Hampartsoum Barsoumian

Hampartsoum Barsoumian is a Senior Professor at The University of Texas MD Anderson Cancer Center. His research focuses on radiation oncology, cancer immunotherapy, and immunology, with a specific emphasis on combining radiation therapy with immune checkpoint inhibitors for lung cancer and metastatic melanoma. His recent work has uncovered mechanisms by which cancer cells evade ferroptosis induced by immune cells via fatty acid binding proteins, and he has investigated the synergistic effects of low-dose radiation with adoptive cell therapy and antisense oligonucleotide inhibition of STAT6 and MER proto-oncogene tyrosine kinase to enhance systemic antitumor responses. He has also compared proton versus photon immunoradiotherapy, demonstrating superior antitumor immunity amplified by the nanoradioenhancer NBTXR3.