. (2024)

S. AgarwalL. HeoA. ChakrabortyJ.D. WestK. SureshR.V. NairM.R. NicollsC. MorisseauB.D. HammockR.A. LafyatisS.M. KawutR.T. ZamanianV. De Jesus Perez

metabolic reprogramingneurosciencevascular biologyhematologyendothelial dysfunctionphysiology

Neutrophil Elastase Drives Emphysema and Airway Wall Remodeling, but Not Goblet Cell Metaplasia, in a Mouse Copd Model. (2024)

S.S. GutorI.P. GaonaW. HanR.P. HuntD.S. NicholsB.W. RichmondJ.D. WestV.V. PolosukhinT.S. Blackwell

pharmacologyrespiratory medicinemouse copd modelstrokeneuroscienceimmunologyvascular biologyprotein science

Redox Regulation of Proteostasis. Journal of Biological Chemistry (2024)

Long Duy DuongJames D WestKevin A Morano

biochemistryoxidative stressredox chemistryproteomicscell metabolismreductive stressreceptorsredox regulationbiological chemistryredox signalingredox biologyfree radical biologysecondary metabolismchemical biologyredox regulatorantioxidantsmolecular biologysystems biologycell signaling

Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome. AJP Lung Cellular and Molecular Physiology (2024)

Sergey S. GutorRodrigo I. SalinasDavid S. NicholsJulia M. R. BazzanoWei HanJason J. GokeyGeorgii VasiukovJames D. WestDawn C. NewcombAnna E. DikalovaBradley W. RichmondSergey I. DikalovTimothy S. BlackwellVasiliy V. Polosukhin

animal physiologyrespiratory medicinemolecular physiologyrespiration (physiology)human biologymammalian biologyphysiology

2-Hoba Resolves Metabolic Problems in Two Pulmonary Hypertension Models. (2023)

J.D. WestC. MooreE.J. CarrierS. GladsonS. ShayA. Hemnes

pulmonary hypertension modelsmetabolismrespiratory medicinehealth sciences

Abstract 14483: Myeloid Cell Derived Il1B Contributes to Pulmonary Vascular Remodeling in Heart Failure With Preserved Ejection Fraction. Circulation (2023)

Vineet AgrawalJon KropskiJason J GokeyElizabeth KobeckMatthew MurphyKatherine T MurrayNiki FortuneChristy MooreDavid MeoliKen MonahanYan Ru SuThomas BlackwellDeepak K GuptaMegha TalatiSanthi GladsonErica J CarrierJames WestAnna R Hemnes

cardiovascular physiologypreserved ejection fractionvascular adaptationrespiratory medicinemyeloid cellcardiovascular researchcardiologycirculatory physiologyimmunologyvascular biologycell biologyheart failurehematologyphysiology

Abstract 17218: Ces1 Deficiency is Associated With Metabolic Reprograming and Endothelial Dysfunction in Pulmonary Arterial Hypertension. Circulation (2023)

Stuti AgarwalLyong HeoAnanya ChakrabortyNatasha AuerGowri SwaminathanLichao LiuJames WestKarthik SureshRamesh NairMarlene RabinovitchMark NicollsChristophe MorisseauBruce D HammockRobert LafyatisSteven M KawutRoham ZamanianVinicio A Dejesus

health sciencescardiologymetabolic reprogramingpulmonary arterial hypertensionvascular biologyendothelial dysfunctionphysiology

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James West

Professor of Medicine

Vanderbilt University

Affiliations

Graduate School

Biochemistry

School of Engineering

Biomedical Engineering

James West is currently serving as a Biochemistry Professor of Medicine at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James West

Vanderbilt University

Professor of Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Activation of Mtor Signaling in Adult Lung Microvascular Progenitor Cells Accelerates Lung Aging and Defines a Capillary Progenitor Niche. (2024)

E.P. LundbergE.C. MasonS. MenonM.M. DawsonC.M. MooreB.W. RichmondJ.A. KropskiJ.D. WestP.M. GeraghtyB.N. GompertsF.S. GallyS.M. Majka

A Multimodal Approach Identifies Lactate as a Central Feature of Right Ventricular Failure That is Detectable in Human Plasma. Frontiers in Medicine (2024)

Anna HemnesNiki FortuneKatie SimonIrina A TrenarySheila ShayEric AustinJamey D YoungEvan BritainJames WestMegha Talati

clinical medicinehuman plasmamedicineright ventricular failure

Ces1 Deficiency is Associated With Endothelial Dysfunction and Metabolic Reprograming in Pah. (2024)

S. AgarwalL. HeoA. ChakrabortyJ.D. WestK. SureshR.V. NairM.R. NicollsC. MorisseauB.D. HammockR.A. LafyatisS.M. KawutR.T. ZamanianV. De Jesus Perez

metabolic reprogramingneurosciencevascular biologyhematologyendothelial dysfunctionphysiology

Neutrophil Elastase Drives Emphysema and Airway Wall Remodeling, but Not Goblet Cell Metaplasia, in a Mouse Copd Model. (2024)

S.S. GutorI.P. GaonaW. HanR.P. HuntD.S. NicholsB.W. RichmondJ.D. WestV.V. PolosukhinT.S. Blackwell

pharmacologyrespiratory medicinemouse copd modelstrokeneuroscienceimmunologyvascular biologyprotein science

Redox Regulation of Proteostasis. Journal of Biological Chemistry (2024)

Long Duy DuongJames D WestKevin A Morano

Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome. AJP Lung Cellular and Molecular Physiology (2024)

animal physiologyrespiratory medicinemolecular physiologyrespiration (physiology)human biologymammalian biologyphysiology

2-Hoba Resolves Metabolic Problems in Two Pulmonary Hypertension Models. (2023)

J.D. WestC. MooreE.J. CarrierS. GladsonS. ShayA. Hemnes

pulmonary hypertension modelsmetabolismrespiratory medicinehealth sciences

Abstract 14483: Myeloid Cell Derived Il1B Contributes to Pulmonary Vascular Remodeling in Heart Failure With Preserved Ejection Fraction. Circulation (2023)

Abstract 17218: Ces1 Deficiency is Associated With Metabolic Reprograming and Endothelial Dysfunction in Pulmonary Arterial Hypertension. Circulation (2023)

health sciencescardiologymetabolic reprogramingpulmonary arterial hypertensionvascular biologyendothelial dysfunctionphysiology

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5
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10 / page

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