Faculty

Institution

Unit

Venue

Hong Chen

Associate Professor FSHN Associate Professor Nutritional Sciences

UIUC

Affiliations

College of Agricultural, Consumer and Environmental Sciences

Department of Food Science and Human Nutrition

Food Science and Human Nutrition

Hong Chen is currently serving as a College Of Agricultural, Consumer And Environmental Sciences Associate Professor FSHN Associate Professor Nutritional Sciences at Uiuc.

Honors

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Experiences

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Education

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Hong Chen

UIUC

Associate Professor FSHN Associate Professor Nutritional Sciences

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cell biology cancer research molecular cancer tumor biology cancer cells metabolism oncogenes molecular nutrition nutrition colorectal cancer physiology oncology metabolic syndrome genetics cancer biology gene expression epigenetics molecular gastroenterology liver physiology radiation oncology obesity molecular cell biology obesity medicine cell metabolism nutritional biochemistry epigenetic changes metabolic regulation metabolic health dna methylation epigenomics cancer genetics cancer discovery molecular metabolism environmental epigenetics tumor suppressors molecular diagnostics transcription regulation molecular regulation chemoprevention strategies fatty liver disease amino acid deprivation lipid nutrition cell regulation gut barrier cell death cellular biochemistry antioxidants gene regulation cancer genomics microrna detection amino acid limitation cancer growth experimental nutrition gene expression profiling cellular immune responses immune checkpoint inhibitors cancer metastasis histone modifications epigenetic regulation lipid accumulation early life protein expression cell cycle anti-cancer agents polysaccharides small rna phytochemicals cancer risk wnt signaling soy protein isolate amino acid availability ziziphus jujuba cv transcription rate glutamate biosynthesis h19 gene expression low protein diet epigenetic modifications

Notable Scholarly Works

Notable Federal Grants

Collaborators

Gut Microbiota Dysbiosis in a Novel Mouse Model of Colitis Potentially Increases the Risk of Colorectal Cancer. AJP Gastrointestinal and Liver Physiology (2025)

Abrory A.C. PramanaGuanying Bianca XuSiyuan LiangErick Omar Garcia VazquezJacob M. AllenBrett Lomanwenyan meiYuan-Xiang PanHong Chen

molecular gastroenterologymicrobiologydss challengeinflammatory bowel diseasegastroenterologydigestive diseasesdysbiosismicrobiomegut microbiotaimmunologynovel mouse modelgut microbesmucosal immunologygut barrier

Modifying Microbial Risk for Colorectal Neoplasia- a Precision Nutrition Study of Magnesium Supplementation, Trpm7 Genotypes, and Gut Microbiome. Journal of Nutrition (2025)

Hong Chen

microbiologycolorectal cancerdigestive diseasesclinical nutritiondysbiosisprecision nutrition studymicrobiomenutritionmagnesium supplementationgut microbestrpm7 genotypeshealth sciences

Development of Nr0B2 as a Therapeutic Target for the Re-Education of Tumor Associated Myeloid Cells. Cancer Letters (2024)

Hashni Epa Vidana GamageSamuel T AlbrightAmanda J SmithRachel FarmerSayyed Hamed ShahoeiYu WangEmma C FinkElise JacquinErin WeisserRafael O BautistaMadeline A HennClaire P SchaneAdam T NelczykLiqian MaAnasuya Das GuptaShruti V BendreTiffany NguyenSrishti TiwariNatalia KrawczynskaSisi HeEvelyn TjoandaHong ChenMaria SverdlovPeter H GannRomain BoidotFrederique VegranSean W FanningLionel ApetohPaul J HergenrotherErik R Nelson

immunomodulationcancer immunotherapyimmune responsestumor biologycellular therapymolecular cancercell biologycancer cellsimmune checkpoint inhibitorsimmunotherapyoncogenescancer immunosurveillanceimmunologycholesterol homeostasisimmune checkpoint blockadebreast cancercellular immune responses

Nr0B2 Re-Educates Myeloid Immune Cells to Reduce Regulatory T Cell Expansion and Progression of Breast and Other Solid Tumors. Cancer Letters (2024)

Hashni Epa Vidana GamageSayyed Hamed ShahoeiYu WangElise JacquinErin WeisserRafael O. BautistaMadeline A. HennClaire P. SchaneAdam T. NelczykLiqian MaAnasuya Das GuptaShruti V. BendreTiffany NguyenSrishti TiwariEvelyn TjoandaNatalia KrawczynskaSisi HeSamuel T. AlbrightRachel FarmerAmanda J. SmithEmma C. FinkHong ChenMaria SverdlovPeter H. GannRomain BoidotFrederique VegranSean W. FanningPaul J. HergenrotherLionel ApetohErik R. Nelson

metastasiscancer immunotherapyimmune responsesmolecular cancercell biologycancer cellsimmune checkpoint inhibitorsimmunotherapyoncogenescancer immunosurveillanceimmunologyimmunoeditingimmune systemcholesterol metabolismbreast cancercellular immune responses

Increasing Dietary Nutrient Levels Modulates Colon Immune Adaptation and Alleviates Inflammation in the Epithelial Heterogeneous Nuclear Ribonucleoprotein I (Hnrnp I) Knockout Mice. The Journal of Nutritional Biochemistry (2023)

Guanying Bianca XuMingzhu CaiFatma Zehra KadayifciJuncen DongShasha ZhengWenyan MeiWen ZhaoYuan-Xiang PanHong Chen

molecular gastroenterologyimmune responsesinflammatory bowel diseasedigestive diseasesinflammationclinical nutritionknockout micenutritioncolon immune adaptationinflammatory diseasesimmunologymucosal immunologymolecular nutritionmouse modelgut barrierpathology

Re-Education of Myeloid Immune Cells to Reduce Regulatory T Cell Expansion and Impede Breast Cancer Progression. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Hashni Epa Vidana GamageSayyed Hamed ShahoeiSamuel T. AlbrightYu WangAmanda J. SmithRachel FarmerEmma C. FinkElise JacquinErin WeisserRafael O. BautistaMadeline A. HennClaire P. SchaneAdam T. NelczykLiqian MaAnasuya Das GuptaShruti V. BendreTiffany NguyenSrishti TiwariNatalia KrawczynskaSisi HeEvelyn TjoandaHong ChenMaria SverdlovPeter H. GannRomain BoidotFrederique VegranSean W. FanningLionel ApetohPaul J. HergenrotherErik R. Nelson

metastasisimmunomodulationcancer immunotherapyimmune responsescellular therapysmall molecule agonistscell biologycancer cellsimmune checkpoint inhibitorsimmunotherapyoncogenescancer immunosurveillanceimmunologycholesterol homeostasisbreast cancercellular immune responses

Single-Cell Rna Sequencing (Scrna-Seq) Identifies L1Cam as a Key Mediator Between Epithelial Tuft Cell and Innate Lymphoid Cell in the Colon of Hnrnp I Knockout Mice. Biomedicines (2023)

Guanying (Bianca) XuYuan-Xiang PanWenyan MeiHong Chen

molecular gastroenterologychronic inflammationimmune responsesinflammatory bowel diseasedigestive diseasesinflammationsingle-cell analysissevere inflammatory responsecell biologycancer cellssingle-cell rna sequencinginflammatory diseasestranscriptomeimmunologycell researchmucosal immunologyko micepathology

Aberrant Regenerating‐Islet Derived ( Reg ) Gene Expression is an Early Indicator of Colonic Dysplasia in Heterogeneous Nuclear Ribonucleoprotein ( Hnrnp I ) Knockout Mice. The FASEB Journal (2022)

Siyuan LiangGuanying XuAbrory A. PramanaHong ChenYuan‐Xiang Pan

molecular gastroenterologyimmune responsesinflammatory bowel diseasegastroenterologydigestive diseasesinflammationcolon dysplasiacell biologymolecular cell biologyearly indicatorinflammatory diseasesimmunologymucosal immunologygene expressiongut barrierpathology

Characterization of Procyanidin Extracts From Hawthorn (Crataegus Pinnatifida) in Human Colorectal Adenocarcinoma Cell Line Caco-2, Simulated Digestion, and Fermentation Identified Unique and Novel Prebiotic Properties. Food Research International (2022)

Xue HanQian ZhouZhe GaoGuanying Bianca XuHong ChenBimal ChitrakarYasai SunWen ZhaoXuan LinKaixuan ZhouZhisheng Zhang

novel prebiotic propertiesprobioticsnatural productsbioactive compoundsphytotherapy researchphytochemical analysisbiochemistrypharmacologyantioxidantsnatural product researchphytochemicalsprocyanidin extractsfood functionsimulated digestion

Enhancement of Dpp-IV Inhibitory Activity and the Capacity for Enabling Glp-1 Secretion Through Rada16-Assisted Molecular Designed Rapeseed Peptide Nanogels. Food & Function (2022)

Feiran XuBaocai XuHong ChenXingrong JuElvira Gonzalez de Mejia

peptide engineeringbiomolecular engineeringpeptide sciencebiochemistryglycobiologypharmacologybiomoleculespeptide therapeuticsnanogel peptidesprotein engineeringenzyme inhibitionstorage modulusoriginal oligopeptidespeptides

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Hong Chen

Associate Professor FSHN Associate Professor Nutritional Sciences

UIUC

Affiliations

College of Agricultural, Consumer and Environmental Sciences

Department of Food Science and Human Nutrition

Food Science and Human Nutrition

Hong Chen is currently serving as a College Of Agricultural, Consumer And Environmental Sciences Associate Professor FSHN Associate Professor Nutritional Sciences at Uiuc.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Hong Chen

UIUC

Associate Professor FSHN Associate Professor Nutritional Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Gut Microbiota Dysbiosis in a Novel Mouse Model of Colitis Potentially Increases the Risk of Colorectal Cancer. AJP Gastrointestinal and Liver Physiology (2025)

Abrory A.C. PramanaGuanying Bianca XuSiyuan LiangErick Omar Garcia VazquezJacob M. AllenBrett Lomanwenyan meiYuan-Xiang PanHong Chen

Modifying Microbial Risk for Colorectal Neoplasia- a Precision Nutrition Study of Magnesium Supplementation, Trpm7 Genotypes, and Gut Microbiome. Journal of Nutrition (2025)

Hong Chen

microbiologycolorectal cancerdigestive diseasesclinical nutritiondysbiosisprecision nutrition studymicrobiomenutritionmagnesium supplementationgut microbestrpm7 genotypeshealth sciences

Development of Nr0B2 as a Therapeutic Target for the Re-Education of Tumor Associated Myeloid Cells. Cancer Letters (2024)

Nr0B2 Re-Educates Myeloid Immune Cells to Reduce Regulatory T Cell Expansion and Progression of Breast and Other Solid Tumors. Cancer Letters (2024)

Guanying Bianca XuMingzhu CaiFatma Zehra KadayifciJuncen DongShasha ZhengWenyan MeiWen ZhaoYuan-Xiang PanHong Chen

Re-Education of Myeloid Immune Cells to Reduce Regulatory T Cell Expansion and Impede Breast Cancer Progression. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Single-Cell Rna Sequencing (Scrna-Seq) Identifies L1Cam as a Key Mediator Between Epithelial Tuft Cell and Innate Lymphoid Cell in the Colon of Hnrnp I Knockout Mice. Biomedicines (2023)

Guanying (Bianca) XuYuan-Xiang PanWenyan MeiHong Chen

Siyuan LiangGuanying XuAbrory A. PramanaHong ChenYuan‐Xiang Pan

Xue HanQian ZhouZhe GaoGuanying Bianca XuHong ChenBimal ChitrakarYasai SunWen ZhaoXuan LinKaixuan ZhouZhisheng Zhang

Enhancement of Dpp-IV Inhibitory Activity and the Capacity for Enabling Glp-1 Secretion Through Rada16-Assisted Molecular Designed Rapeseed Peptide Nanogels. Food & Function (2022)

Feiran XuBaocai XuHong ChenXingrong JuElvira Gonzalez de Mejia

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