Faculty

Institution

Unit

Venue

John Gerlt

Gutgsell Chair Emeritus Professor Emeritus of Biochemistry and Professor Emeritus of Chemistry

UIUC

Affiliations

College of Liberal Arts & Sciences

Department of Biochemistry

School of Molecular & Cellular Biology

Department of Biochemistry

John Gerlt is currently serving as a College Of Liberal Arts & Sciences Gutgsell Chair Emeritus Professor Emeritus of Biochemistry and Professor Emeritus of Chemistry at Uiuc.

Honors

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Experiences

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Education

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John Gerlt

UIUC

Gutgsell Chair Emeritus Professor Emeritus of Biochemistry and Professor Emeritus of Chemistry

You can click a keyword to filter the displayed items

biochemistry enzymes molecular biology enzyme catalysis structure-function enzyme kinetics structural molecular biology biological chemistry enzyme inhibition protein structure biomolecular structure biomolecular engineering biocatalysis protein science structural biology molecular metabolism biosynthesis chemical biology biochemical sciences microbiology altmetric attention score biomolecules metabolic pathways enzyme specificity protein x-ray crystallography crystal structures enzymatic modification enolase superfamily chemical sciences active site bioinformatics molecular microbiology escherichia coli nucleic acids process biochemistry cellular enzymology catalysis nucleic acid chemistry protein biosynthesis proteome research genome biology organic process research molecular informatics cell metabolism metabolic pathway analysis protein bioinformatics directed evolution metabolic networks oligonucleotides protein chemistry protein evolution bacteriology pathway analysis biomolecular analysis donut icon mandelate racemase microbial physiology pseudomonas putida bioinformatics database protein structure prediction proton transfer acid sugars reaction intermediates dna analysis biochemical genetics hydrogen bond carbon acids crotonase superfamily biological databases microbial genetics protein synthesis essential mg2+ enzyme function initiative divergent evolution functional annotation functional assignment enzyme function mutagenesis (molecular biology technique) intermediary metabolism mechanistic enzymology

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Efi-Est, Efi-Gnt, and Efi-Cgfp: Enzyme Function Initiative (Efi) Web Resource for Genomic Enzymology Tools. Journal of Molecular Biology (2023)

Nils ObergRémi ZallotJohn A. Gerlt

proteomicsfunctional genomicssystems biologyproteome researchprotein bioinformaticsenzyme function initiativeenzymescellular enzymologygenomic enzymology toolsmolecular biologyprotein sciencemolecular informaticsweb resource

Pyridoxal 5’-Phosphate Synthesis and Salvage in Bacteria and Archaea: Predicting Pathway Variant Distributions and Holes. Microbial Genomics (2023)

Rémi DeniseJill BaborJohn A. GerltValérie de Crécy-Lagard

genome biologyseveral plpmolecular microbiologybacteriologybiologymicrobial geneticsmicrobial systematicsmolecular metabolismmolecular biologybiological chemistryplp synthesisbacteriabioenergeticsmicrobiologyplp synthesis enzymesbiosynthesis

A Roadmap for the Functional Annotation of Protein Families: A Community Perspective. Database (2022)

Valérie de Crécy-lagardRocio Amorin de HegedusCecilia ArighiJill BaborAlex BatemanIan BlabyCrysten Blaby-HaasAlan J BridgeStephen K BurleyStacey ClevelandLucy J ColwellAna ConesaChristian DallagoAntoine DanchinAnita de WaardAdam DeutschbauerRaquel DiasYousong DingGang FangIddo FriedbergJohn GerltJoshua GoldfordMark GorelikBenjamin M GyoriChristopher HenryGeoffrey HutinetMarshall JarochPeter D KarpLiudmyla KondratovaZhiyong LuAron Marchler-BauerMaria-Jesus MartinClaire McWhiteGaurav D MoghePaul MonaghanAnne MorgatChristopher J MungallDarren A NataleWilliam C NelsonSeán O’DonoghueChristine OrengoKatherine H O’ToolePredrag RadivojacColbie ReedRichard J RobertsDmitri RodionovIrina A RodionovaJeffrey D RudolfLana SalehGloria SheynkmanFrancoise Thibaud-NissenPaul D ThomasPeter UetzDavid VallenetErica Watson CarterPeter R WeigeleValerie WoodElisha M Wood-CharlsonJin Xu

genomicsgenome biologybiomedical informaticsfunctional annotationfunctional genomicssystems biologyprotein bioinformaticsgeneticscommunity perspectiveprotein familiesgene sequence annotationprotein sciencemolecular informaticsbioinformatics

Radical Sam Enzymes and the Unexplored Chemistry of Ripp Biosynthesis. The FASEB Journal (2022)

Douglas MitchellTimothy PrecordGraham HudsonNilkamal MahantaBrandon BurkhartJohn Gerlt

protein structure predictionradical sam enzymesprotein structurersam domainbiomolecular structureenzymesmolecular biologybiological chemistrystructural molecular biologystructural bioinformaticsstructural biologyprotein scienceripp biosynthesisbiochemistrybioinformatics

Discovery of New Enzymatic Functions and Metabolic Pathways Using Genomic Enzymology Web Tools. Current Opinion in Biotechnology (2021)

Remi ZallotNils ObergJohn A Gerlt

metabolic pathway analysismetabolic networksbiomolecular engineeringmolecular metabolismnew enzymatic functionsenzymatic modificationmetabolic pathwayscell metabolismbiochemistrybioinformatics

Epoxyqueuosine Reductase Queh in the Biosynthetic Pathway to Trna Queuosine is a Unique Metalloenzyme. Biochemistry (2021)

Qiang LiRémi ZallotBrian S. MacTavishAlvaro MontoyaDaniel J. PayanYou HuJohn A. GerltAlexander AngerhoferValérie de Crécy-LagardSteven D. Bruner

epoxyqueuosine reductase quehbiomolecular structurechemical biologyenzymesnucleic acidsbiological inorganic chemistrymolecular biologybiological chemistrystructural molecular biologybioorganometallic chemistrytrna modificationstructural biologyqueuosine biosynthesisbiochemistrybiosynthesis

Evolution of Enzyme Function and the Development of Catalytic Efficiency: Triosephosphate Isomerase, Jeremy R. Knowles, and W. John Albery. Biochemistry (2021)

John A. Gerlt

enzyme inhibitionstructure-function enzyme kineticstriosephosphate isomeraseenzyme specificitybiomolecular engineeringenzymesmolecular metabolismbiocatalysisenzyme catalysisenzyme functioncatalytic efficiencybiochemistrybiosynthesis

Radicalsam.Org: A Resource to Interpret Sequence-Function Space and Discover New Radical Sam Enzyme Chemistry. ACS Bio & Med Chem Au (2021)

Nils ObergTimothy W. PrecordDouglas A. MitchellJohn A. Gerlt

genomicsgenome biologysequence analysisfunctional genomicsenzymatic activitiessequence alignmentradical sam enzymesradical sammolecular biologycomputational biologymolecular informaticsmicrobiologybioinformatics

A Bifunctional Salvage Pathway for Two Distinct S‐Adenosylmethionine by‐Products That is Widespread in Bacteria, Including Pathogenic Escherichia Coli. Molecular Microbiology (2020)

Justin A. NorthJohn A. WildenthalTobias J. ErbBradley S. EvansKathryn M. ByerlyJohn A. GerltFred R. Tabita

enzyme inhibitionmicrobial physiologymolecular microbiologyradical samsulfur salvageenzymesmolecular metabolismbiological chemistrymicrobial cell factoryescherichia colibiomoleculesbacteriamicrobiologybiochemistry

Characterization of an L -Ascorbate Catabolic Pathway With Unprecedented Enzymatic Transformations. Journal of the American Chemical Society (2020)

Tyler M. M. StackKatelyn N. MorrisonThomas M. DettmerBrendan WilleChan KimRyan JoyceMadison JermainYadanar Than NaingKhadija BhattiBrian San FranciscoMichael S. CarterJohn A. Gerlt

vitamin cpdxa familybiochemical geneticsmolecular metabolismprotein biosynthesismolecular biologymetabolic pathwaysmetabolic engineeringgene deletion mutantsbiochemistrycell metabolism

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John Gerlt

Gutgsell Chair Emeritus Professor Emeritus of Biochemistry and Professor Emeritus of Chemistry

UIUC

Affiliations

College of Liberal Arts & Sciences

Department of Biochemistry

School of Molecular & Cellular Biology

Department of Biochemistry

John Gerlt is currently serving as a College Of Liberal Arts & Sciences Gutgsell Chair Emeritus Professor Emeritus of Biochemistry and Professor Emeritus of Chemistry at Uiuc.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Gerlt

UIUC

Gutgsell Chair Emeritus Professor Emeritus of Biochemistry and Professor Emeritus of Chemistry

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Efi-Est, Efi-Gnt, and Efi-Cgfp: Enzyme Function Initiative (Efi) Web Resource for Genomic Enzymology Tools. Journal of Molecular Biology (2023)

Nils ObergRémi ZallotJohn A. Gerlt

Pyridoxal 5’-Phosphate Synthesis and Salvage in Bacteria and Archaea: Predicting Pathway Variant Distributions and Holes. Microbial Genomics (2023)

Rémi DeniseJill BaborJohn A. GerltValérie de Crécy-Lagard

A Roadmap for the Functional Annotation of Protein Families: A Community Perspective. Database (2022)

Radical Sam Enzymes and the Unexplored Chemistry of Ripp Biosynthesis. The FASEB Journal (2022)

Douglas MitchellTimothy PrecordGraham HudsonNilkamal MahantaBrandon BurkhartJohn Gerlt

Discovery of New Enzymatic Functions and Metabolic Pathways Using Genomic Enzymology Web Tools. Current Opinion in Biotechnology (2021)

Remi ZallotNils ObergJohn A Gerlt

metabolic pathway analysismetabolic networksbiomolecular engineeringmolecular metabolismnew enzymatic functionsenzymatic modificationmetabolic pathwayscell metabolismbiochemistrybioinformatics

Epoxyqueuosine Reductase Queh in the Biosynthetic Pathway to Trna Queuosine is a Unique Metalloenzyme. Biochemistry (2021)

Qiang LiRémi ZallotBrian S. MacTavishAlvaro MontoyaDaniel J. PayanYou HuJohn A. GerltAlexander AngerhoferValérie de Crécy-LagardSteven D. Bruner

Evolution of Enzyme Function and the Development of Catalytic Efficiency: Triosephosphate Isomerase, Jeremy R. Knowles, and W. John Albery. Biochemistry (2021)

John A. Gerlt

Radicalsam.Org: A Resource to Interpret Sequence-Function Space and Discover New Radical Sam Enzyme Chemistry. ACS Bio & Med Chem Au (2021)

Nils ObergTimothy W. PrecordDouglas A. MitchellJohn A. Gerlt

A Bifunctional Salvage Pathway for Two Distinct S‐Adenosylmethionine by‐Products That is Widespread in Bacteria, Including Pathogenic Escherichia Coli. Molecular Microbiology (2020)

Justin A. NorthJohn A. WildenthalTobias J. ErbBradley S. EvansKathryn M. ByerlyJohn A. GerltFred R. Tabita

Characterization of an L -Ascorbate Catabolic Pathway With Unprecedented Enzymatic Transformations. Journal of the American Chemical Society (2020)

Tyler M. M. StackKatelyn N. MorrisonThomas M. DettmerBrendan WilleChan KimRyan JoyceMadison JermainYadanar Than NaingKhadija BhattiBrian San FranciscoMichael S. CarterJohn A. Gerlt

vitamin cpdxa familybiochemical geneticsmolecular metabolismprotein biosynthesismolecular biologymetabolic pathwaysmetabolic engineeringgene deletion mutantsbiochemistrycell metabolism

1
2
3
4
5
28
10 / page