Faculty

Institution

Unit

Venue

James W. Simpkins

Professor

West Virginia University

Affiliations

School of Medicine

Neuroscience

James W. Simpkins is currently serving as a Neuroscience Professor at West Virginia University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James W. Simpkins

West Virginia University

Professor

You can click a keyword to filter the displayed items

neuroscience neurology pharmacology endocrinology physiology neuropharmacology neuroprotection mammalian biology stroke brain science alzheimer's disease neurochemistry medicinal research cerebrovascular disease neurophysiology animal physiology experimental medicine endocrine research oxidative stress psychoneuroendocrinology receptors central nervous system vascular biology pharmacological research neuroradiology avian biology neuroinflammation mitochondrial function redox biology experimental gerontology respiratory medicine pharmacotherapy clinical neuroscience experimental pharmacology behavioral neuroendocrinology cellular neurobiology mammalian physiology neuroprotective effects female rats pharmaceutical research liver physiology treatment effects steroid metabolism pharmaceutical sciences male rats ethanol withdrawal pharmacokinetics biogerontology brain function cerebral blood flow antioxidants geriatric endocrinology neural science clinical pharmacology experimental biology ischemic stroke dopamine human physiology treatment and prevention molecular neurobiology microrna detection veterinary physiology estrogen neuroprotection female rat traumatic brain injury brain imaging comparative endocrinology hormonal receptor ethanol-withdrawn rats hormone secretion cerebral ischemia transient cerebral ischemia estrogen protection menopausal hot flush ovariectomized rats female sprague-dawley rats beta amyloid neuroscience of aging molecular neurodegeneration aging cell vascular cognitive disorder neurochemical biomarkers medicine

Notable Scholarly Works

Notable Federal Grants

Collaborators

Brain-Wide Transgene Expression in Mice by Systemic Injection of Genetically Engineered Exosomes: Cap-Exosomes. Pharmaceuticals (2024)

Saumyendra N. SarkarDeborah CorbinJames W. Simpkins

genetic engineeringbrain-wide transgene expressionpharmaceutical sciencesneurosciencepharmacologymedicinesystemic injectionpharmaceutical research

Chronic Stress Mediates Cerebral Blood Flow Alterations via Xanthine Oxidase in an Early-Onset Alzheimer's Disease Model. Free Radical Biology and Medicine (2024)

Saina PrabhuNicole EminhizerAlec HanshewSteven BallEric KelleyPaul ChantlerJames Simpkins

alzheimer's diseasechronic stressdisease modelstress (biology)neurodegenerative diseasescerebral blood flowxanthine oxidaseearly-onset alzheimermedicinefree radical biology

Prospective Study of Extracellular Vesicles in Plasma as Potential Biomarkers for Silent Brain Infarcts (P10-4.013). Neurology (2024)

Lincey WilsonDuaa DakhlallahAnna ZukowskiJacob RalstonKate KarelinaJames SimpkinsMuhammad AlviCandace Brown

neurologyprospective studysilent brain infarctsbiomarkerscerebrovascular diseaseextracellular vesicles

Abstract Wp211: Mir-34A Modulates Outcomes After Experimental Stroke in Mice. Stroke (2023)

Xuefang RenSaumyendra SarkarMax EvansJames SimpkinsLena O'KeefeAaron GusdonRyan KitagawaHuimahn ChoiHeng Hu

neurologyexperimental strokemicrorna detectionneurosciencestroke

Acute Exposure to Artificial Light at Night Alters Hippocampal Vascular Structure in Mice. iScience (2023)

Jacob R. BumgarnerWilliam H. WalkerDominic D. QuintanaRhett C. WhiteAlexandra A. RichmondO. Hecmarie Meléndez-FernándezJennifer A. LiuDarius D. Becker-KrailJames C. WaltonJames W. SimpkinsA. Courtney DeVriesRandy J. Nelson

neurologyvascular biologynight altersphysiologyrespiratory medicineneurosciencemembrane biologyacute exposurevascular structureneuroimagingartificial light

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicscrystal structurescrystal researchdeposited datasetstructural chemistryccdc 2157502crystal engineeringcrystallographystructure determinationstructure elucidationchemistrychemical structurecrystal diffraction study

Xanthine Oxidase Mediates Stress-Induced Alzheimer's Disease Progression in Triple Transgenic Mice. Physiology (2023)

Saina PrabhuEmily BurrageJenna LuthmanCrystal OudomvilayNatalia LunaRyan ChildersAlec HanshewPhillip EnglundVincent TiernoJacob HooverJames SimpkinsEric KelleyPaul Chantler

physiological researchalzheimer's diseaseneurogeneticsanimal physiologytriple transgenic micephysiologymedicinal researchneurosciencehuman biologystress-induced alzheimermolecular physiologyneurophysiologyxanthine oxidasemammalian biologygenetic basisgeneticsmammalian physiology

Blood Substitution—More Challenges for Translational Significance. Frontiers in Stroke (2022)

Xuefang Sophie RenHuimahn A. ChoiAaron M. GusdonHeng HuJude SavarrajAtzhiry PazRyan S. KitagawaJames W. Simpkins

blood substitutionneurologyhematologyneurosciencestrokegeneticstranslational significance

Chronic Stress Accelerates the Progression of Cerebrovascular Dysfunction With Alzheimer's Disease. The FASEB Journal (2022)

Emily N. BurrageSaina PrabhuJames FrazierJames SimpkinsEric E. KelleyPaul D. Chantler

neurologyalzheimer's diseasechronic stressrespiratory medicineneuroscienceneurodegenerative diseasesdegenerative diseasecerebrovascular dysfunctioncerebrovascular diseasehealth sciences

Chronic Stress Exacerbates Tau Production in the 3Xtg Alzheimer’s Disease Mice. The FASEB Journal (2022)

Saina PrabhuEmily BurrageJames SimpkinsEric KelleyPaul Chantler

neurologyalzheimer's diseasetau productionchronic stressneurosciencegenetics

1
2
3
4
5
43
10 / page

James W. Simpkins

Professor

West Virginia University

Affiliations

School of Medicine

Neuroscience

James W. Simpkins is currently serving as a Neuroscience Professor at West Virginia University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James W. Simpkins

West Virginia University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Brain-Wide Transgene Expression in Mice by Systemic Injection of Genetically Engineered Exosomes: Cap-Exosomes. Pharmaceuticals (2024)

Saumyendra N. SarkarDeborah CorbinJames W. Simpkins

genetic engineeringbrain-wide transgene expressionpharmaceutical sciencesneurosciencepharmacologymedicinesystemic injectionpharmaceutical research

Chronic Stress Mediates Cerebral Blood Flow Alterations via Xanthine Oxidase in an Early-Onset Alzheimer's Disease Model. Free Radical Biology and Medicine (2024)

Saina PrabhuNicole EminhizerAlec HanshewSteven BallEric KelleyPaul ChantlerJames Simpkins

alzheimer's diseasechronic stressdisease modelstress (biology)neurodegenerative diseasescerebral blood flowxanthine oxidaseearly-onset alzheimermedicinefree radical biology

Prospective Study of Extracellular Vesicles in Plasma as Potential Biomarkers for Silent Brain Infarcts (P10-4.013). Neurology (2024)

Lincey WilsonDuaa DakhlallahAnna ZukowskiJacob RalstonKate KarelinaJames SimpkinsMuhammad AlviCandace Brown

neurologyprospective studysilent brain infarctsbiomarkerscerebrovascular diseaseextracellular vesicles

Abstract Wp211: Mir-34A Modulates Outcomes After Experimental Stroke in Mice. Stroke (2023)

Xuefang RenSaumyendra SarkarMax EvansJames SimpkinsLena O'KeefeAaron GusdonRyan KitagawaHuimahn ChoiHeng Hu

neurologyexperimental strokemicrorna detectionneurosciencestroke

Acute Exposure to Artificial Light at Night Alters Hippocampal Vascular Structure in Mice. iScience (2023)

neurologyvascular biologynight altersphysiologyrespiratory medicineneurosciencemembrane biologyacute exposurevascular structureneuroimagingartificial light

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Xanthine Oxidase Mediates Stress-Induced Alzheimer's Disease Progression in Triple Transgenic Mice. Physiology (2023)

Saina PrabhuEmily BurrageJenna LuthmanCrystal OudomvilayNatalia LunaRyan ChildersAlec HanshewPhillip EnglundVincent TiernoJacob HooverJames SimpkinsEric KelleyPaul Chantler

Blood Substitution—More Challenges for Translational Significance. Frontiers in Stroke (2022)

Xuefang Sophie RenHuimahn A. ChoiAaron M. GusdonHeng HuJude SavarrajAtzhiry PazRyan S. KitagawaJames W. Simpkins

blood substitutionneurologyhematologyneurosciencestrokegeneticstranslational significance

Chronic Stress Accelerates the Progression of Cerebrovascular Dysfunction With Alzheimer's Disease. The FASEB Journal (2022)

Emily N. BurrageSaina PrabhuJames FrazierJames SimpkinsEric E. KelleyPaul D. Chantler

neurologyalzheimer's diseasechronic stressrespiratory medicineneuroscienceneurodegenerative diseasesdegenerative diseasecerebrovascular dysfunctioncerebrovascular diseasehealth sciences

Chronic Stress Exacerbates Tau Production in the 3Xtg Alzheimer’s Disease Mice. The FASEB Journal (2022)

Saina PrabhuEmily BurrageJames SimpkinsEric KelleyPaul Chantler

neurologyalzheimer's diseasetau productionchronic stressneurosciencegenetics

1
2
3
4
5
43
10 / page

Similar Faculty Members

Juan M. Saavedra

Institution

Georgetown University

free radical biology

neuroprotection

Greg Gerhardt

Institution

University of Kentucky

degenerative disease

degenerative pathology

Randy Nelson

Institution

West Virginia University

circadian rhythms

nervous system

Suresh C. Tyagi

Institution

University of Louisville

health science

cardiovascular translational research

Daria Mochly-Rosen

Institution

Stanford University

pharmacology

cardiology

Frank Sharp

Institution

University of California, Davis

cerebrovascular disease

cerebral blood flow

William Mack, MD

Institution

University of Southern California

cerebrovascular intervention

cerebrovascular disease

Joseph LaManna

Institution

Case Western Reserve University

free radical biology

cerebral blood flow

Joel S. Perlmutter

Institution

Washington University in St. Louis

neuroscience

huntington's disease

Craig W. Lindsley, Ph.D

Institution

Vanderbilt University

neuroscience

medicine

Similar Faculty Members

Juan M. Saavedra

Institution

Georgetown University

free radical biology

neuroprotection

Greg Gerhardt

Institution

University of Kentucky

degenerative disease

degenerative pathology

Randy Nelson

Institution

West Virginia University

circadian rhythms

nervous system

Suresh C. Tyagi

Institution

University of Louisville

health science

cardiovascular translational research

Daria Mochly-Rosen

Institution

Stanford University

pharmacology

cardiology

Frank Sharp

Institution

University of California, Davis

cerebrovascular disease

cerebral blood flow

William Mack, MD

Institution

University of Southern California

cerebrovascular intervention

cerebrovascular disease

Joseph LaManna

Institution

Case Western Reserve University

free radical biology

cerebral blood flow

Joel S. Perlmutter

Institution

Washington University in St. Louis

neuroscience

huntington's disease

Craig W. Lindsley, Ph.D

Institution

Vanderbilt University

neuroscience

medicine