Donovan Haines

Professor of Chemistry

Sam Houston State University

Affiliations

College of Science and Engineering Technology

Department of Chemistry

Donovan Haines is currently serving as a College Of Science And Engineering Technology Professor of Chemistry at Sam Houston State University.

Honors

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Experiences

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Education

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Donovan Haines

Sam Houston State University

Professor of Chemistry

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biochemistry pharmacology molecular biology protein structure enzymes protein science structural biology redox biology genetics medicinal chemistry drug discovery biotechnology biochemical sciences biomolecular structure structural molecular biology antioxidants applied microbiology protein chemistry surface reactivity biomolecular interactions carbonyl metabolism bacteriology plant ecology toxicological mechanism crystallography surface science peptides death studies microbial cell factory cell metabolism clinical microbiology bioenergetics tree physiology forest ecology molecular metabolism crystal structures surface chemistry molecular substrates molecular biotechnology catalyst activation aeronautics space environment thanatology death investigation heme signaling in-situ conversion mitochondrial function drug assessment host-microbe interactions cyanobacteria phycology bioluminescence immunomodulation phytoalexins tree growth phenology dopamine alcohol dehydrogenases experimental toxicology phytopharmacology pivotal role obligatory intermolecular electron-transfer flavin analogue substitution fmn-binding domain suicide enzyme inhibitors kinetic analysis product formation single active-site mutation single mutation homoserine lactone acyl homoserine substrate nucleophilic substitution reactions phenacyl bromide oxime substrate binding dopamine b-mono-oxygenase reaction electron transfer hormone metabolism drug metabolism

Notable Scholarly Works

Notable Federal Grants

Collaborators

Remains Containment Considerations for Death in Low-Earth Orbit. Aerospace Medicine and Human Performance (2023)

Travis HouserKjell N. LindgrenEdward L. MazuchowskiMichael R. BarrattDonovan C. HainesMadri JayakodyRebecca S. BlueJoan A. BythewayPhilip C. Stepaniak

medicinedeath investigationlow-earth orbitthanatologyspace explorationdeath studiesremains containment considerationsspace environmentaerospace engineeringaeronauticshuman performancemortality

Is Oak Mistletoe Host Species Distribution the Result of the Correlation Between Seasonal Patterns of Host Tree Growth and Mistletoe Phenology?. (2019)

tree growthforestrybiodiversitytree physiologybiologycommunity (ecology)forest ecologyplant ecologyecologyphenology

Variation in Monoterpene Emissions Across Potential Hosts and Over Time as an Explanation of Local Host Preference in Phorandendron Leucarpum (Raf.) Reveal & MC Johnst.(Viscaceae). (2019)

biodiversityphotosynthesisbiologychemical ecologyecology and evolutionary biologyecologyplant scienceplant ecologybotany

Aluminum‐Substituted Heme Domain of P450Bm‐3 (Bmp): Introducing a Heme‐Derived Fluorescent Probe for Studies of Substrate Binding and Protein–Protein Interactions in …. (2013)

heme signalingprotein structurebiomolecular structuremolecular biologystructural molecular biologybiochemistrystructural biologyprotein scienceprotein engineeringprotein folding

Comparison of Brain Mitochondrial Cytochrome C Oxidase Activity With Cyanide Ld50 Yields Insight Into the Efficacy of Prophylactics. (2013)

pharmacologyantioxidantsredox biologymitochondrial functionoxidative stressneurosciencecell metabolism

A Single Residue With Dramatic Impact on Substrate‐ Induced Spin‐State Change in P450Bm‐3. The FASEB Journal (2012)

Donovan C. HainesAmita HegdeBaozhi ChenDiana TomchickWeiqiang ZhaoMuralidhar BondlelaJohn M. HumphreysDavid A. MullinMischa MachiusJulian A. Peterson

physiologypharmacologyin-situ conversionsurface reactivityprotein structuresingle residueenzymesmolecular biologystructural biologyprotein sciencenanotechnology

Creating a Drug Assay With Synthetic Biology Using the Barbiturate‐Responsive Repressor Bm3r1. The FASEB Journal (2012)

Asheley Monique CorizDonovan C Haines

pharmacologydrug discoverydrug assaydrug assessmentsynthetic biology

Identification and Analysis of a Quorum Sensing Interference Compound From Medicago Sativa on Sinorhizobium Meliloti.. (2012)

applied microbiologyphytoalexinsbioactive compoundsanalytical chemistrymicroorganismsmicrobiology

Peroxidase-Like Activity of Uncoupled Cytochrome P450: Studies With Bilirubin and Toxicological Implications of Uncoupling. (2012)

in vitro toxicologydrug metabolismheme degradationtoxinsenzymestoxicologyanalytical toxicologytoxicological mechanismbiochemistry

A Single Active-Site Mutation of P450Bm-3 Dramatically Enhances Substrate Binding and Rate of Product Formation. Biochemistry (2011)

Donovan C. HainesAmita HegdeBaozhi ChenWeiqiang ZhaoMuralidhar BondlelaJohn M. HumphreysDavid A. MullinDiana R. TomchickMischa MachiusJulian A. Peterson

pharmacologygeneticsproduct formationsingle active-site mutationstructural biologybiochemistry

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