Faculty

Institution

Unit

Venue

Irvin Chen

Distinguished Professor Professor of Microbiology Immunology Molecular Genetics and Professor of Medicine

University of California, Los Angeles

Affiliations

the College

Microbiology, Immunology, and Molecular Genetics

Molecular Biology Institute (mbi)

Irvin Chen is currently serving as a Microbiology, Immunology, And Molecular Genetics Distinguished Professor Professor of Microbiology Immunology Molecular Genetics and Professor of Medicine at University of California, Los Angeles.

Honors

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Experiences

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Education

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Irvin Chen

University of California, Los Angeles

Distinguished Professor Professor of Microbiology Immunology Molecular Genetics and Professor of Medicine

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immunology virology hiv genetics virus research viral genetics medicine general virology gene expression molecular biology medical virology virus-host interactions gene therapy viral pathogenesis hematology immune responses viral oncology molecular virology clinical microbiology adaptive immune system infection control medicinal research mammalian biology nanomedicine regenerative medicine leukemia stem cell research viral evolution human retrovirus cell death rna biology clinical immunology antiviral therapy gene delivery antibody engineering cellular therapy transcription regulation apoptosis gene vector nanobiotechnology virus transmission tumor targeting antiviral research gene regulation virus epidemiology drug targeting lentiviral vectors plo biology respiratory medicine viral replication lentiviral vector enzyme inhibition cell regulation molecular regulation hiv infection rhesus macaques genome biology gene function gene transfer pharmaceutical nanotechnology genetic technologies medical genetics host response hematological malignancies intravenous injection putative transforming protein nerve growth factors neural regeneration non-human primates bioinspired platform protein therapeutics retroviral vectors nonhuman primates lentivirus vector humanized blt mice envelope proteins

Notable Scholarly Works

Notable Federal Grants

Collaborators

Lentivirus-Based Hpsc Therapy Provides Effective and Long-Term Treatment in Hypophosphatasia Mouse Model. Molecular Therapy (2026)

virologyviral geneticslentivirus-based hpsc therapyinfectious diseaseslong-term treatmentmedical virologyvirus-host interactionshypophosphatasia mouse modelimmunity (medicine)immunologyviral pathogenesispathogenesismolecular medicinevirus research

Excision of Hiv-1 Provirus in Human Primary Cells With Nanocapsuled Talen Proteins. ACS Applied Bio Materials (2025)

hivvirologybiomolecular engineeringhuman retrovirusvirus research

A Multi‐Enzyme Nanocascade to Target Disease‐Relevant Metabolites. Small (2024)

Zheng CaoJie RenAlena YangZi WangMaxwell LoveWenting ChenXintong YuanXinheng GuoIrvin ChenYunfeng LuJing Wen

metabolic pathwaysbioassay-guided isolationenzymesbiomolecular engineeringmulti-enzyme nanocascadeenzyme catalysissystems biologybiochemistryenzyme specificitynanomedicinenanoparticle researchenzyme inhibitiondrug discoverynanobiotechnologydisease-relevant metabolites

Molecular Biology and Pathogenesis of Htlv-II. CRC Press eBooks (2024)

Alan J. CannJoesph D. RosenblattWilliam WachsmanIrvin S. Y. Chen

molecular biologypathogenesis

Cd3-Immunotoxin Mediated Depletion of T Cells in Lymphoid Tissues of Rhesus Macaques. Heliyon (2023)

Lan WangGajendra W. SuryawanshiShihyoung KimXin GuanAylin C. BonifacinoMark E. MetzgerRobert E. DonahueSanggu KimIrvin S.Y. Chen

immune responsesrhesus macaquesadaptive immune systemimmunologylymphoid tissuesinnate immune system

Lactate Oxidase Nanocapsules Boost T Cell Immunity and Efficacy of Cancer Immunotherapy. Science Translational Medicine (2023)

Zheng CaoDuo XuJeffrey HardingWenting ChenXiangsheng LiuZi WangLan WangTong QiShilin ChenXinheng GuoIrvin S. Y. ChenJimin GuoYunfeng LuJing Wen

cancer immunotherapytranslational medicinemedicineimmunotherapyimmunologypharmacologynanomedicinelactate oxidase nanocapsulesnanotechnologyvaccine efficacy

Cannabidiol Modulates Expression of Type I Ifn Response Genes and Hiv Infection in Macrophages. Frontiers in Immunology (2022)

Shallu TomerWenli MuGajendra SuryawanshiHwee NgLi WangWally WennerbergValerie RezekHeather MartinIrvin ChenScott KitchenAnjie Zhen

immune responseshost responseresponse genesimmunologygene expressionhealth scienceshiv infection

Efficient Derivation of Chimeric-Antigen Receptor-Modified Tscm Cells. Frontiers in Immunology (2022)

Emiko KranzCharles J. KuhlmannJoshua ChanPatrick Y. KimIrvin S. Y. ChenMasakazu Kamata

efficient derivationreceptorsimmunologyadaptive immune system

CORRECTION: Robust Car-T Memory Formation and Function via Hematopoietic Stem Cell Delivery. PLoS Pathogens (2021)

Anjie ZhenMayra A CarrilloWenli MuValerie RezekHeather MartinPhilip HamidIrvin S. Y. ChenOtto O. YangJerome A. ZackScott G. Kitchen

developmental biologymicrobiologyhematologystem cell researchcell manipulationdevelopmental neurobiologymemoryhaematopoiesisneuroregenerationvehicular technologyin vivo systemsplo biologyadaptive immune systemneuroscienceregenerative medicinecell transplantationcell researchhistocompatibility

Improved Delivery of Broadly Neutralizing Antibodies by Nanocapsules Suppresses Shiv Infection in the Cns of Infant Rhesus Macaques. PLoS Pathogens (2021)

Jing WenTracy CheeverLan WangDi WuJason ReedJohn MascolaXuejun ChenCuiping LiuAmarendra PeguJonah B. SachaYunfeng LuNancy L. HaigwoodIrvin S. Y. Chen

medicineinfection controlpharmacologynanobiotechnologyapplied microbiologynanotechnologyveterinary microbiologypharmaceutical nanotechnologyclinical microbiologyantiviral therapyimproved deliveryvirologyantibody engineeringinfant rhesus macaquesavian medicineveterinary medicineimmunologynanomedicineveterinary sciencedrug delivery

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Irvin Chen

Distinguished Professor Professor of Microbiology Immunology Molecular Genetics and Professor of Medicine

University of California, Los Angeles

Affiliations

the College

Microbiology, Immunology, and Molecular Genetics

Molecular Biology Institute (mbi)

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Irvin Chen

University of California, Los Angeles

Distinguished Professor Professor of Microbiology Immunology Molecular Genetics and Professor of Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Lentivirus-Based Hpsc Therapy Provides Effective and Long-Term Treatment in Hypophosphatasia Mouse Model. Molecular Therapy (2026)

Excision of Hiv-1 Provirus in Human Primary Cells With Nanocapsuled Talen Proteins. ACS Applied Bio Materials (2025)

hivvirologybiomolecular engineeringhuman retrovirusvirus research

A Multi‐Enzyme Nanocascade to Target Disease‐Relevant Metabolites. Small (2024)

Zheng CaoJie RenAlena YangZi WangMaxwell LoveWenting ChenXintong YuanXinheng GuoIrvin ChenYunfeng LuJing Wen

Molecular Biology and Pathogenesis of Htlv-II. CRC Press eBooks (2024)

Alan J. CannJoesph D. RosenblattWilliam WachsmanIrvin S. Y. Chen

molecular biologypathogenesis

Cd3-Immunotoxin Mediated Depletion of T Cells in Lymphoid Tissues of Rhesus Macaques. Heliyon (2023)

Lan WangGajendra W. SuryawanshiShihyoung KimXin GuanAylin C. BonifacinoMark E. MetzgerRobert E. DonahueSanggu KimIrvin S.Y. Chen

immune responsesrhesus macaquesadaptive immune systemimmunologylymphoid tissuesinnate immune system

Lactate Oxidase Nanocapsules Boost T Cell Immunity and Efficacy of Cancer Immunotherapy. Science Translational Medicine (2023)

Zheng CaoDuo XuJeffrey HardingWenting ChenXiangsheng LiuZi WangLan WangTong QiShilin ChenXinheng GuoIrvin S. Y. ChenJimin GuoYunfeng LuJing Wen

cancer immunotherapytranslational medicinemedicineimmunotherapyimmunologypharmacologynanomedicinelactate oxidase nanocapsulesnanotechnologyvaccine efficacy

Cannabidiol Modulates Expression of Type I Ifn Response Genes and Hiv Infection in Macrophages. Frontiers in Immunology (2022)

Shallu TomerWenli MuGajendra SuryawanshiHwee NgLi WangWally WennerbergValerie RezekHeather MartinIrvin ChenScott KitchenAnjie Zhen

immune responseshost responseresponse genesimmunologygene expressionhealth scienceshiv infection

Efficient Derivation of Chimeric-Antigen Receptor-Modified Tscm Cells. Frontiers in Immunology (2022)

Emiko KranzCharles J. KuhlmannJoshua ChanPatrick Y. KimIrvin S. Y. ChenMasakazu Kamata

efficient derivationreceptorsimmunologyadaptive immune system

CORRECTION: Robust Car-T Memory Formation and Function via Hematopoietic Stem Cell Delivery. PLoS Pathogens (2021)

Anjie ZhenMayra A CarrilloWenli MuValerie RezekHeather MartinPhilip HamidIrvin S. Y. ChenOtto O. YangJerome A. ZackScott G. Kitchen

Improved Delivery of Broadly Neutralizing Antibodies by Nanocapsules Suppresses Shiv Infection in the Cns of Infant Rhesus Macaques. PLoS Pathogens (2021)

Jing WenTracy CheeverLan WangDi WuJason ReedJohn MascolaXuejun ChenCuiping LiuAmarendra PeguJonah B. SachaYunfeng LuNancy L. HaigwoodIrvin S. Y. Chen

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Similar Faculty Members

Jianzhu Chen

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Similar Faculty Members

Jianzhu Chen

Institution

Massachusetts Institute of Technology

human diseases

nanoparticle research

Patrick Iversen

Institution

Oregon State University

molecular metabolism

molecular biology

Mohapatra, Shyam

Institution

University of South Florida

translational research

gene transfer

Alex K. Shalek

Institution

Massachusetts Institute of Technology

molecular features

immunology

Jenny Ting

Institution

University of North Carolina at Chapel Hill

gene discovery

innate immune system

Donald Kohn

Institution

University of California, Los Angeles

immunology

gene therapy

Drew Weissman

Institution

University of Pennsylvania

rna biology

mrna vaccines

Matteo Pellegrini

Institution

University of California, Los Angeles

gene expression

epigenetics

Owen Witte

Institution

University of California, Los Angeles

immunology

genetics

Kamel Khalili

Institution

Temple University

neuroscience

neurodegenerative disease