Faculty

Institution

Unit

Venue

James Coghill

Associate Professor of Medicine

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Medicine

James Coghill is currently serving as a Medicine Associate Professor of Medicine at University of North Carolina At Chapel Hill.

Honors

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Experiences

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Education

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James Coghill

University of North Carolina at Chapel Hill

Associate Professor of Medicine

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hematology immunology medicine regenerative medicine cell transplantation transplantation medicine clinical transplantation dermatology pharmacology immune responses bone marrow transplantation organ transplantation oncology medicinal research stem cell transplantation cellular therapy adaptive immune system t-regulatory cell clinical immunology cellular immune responses hiv innate immune system cell therapy cancer treatment stem cells liver transplantation blood cells graft rejection graft survival respiratory medicine leukemia experimental medicine stem cell research transplantation proceeding cytokines graft-versus-host disease acute graft-versus-host disease acute gvhd cell signaling transplant surgery lymphoid neoplasia chronic gvhd transplant infectious diseases thrombosis treatment development pathway analysis cutaneous biology host factors pharmacokinetics graft-versus-leukemia responses clinical investigation mammalian biology enzyme inhibition differential diagnosis treatment and prevention clinical medicine immune dysregulation clinical infectious disease acute medicine high-throughput screening discovery technique myeloid neoplasia immunohaematology immunologic diseases molecular immunology pulmonary pathologic manifestations baff-mediated pathways murine graft-versus-host disease safety switch transcription factor rorgt cutaneous chronic gvhd lineage fidelity chronic skin gvhd ptreg cells gastrointestinal tract t-cell expression hematological malignancies pathology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Alvr106, an Off-The-Shelf, Multivirus-Specific T-Cell Therapy, for the Treatment of Respiratory Viral Infections: Results From a Phase 1, First-In-Human, Dose-Ranging Trial. Transplantation and Cellular Therapy (2024)

Sarah NikiforowMitchell HorowitzJohn M. McCartyAnum AbbasJames CoghillJenny StantonJulie MaSpyridoula VasileiouSarah GilmoreDr. Bhagirathbhai DholariaRabi HannaRandy Allison TaplitzRajat Bansal

dose-ranging trialimmunologyimmunotherapycellular therapyrespiratory viral infectionsmultivirus-specific t-cell therapytransplantation medicine

Anti-Cd30 Car T Cells as Consolidation After Autologous Haematopoietic Stem-Cell Transplantation in Patients With High-Risk Cd30+ Lymphoma: A Phase 1 Study. The Lancet Haematology (2024)

Natalie S GroverGeorge HucksMarcie L RichesAnastasia IvanovaDominic T MooreThomas C SheaMary Beth SeegarsPaul M ArmisteadKimberly A KasowAnne W BeavenChristopher DittusJames M CoghillKatarzyna J JamiesonBenjamin G VincentWilliam A WoodCatherine ChengJulia Kaitlin MorrisonJohn WestTammy CavalloGianpietro DottiJonathan S SerodyBarbara Savoldo

immunohaematologyhaematopoiesiscancer immunotherapylymphoid neoplasiaimmunologycell transplantationhepatologyhematologycellular therapymedicinal researchclinical immunologypharmacologymedicineclinical transplantationcancer treatmentleukemiaoncologymyeloid neoplasia

Safety and Efficacy of Cd30.Car-T Cells as Consolidation Post Autologous Transplant in High-Risk Cd30 Lymphoma. (2024)

Natalie GroverGeorge HucksMarcie RichesAnastasia IvanovaDominic MooreThomas SheaMary Beth SeegarsPaul ArmisteadKimberly KasowAnne BeavenChristopher DittusJames CoghillKatarzyna JamiesonBenjamin VincentWilliam WoodCatherine ChengJ. Kaitlin MorrisonJohn WestTammy CavalloGianpietro DottiJonathan SerodyBarbara Savoldo

cell therapyorgan transplantationcancer immunotherapyclinical immunologyimmunologycell transplantationcancer treatmentdermatologyimmunotherapycellular therapycellular immune responsespharmacologyclinical transplantationpharmacotherapylymphoid neoplasiacancer careoncology

Abrogation of Immune Effector Cell Neurotoxicity Syndrome (Icans) by Rimiducid (Rim) in Patients Treated With Cd19-Specific Chimeric Antigen Receptor Modified T-Cells (Car-T) Engineered With an Inducible Caspase 9 (Ic9 Car.19)-Clinical and Pharmacodynamic Correlates. Blood (2022)

Matthew C. FosterBarbara SavoldoWinnie LauClio RubinosNatalie S. GroverPaul M. ArmisteadJames M. CoghillKatarzyna Joanna JamiesonRobert HaganJ. Kaitlin MorrisonFaith Brianne BuchananCatherine Joyce Arago ChengAnastasia IvanovaTammy CavalloJohn WestMegan GonzalezJonathan S. SerodyGianpietro Dotti

cancer immunotherapyimmunologymedicinal researchhematologycellular therapycell engineeringpharmacologymedicineclinical immunology

Contributors. Elsevier eBooks (2022)

Ron AltermanJeffrey E. ArleKerry BradleySergio CanaveroSteven M. FalowskiChad W. FarleyYakov GologorskyJianwen Wendy GuH. Louis JournéeJohn KastOlga KhazenJoachim K. KraussVignessh KumarMark LentRobert M. LevyAndres M. LozanoCharles MackelGeorge T. MandyburBryan L. McLaughlinDaniel R. MerrillAlon Y. MogilnerGabi MolnarGuillermo A. MonsalveRichard B. NorthYunseo Linda ParkJohn ParkerShrey PatelJulie G. PilitsisFrancisco A. PonceJason E. PopeAdolfo Ramirez-ZamoraLouis J. RasoJoshua M. RosenowJay L. ShilsPeter SingleKonstantin V. SlavinMichael D. StaudtMark M. SteckerHuy Q. Truong

Third-Party Type 2 Innate Lymphoid Cells Prevent and Treat Gi Tract Gvhd. Blood Advances (2021)

Danny W. BruceOleg KolupaevSonia J. LaurieHemamalini BommiasamyHeather StefanskiBruce R. BlazarJames M. CoghillJonathan S. Serody

immunologyhematologymedicinehealth sciencesinnate immune system

Utility of a Safety Switch to Abrogate Cd19.Car T-Cell–Associated Neurotoxicity. Blood (2021)

Matthew C. FosterBarbara SavoldoWinnie LauClio RubinosNatalie GroverPaul ArmisteadJames CoghillRobert S. HaganKaitlin MorrisonFaith Brianne BuchananCatherine ChengSpencer LaingAnastasia IvanovaJohn WestAaron FosterJonathan SerodyGianpietro Dotti

neurologysafety switchimmunologyhematologypharmacology

Influence of Germline Genetics on Tacrolimus Pharmacokinetics and Pharmacodynamics in Allogeneic Hematopoietic Stem Cell Transplant Patients. International Journal of Molecular Sciences (2020)

Jing ZhuTejendra PatelJordan A. MillerChad D. TorriceMehak AggarwalMargaret R. SketchMaurice D. AlexanderPaul M. ArmisteadJames M. CoghillTatjana GrgicKatarzyna J. JamiesonJonathan R. PtachcinskiMarcie L. RichesJonathan S. SerodyJohn L. SchmitzJ. Ryan ShawThomas C. SheaOscar SuzukiBenjamin G. VincentWilliam A. WoodKamakshi V. RaoTim WiltshireEric T. WeimerDaniel J. Crona

tacrolimus pharmacokineticsgermline geneticsrespiratory medicinehematologypharmacologymedicinegenetics

Peptide/Mhc Tetramer-Based Sorting of Cd8+ T Cells to a Leukemia Antigen Yields Clonotypes Drawn Nonspecifically From an Underlying Restricted Repertoire. UNC Libraries (2020)

Hunsucker, Sally A.McGary, Colleen S.Vincent, Benjamin G.Enyenihi, Atim A.Waugh, Jennifer P.McKinnon, Karen P.Bixby, Lisa M.Ropp, Patricia A.Coghill, James M.Wood, William A.Gabriel, Don A.Sarantopoulos, StefanieShea, Thomas C.Serody, Jonathan S.Alatrash, GheathRodriguez-Cruz, TaniaLizee, GregoryBuntzman, Adam S.Frelinger, Jeffrey A.Glish, Gary L.Armistead, Paul M.

t-regulatory celltechnologyimmunologycell biologypeptide sciencehematologyleukemiapeptideshematological malignanciesadaptive immune systemantigen processingreceptorshistocompatibility

R707, a Fully Human Antibody Directed Against CC-Chemokine Receptor 7, Attenuates Xenogeneic Acute Graft-Versus-Host Disease. American Journal of Transplantation (2019)

Kenneth A. FowlerViktoria VasilievaEkaterina IvanovaOlga RimkevichAndrey SokolovSvetlana AbbasovaEldar KimJames M. Coghill

transplant infectious diseasesimmunologic diseasesinfectious diseasesgraft rejectionimmunologyimmunotherapyimmune responsesimmunity (medicine)clinical transplantationgraft survivalhuman antibodyclinical immunologytransplantation medicine

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James Coghill

Associate Professor of Medicine

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Medicine

James Coghill is currently serving as a Medicine Associate Professor of Medicine at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James Coghill

University of North Carolina at Chapel Hill

Associate Professor of Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Sarah NikiforowMitchell HorowitzJohn M. McCartyAnum AbbasJames CoghillJenny StantonJulie MaSpyridoula VasileiouSarah GilmoreDr. Bhagirathbhai DholariaRabi HannaRandy Allison TaplitzRajat Bansal

dose-ranging trialimmunologyimmunotherapycellular therapyrespiratory viral infectionsmultivirus-specific t-cell therapytransplantation medicine

Anti-Cd30 Car T Cells as Consolidation After Autologous Haematopoietic Stem-Cell Transplantation in Patients With High-Risk Cd30+ Lymphoma: A Phase 1 Study. The Lancet Haematology (2024)

Safety and Efficacy of Cd30.Car-T Cells as Consolidation Post Autologous Transplant in High-Risk Cd30 Lymphoma. (2024)

cancer immunotherapyimmunologymedicinal researchhematologycellular therapycell engineeringpharmacologymedicineclinical immunology

Contributors. Elsevier eBooks (2022)

Third-Party Type 2 Innate Lymphoid Cells Prevent and Treat Gi Tract Gvhd. Blood Advances (2021)

Danny W. BruceOleg KolupaevSonia J. LaurieHemamalini BommiasamyHeather StefanskiBruce R. BlazarJames M. CoghillJonathan S. Serody

immunologyhematologymedicinehealth sciencesinnate immune system

Utility of a Safety Switch to Abrogate Cd19.Car T-Cell–Associated Neurotoxicity. Blood (2021)

neurologysafety switchimmunologyhematologypharmacology

Influence of Germline Genetics on Tacrolimus Pharmacokinetics and Pharmacodynamics in Allogeneic Hematopoietic Stem Cell Transplant Patients. International Journal of Molecular Sciences (2020)

tacrolimus pharmacokineticsgermline geneticsrespiratory medicinehematologypharmacologymedicinegenetics

Peptide/Mhc Tetramer-Based Sorting of Cd8+ T Cells to a Leukemia Antigen Yields Clonotypes Drawn Nonspecifically From an Underlying Restricted Repertoire. UNC Libraries (2020)

t-regulatory celltechnologyimmunologycell biologypeptide sciencehematologyleukemiapeptideshematological malignanciesadaptive immune systemantigen processingreceptorshistocompatibility

R707, a Fully Human Antibody Directed Against CC-Chemokine Receptor 7, Attenuates Xenogeneic Acute Graft-Versus-Host Disease. American Journal of Transplantation (2019)

Kenneth A. FowlerViktoria VasilievaEkaterina IvanovaOlga RimkevichAndrey SokolovSvetlana AbbasovaEldar KimJames M. Coghill

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