Faculty

Institution

Unit

Venue

Hongyu Ruan

Assistant Professor of Psychiatry and Behavioral Sciences

Upstate Medical University

Affiliations

Norton College of Medicine

Department Of Anesthesiology

Department Of Psychiatry And Behavioral Sciences

Program Of Depression And Anxiety Disorders Research

Department Of Psychiatry

Department Of Psychiatry And Behavioural Neuroscience

Departments Of Psychiatry And Neuroscience

Division Of Forensic Psychiatry

Department Of Anesthesiology

Norton College Of Medicine

Psychiatry - Community Campus

Upstate Medical University

Hongyu Ruan is currently serving as an Anesthesiology Assistant Professor of Psychiatry and Behavioral Sciences at Upstate Medical University.

Honors

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Experiences

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Education

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Hongyu Ruan

Upstate Medical University

Assistant Professor of Psychiatry and Behavioral Sciences

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neuroscience molecular biology cell biology molecular cell biology genetics signal transduction cognitive neuroscience molecular neuroscience cellular biochemistry neuropsychopharmacology gene expression molecular and cellular biology cell signaling behavioral neuroscience protein function psychiatric genetics molecular neurobiology brain function longevity protein science biological psychiatry behavioural process cell regulation molecular regulation cellular neurobiology redox biology enzyme inhibition biochemical sciences behavioral disorders molecular psychiatry neuroscience of aging insect molecular biology avian biology developmental cognitive neuroscience cell death lifecycle model enzyme catalysis continual improvement process biocatalysis frontotemporal dementia neurodiversity inhibitory activity long non-coding rna working memory mutagenesis lifespan extension lifespan development small rna rna biology cell interactions neurodynamics gene regulation signaling pathways neurotransmission neurotransmitters intracellular trafficking gene function genetic basis allelic variant gene regulatory networks high-quality life extension ampa receptors social behavioral deficits prefrontal synaptic plasticity homeostatic synaptic plasticity botulinum neurotoxins neuron survival proteasome-independent polyubiquitin linkage prefrontal circuitry transcription factor pou3f2 cellular functions trim8 expression cylindromatosis drives akt-mtor signaling cocaine exposure facilitates synaptic potentiation adolescent health post-traumatic stress disorder psychological medicine schizophrenia behavioural genetics child psychology abnormal child psychology human genetics psychiatric research psychology psychiatric epidemiology psychological bulletin psychiatric care neurogenetics developmental psychopathology applied psychology substance use alcohol (drug) addiction neuropsychology substance use disorders mental health public health health psychology developmental psychology translational psychiatry psychopathology family medicine anxiety disorders behavioral sciences addictive behaviors clinical psychology emotional selfregulation pediatrics world psychiatry psychiatry addiction medicine addiction biology neurodevelopmental disorders jama psychiatry substance abuse affective disorders child development depression attention disorders

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Epigenetic Reader Phf21B Modulates Neurotransmission and Synaptic Plasticity-Related Genes in the Hippocampus, and Social Memory. The International Journal of Neuropsychopharmacology (2025)

neuropsychopharmacologystructural plasticityand social memoryneurogeneticsmemory studiesmolecular neurosciencepsychiatric geneticsbrain functionepigeneticscognitive scienceneuroscience

Usp48/Usp31 is a Nuclear Deubiquitinase That Potently Regulates Synapse Remodeling. bioRxiv (Cold Spring Harbor Laboratory) (2023)

protein functionmolecular neurosciencemolecular and cellular biologymolecular cell biologymolecular biologymolecular pathwayscellular biochemistrynuclear deubiquitinasebiochemistrycell biology

Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy Through Akt-Mtor Signaling. Molecular Psychiatry (2022)

signaling pathwayscell deathcellular physiologycytoskeletoncell regulationakt-mtor signalingcell signalingmolecular regulationmolecular cell biologycylindromatosis drivesmolecular biologysignal transductionautophagycellular biochemistrycell biology

The Epigenetic Reader Phf21B Modulates Murine Social Memory and Synaptic Plasticity–Related Genes. JCI Insight (2022)

Eunice W.M. ChinQi MaHongyu RuanCamille ChinAditya SomasundaramChunling ZhangChunyu LiuMartin D. LewisMelissa WhiteTracey L. SmithMalcolm BattersbyWei-Dong YaoXin-Yun LuWadih ArapJulio LicinioMa-Li Wong

cognitive neurosciencedevelopmental biologygenetic basisgeneticsmammalian biologygene functionsynaptic plasticity-related genesepigeneticsneuroscience

39. Chronic Stress Regulation of Spliceosome-Associated Protein Cwc22 Modulates Hippocampal Neuronal Structure and Function. European Neuropsychopharmacology (2021)

molecular neurosciencemolecular regulationmolecular neurobiologymolecular cell biologymolecular neurodegenerationchronic stress regulationcellular neurobiologyneuroscienceneuronscell biology

Loss of Mglur1-Ltd Following Cocaine Exposure Accumulates Ca 2+ -Permeable Ampa Receptors and Facilitates Synaptic Potentiation in the Prefrontal Cortex. Journal of Neurogenetics (2021)

physiologycognitive neuroscienceneuropsychopharmacologypharmacologyneurotransmissionneuropharmacologyfacilitates synaptic potentiationaddiction biologyneurotransmitterscocaine exposureprefrontal cortexneuroscienceneurophysiologyneurons

Transcription Factor Pou3F2 Regulates Trim8 Expression Contributing to Cellular Functions Implicated in Schizophrenia. Molecular Psychiatry (2020)

biological psychiatrycellular functionsschizophreniagene expressiontranscription factorsmolecular cell biologytranscription factor pou3f2molecular biologypsychiatric geneticstrim8 expressiongene regulationcell biology

The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy. Brain Research (2019)

protein functioncell signalingintracellular traffickingmolecular and cellular biologymolecular cell biologyubiquitin-editing enzyme a20molecular biologysignal transductionprotein sciencecellular biochemistrycell biology

Cocaine Promotes Coincidence Detection and Lowers Induction Threshold During Hebbian Associative Synaptic Potentiation in Prefrontal Cortex. Journal of Neuroscience (2017)

cognitive neuroscienceneuropsychopharmacologybehavioural processlowers induction thresholdaddictiondopaminebrain functionprefrontal cortexcognitive scienceneurosciencebehavioral neuroscience

Generation and Characterization of New Alleles of Quiver ( Qvr ) That Encodes an Extracellular Modulator of the Shaker Potassium Channel. Journal of Neurogenetics (2017)

Hongyu RuanAtsushi UedaXiaomin XingXuxuan WanBenjamin StrubSpencer MukaiKaan CertelDavid GreenKyle BelozerovWei-Dong YaoWayne JohnsonJim Jung-Ching LinArthur J. HillikerChun-Fang Wu

gene expressionelectrophysiologyextracellular modulatorcell regulationgene regulatory networksneurogeneticsgeneticsmolecular neurobiologyallelic variantmolecular biologysignal transductioncellular neurobiologyneuroscienceneuroanatomy

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Hongyu Ruan

Assistant Professor of Psychiatry and Behavioral Sciences

Upstate Medical University

Affiliations

Norton College of Medicine

Department Of Anesthesiology

Department Of Psychiatry And Behavioral Sciences

Program Of Depression And Anxiety Disorders Research

Department Of Psychiatry

Department Of Psychiatry And Behavioural Neuroscience

Departments Of Psychiatry And Neuroscience

Division Of Forensic Psychiatry

Department Of Anesthesiology

Norton College Of Medicine

Psychiatry - Community Campus

Upstate Medical University

Hongyu Ruan is currently serving as an Anesthesiology Assistant Professor of Psychiatry and Behavioral Sciences at Upstate Medical University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Hongyu Ruan

Upstate Medical University

Assistant Professor of Psychiatry and Behavioral Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Epigenetic Reader Phf21B Modulates Neurotransmission and Synaptic Plasticity-Related Genes in the Hippocampus, and Social Memory. The International Journal of Neuropsychopharmacology (2025)

neuropsychopharmacologystructural plasticityand social memoryneurogeneticsmemory studiesmolecular neurosciencepsychiatric geneticsbrain functionepigeneticscognitive scienceneuroscience

Usp48/Usp31 is a Nuclear Deubiquitinase That Potently Regulates Synapse Remodeling. bioRxiv (Cold Spring Harbor Laboratory) (2023)

protein functionmolecular neurosciencemolecular and cellular biologymolecular cell biologymolecular biologymolecular pathwayscellular biochemistrynuclear deubiquitinasebiochemistrycell biology

Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy Through Akt-Mtor Signaling. Molecular Psychiatry (2022)

The Epigenetic Reader Phf21B Modulates Murine Social Memory and Synaptic Plasticity–Related Genes. JCI Insight (2022)

cognitive neurosciencedevelopmental biologygenetic basisgeneticsmammalian biologygene functionsynaptic plasticity-related genesepigeneticsneuroscience

39. Chronic Stress Regulation of Spliceosome-Associated Protein Cwc22 Modulates Hippocampal Neuronal Structure and Function. European Neuropsychopharmacology (2021)

molecular neurosciencemolecular regulationmolecular neurobiologymolecular cell biologymolecular neurodegenerationchronic stress regulationcellular neurobiologyneuroscienceneuronscell biology

Loss of Mglur1-Ltd Following Cocaine Exposure Accumulates Ca 2+ -Permeable Ampa Receptors and Facilitates Synaptic Potentiation in the Prefrontal Cortex. Journal of Neurogenetics (2021)

Transcription Factor Pou3F2 Regulates Trim8 Expression Contributing to Cellular Functions Implicated in Schizophrenia. Molecular Psychiatry (2020)

The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy. Brain Research (2019)

Cocaine Promotes Coincidence Detection and Lowers Induction Threshold During Hebbian Associative Synaptic Potentiation in Prefrontal Cortex. Journal of Neuroscience (2017)

cognitive neuroscienceneuropsychopharmacologybehavioural processlowers induction thresholdaddictiondopaminebrain functionprefrontal cortexcognitive scienceneurosciencebehavioral neuroscience

Generation and Characterization of New Alleles of Quiver ( Qvr ) That Encodes an Extracellular Modulator of the Shaker Potassium Channel. Journal of Neurogenetics (2017)

Hongyu RuanAtsushi UedaXiaomin XingXuxuan WanBenjamin StrubSpencer MukaiKaan CertelDavid GreenKyle BelozerovWei-Dong YaoWayne JohnsonJim Jung-Ching LinArthur J. HillikerChun-Fang Wu

1
2
10 / page