Faculty

Institution

Unit

Venue

Irina V Budunova

Professor

Northwestern University

Affiliations

Feinberg School of Medicine

Department of Dermatology

Department of Urology

Irina V Budunova is currently serving as a Dermatology Professor at Northwestern University.

Honors

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Experiences

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Education

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Irina V Budunova

Northwestern University

Professor

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dermatology pharmacology tumor biology oncology medicinal research cancer biology cancer research cell biology cutaneous biology inflammation gene expression molecular cancer genetics anti-cancer agents tumor targeting clinical dermatology carcinogenesis prostate cancer mammalian biology oncogenes skin cancer cancer treatment cancer care glucocorticoid receptor endocrinology enzyme inhibition glucocorticoids cancer cells leukemia cellular therapy cell regulation cancer genomics cancer genetics experimental dermatology drug targeting molecular cell biology tumor suppressors skin development cancer prevention cancer imaging pharmacotherapy dermatological treatment anti-cancer activity pharmaceutics cellular biology cancer growth cell cycle molecular regulation skin pharmacology signaling pathways prostate cancer cells selective activator topical glucocorticoids constitutive activation prostate carcinoma cells glucocorticoid-induced skin atrophy protein science cell death intercellular communication cell culture apoptosis in vivo systems transcription regulation knockout mice differential targeting mouse skin carcinogenesis tumor suppressor effect gene function inhibitory activity oncogenic agent innate immune system nf-kb transcription factor mouse skin tumorigenesis functional roles tumor suppressor activity tumor-inhibiting activity

Notable Scholarly Works

Notable Federal Grants

Collaborators

0625 Skin as a Potential Entry Point for Sars-Cov-2 Virus. Journal of Investigative Dermatology (2025)

viral pathogenesissars-cov-2virologyinfectious diseasesmedical virologypathogenesiscovid-19virus researchcommunicable diseasesvirus transmissionpotential entry pointdermatologygeneral virology

0703 Distinct Responses of 3D African American and White Non-Hispanic Skin Organoids to Key Pro-Inflammatory Cytokines. Journal of Investigative Dermatology (2025)

inflammationdermatological treatmentcutaneous biologyexperimental dermatologyimmunologydermatologyimmune responsesexperimental medicineclinical dermatology

0925 Redd1/Ddit4 Knockout Prevents Skin Atrophy in Aged Mice. Journal of Investigative Dermatology (2025)

knockout miceaged miceaging celldermatologyneurodegenerative diseases

Anticancer Plant Secondary Metabolites Evicting Linker Histone H1.2 From Chromatin Activate Type I Interferon Signaling. International Journal of Molecular Sciences (2025)

Olga VlasovaIrina AntonovaKhamis MagomedovaAlena OsipovaPolina ShtompelAnna BorunovaTatiana ZabotinaGennady BelitskyIrina BudunovaAlbert JordanKirill KirsanovMarianna Yakubovskaya

molecular cell biologygene expressiononcogenesgene regulatory networkscancer genomicsbiochemistryvirus researchmolecular biologymolecular sciencesystems biologycell signalingtumor biologystructural molecular biologysecondary metabolitessignaling pathwaysmolecular and cellular biologychromatinepigenomics

Il-1 Signaling Enrichment in Inflammatory Skin Disease Loci With Higher Risk Allele Frequencies in African Ancestry. Research Square (2025)

inflammationdermatological treatmentafrican ancestryimmune dysregulationautoinflammatory diseaseimmune-related gene polymorphismautoimmune diseasesimmunologydermatologyimmune responsesrheumatisminflammatory diseaseshigher risk

Skin Microbiota Differs Between Black and White Patients With Cutaneous T-Cell Lymphoma. Journal of the American Academy of Dermatology (2025)

cutaneous t-cell lymphomapsoriasisdermatological treatmentcutaneous biologyskin microbiota differsimmunologydermatologycosmetic dermatologyimmune responseswhite patientssclerodermaclinical dermatology

533 Racial Differences in the Skin Microbiome of Cutaneous T-Cell Lymphoma Patients Are Not Present in That of Healthy Individuals. Journal of Investigative Dermatology (2024)

Y. PangL. ChrismanW. NguyenL. AyanruohM. HooperI. BudunovaJ. GuitartM. BurnsX. Zhou

skin microbiomemicrobiomeexperimental dermatologyhealthy individualsdermatologyracial differences

Activation of Il1A/Irak1 Axis and Downstream Proinflammatory Signaling in Healthy Adult and Neonatal African American Skin. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Dimitry TrubetskoyPatrick GrudzienAnna KlopotLam TsoiBethany Perez-WhiteRoopal KunduIrina Budunova

downstream proinflammatoryinflammationoral biologycutaneous biologyimmunologydermatologyimmune responsesafrican american studieswound healing

Interferon Signaling Activation and Line1 Expression Under Influence of Anticancer Plant Secondary Metabolites. Preprints.org (2024)

Olga VlasovaIrina AntonovaKhamis MagomedovaAlena OsipovaPolina ShtompelAnna BorunovaTatyana ZabotinaGennady BelitskyIrina BudunovaAlbert JordanKirill KirsanovMarianna Yakubovskaya

gene expressionbiochemistrymolecular biologysystems biologycell signalingsecondary metabolitessignaling pathways

Synthesis and Anti-Cancer Activity of Novel Selective Glucocorticoid Receptor Agonists of Phenylethanolamine Series. (2024)

Ekaterina M. ZhidkovaLeyla R. TilovaTimur I. FetisovKirill I. KirsanovEvgeny P. KulikovAdel D. EnikeevIrina V. BudunovaGennady A. BadunMaria G. ChernyshevaValerii Z. ShirinianMarianna G. YakubovskayaEkaterina A. Lesovaya

tumor targetinganti-cancer agentsglucocorticoidsphenylethanolamine seriesmolecular cancerorganic chemistryfunctional modificationpharmaceuticsbiomolecular engineeringpharmacologymedicinal chemistryanti-cancer activityoncologyorganic synthesispharmacotherapydrug discoverymolecular biologytherapeutic efficacymedicinal research

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Irina V Budunova

Professor

Northwestern University

Affiliations

Feinberg School of Medicine

Department of Dermatology

Department of Urology

Irina V Budunova is currently serving as a Dermatology Professor at Northwestern University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Irina V Budunova

Northwestern University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

0625 Skin as a Potential Entry Point for Sars-Cov-2 Virus. Journal of Investigative Dermatology (2025)

viral pathogenesissars-cov-2virologyinfectious diseasesmedical virologypathogenesiscovid-19virus researchcommunicable diseasesvirus transmissionpotential entry pointdermatologygeneral virology

0703 Distinct Responses of 3D African American and White Non-Hispanic Skin Organoids to Key Pro-Inflammatory Cytokines. Journal of Investigative Dermatology (2025)

inflammationdermatological treatmentcutaneous biologyexperimental dermatologyimmunologydermatologyimmune responsesexperimental medicineclinical dermatology

0925 Redd1/Ddit4 Knockout Prevents Skin Atrophy in Aged Mice. Journal of Investigative Dermatology (2025)

knockout miceaged miceaging celldermatologyneurodegenerative diseases

Anticancer Plant Secondary Metabolites Evicting Linker Histone H1.2 From Chromatin Activate Type I Interferon Signaling. International Journal of Molecular Sciences (2025)

Olga VlasovaIrina AntonovaKhamis MagomedovaAlena OsipovaPolina ShtompelAnna BorunovaTatiana ZabotinaGennady BelitskyIrina BudunovaAlbert JordanKirill KirsanovMarianna Yakubovskaya

Il-1 Signaling Enrichment in Inflammatory Skin Disease Loci With Higher Risk Allele Frequencies in African Ancestry. Research Square (2025)

Skin Microbiota Differs Between Black and White Patients With Cutaneous T-Cell Lymphoma. Journal of the American Academy of Dermatology (2025)

533 Racial Differences in the Skin Microbiome of Cutaneous T-Cell Lymphoma Patients Are Not Present in That of Healthy Individuals. Journal of Investigative Dermatology (2024)

Y. PangL. ChrismanW. NguyenL. AyanruohM. HooperI. BudunovaJ. GuitartM. BurnsX. Zhou

skin microbiomemicrobiomeexperimental dermatologyhealthy individualsdermatologyracial differences

Activation of Il1A/Irak1 Axis and Downstream Proinflammatory Signaling in Healthy Adult and Neonatal African American Skin. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Dimitry TrubetskoyPatrick GrudzienAnna KlopotLam TsoiBethany Perez-WhiteRoopal KunduIrina Budunova

downstream proinflammatoryinflammationoral biologycutaneous biologyimmunologydermatologyimmune responsesafrican american studieswound healing

Interferon Signaling Activation and Line1 Expression Under Influence of Anticancer Plant Secondary Metabolites. Preprints.org (2024)

Olga VlasovaIrina AntonovaKhamis MagomedovaAlena OsipovaPolina ShtompelAnna BorunovaTatyana ZabotinaGennady BelitskyIrina BudunovaAlbert JordanKirill KirsanovMarianna Yakubovskaya

gene expressionbiochemistrymolecular biologysystems biologycell signalingsecondary metabolitessignaling pathways

Synthesis and Anti-Cancer Activity of Novel Selective Glucocorticoid Receptor Agonists of Phenylethanolamine Series. (2024)

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translational research

oncogene

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Vanderbilt University

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molecular cancer