Faculty

Institution

Unit

Venue

Mark T. Hamann

Professor Charles and Carol Cooper/SmartState Endowed Chair of Drug Discovery and Biomedical Sciences

Medical University of South Carolina

Affiliations

College of Pharmacy

Mark T. Hamann is currently serving as a College Of Pharmacy Professor Charles and Carol Cooper/SmartState Endowed Chair of Drug Discovery and Biomedical Sciences at Medical University of South Carolina.

Honors

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Experiences

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Education

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Mark T. Hamann

Medical University of South Carolina

Professor Charles and Carol Cooper/SmartState Endowed Chair of Drug Discovery and Biomedical Sciences

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pharmacology natural products natural product research biochemistry bioactive compounds medicinal chemistry marine drug microbiology marine biology drug discovery chemistry phytochemical analysis marine biotechnology phytochemistry medicinal research natural product synthesis pharmaceutical chemistry antimicrobial agents botany marine chemistry enzyme inhibition phytotherapy research marine biota phytochemicals organic chemistry therapeutic targets secondary metabolites natural product biosynthesis antimicrobial compounds antiparasitic agent applied microbiology phytopharmacology environmental microbiology marine natural products plant science clinical microbiology antioxidants anti-cancer agents pharmaceutical sciences marine pollution antiviral drug development peptide science antiviral drugs manzamine alkaloids biochemical sciences inhibitory activity synthetic chemistry antiviral compounds antifungal agents drug development active ingredient marine ecology phycology biocatalysis antiviral therapy cancer treatment marine genomics pharmaceutical research absolute configuration marine pharmacology chemical composition marine organisms biological evaluation manzamine analogues key site fine chemicals molecular virology order verongida cytotoxic activity antiviral activities tropical parasitic diseases deep-water alaskan sponge antimalarial activity american sycamore therapeutic potential structure-activity relationship microbial consortium remote regions infectious diseases microbiome harmful microalgae

Notable Scholarly Works

Notable Federal Grants

Collaborators

Evaluation of Marine Natural Products for Neuritogenesis in Murine Primary Cortical Cultures (Abstract Id: 160003). Journal of Pharmacology and Experimental Therapeutics (2025)

aquaculturemariculturenatural productsembryologyabstract idmarine natural productsdevelopmental biologybiologymarine drugmarine biologydevelopmental neurobiologymarine biotechnology

Exploring the Therapeutic Potential of Mitragynine and Corynoxeine: Kratom-Derived Indole and Oxindole Alkaloids for Pain Management. Pharmaceuticals (2025)

Ahmed S. AlfordHope L. MorenoMenny M. BenjaminCody F. DickinsonMark T. Hamann

pharmaceutical scienceskratom-derived indoleoxindole alkaloidstherapeutic potentialpharmacologypain therapypain medicinepain management

Manzamine a: A Promising Marine-Derived Cancer Therapeutic for Multi-Targeted Interactions With E2F8, Six1, Ar, Gsk-3β, and V-Atpase - a Systematic Review. European Journal of Pharmacology (2025)

Mohammad Amir MishanYeun-Mun ChooJeffery WinklerMark T HamannDev Karan

anti-cancer agentsbioactive compoundscancer discoverypharmacologytherapeutic targetspromising marine-derived cancerclinical pharmacologysystematic reviewtumor biologymarine drugdrug discoverypharmacotherapycancer treatmentmedicinal researchmarine biologymarine biotechnologytumor targetingmulti-targeted interactionsbiomolecular engineering

Marine Metabolites for the Sustainable and Renewable Production of Key Platform Chemicals. Processes (2025)

marine metabolitesbiofuelsgreen chemistrychemical oceanographychemical engineeringenvironmental chemistrykey platform chemicalssustainable chemistryenvironmental engineeringmarine drugplatform chemicalmarine biotechnologyrenewable productionsustainable synthesis

Methylglyoxal Mutagenizes Single-Stranded Dna via Rev1-Associated Slippage and Mispairing. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Natalie SainiSriram VijayraghavanAlessandra RuggieroSamuel BeckerPiotr MieczkowskiGeorge S HannaMark Todd Hamann

mutagenesismutagenesis (molecular biology technique)biochemistrysingle-stranded dnamolecular biologydna repairgenetics

Spiroamentotaxols a–D: Unprecedented 6/6/6/5/6/6/6/6 Spiro-Octacyclic Bis-Diterpene Heterodimers From the Endangered Conifer Amentotaxus Yunnanensis and Their Bioactivities. Organic Chemistry Frontiers (2025)

Peng-Jun ZhouZe-Yu ZhaoSha ChenGong-Pu LuoJin-Xin ZhuXu-Wen LiYeun-Mun ChooMark T. HamannJuan XiongJin-Feng Hu

spiroamentotaxols a-dplant biodiversityenvironmental sciencebotanybiologychemical biologyfunctional ecologychemical ecologyphytochemicalsecologyplant sciencespiro-octacyclic bis-diterpene heterodimers

A Toxic Sterolysin From a 1950S Culture of Gymnodinium Veneficum Ballantine.. Research Square (2024)

Allen R. PlaceJosefina Ramos-FrancoAmanda L. WatersMark T. Hamann

toxic sterolysinvascular biologypathologyinhibitory activityfungusbiochemistrymicrobiologytoxinsgymnodinium veneficum ballantine

Cannabinoid-Inspired Inhibitors of the Sars-Cov-2 Coronavirus 2′-O-Methyltransferase (2′-O-Mtase) Non-Structural Protein (Nsp10–16). Molecules (2024)

Menny M. BenjaminGeorge S. HannaCody F. DickinsonYeun-Mun ChooXiaojuan WangJessica A. Downs-BowenRamyani DeTamara R. McBrayerRaymond F. SchinaziSarah E. NielsonJoan M. HevelPankaj PandeyRobert J. DoerksenDanyelle M. TownsendJie ZhangZhiwei YeScott WyerLucas BialousowMark T. Hamann

antiviral drug developmentantiviral compoundssars-cov-2 coronavirusmedicinal chemistrybiochemistryantiviral researchnovel biphenylpyranpharmacologycannabinoid-inspired inhibitorsdrug discoveryenzyme inhibition

Computationally-Assisted Discovery and Assignment of a New Class of 6/6/5/5 Fused-Ring Diterpene Acting as Pregnane X Receptor Ligands From Isodon Serra. Journal of Natural Products (2024)

Zhiwei BianXiaoying LiuShian HuHongyi LiJared S. WoodR. Thomas WilliamsonJiabao LiuYing ChenJin ShiCarolyn L. CumminsDaneel FerreiraYeun-Mun ChooShengpeng WangMark T. HamannXiaojuan Wang

natural product biosynthesisnatural productssynthetic biologybioactive compoundstherapeutic targetsmolecular dockingmolecular biologydrug discoverynatural product researchbiochemistryfused-ring diterpeneprotein sciencepeptide sciencereceptor (biochemistry)rational drug designtransition metal chemistrynatural product synthesiscomputationally-assisted discoveryenzyme inhibitionbiomolecular engineering

High-Value Flavonoids With Potential Anti-Inflammatory Benefits From Platanus × Acerifolia Willd Leaves: Turning Waste Into Treasure. Phytochemistry Letters (2024)

Xi-Ying WuZe-Yu ZhaoEzzat E.A. OsmanYeun-Mun ChooJuan XiongMark T. HamannJin-Feng Hu

natural product researchphytochemistrynatural productswilld leavesphytopharmacologyphytochemical analysissecondary metaboliteshigh-value flavonoidsbioactive compoundspotential anti-inflammatory benefitsphytochemicalspolyphenolicsphytotherapy researchantioxidantsbiomolecular engineering

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Mark T. Hamann

Professor Charles and Carol Cooper/SmartState Endowed Chair of Drug Discovery and Biomedical Sciences

Medical University of South Carolina

Affiliations

College of Pharmacy

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mark T. Hamann

Medical University of South Carolina

Professor Charles and Carol Cooper/SmartState Endowed Chair of Drug Discovery and Biomedical Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Evaluation of Marine Natural Products for Neuritogenesis in Murine Primary Cortical Cultures (Abstract Id: 160003). Journal of Pharmacology and Experimental Therapeutics (2025)

aquaculturemariculturenatural productsembryologyabstract idmarine natural productsdevelopmental biologybiologymarine drugmarine biologydevelopmental neurobiologymarine biotechnology

Exploring the Therapeutic Potential of Mitragynine and Corynoxeine: Kratom-Derived Indole and Oxindole Alkaloids for Pain Management. Pharmaceuticals (2025)

Ahmed S. AlfordHope L. MorenoMenny M. BenjaminCody F. DickinsonMark T. Hamann

pharmaceutical scienceskratom-derived indoleoxindole alkaloidstherapeutic potentialpharmacologypain therapypain medicinepain management

Manzamine a: A Promising Marine-Derived Cancer Therapeutic for Multi-Targeted Interactions With E2F8, Six1, Ar, Gsk-3β, and V-Atpase - a Systematic Review. European Journal of Pharmacology (2025)

Mohammad Amir MishanYeun-Mun ChooJeffery WinklerMark T HamannDev Karan

Marine Metabolites for the Sustainable and Renewable Production of Key Platform Chemicals. Processes (2025)

Methylglyoxal Mutagenizes Single-Stranded Dna via Rev1-Associated Slippage and Mispairing. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Natalie SainiSriram VijayraghavanAlessandra RuggieroSamuel BeckerPiotr MieczkowskiGeorge S HannaMark Todd Hamann

mutagenesismutagenesis (molecular biology technique)biochemistrysingle-stranded dnamolecular biologydna repairgenetics

Peng-Jun ZhouZe-Yu ZhaoSha ChenGong-Pu LuoJin-Xin ZhuXu-Wen LiYeun-Mun ChooMark T. HamannJuan XiongJin-Feng Hu

A Toxic Sterolysin From a 1950S Culture of Gymnodinium Veneficum Ballantine.. Research Square (2024)

Allen R. PlaceJosefina Ramos-FrancoAmanda L. WatersMark T. Hamann

toxic sterolysinvascular biologypathologyinhibitory activityfungusbiochemistrymicrobiologytoxinsgymnodinium veneficum ballantine

Cannabinoid-Inspired Inhibitors of the Sars-Cov-2 Coronavirus 2′-O-Methyltransferase (2′-O-Mtase) Non-Structural Protein (Nsp10–16). Molecules (2024)

Computationally-Assisted Discovery and Assignment of a New Class of 6/6/5/5 Fused-Ring Diterpene Acting as Pregnane X Receptor Ligands From Isodon Serra. Journal of Natural Products (2024)

Zhiwei BianXiaoying LiuShian HuHongyi LiJared S. WoodR. Thomas WilliamsonJiabao LiuYing ChenJin ShiCarolyn L. CumminsDaneel FerreiraYeun-Mun ChooShengpeng WangMark T. HamannXiaojuan Wang

High-Value Flavonoids With Potential Anti-Inflammatory Benefits From Platanus × Acerifolia Willd Leaves: Turning Waste Into Treasure. Phytochemistry Letters (2024)

Xi-Ying WuZe-Yu ZhaoEzzat E.A. OsmanYeun-Mun ChooJuan XiongMark T. HamannJin-Feng Hu

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medicinal chemistry

pharmacology

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Institution

Purdue University

medicinal chemistry

pharmacology

Duane D. Miller

Institution

University of Tennessee Health Science Center

pharmacology

medicinal research

Hendrik Luesch

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marine cyanobacteria

natural product biosynthesis

David Kingston

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phytochemistry

pharmacology

Wei Li

Institution

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pharmacology

oncology

Robert H. Cichewicz

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natural product

infectious diseases

Arun Ghosh

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Purdue University

bio-orthogonal chemistry

bioactive peptides

Nicholas Oberlies

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University of North Carolina at Greensboro

natural product communication

herb-drug interaction

Chang-Guo Zhan

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future medicinal chemistry

molecular docking