Faculty

Institution

Unit

Venue

Guocan Wang

The University of Texas MD Anderson Cancer Center

Affiliations

Center For Rna Interference And Non-Coding Rna

Department Of Cancer Biology

Department Of Biology And Biochemistry

Department Of Epigenetics And Molecular Carcinogenesis

Division Of Medical Oncology

MD Anderson UTHealth Houston Graduate School

The University of Texas MD Anderson Cancer Center

NoneGuocan Wang is currently serving as a Center For Rna Interference And Non-Coding Rna faculty at The University of Texas Md Anderson Cancer Center.

Honors

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Experiences

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Education

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Guocan Wang

The University of Texas MD Anderson Cancer Center

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cancer research cancer biology oncology tumor biology prostate cancer urology medicinal research cancer genetics genetics immunology oncogenes molecular cancer cancer cells cell biology cancer genomics metastasis tumor targeting cancer immunotherapy cancer treatment gene expression cellular therapy cancer care cell regulation tumor microenvironment brain tumor research molecular cell biology tumor suppressors cancer immunosurveillance vascular biology mammalian biology cell death protein science cellular senescence genitourinary cancers cancer discovery stem cell research cell research bone research biological microenvironments chromatin remodeling angiogenesis epigenetic changes molecular regulation gene regulation adaptive immune system medical genetics genetic disorders colorectal cancer clinical effectiveness clinical medicine clinical reviews rna biology gene function cellular biology molecular substrates molecular evidence treatment development host genetics host response biological function immune therapy resistance immunological changes tumor evolution hypoxia reduction cell infiltration epigenetic activation stem cell differentiation invasive growth oncogenic function phosphorylation-dependent regulation cytosolic localization pten-deficient cancer synthetic essentiality prostate tumors telomerase reactivation bone metastases

Notable Scholarly Works

Notable Federal Grants

Collaborators

Kdm4A Promotes Nepc Progression Through Regulation of Myc Expression. Cancer Letters (2025)

cell signalingtranscription factorsmolecular cell biologyoncogenessignal transductioncell regulationnepc progressioncell biology

The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression. Cancer Cell (2025)

immunologycoordinating stemnessmetastasismolecular cancerurologytumor suppressorsmolecular cell biologyprostate canceroncogenescancer cellscancer biologytumor biologyimmune suppressioncell biology

Abstract 1803: Acod1 is a Key Regulator of Immunosuppressive Mdscs, Prostate Cancer Progression, and Resistance to Immunotherapy. Cancer Research (2024)

Celia Sze Ling MakXin LiangJessica SuhDerek LiangMing ZhuGuocan Wang

immunosuppressive therapypharmacologycancer carecancer managementcancer researchurologycancer immunotherapyimmunosuppressive mdscsoncologykey regulatormedicinal researchcancer treatmentprostate cancer progressioncancer biologyimmunosuppressionprostate cancerhealth sciencesimmunotherapy

Prostate Cancer–Induced Endothelial-Cell-To-Osteoblast Transition Drives Immunosuppression in the Bone–Tumor Microenvironment Through Wnt Pathway–Induced M2 Macrophage Polarization. Proceedings of the National Academy of Sciences (2024)

immunologym2 macrophage polarizationurologycellular therapycancer growthbone–tumor microenvironmentcancer cellstumor microenvironmentcancer biologyprostate cancerbiological microenvironmentscell biology

Targeting Prmt3 Impairs Methylation and Oligomerization of Hsp60 to Boost Anti-Tumor Immunity by Activating Cgas/Sting Signaling. Nature Communications (2024)

immunologysignaling pathwaysanti-tumor immunitycell deathcell regulationcancer biologyprmt3 impairs methylationcell signalingmolecular cancertherapeutic targetsmolecular cell biologymolecular biologyoncogenescancer cellsepigeneticssignal transductiontumor biologycell biology

Data From a Genetic Platform to Model Sarcomagenesis From Primary Adult Mesenchymal Stem Cells. (2023)

Jlenia GuarnerioLuisa RiccardiRiccardo TaulliTakahiro MaedaGuocan WangRobin M. HobbsMin Sup SongPaolo SportolettiRosa BernardiRoderick T. BronsonMireia Castillo-MartinCarlos Cordon-CardoAndrea LunardiPier Paolo Pandolfi

stem cellsgeneticsmesenchymal stem cellsgenetic platform

Data From Targeting Yap-Dependent Mdsc Infiltration Impairs Tumor Progression. (2023)

Guocan WangXin LuPrasenjit DeyPingna DengChia Chin WuShan JiangZhuangna FangKun ZhaoRamakrishna KonaparthiSujun HuaJianhua ZhangElsa M. Li-Ning-TapiaAvnish KapoorChang-Jiun WuNeelay Bhaskar PatelZhenglin GuoVandhana RamamoorthyTrang N. TieuTim HeffernanDi ZhaoXiaoying ShangSunada KhadkaPingping HouBaoli HuEun-Jung JinWantong YaoXiaolu PanZhihu DingYanxia ShiLiren LiQing ChangPatricia TroncosoChristopher J. LogothetisMark J. McArthurLynda ChinY. Alan WangRonald A. DePinho

immunologytumor targetingleukemiapharmacologymetastasisradiation oncologycancer researchmolecular cancercancer immunosurveillancecancer genomicscancer immunotherapycellular therapyoncologyoncogenesmedicinal researchdrug targetingcancer biologytumor biology

Data Supplement From the Rac1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of Raf. (2023)

Ian R. WatsonLiren LiPeter K. CabeceirasMozhdeh MahdaviTony GutschnerGiannicola GenoveseGuocan WangZhuangna FangJames M. TepperKatherine Stemke-HaleKenneth Y. TsaiMichael A. DaviesGordon B. MillsLynda Chin

pharmacologymelanomacancer geneticscancer researchgeneticsdrug resistancepharmacological inhibitiononcologydata supplementskin cancer

EDITORIAL: Interplay Between Epigenetic Modifiers and Transcription Factors in Driving Cancer Progression. Frontiers in Oncology (2023)

carcinogenesiscancer progressioncancer geneticscancer researchmolecular cancerepigenetic changesgeneticstranscription factorsepigenetic modifiersoncogenescancer cellsepigeneticscell biology

Endothelial-To-Osteoblast Transition in Normal Mouse Bone Development. iScience (2023)

Song-Chang LinGuoyu YuYu-Chen LeeJian H. SongXingzhi SongJianhua ZhangTheocharis PanaretakisChristopher J. LogothetisYoshihiro KomatsuLi-Yuan Yu-LeeGuocan WangSue-Hwa Lin

angiogenesismammalian biologymorphogenesisendothelial-to-osteoblast transitiondevelopmental biologytissue developmenttissue (biology)bone researchcell biology

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Guocan Wang

The University of Texas MD Anderson Cancer Center

Affiliations

Center For Rna Interference And Non-Coding Rna

Department Of Cancer Biology

Department Of Biology And Biochemistry

Department Of Epigenetics And Molecular Carcinogenesis

Division Of Medical Oncology

MD Anderson UTHealth Houston Graduate School

The University of Texas MD Anderson Cancer Center

NoneGuocan Wang is currently serving as a Center For Rna Interference And Non-Coding Rna faculty at The University of Texas Md Anderson Cancer Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Guocan Wang

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Kdm4A Promotes Nepc Progression Through Regulation of Myc Expression. Cancer Letters (2025)

cell signalingtranscription factorsmolecular cell biologyoncogenessignal transductioncell regulationnepc progressioncell biology

The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression. Cancer Cell (2025)

immunologycoordinating stemnessmetastasismolecular cancerurologytumor suppressorsmolecular cell biologyprostate canceroncogenescancer cellscancer biologytumor biologyimmune suppressioncell biology

Abstract 1803: Acod1 is a Key Regulator of Immunosuppressive Mdscs, Prostate Cancer Progression, and Resistance to Immunotherapy. Cancer Research (2024)

Celia Sze Ling MakXin LiangJessica SuhDerek LiangMing ZhuGuocan Wang

Targeting Prmt3 Impairs Methylation and Oligomerization of Hsp60 to Boost Anti-Tumor Immunity by Activating Cgas/Sting Signaling. Nature Communications (2024)

Data From a Genetic Platform to Model Sarcomagenesis From Primary Adult Mesenchymal Stem Cells. (2023)

stem cellsgeneticsmesenchymal stem cellsgenetic platform

Data From Targeting Yap-Dependent Mdsc Infiltration Impairs Tumor Progression. (2023)

Data Supplement From the Rac1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of Raf. (2023)

pharmacologymelanomacancer geneticscancer researchgeneticsdrug resistancepharmacological inhibitiononcologydata supplementskin cancer

EDITORIAL: Interplay Between Epigenetic Modifiers and Transcription Factors in Driving Cancer Progression. Frontiers in Oncology (2023)

carcinogenesiscancer progressioncancer geneticscancer researchmolecular cancerepigenetic changesgeneticstranscription factorsepigenetic modifiersoncogenescancer cellsepigeneticscell biology

Endothelial-To-Osteoblast Transition in Normal Mouse Bone Development. iScience (2023)

Song-Chang LinGuoyu YuYu-Chen LeeJian H. SongXingzhi SongJianhua ZhangTheocharis PanaretakisChristopher J. LogothetisYoshihiro KomatsuLi-Yuan Yu-LeeGuocan WangSue-Hwa Lin

angiogenesismammalian biologymorphogenesisendothelial-to-osteoblast transitiondevelopmental biologytissue developmenttissue (biology)bone researchcell biology

1
2
3
4
5
10 / page