Faculty

Institution

Unit

Venue

Gordon C. Weir

Professor

Harvard University

Affiliations

Harvard Faculty of Arts and Sciences

Harvard Stem Cell Institute

Gordon C. Weir is currently serving as a Harvard Faculty Of Arts And Sciences Professor at Harvard University.

Honors

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Experiences

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Education

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Gordon C. Weir

Harvard University

Professor

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endocrinology diabetes immunology pharmacology regenerative medicine cell biology health sciences membrane biology mammalian biology liver physiology transplantation medicine hepatology hematology cell transplantation organ transplantation clinical transplantation gene expression medicinal research molecular physiology endocrine research liver transplantation vascular biology animal physiology experimental medicine comparative endocrinology protein science diabetes therapies clinical investigation cellular physiology diabetic medicine graft survival diabetes mellitus insulin signaling tissue transplantation clinical biochemistry clinical physiology stem cell transplantation diabetes management transplant surgery islet transplantation metabolic regulation clinical medicine gene function biomedical research adaptive immune system mammalian physiology insulin delivery molecular regulation host factors renal function gene regulation cell regulation glucagon secretion mitochondrial function energy metabolism pancreas transplantation insulin secretion in vivo systems functional regulation cell proliferation human islets pancreatic islets b-cell mass host response disease progression gastrointestinal pharmacology rat model chronic hyperglycemia beta cells glucose-induced insulin secretion pancreatic b-cells non-human primates perfused rat pancreas partial pancreatectomy beta-cell adaptation laser capture microdissection

Notable Scholarly Works

Notable Federal Grants

Collaborators

Glucose-Stimulated Insulin Secretion via Perfusion Through the Mice Vasculature With an Intact Pancreas. Journal of Visualized Experiments (2025)

physiologydiabetesinsulin signalingbiomedical engineeringmetabolismdiabetes researchblood vessels

Renalase Inhibition Defends Against Acute and Chronic β Cell Stress by Regulating Cell Metabolism. Molecular Metabolism (2025)

physiologymetabolic remodelingcell biologyfree radical biologymolecular metabolismmetabolismbiochemistrycell metabolism

Enhancement of Subcutaneous Islet Transplant Performance by Collagen 1 Gel. Cell Transplantation (2024)

Anna FrenchJennifer Hollister-LockBrooke A. SullivanEline StasAlbert J. HwaGordon C. WeirSusan Bonner-Weir

polyelectrolyte gelgraft rejectionbiomedical engineeringhematologyregenerative medicinexenotransplantationvascular biologytransplant surgerytissue engineeringbiomolecular engineeringtransplantation medicineregeneration (biology)cell transplantationmedicinal researchtissue transplantationclinical transplantationbiological engineeringwound healing

Renalase Inhibition Regulates β Cell Metabolism to Defend Against Acute and Chronic Stress. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Tara MacDonaldBirgitta RybackJessica Aparecida da Silva PereiraSiying WeiBryhan MendezErica CaiYuki IshikawaGordon WeirSusan Bonner-WeirStephan KisslerPeng Yi

immunologyphysiologymetabolic regulationnephrologygeneticsrenalase inhibitionchronic stressmedicinal researchmolecular physiologymembrane biology

Conflicting Views About Interactions Between Pancreatic α-Cells and β-Cells. Diabetes (2023)

Gordon C. WeirSusan Bonner-Weir

immunologybiomolecular interactionsdermatologymedicinediabetescell interactionsadaptive immune systemcell-matrix interactionspancreatic a-cells

Identification of a Humanized Mouse Model for Functional Testing of Immune-Mediated Biomaterial Foreign Body Response. Science Advances (2023)

Joshua C. DoloffMinglin MaAtieh SadraeiHok Hei TamShady FarahJennifer Hollister-LockArturo J. VegasOmid VeisehVictor M. QuirozAmanda RakoskiStephanie Aresta-DaSilvaAndrew R. BaderMarissa GriffinGordon C. WeirMichael A. BrehmLeonard D. ShultzRobert LangerDale L. GreinerDaniel G. Anderson

immunologyfibrosisbiomedical engineeringfunctional tissue engineeringtissue engineeringmatrix biologycollagen matrix depositionhumanized mouse modelcellular therapyspatial resolutionextracellular matrixcell biology

Induction of Remission in Diabetes by Lowering Blood Glucose. Frontiers in Endocrinology (2023)

Gordon C. WeirSusan Bonner-Weir

blood glucosepharmacologydiabetesendocrinologydiabetes managementrelapse preventionhealth sciences

Contributors. Elsevier eBooks (2022)

Ron AltermanJeffrey E. ArleKerry BradleySergio CanaveroSteven M. FalowskiChad W. FarleyYakov GologorskyJianwen Wendy GuH. Louis JournéeJohn KastOlga KhazenJoachim K. KraussVignessh KumarMark LentRobert M. LevyAndres M. LozanoCharles MackelGeorge T. MandyburBryan L. McLaughlinDaniel R. MerrillAlon Y. MogilnerGabi MolnarGuillermo A. MonsalveRichard B. NorthYunseo Linda ParkJohn ParkerShrey PatelJulie G. PilitsisFrancisco A. PonceJason E. PopeAdolfo Ramirez-ZamoraLouis J. RasoJoshua M. RosenowJay L. ShilsPeter SingleKonstantin V. SlavinMichael D. StaudtMark M. SteckerHuy Q. Truong

Islet Inflammation Can Be Linked to the Disruption of Proinsulin Processing in Type 1 Diabetes but Not in Type 2 Diabetes. The Journal of Clinical Endocrinology & Metabolism (2022)

Gordon C Weir

diabetes carediabetesmetabolismgynecologydiabetes researchproinsulin processingneurologydiabetes therapiesendocrine oncologyendocrinologychronic diseasesgeriatric endocrinologyislet inflammationinsulin managementinflammationdiabetes epidemiologymetabolic syndromediabetes mellitusimmunologydiabetic medicine

Reduced Glucose-Induced First-Phase Insulin Release is a Danger Signal That Predicts Diabetes. Journal of Clinical Investigation (2021)

Gordon C. WeirSusan Bonner-Weir

diabetesepidemiologydiabetes managementclinical epidemiologydiabetes researchdiabetes therapiesthrombosismetabolic regulationendocrinologydanger signalcontrolled releaseinsulin signalingnephrologyclinical physiologydiabetes mellituspharmacologystatisticsclinical researchclinical investigation

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Gordon C. Weir

Professor

Harvard University

Affiliations

Harvard Faculty of Arts and Sciences

Harvard Stem Cell Institute

Gordon C. Weir is currently serving as a Harvard Faculty Of Arts And Sciences Professor at Harvard University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Gordon C. Weir

Harvard University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Glucose-Stimulated Insulin Secretion via Perfusion Through the Mice Vasculature With an Intact Pancreas. Journal of Visualized Experiments (2025)

physiologydiabetesinsulin signalingbiomedical engineeringmetabolismdiabetes researchblood vessels

Renalase Inhibition Defends Against Acute and Chronic β Cell Stress by Regulating Cell Metabolism. Molecular Metabolism (2025)

physiologymetabolic remodelingcell biologyfree radical biologymolecular metabolismmetabolismbiochemistrycell metabolism

Enhancement of Subcutaneous Islet Transplant Performance by Collagen 1 Gel. Cell Transplantation (2024)

Anna FrenchJennifer Hollister-LockBrooke A. SullivanEline StasAlbert J. HwaGordon C. WeirSusan Bonner-Weir

Renalase Inhibition Regulates β Cell Metabolism to Defend Against Acute and Chronic Stress. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Tara MacDonaldBirgitta RybackJessica Aparecida da Silva PereiraSiying WeiBryhan MendezErica CaiYuki IshikawaGordon WeirSusan Bonner-WeirStephan KisslerPeng Yi

immunologyphysiologymetabolic regulationnephrologygeneticsrenalase inhibitionchronic stressmedicinal researchmolecular physiologymembrane biology

Conflicting Views About Interactions Between Pancreatic α-Cells and β-Cells. Diabetes (2023)

Gordon C. WeirSusan Bonner-Weir

immunologybiomolecular interactionsdermatologymedicinediabetescell interactionsadaptive immune systemcell-matrix interactionspancreatic a-cells

Identification of a Humanized Mouse Model for Functional Testing of Immune-Mediated Biomaterial Foreign Body Response. Science Advances (2023)

Induction of Remission in Diabetes by Lowering Blood Glucose. Frontiers in Endocrinology (2023)

Gordon C. WeirSusan Bonner-Weir

blood glucosepharmacologydiabetesendocrinologydiabetes managementrelapse preventionhealth sciences

Contributors. Elsevier eBooks (2022)

Islet Inflammation Can Be Linked to the Disruption of Proinsulin Processing in Type 1 Diabetes but Not in Type 2 Diabetes. The Journal of Clinical Endocrinology & Metabolism (2022)

Gordon C Weir

Reduced Glucose-Induced First-Phase Insulin Release is a Danger Signal That Predicts Diabetes. Journal of Clinical Investigation (2021)

Gordon C. WeirSusan Bonner-Weir

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