James P. Long

James P. Long is an Associate Professor at The University of Texas MD Anderson Cancer Center. His research integrates cancer biology, immunology, and systems biology, with a focus on tumor microenvironments and therapeutic response prediction. Recent work includes identifying systemic immune correlates of long-term survival in recurrent glioblastoma treated with Delta-24-RGD adenovirus, characterizing AXL-driven immunosuppressive macrophage polarization in inflammatory breast cancer, and developing multiparametric MRI and cyst fluid protein biomarkers to stratify malignant risk in pancreatic ductal adenocarcinoma and intraductal papillary mucinous neoplasms. He also advances computational oncology through digital twin frameworks and improved metrics, such as AUC-PR, for evaluating in silico cellular perturbation models. His translational research bridges pharmacology, urology, and health sciences to improve precision cancer diagnostics and immunotherapy outcomes.