Faculty

Institution

Unit

Venue

Haodi Wu

Assistant Professor of Medicine

University of Pittsburgh

Affiliations

Medicine

Interdisciplinary Biomedical Graduate Program

Haodi Wu is currently serving as an Interdisciplinary Biomedical Graduate Program Assistant Professor of Medicine at University of Pittsburgh.

Honors

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Experiences

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Education

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Haodi Wu

University of Pittsburgh

Assistant Professor of Medicine

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cardiology stem cell research cell biology regenerative medicine genetics stem cells cardiovascular research molecular biology cardiomyopathy induced pluripotent stem cells cell transplantation vascular biology biomedical engineering human genetics medicinal research stem-cell therapy stem cell transplantation mammalian biology tissue engineering gene expression cellular physiology in vivo systems cellular therapy genome biology translational medicine cellular differentiation protein science biomedical modeling cell research experimental medicine medical genetics biomedical imaging liver physiology translational bioinformatics transcriptomics technology cardiovascular physiology angiogenesis rna biology biomedical technologies stem cell mobilization crispr embryonic stem cells material research scientific data single-cell analysis cancer genetics applied genetics transcription regulation gene editing scientific visualization cardiac muscle cell regulation cancer biology brugada syndrome cancer treatment herbal medicine high-throughput screening cell interactions cell-matrix interactions cell proliferation omics integration doxorubicin-induced cardiotoxicity breast cancer patients low-impedance microelectrode arrays drug-induced arrhythmia cell-cell contact wnt activation single-cell phenotype neuronal tissue subcellular voltage dynamics two-photon imaging epigenetic regulation ipsc model b-adrenergic signaling qt phenotype drug testing aging cell heart failure physiology cardiac aging experimental gerontology cardiac dysfunction

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Allele-Specific Control of Rodent and Human Lncrna Kmt2E-As1 Promotes Hypoxic Endothelial Pathology in Pulmonary Hypertension. Science Translational Medicine (2024)

Yi-Yin TaiQiujun YuYing TangWei SunNeil J. KellySatoshi OkawaJingsi ZhaoTae-Hwi Schwantes-AnCaroline LacouxStephanie TorrinoYassmin Al AarajWadih El KhouryVinny NegiMingjun LiuCatherine G. CoreyFrances BelmonteSara O. VargasBrian SchwartzBal BhatB. Nelson ChauJason H. KarnesTaijyu SatohRobert J. BarndtHaodi WuVictoria N. ParikhJianrong WangYingze ZhangDennis McNamaraGang LiGil SpeyerBing WangSruti ShivaBrett KaufmanSeungchan KimDelphine GomezBernard MariMichael H. ChoAdel BoueizMichael W. PauciuloLaura SouthgateRichard C. TrembathOlivier SitbonMarc HumbertStefan GrafNicholas W. MorrellChristopher J. RhodesMartin R. WilkinsMehdi NouraieWilliam C. NicholsAnkit A. DesaiThomas BerteroStephen Y. Chan

vascular biologytumor biologyanimal physiologyliver physiologyphysiologyendothelial pathologytranslational medicineimmunologyrespiratory medicineendothelial dysfunctionmembrane biologypulmonary hypertensionclinical researchhuman geneticsmammalian biologyallele-specific controlgeneticsmammalian physiology

Dhcr7 Deficiency Promotes 7β-Hydroxycholesterol Accumulation and Endothelial Apoptosis in Pulmonary Hypertension. (2024)

R. RaoH.-J.J. KimS. JiangY.-Y. TaiB. WangY. TangW. El KhouryA. KirillovaY. Al AarajA.M. WatsonA.X. SharmaJ. McDonaldH. WuK. FrancisS. Ramachandra RaoS.J. FlieslerT. BerteroW. SunL.D. HarveyS.Y. Chan

cardiovascular diseaseinflammationvascular biologyclinical lipidologycardiovascular researchliver physiologyendothelial apoptosistreatment and preventionimmunologymolecular medicinemedicinal researchpulmonary hypertensionpharmacologyrenal pathophysiologyendocrinologylipid disordershealth sciences

Genetic Regulation and Targeted Reversal of Lysosomal Dysfunction and Inflammatory Sterol Metabolism in Pulmonary Arterial Hypertension. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Lloyd D HarveyMona AlotaibiHee-Jung Janice KimYi-Yin TaiYing TangWei SunWadih El KhouryChen-Shan C WoodcockYassmin Al AarajClaudette M St. CroixDonna B StolzJiyoung LeeMary Hongying ChengTae-Hwi Schwantes-AnAnkit A DesaiMichael W PauciuloWilliam C NicholsAmy WebbRobert LafyatisMehdi NouraieHaodi WuJeffrey G McDonaldCaroline ChauvetSusan ChengIvet BaharThomas BerteroRaymond L BenzaMohit JainStephen Y Chan

cardiologygenetic regulationrespiratory medicinepulmonary arterial hypertensionlysosomal dysfunctiongeneticsinflammatory sterol metabolism

Mitigation of Stress-Induced Structural Remodeling and Functional Deficiency in Ipsc-Cms With Pln R9C Mutation by Promoting Autophagy. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Qi YuRobert J BarndtYawei ShenKarim SallamYing TangStephen Y. ChanJoseph C. WuQing LiuHaodi Wu

functional deficiencyneurosciencemolecular geneticsautophagyhost geneticshuman geneticsstress-induced structural remodelinggeneticsgenomicsmolecular biologygene expressiongenome instabilitymitophagystructural biologygenome biologyprotein geneticsprotein sciencemolecular physiologygene functionmammalian biology

Abstract 15579: Stem Cell Modeling of a Candidate Genetic Variant in a Family With Complex Inherited Cardiomyopathy. Circulation (2023)

Anna KirillovaSiyi JiangYassmin Al AarajChloe ReuterYunshan YueRashmi RaoMichael CreagerRobert BarndtHaodi WuStuart ScottSatoshi OkawaVictoria N ParikhStephen Y Chan

mendelian inheritancestem cell modelingcardiologycandidate genetic variantcardiomyopathyhuman geneticsfamily medicinepopulation geneticsmedical geneticsgenetics

Abstract 162: Multiancestry Gwas and Functional Genomics Analysis of Hnf1A Locus to Define Novel Pathogenic Mechanism for Ischemic Stroke. Arteriosclerosis Thrombosis and Vascular Biology (2023)

Harsh HiwaseYunshan YueEric K HoffmanHaodi WuRobert J BarndtStephen Y ChanHyacinth I. HyacinthWei Sun

cardiovascular diseasepathologymultiancestry gwasischemic strokevascular biologyvascular diseaseatherosclerosishematologycerebrovascular diseasearterial diseasehealth scienceshealth policycardiologyangiologyrespiratory medicinethrombosispathway analysisstrokegenome biologyfunctional genomics analysiscardiovascular researchnovel pathogenic mechanism

Ectopic Expression of Sars-Cov-2 S and Orf-9B Proteins Alters Metabolic Profiles and Impairs Contractile Function in Cardiomyocytes. Frontiers in Cell and Developmental Biology (2023)

Peng ZhangYu LiuChunfeng LiLindsay D. StinePei-Hui WangMatthew W. TurnbullHaodi WuQing Liu

molecular and cellular biologyliver physiologytissue developmentdevelopmental biologycell and molecular biologyvascular biologycell biologydevelopmental sciencemolecular biologygene expressioncardiovascular physiologycardiologyprotein functioncellular physiologyectopic expressioncell regulationsars-cov-2molecular cell biologydevelopmental genetics

Long Non-Coding Rna Lhx1-Dt Regulates Cardiomyocyte Differentiation Through H2A.Z-Mediated Lhx1 Transcriptional Activation. iScience (2023)

Qi YuBenzhi CaiYong ZhangJuan XuDongping LiuXiyang ZhangZhenbo HanYingying MaLei JiaoManyu GongXuewen YangYanying WangHaodong LiLihua SunYu BianFan YangLina XuanHaodi WuBaofeng YangYing Zhang

cardiologylong non-coding rnacell signalingcell biologysignaling pathwaystranscription (biology)molecular biologytranscription regulationsignal transductiongene expressioncell regulationrna biologygenetics

Abstract 10096: Genetic Control of Lysosomal Dysfunction Reprograms Sterol Metabolism in Pulmonary Arterial Hypertension. Circulation (2022)

Lloyd D HarveyHee-Jung J KimMona AlotaibiYi-Yin TaiYing TangSanya ArshadWei SunHaodi WuJingsi ZhaoAnna KirillovaChen-shan J WoodcockAdam HandenYassmin Al AarajMiranda K CulleyNeha HafeezAnnie WatsonCallen WallaceHaodi WuMara G SullivanClaudette M St. CroixDonna StolzGang LiChase CorleyJeffrey G McDonaldMehdi NouraieTae-Hwi Schwantes-AnAnkit A DesaiMichael PauciuloBill NicholsRobert LafyatisRaymond L BenzaThomas BerteroMohit JainStephen Y Chan

cardiologynephrologyphysiologyepigeneticsrespiratory medicinegene regulationmolecular geneticsgenetic controlpulmonary arterial hypertensionmolecular biologyhuman geneticsmedical geneticsgenetics

A Red Fluorescent Protein With Improved Monomericity Enables Ratiometric Voltage Imaging With Asap3. Scientific Reports (2022)

Benjamin B. KimHaodi WuYukun A. HaoMichael PanMariya ChavarhaYufeng ZhaoMichael WestbergFrançois St-PierreJoseph C. WuMichael Z. Lin

biophysicsbiological imagingred fluorescent proteinneurosciencemolecular imagingmolecular biologyscientific dataneuroimagingmammalian biologyfluorescencescientific visualization

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Haodi Wu

Assistant Professor of Medicine

University of Pittsburgh

Affiliations

Medicine

Interdisciplinary Biomedical Graduate Program

Haodi Wu is currently serving as an Interdisciplinary Biomedical Graduate Program Assistant Professor of Medicine at University of Pittsburgh.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Haodi Wu

University of Pittsburgh

Assistant Professor of Medicine

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Allele-Specific Control of Rodent and Human Lncrna Kmt2E-As1 Promotes Hypoxic Endothelial Pathology in Pulmonary Hypertension. Science Translational Medicine (2024)

Dhcr7 Deficiency Promotes 7β-Hydroxycholesterol Accumulation and Endothelial Apoptosis in Pulmonary Hypertension. (2024)

R. RaoH.-J.J. KimS. JiangY.-Y. TaiB. WangY. TangW. El KhouryA. KirillovaY. Al AarajA.M. WatsonA.X. SharmaJ. McDonaldH. WuK. FrancisS. Ramachandra RaoS.J. FlieslerT. BerteroW. SunL.D. HarveyS.Y. Chan

Genetic Regulation and Targeted Reversal of Lysosomal Dysfunction and Inflammatory Sterol Metabolism in Pulmonary Arterial Hypertension. bioRxiv (Cold Spring Harbor Laboratory) (2024)

cardiologygenetic regulationrespiratory medicinepulmonary arterial hypertensionlysosomal dysfunctiongeneticsinflammatory sterol metabolism

Mitigation of Stress-Induced Structural Remodeling and Functional Deficiency in Ipsc-Cms With Pln R9C Mutation by Promoting Autophagy. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Qi YuRobert J BarndtYawei ShenKarim SallamYing TangStephen Y. ChanJoseph C. WuQing LiuHaodi Wu

Abstract 15579: Stem Cell Modeling of a Candidate Genetic Variant in a Family With Complex Inherited Cardiomyopathy. Circulation (2023)

Anna KirillovaSiyi JiangYassmin Al AarajChloe ReuterYunshan YueRashmi RaoMichael CreagerRobert BarndtHaodi WuStuart ScottSatoshi OkawaVictoria N ParikhStephen Y Chan

mendelian inheritancestem cell modelingcardiologycandidate genetic variantcardiomyopathyhuman geneticsfamily medicinepopulation geneticsmedical geneticsgenetics

Abstract 162: Multiancestry Gwas and Functional Genomics Analysis of Hnf1A Locus to Define Novel Pathogenic Mechanism for Ischemic Stroke. Arteriosclerosis Thrombosis and Vascular Biology (2023)

Harsh HiwaseYunshan YueEric K HoffmanHaodi WuRobert J BarndtStephen Y ChanHyacinth I. HyacinthWei Sun

Ectopic Expression of Sars-Cov-2 S and Orf-9B Proteins Alters Metabolic Profiles and Impairs Contractile Function in Cardiomyocytes. Frontiers in Cell and Developmental Biology (2023)

Peng ZhangYu LiuChunfeng LiLindsay D. StinePei-Hui WangMatthew W. TurnbullHaodi WuQing Liu

Long Non-Coding Rna Lhx1-Dt Regulates Cardiomyocyte Differentiation Through H2A.Z-Mediated Lhx1 Transcriptional Activation. iScience (2023)

Qi YuBenzhi CaiYong ZhangJuan XuDongping LiuXiyang ZhangZhenbo HanYingying MaLei JiaoManyu GongXuewen YangYanying WangHaodong LiLihua SunYu BianFan YangLina XuanHaodi WuBaofeng YangYing Zhang

Abstract 10096: Genetic Control of Lysosomal Dysfunction Reprograms Sterol Metabolism in Pulmonary Arterial Hypertension. Circulation (2022)

cardiologynephrologyphysiologyepigeneticsrespiratory medicinegene regulationmolecular geneticsgenetic controlpulmonary arterial hypertensionmolecular biologyhuman geneticsmedical geneticsgenetics

A Red Fluorescent Protein With Improved Monomericity Enables Ratiometric Voltage Imaging With Asap3. Scientific Reports (2022)

Benjamin B. KimHaodi WuYukun A. HaoMichael PanMariya ChavarhaYufeng ZhaoMichael WestbergFrançois St-PierreJoseph C. WuMichael Z. Lin

biophysicsbiological imagingred fluorescent proteinneurosciencemolecular imagingmolecular biologyscientific dataneuroimagingmammalian biologyfluorescencescientific visualization

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7
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