Faculty

Institution

Unit

Venue

George Spirou

Professor

University of South Florida

Affiliations

College of Engineering

Department of Medical Engineering

George Spirou is currently serving as a College Of Engineering Professor at University of South Florida.

Honors

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Experiences

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Education

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George Spirou

University of South Florida

Professor

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neuroscience neuroanatomy neurophysiology systems neuroscience neurology hearing research developmental biology auditory science auditory physiology physiology nervous system audiology mammalian biology bioacoustics cognitive neuroscience electrophysiology developmental neurobiology cellular neurobiology animal physiology avian biology biomedical imaging spinal cord neural science brain circuitry electron microscopy clinical otolaryngology otorhinolaryngology psychoacoustics trapezoid body fish biology medical image computing clinical microbiology developmental cognitive neuroscience neural interfaces neuronal networks computed tomography pediatric otolaryngology graph analysis mitochondrial function acoustic signal processing neurological function embryonic development pinna-based spectral cues lateral nucleus engineering optimization animal behavior animal science speech processing animal cognition cognitive electrophysiology neurodynamics brain organization human physiology molecular neurobiology audio signal processing sensory science neurotology ultrastructure mammalian physiology in vivo systems 3d imaging image reconstruction tissue imaging synaptic architecture high-frequency transmission sound localization specialized synapse-associated structures complex stimuli neural organization high-rate metabolism electron tomography reveals active zones high-fidelity synapse bandlimited noise one-to-one morphological innervation neural development visual science immersive virtual reality bio-inspired computation virtual reality cognitive science

Notable Scholarly Works

Notable Federal Grants

Collaborators

Pre-Sensory Spontaneous Activity Accelerates Coordinated Maturation of Synaptic Partners and Drives Transition to the Mature Physiological Phenotype. bioRxiv (Cold Spring Harbor Laboratory) (2025)

developmental systemneural circuitsmature physiological phenotypeneurotransmissionsynaptic partnersbrain mechanismsdevelopmental biologyneuroscienceneuronsdevelopmental cognitive neuroscience

Cover Image, Volume 532, Issue 2. The Journal of Comparative Neurology (2024)

Daniel T. HellerDouglas R. KolsonAshley N. BrandeburaEmily M. AmickJun WanJad RamadanPaul S. HolcombSheng LiuThomas J. DeerinckMark H. EllismanJiang QianPeter H. MathersGeorge A. Spirou

neurologycomparative literaturecover imagemedical imagingneuroscience

Use of Three‐Dimensional ( 3D ) Airway Modeling and Virtual Reality for Diagnosis, Communication, and Surgical Planning of Complex Airway Stenosis. Head & Neck (2024)

Youngjun ChoGeorge SpirouSummer J. DeckerJonathan M. FordMatthew MifsudEric SommersYael Bensoussan

surgerycomputational imagingrehabilitation3d reconstructionthoracic surgerynumerical simulationsvirtual realityextended realityearly diagnosisprognostic evaluationmedical imagingmachine visiondifferential diagnosisradiology3d modelingaudiologycomplex airway stenosisrespiratory medicinetelehealth

Astrocyte Ensheathment of Calyx‐Forming Axons of the Auditory Brainstem Precedes Accelerated Expression of Myelin Genes and Myelination by Oligodendrocytes. The Journal of Comparative Neurology (2023)

Daniel T. HellerDouglas R. KolsonAshley N. BrandeburaEmily M. AmickJun WanJad RamadanPaul S. HolcombSheng LiuThomas J. DeerinckMark H. EllismanJiang QianPeter H. MathersGeorge A. Spirou

neurologygene expressionmyelin genesgeneticscalyx-forming axonssystems neuroscienceneurophysiologyneuroscienceneuroanatomyastrocyte ensheathment

Gene Expression Changes and Myelination During Neural Circuit Pruning. Journal of Comparative Neurology (2023)

cellular physiologyneural circuitsmolecular neurosciencespinal cordneurological functionneural circuit pruningneuroscienceneurons

High-Resolution Volumetric Imaging Constrains Compartmental Models to Explore Synaptic Integration and Temporal Processing by Cochlear Nucleus Globular Bushy Cells. eLife (2023)

auditory physiologytemporal processingfunctional imagingneural circuitsneuroimagingsystems neurosciencemedical image computingsynaptic integrationhearing researchbrain mappingbiomedical imagingcognitive scienceneuroscienceneuroanatomybrain circuitry

Two Synaptic Convergence Motifs Define Functional Roles for Synaptic Inputs to Cochlear Nucleus Bushy Cells. eLife (2023)

nucleus bushy cellsauditory physiologyneural mechanismssynaptic convergence motifsneural circuitssynaptic inputsneurotransmissionneurolinguisticshearing researchbrain mechanismsdevelopmental biologycellular neurobiologyneuroscienceneuroanatomyneurons

Simulations of Cochlear Nucleus Bushy Cells Reconstructed From Serial Blockface Electron Microscopy (V1.0). Figshare (2022)

Paul ManisGeorge SpirouMark Ellisman

biophysicsmicroscopyelectron microscopyneurosciencecell biology

Transcriptional Profiling Reveals Roles of Intercellular Fgf9 Signaling in Astrocyte Maturation and Synaptic Refinement During Brainstem Development. Journal of Biological Chemistry (2022)

Ashley N. BrandeburaDouglas R. KolsonEmily M. AmickJad RamadanMatthew C. KerstingRobert H. NicholPaul S. HolcombPeter H. MathersPeter StoilovGeorge A. Spirou

gene expressionbrainstem developmentastrocyte maturationdevelopmental neurobiologymolecular biologydevelopmental biologysynaptic refinementcell biology

Automatic Quasi-Clique Merger Algorithm — a Hierarchical Clustering Based on Subgraph-Density. Physica A Statistical Mechanics and its Applications (2021)

Scott PayneEdgar FullerGeorge SpirouCun-Quan Zhang

hierarchical clusteringgraph theorygraph analysisapplied mathematicsclusteringstatistical mechanics

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George Spirou

Professor

University of South Florida

Affiliations

College of Engineering

Department of Medical Engineering

George Spirou is currently serving as a College Of Engineering Professor at University of South Florida.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

George Spirou

University of South Florida

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Pre-Sensory Spontaneous Activity Accelerates Coordinated Maturation of Synaptic Partners and Drives Transition to the Mature Physiological Phenotype. bioRxiv (Cold Spring Harbor Laboratory) (2025)

developmental systemneural circuitsmature physiological phenotypeneurotransmissionsynaptic partnersbrain mechanismsdevelopmental biologyneuroscienceneuronsdevelopmental cognitive neuroscience

Cover Image, Volume 532, Issue 2. The Journal of Comparative Neurology (2024)

Daniel T. HellerDouglas R. KolsonAshley N. BrandeburaEmily M. AmickJun WanJad RamadanPaul S. HolcombSheng LiuThomas J. DeerinckMark H. EllismanJiang QianPeter H. MathersGeorge A. Spirou

neurologycomparative literaturecover imagemedical imagingneuroscience

Use of Three‐Dimensional ( 3D ) Airway Modeling and Virtual Reality for Diagnosis, Communication, and Surgical Planning of Complex Airway Stenosis. Head & Neck (2024)

Youngjun ChoGeorge SpirouSummer J. DeckerJonathan M. FordMatthew MifsudEric SommersYael Bensoussan

Daniel T. HellerDouglas R. KolsonAshley N. BrandeburaEmily M. AmickJun WanJad RamadanPaul S. HolcombSheng LiuThomas J. DeerinckMark H. EllismanJiang QianPeter H. MathersGeorge A. Spirou

neurologygene expressionmyelin genesgeneticscalyx-forming axonssystems neuroscienceneurophysiologyneuroscienceneuroanatomyastrocyte ensheathment

Gene Expression Changes and Myelination During Neural Circuit Pruning. Journal of Comparative Neurology (2023)

cellular physiologyneural circuitsmolecular neurosciencespinal cordneurological functionneural circuit pruningneuroscienceneurons

High-Resolution Volumetric Imaging Constrains Compartmental Models to Explore Synaptic Integration and Temporal Processing by Cochlear Nucleus Globular Bushy Cells. eLife (2023)

Two Synaptic Convergence Motifs Define Functional Roles for Synaptic Inputs to Cochlear Nucleus Bushy Cells. eLife (2023)

Simulations of Cochlear Nucleus Bushy Cells Reconstructed From Serial Blockface Electron Microscopy (V1.0). Figshare (2022)

Paul ManisGeorge SpirouMark Ellisman

biophysicsmicroscopyelectron microscopyneurosciencecell biology

Transcriptional Profiling Reveals Roles of Intercellular Fgf9 Signaling in Astrocyte Maturation and Synaptic Refinement During Brainstem Development. Journal of Biological Chemistry (2022)

Ashley N. BrandeburaDouglas R. KolsonEmily M. AmickJad RamadanMatthew C. KerstingRobert H. NicholPaul S. HolcombPeter H. MathersPeter StoilovGeorge A. Spirou

gene expressionbrainstem developmentastrocyte maturationdevelopmental neurobiologymolecular biologydevelopmental biologysynaptic refinementcell biology

Automatic Quasi-Clique Merger Algorithm — a Hierarchical Clustering Based on Subgraph-Density. Physica A Statistical Mechanics and its Applications (2021)

Scott PayneEdgar FullerGeorge SpirouCun-Quan Zhang

hierarchical clusteringgraph theorygraph analysisapplied mathematicsclusteringstatistical mechanics

1
2
3
4
5
6
7
10 / page

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West Virginia University

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