Faculty

Institution

Unit

Venue

James M. Briggs

Professor and UH Associate Provost for Faculty Development and Faculty Affairs

University of Houston

Affiliations

Honors College

Biology

College of Natural Sciences and Mathematics

Biology and Biochemistry

Cullen College of Engineering

Chemical and Biomolecular Engineering

James M. Briggs is currently serving as a Biology Professor and UH Associate Provost for Faculty Development and Faculty Affairs at University of Houston.

Honors

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Experiences

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Education

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James M. Briggs

University of Houston

Professor and UH Associate Provost for Faculty Development and Faculty Affairs

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pharmacology biophysics molecular biology protein science structural biology enzymes immunology molecular biophysics hiv drug discovery enzyme inhibition medicinal chemistry computational chemistry virology enzyme catalysis medicinal research structural molecular biology virus-host interactions protein chemistry computational biophysics experimental biophysics biological chemistry biophysical modeling pharmacotherapy antiviral therapy antiviral drug development viral genetics molecular docking mathematical biophysics biocatalysis molecular modeling alanine racemase brownian dynamics simulations active site nucleic acids virus research theoretical biology redox biology peptides bioelectrochemistry biomolecular interactions cancer genetics molecular substrates monte carlo simulations pk values molecular dynamics studies molecular dynamics simulation brain tumor research oncogenes leukemia quantum chemistry bioenergetics cancer biology cancer treatment cancer growth surface reactivity molecular electrochemistry pharmaceutical chemistry experimental pharmacology toxinology protein biosynthesis structure-function enzyme kinetics enzyme specificity tumor targeting protein transport pharmaceutical sciences rational drug design fluid simulations opls potential functions ionization states charge-charge interactions ionizable groups electrostatic steering amino acid cluster analysis continuum modeling protein design protein structure molecular design biochemistry biomolecular engineering computer-aided molecular design inhibitor design

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Autoinhibition Mechanism of the C-Terminal Extension of Human Serca2b. (2024)

Rulong MaJames M. Briggs

molecular biologygeneticsautoinhibition mechanismc-terminal extension

The Tilting Motion of the Central Core Reveals the Transport Mechanism of the Sarco/Endoplasmic Reticulum Ca2+-Atpase. International Journal of Biological Macromolecules (2024)

Rulong MaJames M. Briggs

biological macromoleculesbiophysicsmolecular biophysicstransport mechanismmembrane transportprotein structureprotein transportrelease mechanismenzymesmolecular biologystructural molecular biologymacromolecular systemsstructural biologyprotein sciencemacromolecular sciencemembrane biologymolecular physiologycell biology

Antibody MIX-And-Read Assays Based on Fluorescence Intensity Probes. mAbs (2021)

Ujwal PatilAtul GoyalBinh VuYanyun LiuVijay MaranholkarKaterina KourentziJames M. BriggsRichard C. Willson

immunologypharmacologyantibody mix-and-read assaysfluorescence intensity probesinstrumentation

Heterotropic Roles of Divalent Cations in the Establishment of Allostery and Affinity Maturation of Integrin Αxβ2. SSRN Electronic Journal (2021)

Pragya ManandharZahra MazharZeinab MoussaOmar AbousawayCollins AboagyeDaniel LimTannon YuJames ByrnesJames M. BriggsMehmet Sen

immunologycellular physiologymolecular and cellular biologycell physiologymolecular biologycell-matrix interactionsdivalent cationsaffinity maturationcellular biologymembrane biologyheterotropic rolescell biology

Impact of Lymphoma‐Linked Asn11Tyr Point Mutation on the Interaction Between Bcl‐2 and a Bh3 Mimetic: Insights From Molecular Dynamics Simulation. Chemical Biology & Drug Design (2020)

Khushboo SinghJames M. Briggs

pharmacologycancer geneticsrational drug designmolecular dynamics simulationchemical biologydrug discoverymolecular biologychemistry

Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands With Inverse Agonist and Degrader Activity. ACS Chemical Biology (2020)

Husna KarabogaWentao HuangShivangi SrivastavaScott WidmannSridevi AddankiKasuni Thawalama GamageZahra MazharJerry O. EbalunodeJames M. BriggsJan-Åke GustafssonCarly S. FilgueiraScott R. GilbertsonChin-Yo Lin

medicinal chemistrylead identificationpancreatic cancerdrug targetstumor targetingclinical chemistrydegrader activitydermatologyurologyhepatologydrug targetingtumor biologyenzyme inhibitionpharmacologyredox biologyinverse agonistdrug discoveryoncologymedicinal researchcellular therapyfocused compound library

Discovery of Vascular Rho Kinase (Rock) Inhibitory Peptides. Experimental Biology and Medicine (2019)

Reza AbbasgholizadehHua ZhangJohn W CraftRobert M BryanSteven J BarkJames M BriggsRobert O FoxAnton AgarkovWarren E ZimmerScott R GilbertsonRobert J Schwartz

physiologyinhibitory peptidesenzyme inhibitionpharmacologyvascular biologyneurosciencedrug discoveryvascular rho kinaseexperimental pharmacologyprotein scienceexperimental medicineexperimental biology

Insights Into the Substrate Binding Specificity of Quorum-Quenching Acylase Pvdq. Journal of Molecular Graphics and Modelling (2019)

Yanyun LiuJerry O. EbalunodeJames M. Briggs

pharmacologybiochemical engineeringapplied microbiologymolecular modellingenzymesbiomolecular engineeringstructural biologyprotein engineeringbiological engineeringquorum-quenching acylase pvdq

RNADEMOCRACY: An Ensemble Method for Rna Secondary Structure Prediction Using Consensus Scoring. Computational Biology and Chemistry (2019)

Benjamin L. SkidmoreJames M. Briggs

computational biologymolecular biologyensemble methodbioinformatics

Immobilization and Unbinding Investigation of the Antigen-Antibody Complex Using Theoretical and Experimental Techniques. Journal of Molecular Graphics and Modelling (2018)

Guedmiller S. OliveiraJéssica C.M. IerichAriana S. MoraesGisela B.R.F. SilvaYanyun LiuLourival R. de S. NetoRoberto R. FariaEduardo F. FrancaLuiz C.G. FreitasJames M. BriggsFabio L. Leite

immunologyexperimental techniquespharmacologymolecular modellingunbinding investigationantigen-antibody complexapplied mathematicsenzyme immobilization

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James M. Briggs

Professor and UH Associate Provost for Faculty Development and Faculty Affairs

University of Houston

Affiliations

Honors College

Biology

College of Natural Sciences and Mathematics

Biology and Biochemistry

Cullen College of Engineering

Chemical and Biomolecular Engineering

James M. Briggs is currently serving as a Biology Professor and UH Associate Provost for Faculty Development and Faculty Affairs at University of Houston.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James M. Briggs

University of Houston

Professor and UH Associate Provost for Faculty Development and Faculty Affairs

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Autoinhibition Mechanism of the C-Terminal Extension of Human Serca2b. (2024)

Rulong MaJames M. Briggs

molecular biologygeneticsautoinhibition mechanismc-terminal extension

The Tilting Motion of the Central Core Reveals the Transport Mechanism of the Sarco/Endoplasmic Reticulum Ca2+-Atpase. International Journal of Biological Macromolecules (2024)

Rulong MaJames M. Briggs

Antibody MIX-And-Read Assays Based on Fluorescence Intensity Probes. mAbs (2021)

Ujwal PatilAtul GoyalBinh VuYanyun LiuVijay MaranholkarKaterina KourentziJames M. BriggsRichard C. Willson

immunologypharmacologyantibody mix-and-read assaysfluorescence intensity probesinstrumentation

Heterotropic Roles of Divalent Cations in the Establishment of Allostery and Affinity Maturation of Integrin Αxβ2. SSRN Electronic Journal (2021)

Pragya ManandharZahra MazharZeinab MoussaOmar AbousawayCollins AboagyeDaniel LimTannon YuJames ByrnesJames M. BriggsMehmet Sen

Impact of Lymphoma‐Linked Asn11Tyr Point Mutation on the Interaction Between Bcl‐2 and a Bh3 Mimetic: Insights From Molecular Dynamics Simulation. Chemical Biology & Drug Design (2020)

Khushboo SinghJames M. Briggs

pharmacologycancer geneticsrational drug designmolecular dynamics simulationchemical biologydrug discoverymolecular biologychemistry

Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands With Inverse Agonist and Degrader Activity. ACS Chemical Biology (2020)

Discovery of Vascular Rho Kinase (Rock) Inhibitory Peptides. Experimental Biology and Medicine (2019)

Reza AbbasgholizadehHua ZhangJohn W CraftRobert M BryanSteven J BarkJames M BriggsRobert O FoxAnton AgarkovWarren E ZimmerScott R GilbertsonRobert J Schwartz

Insights Into the Substrate Binding Specificity of Quorum-Quenching Acylase Pvdq. Journal of Molecular Graphics and Modelling (2019)

Yanyun LiuJerry O. EbalunodeJames M. Briggs

pharmacologybiochemical engineeringapplied microbiologymolecular modellingenzymesbiomolecular engineeringstructural biologyprotein engineeringbiological engineeringquorum-quenching acylase pvdq

RNADEMOCRACY: An Ensemble Method for Rna Secondary Structure Prediction Using Consensus Scoring. Computational Biology and Chemistry (2019)

Benjamin L. SkidmoreJames M. Briggs

computational biologymolecular biologyensemble methodbioinformatics

Immobilization and Unbinding Investigation of the Antigen-Antibody Complex Using Theoretical and Experimental Techniques. Journal of Molecular Graphics and Modelling (2018)

Guedmiller S. OliveiraJéssica C.M. IerichAriana S. MoraesGisela B.R.F. SilvaYanyun LiuLourival R. de S. NetoRoberto R. FariaEduardo F. FrancaLuiz C.G. FreitasJames M. BriggsFabio L. Leite

immunologyexperimental techniquespharmacologymolecular modellingunbinding investigationantigen-antibody complexapplied mathematicsenzyme immobilization

1
2
3
4
5
11
10 / page

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materials science

biophysics

Robert J Woods

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glycosylation

carbohydrate chemistry

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biomolecular structure

computational biology

Matthias Buck

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protein-membrane interactions

molecular pathway

Steven D. Schwartz

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molecular informatics

computational biology

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mechanistic kinetics

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molecular docking

protein structural dynamics

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molecular informatics

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public performance

performance theory