Faculty

Institution

Unit

Venue

Ahlke Heydemann

Associate Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

Ahlke Heydemann is currently serving as a College Of Medicine Associate Professor at University of Illinois Chicago.

Honors

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Experiences

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Education

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Ahlke Heydemann

University of Illinois Chicago

Associate Professor

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muscular dystrophies cell biology regenerative medicine physiology genetics neuroscience cellular therapy clinical research medicinal research gene expression stem cell research cell therapy mammalian biology skeletal muscle cardiology clinical transplantation stem-cell therapy muscle function stem cells cell transplantation cellular physiology applied physiology duchenne muscular dystrophy vascular biology animal physiology hematology tissue engineering molecular cell biology clinical investigation cardiovascular research liver physiology stem cell transplantation clinical medicine cell research clinical physiology human dystrophin molecular physiology molecular regulation cardiomyopathy novel therapies biological therapies musculoskeletal research transplantation medicine medical genetics cardiac muscle knockout mice protein expression cell regulation gene regulation human physiology cell culture treatment and prevention treatment effects cell-matrix interactions biomedical modeling genetic basis biomedical research tissue transplantation clinical immunology laboratory immunology mammalian physiology clinical evidence novel transcription factor mdx mouse model systemic-intraosseous administration sarcolemmal repair hematopoietic stem cells aortic aneurysm dystrophin-sarcoglycan complex skeletal myopathy sarcoglycan-deficient cardiomyopathy cardiomyocyte degeneration brn4 gene product inner ear muscle plasma membrane muscle dysfunction medicine neuromuscular medicine myositis

Notable Scholarly Works

Notable Federal Grants

Collaborators

36. Long-Term Safety and Efficacy of Dt-Dec01 Therapy in Duchenne Muscular Dystrophy Patients at 24-Month Following Systemic Intraosseous Transplantation. Transplantation (2025)

clinical researchtranslational medicinemedicineclinical transplantationsystemic intraosseous transplantationmuscular dystrophiesorthopaedic surgerytransplant surgerydt-dec01 therapylong-term safetyneuromuscular medicinetransplantation medicinetranslational researchtransplantation proceeding

Amelioration of Morphological Pathology in Cardiac, Respiratory, and Skeletal Muscles Following Intraosseous Administration of Human Dystrophin Expressing Chimeric (Dec) Cells in Duchenne Muscular Dystrophy Model. Biomedicines (2024)

Maria SiemionowKatarzyna BudzynskaKristina ZalantsPaulina LangaSonia BrodowskaKrzysztof SiemionowAhlke Heydemann

medicinecell biologymorphological pathologybiomedical researchmuscle functionpharmacologygene expressionbiomechanicshuman dystrophincellular therapytreatment effectsmuscular dystrophiesintraosseous administrationtissue engineeringapplied physiologyvascular biologymedicinal researchmorphology (biology)tissue physiologycellular physiologycardiac muscle

A Brief Review of Duchenne Muscular Dystrophy Treatment Options, With an Emphasis on Two Novel Strategies. Biomedicines (2023)

Ahlke HeydemannMaria Siemionow

medicineoncologymuscular dystrophiesstrategic studiesnovel therapiescell biologybenchmark studiesneurosciencebrief reviewregenerative medicinecontinual improvement processclinical medicinemedicinal researchnovel strategiestreatment options

Assessment of Motor Unit Potentials Duration as the Biomarker of Dt-Dec01 Cell Therapy Efficacy in Duchenne Muscular Dystrophy Patients Up to 12 Months After Systemic–Intraosseous Administration. Archivum Immunologiae et Therapiae Experimentalis (2023)

Adam NiezgodaGrzegorz BiegańskiJacek WachowiakJarosław CzarnotaKrzysztof SiemionowAhlke HeydemannAnna ZiemieckaMaria H. SikorskaKatarzyna BożykMaria Siemionow

clinical evidencemusculoskeletal disorderslaboratory immunologycellular therapymuscular dystrophiesclinical immunologyrehabilitationphysical therapyapplied physiologysystemic-intraosseous administrationimmunologyimmunity (medicine)physiologymedicinal researchinflammationcell therapyregenerative medicineclinical rheumatologytreatment development

Dystrophin Expressing Chimeric (Dec) Cell Therapy for Duchenne Muscular Dystrophy: A First-In-Human Study With Minimum 6 Months Follow-Up. Stem Cell Reviews and Reports (2023)

Ahlke HeydemannGrzegorz BieganskiJacek WachowiakJarosław CzarnotaAdam NiezgodaKrzysztof SiemionowAnna ZiemieckaMaria H. SikorskaKatarzyna BozykStefan G. TulliusMaria Siemionow

personalized medicinecell biologycell transplantationdevelopmental biologystem cell researchcellular therapymuscular dystrophiesimmunotherapystem cell transplantationduchenne muscular dystrophypain therapynovel therapiesimmunologycell researchstem-cell therapymedicinal researchcell therapystem cellsfirst-in-human studyclinical research

Safety and Efficacy of Dt-Dec01 Therapy in Duchenne Muscular Dystrophy Patients: A 12 - Month Follow-Up Study After Systemic Intraosseous Administration. Stem Cell Reviews and Reports (2023)

Maria SiemionowGrzegorz BiegańskiAdam NiezgodaJacek WachowiakJarosław CzarnotaKrzysztof SiemionowAnna ZiemieckaMaria H. SikorskaKatarzyna BożykAhlke Heydemann

clinical evidenceneurosciencepharmacologystem cell researchcellular therapymuscular dystrophiescohort studiestreatment and preventionstem cell transplantationneurologyclinical transplantationmonth follow-up studyvascular biologystem-cell therapymedicinal researchsystemic intraosseous administrationstem cellsregenerative medicineoutcomes researchclinical research

The Mrl Mitochondrial Genome Decreases Murine Muscular Dystrophy Severity. Muscles (2023)

Jenan Holley-CuthrellAqsa IqbalAhlke Heydemann

geneticshuman geneticsmuscular dystrophiesmedical geneticsphysiologymolecular biology

CORRECTION: Long-Term Protective Effect of Human Dystrophin Expressing Chimeric (Dec) Cell Therapy on Amelioration of Function of Cardiac, Respiratory and Skeletal Muscles in Duchenne Muscular Dystrophy. Stem Cell Reviews and Reports (2022)

Maria SiemionowPaulina LangaSonia BrodowskaKatarzyna KozlowskaKristina ZalantsKatarzyna BudzynskaAhlke Heydemann

personalized medicineskeletal musclecell biologymusculoskeletal researchpharmacologyhuman dystrophinstem cell researchcellular therapymuscular dystrophiesduchenne muscular dystrophydegenerative diseaseclinical researchapplied physiologyimmunologycell researchstem-cell therapymedicinal researchcell therapystem cellsregenerative medicinelong-term protective effect

Long-Term Biodistribution and Safety of Human Dystrophin Expressing Chimeric Cell Therapy After Systemic-Intraosseous Administration to Duchenne Muscular Dystrophy Model. Archivum Immunologiae et Therapiae Experimentalis (2022)

Maria SiemionowSonia BrodowskaPaulina LangaKristina ZalantsKatarzyna KozlowskaWictoria Grau-KazmierczakAhlke Heydemann

cancer immunotherapylong-term biodistributionpharmacologymammalian biologylaboratory immunologyhuman dystrophincellular therapymuscular dystrophiesimmunotherapyclinical immunologyclinical transplantationsystemic-intraosseous administrationimmunologymedicinal researchcell therapymolecular evidencechimeric cell therapydermatologygenetic basisregenerative medicinemuscular dystrophy modelclinical researchpharmacotherapy

Human Dystrophin Expressing Chimeric (Dec) Cell Therapy Ameliorates Cardiac, Respiratory, and Skeletal Muscle's Function in Duchenne Muscular Dystrophy. Stem Cells Translational Medicine (2021)

Maria SiemionowPaulina LangaMichal HarasymczukJoanna CwykielMagdalena SielewiczJaroslaw SmieszekAhlke Heydemann

medicineskeletal musclecell biologymuscle functionmusculoskeletal researchgene expressionhuman dystrophinstem cell researchcellular therapymuscular dystrophiesduchenne muscular dystrophytranslational medicineapplied physiologyimmunologystem-cell therapymedicinal researchcell therapyregenerative medicinetranslational researchcellular physiology

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Ahlke Heydemann

Associate Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

Ahlke Heydemann is currently serving as a College Of Medicine Associate Professor at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ahlke Heydemann

University of Illinois Chicago

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

36. Long-Term Safety and Efficacy of Dt-Dec01 Therapy in Duchenne Muscular Dystrophy Patients at 24-Month Following Systemic Intraosseous Transplantation. Transplantation (2025)

Maria SiemionowKatarzyna BudzynskaKristina ZalantsPaulina LangaSonia BrodowskaKrzysztof SiemionowAhlke Heydemann

A Brief Review of Duchenne Muscular Dystrophy Treatment Options, With an Emphasis on Two Novel Strategies. Biomedicines (2023)

Ahlke HeydemannMaria Siemionow

Adam NiezgodaGrzegorz BiegańskiJacek WachowiakJarosław CzarnotaKrzysztof SiemionowAhlke HeydemannAnna ZiemieckaMaria H. SikorskaKatarzyna BożykMaria Siemionow

Dystrophin Expressing Chimeric (Dec) Cell Therapy for Duchenne Muscular Dystrophy: A First-In-Human Study With Minimum 6 Months Follow-Up. Stem Cell Reviews and Reports (2023)

Ahlke HeydemannGrzegorz BieganskiJacek WachowiakJarosław CzarnotaAdam NiezgodaKrzysztof SiemionowAnna ZiemieckaMaria H. SikorskaKatarzyna BozykStefan G. TulliusMaria Siemionow

Safety and Efficacy of Dt-Dec01 Therapy in Duchenne Muscular Dystrophy Patients: A 12 - Month Follow-Up Study After Systemic Intraosseous Administration. Stem Cell Reviews and Reports (2023)

Maria SiemionowGrzegorz BiegańskiAdam NiezgodaJacek WachowiakJarosław CzarnotaKrzysztof SiemionowAnna ZiemieckaMaria H. SikorskaKatarzyna BożykAhlke Heydemann

The Mrl Mitochondrial Genome Decreases Murine Muscular Dystrophy Severity. Muscles (2023)

Jenan Holley-CuthrellAqsa IqbalAhlke Heydemann

geneticshuman geneticsmuscular dystrophiesmedical geneticsphysiologymolecular biology

Maria SiemionowPaulina LangaSonia BrodowskaKatarzyna KozlowskaKristina ZalantsKatarzyna BudzynskaAhlke Heydemann

Maria SiemionowSonia BrodowskaPaulina LangaKristina ZalantsKatarzyna KozlowskaWictoria Grau-KazmierczakAhlke Heydemann

Human Dystrophin Expressing Chimeric (Dec) Cell Therapy Ameliorates Cardiac, Respiratory, and Skeletal Muscle's Function in Duchenne Muscular Dystrophy. Stem Cells Translational Medicine (2021)

Maria SiemionowPaulina LangaMichal HarasymczukJoanna CwykielMagdalena SielewiczJaroslaw SmieszekAhlke Heydemann

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Similar Faculty Members

Bjorn C. Knollmann

Institution

Vanderbilt University

electrophysiological evaluation

cardiovascular disease

Kanneboyina Nagaraju

Institution

Binghamton University

drug development

immunologic disease

Kenneth Margulies

Institution

University of Pennsylvania

cardiovascular toxicity

medicine

Elizabeth M McNally

Institution

Northwestern University

cardiology

genetics

Jan Nolta

Institution

University of California, Davis

stem cell

mesenchymal stem cells

Daniel Bernstein

Institution

Stanford University

pediatrics

cardiovascular disease

Jianyi Zhang

Institution

University of Alabama at Birmingham

cardiology

regenerative medicine

Stephen D. Nimer

Institution

University of Miami

molecular biology

haematopoiesis

Dongsheng Duan

Institution

University of Missouri

virus research

virology

Kevin Campbell

Institution

University of Iowa

neuroscience

membrane biology