Faculty

Institution

Unit

Venue

Hiroko Dodge

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Department Of Pediatrics

Oregon Center For Aging And Technology (Orcatech)

Department Of Pediatrics

Division Of Neurology

Oregon Health & Science University

Hiroko Dodge is a Senior Professor at Oregon Health & Science University. Her research focuses on cognitive impairment, Alzheimer’s disease, and the neuroscience of aging, with particular emphasis on early detection and intervention strategies. Recent work includes investigating oral nicotinamide riboside supplementation for cognitive decline, CSF proteomics in normal pressure hydrocephalus, and brain MRI signatures across sex and Alzheimer’s biomarkers. She has also advanced methodological innovations, such as synthetic control methods for n-of-1 trials and the SLIM method for optimizing fluid biomarker assessments in clinical trials. Her interdisciplinary collaborations span neurology, public health, and health services research.

Honors

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Experiences

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Education

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Hiroko Dodge

Oregon Health & Science University

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cognitive impairment alzheimer's disease neuroscience neurology dementia geriatrics neuroscience of aging public health health sciences ageing experimental gerontology neurodegenerative diseases older adults aging-associated diseases mild cognitive impairment later adulthood social gerontology neuropsychology geriatric medicine health technology geriatric neurology white matter elderly care vascular dementia geriatric assessment cognitive decline applied cognitive psychology molecular neurodegeneration clinical gerontology neuropsychological rehabilitation social isolation geriatric psychiatry brain health cognitive rehabilitation cerebral blood flow human-computer interaction population aging loneliness neuroimaging biomarkers neuropsychological functioning physiological measurements speech communication neurorehabilitation experimental medicine brain imaging disease assessment language disorders omega-3 fatty acids brain pathology cognitive function movement disorders neurolinguistics biogerontology brain function alzheimer disease neuropsychological test battery clinical neurology pathological gait gait analysis uniform data set regional studies fall prevention memory loss mental health monitoring disease progression depressive symptoms white matter hyperintensities nih toolbox memory studies health monitoring late life community-based study community-based cohort alzheimer disease centers gait speed advanced age

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Comprehensive Investigation of Machine Learning Practices in Predictive Modeling of Alzheimer’s Disease and Related Dementias Using Multisite Real-World Electronic Health Records. medRxiv (2025)

machine learning practicespredictive analyticsbiomedical informaticscomprehensive investigationhealth informaticshealth information scienceprediction modellingpredictive modelingdementiastatisticscognitive impairmentmachine learning researchdata sciencecomputational intelligencealzheimer's diseasedisease classificationmachine learning toolsmachine learning

AI-Conect: Designing Responsible-AI-Based Conversational Chatbots for Dementia Intervention. Innovation in Aging (2025)

assistive technologyconversational user interfacedementia interventionsocial roboticsartificial intelligenceintelligent computingconversation analysisintelligent user interfaceslanguagehuman robot interactionchatbots

Associations Between Plasma Biomarkers and Longitudinal Neuropsychiatric Symptoms Across the Cognitive Spectrum in Older Adults: Findings From the Massachusetts Alzheimer's Disease Research Center. Alzheimer s & Dementia (2025)

neurologyvascular dementiaplasma biomarkersaging-associated diseasesmassachusetts alzheimercognitive spectrumpsychiatric researchpsychiatrycognitive impairmentmolecular neurodegenerationneuroscience of agingalzheimer's diseasegeriatric neurologyneuroscienceneurodegenerative diseases

Augmented Risk Prediction for Alzheimer’s Onset From Electronic Health Records With Large Language Models. Innovation in Aging (2025)

risk predictionpredictive analyticsbiomedical informaticsalzheimer ’disease risk assessmenthealth informaticshealth information sciencestatisticsmachine learning researchdisease classificationdata sciencealzheimer's diseaselarge language models

Brain Mri Signatures Across Sex and Csf Alzheimer’s Disease Biomarkers. Brain Communications (2025)

You ChengYingnan HeKarthik GopinathBenjamin BillotJuan Eugenio IglesiasChao-Yi WuHiroko DodgeAnne-Marie WillsBecky CarlylePia KivisäkkBradley T HymanSteven E ArnoldSudeshna DasFrank TennigkeitAndrea PfeiferChristine VincenzettiFabien MoninGautam MaitraJoseph O'SullivanAlex TeligladasAna DiazChristophe BintenerCindy BirckDianne GoveJean GeorgesKatherine EllisStefanie PeulenEva DanasiGeorgios VlachosNicolaos ScarmeasAlexandre MencikCynthia NgHernan J PicardMats EricsonMatt GauntNicolas PourbaixRob LenzRodolphe EyraudRoss McGarrityVeronique ChauvetAla-Eddine AlloucheBéatrice Le BalangerBruno DuboisEdith BenmansourFrancis NyasseHicham FilaliIhsen YoussefLeslie AmeilMarion DuboisNabila LajaailNabila NyasseNadja YounsiPatrick Feukam TallaSouza BenadjaoudStephane LehericyTatiana Akake BeshelemuBelén Garcia AlonsoBet MolinaIan SherriffPedro PesiniPedro TiradoVirgina PérezAlan McNeillAlicia GibsonAndrew FoxBert OverduinChristine LeeDavid AllanDavid TaylorEmma McDonaldHarry PeakerKaren O'HanlonKaren ThorntonLorna HarperPamela BrankinRobert BryceRodrigo BarnesAna Belén CalladoAndreea RadoiAnnabella BetetaArcadi NavarroBeatriz BlascoCarolina HerreroCarolina MinguillonEider ArenazaEva NebotGema HuesaGemma Salvadó BlascoGloria OliverGonzalo Sánchez BenavidesGregory OpertoIva KnezevicJordi CamíJose Luis MolinuevoJuan Domingo GispertJulieta PeredaKarine FauriaLaia TenasMahnaz ShekariMaria Teresa Buongiorno

neurologycsf amyloiddisease biomarkersneuroimaging biomarkerssex differencesneuroimagingneuroradiologyneurochemical biomarkerscognitive impairmentmolecular neurodegenerationneuroscience of agingalzheimer's diseaseneuroscienceneurodegenerative diseases

Bridging Language Markers and Pathology: Correlations Between Digital Speech Measures and Surrogate Csf Biomarkers in Alzheimer’s Disease. bioRxiv (Cold Spring Harbor Laboratory) (2025)

language markersneurologyaging-associated diseasesfluency disordersalzheimer ’surrogate csf biomarkerslanguagealzheimer's diseasegeriatric neurologyneuroscience of agingneurodegenerative diseaseslanguage assessment

Changes in Conversational Pattern as a Clinical Trial Outcome Using the I‐Conect Data. Alzheimer s & Dementia (2025)

health communicationspeech communicationverbal interactionscommunication disordersconversation analysiscognitive communicationi‐conect dataconversational patternlanguagelanguage assessmentclinical trial outcomelinguisticspsycholinguistics

Cognitive and Alzheimer's Disease Biomarker Effects of Oral Nicotinamide Riboside (Nr) Supplementation in Older Adults With Subjective Cognitive Decline and Mild Cognitive Impairment. Alzheimer s & Dementia Translational Research & Clinical Interventions (2025)

neurologypharmacologyolder adultsaging-associated diseasessubjective cognitive declinecognitive impairmentmolecular neurodegenerationneuroscience of agingalzheimer's diseasegeriatric neurologyoral nicotinamide ribosideneuroscienceneurodegenerative diseases

Combined Impact of Plasma Phospho-Tau 217, Gfap and Nfl on Longitudinal Domain-Specific Cognitive Decline. Innovation in Aging (2025)

neurologyaging-associated diseasesbrain healthcognitive impairmentmolecular neurodegenerationneuroscience of agingplasma phospho-tau 217alzheimer's diseasecombined impactneuroscience

Combined Use of Plasma P‐Tau217, Nfl, and Gfap Predicts Domain‐Specific Cognitive Decline in Cognitively Unimpaired and MCI Individuals. Alzheimer s & Dementia (2025)

cognitive neuroscienceneuropsychologyaging-associated diseasesneuropsychological rehabilitationmci individualsdomain‐specific cognitive declineplasma p‐tau217brain healthcognitive impairmentmolecular neurodegenerationneuroscience of agingbrain functioncognitive scienceneuroscienceneurodegenerative diseases

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Hiroko Dodge

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Department Of Pediatrics

Oregon Center For Aging And Technology (Orcatech)

Department Of Pediatrics

Division Of Neurology

Oregon Health & Science University

Honors

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Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Hiroko Dodge

Oregon Health & Science University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

AI-Conect: Designing Responsible-AI-Based Conversational Chatbots for Dementia Intervention. Innovation in Aging (2025)

Augmented Risk Prediction for Alzheimer’s Onset From Electronic Health Records With Large Language Models. Innovation in Aging (2025)

Brain Mri Signatures Across Sex and Csf Alzheimer’s Disease Biomarkers. Brain Communications (2025)

Bridging Language Markers and Pathology: Correlations Between Digital Speech Measures and Surrogate Csf Biomarkers in Alzheimer’s Disease. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Changes in Conversational Pattern as a Clinical Trial Outcome Using the I‐Conect Data. Alzheimer s & Dementia (2025)

Combined Impact of Plasma Phospho-Tau 217, Gfap and Nfl on Longitudinal Domain-Specific Cognitive Decline. Innovation in Aging (2025)

neurologyaging-associated diseasesbrain healthcognitive impairmentmolecular neurodegenerationneuroscience of agingplasma phospho-tau 217alzheimer's diseasecombined impactneuroscience

Combined Use of Plasma P‐Tau217, Nfl, and Gfap Predicts Domain‐Specific Cognitive Decline in Cognitively Unimpaired and MCI Individuals. Alzheimer s & Dementia (2025)

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