Faculty

Institution

Unit

Venue

Ganiraju Manyam

The University of Texas MD Anderson Cancer Center

Affiliations

Metabolomics Core Facility

Department Of Bioinformatics And Computational Biology

The University of Texas MD Anderson Cancer Center

Ganiraju Manyam is a Senior Professor at The University of Texas MD Anderson Cancer Center. Specializing in oncology and cancer research, his work integrates cancer biology, pharmacology, and genetics to advance precision medicine. His recent investigations focus on the transcriptional analysis of NDRG1 amplification in aggressive breast cancerchers and the temporospatial activation of STAT3 signaling in colorectal cancer progression. He has also explored immunologic biomarkers for resistance and response to cabozantinib and nivolumab in recurrent endometrial cancer, as well as molecular subtypes of bladder cancer. His expertise in cancer immunotherapy underpins international collaborations in checkpoint blockade trials and circulating tumor DNA studies.

Honors

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Experiences

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Education

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Ganiraju Manyam

The University of Texas MD Anderson Cancer Center

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oncology cancer research immunology cancer biology medicinal research pharmacology tumor biology cancer immunotherapy molecular cancer genetics oncogenes colorectal cancer cancer genomics medicine lymphoid neoplasia cancer genetics cancer care cancer treatment immunotherapy hematology cellular therapy gene expression cancer cells leukemia hematological malignancies surgical oncology cell signaling cancer management enzyme inhibition anti-cancer agents tumor targeting therapeutic efficacy large b-cell lymphoma medical mycology cancer discovery signaling pathways genitourinary cancers drug targeting gastrointestinal oncology clinical mycology histopathology molecular cell biology clinical pathology cancer growth clinical implications surgical pathology experimental medicine viral oncology myeloid neoplasia prognosis metastatic colorectal cancer cytokines rna biology apoptosis cancer risk cell regulation clinical immunology consensus molecular subtypes inflammatory breast cancer bayesian analysis gene function gene regulation adaptive immune system omics integration tumor characteristics genomics data androgen receptor castration-resistant prostate cancer parp inhibition inhibitory activity master transcriptional repressor favorable prognosis novel subgroup tgf-b superfamily integrative bayesian analysis proteomic characterization

Notable Scholarly Works

Notable Federal Grants

Collaborators

644 Temporospatial Activation of Signal Transducer and Activator of Transcription 3 (Stat3) and Its Transcriptome Signature in the Transition From Normal to Cancer in Colons of Patients at High Risk for Colorectal Cancer. Laboratory Investigation (2026)

oncogenescolorectal cancerpathologygastrointestinal oncologysignal transducerhigh riskcell biologytranscription factorsmolecular cancercancer researchmolecular gastroenterologygene expressioncancer biology

Abstract 1181: Transcriptomic Analysis of Ndrg1 Amplification in Aggressive Breast Cancer.. Cancer Research (2026)

breast oncologyoncogenestumor biologycancer biologyabstract 1181cell biologymolecular cancermolecular cell biologymolecular diagnosticsaggressive breast cancermolecular biologyndrg1 amplificationcancer cellscancer geneticscancer genomicsbreast cancer

Abstract 3123: Fracturing the Tumor-Bone Alliance in Metastatic Prostate Cancer With Ra-223. Cancer Research (2025)

Pablo SanchisAgustina SabaterJuan BizzottoGaston PascualNicolas AnselminoJiabin DongJun YangGaniraju ManyamBradley BroomZhongcheng ShiShixia HuangRocio SeniukEleonora DondossolaTeocharis PanaretakisJohn AraujoPeter ShepherdPatricia TroncosoNora NavoneChristopher J. LogothetisDaniel E. FrigoElba VazquezPaul CornGeraldine GueronEstefania Labanca

metastatic prostate cancertumor-bone allianceprostate cancercancer researchcancer biology

Biologic Correlates of Circulating Tumor Dna (Ctdna) Shedding in the Intercept Colorectal Cancer (Crc) Study.. Journal of Clinical Oncology (2025)

colorectal cancerpathologyradiation oncologytumor biologybiologic correlatesmolecular pathologymolecular cancertumor dnacancer researchmolecular diagnosticscancer detectionbiomarkerscancer cellsintercept colorectal cancercancer genomicsoncology

Chromosome 20Q Gene Signature Associated With Colorectal Cancer Progression. Oncology Reports (2025)

oncogenescolorectal cancerpathologytumor biologychromosome 20qmolecular cancermolecular diagnosticshuman geneticscancer geneticscancer genomicsgenetics

Immunological Biomarkers of Response and Resistance to Treatment With Cabozantinib and Nivolumab in Recurrent Endometrial Cancer. Journal for ImmunoTherapy of Cancer (2025)

Vladimir RoudkoDiane Marie Del ValleEmir RadkevichGeoffrey KellyXie HuiManishkumar PatelEdgar Gonzalez-KozlovaKevin TuballesHoward StreicherSwati AtaleLisa WangBenito CzinCzinSeunghee Kim-SchulzeIgnacio I WistubaCara L HaymakerGheath Al-AtrashGaniraju ManyamJianjun ZhangRyan ThompsonMayte Suarez-FarinasStephanie LheureuxSacha Gnjatic

gynecologic oncologyimmunologycancer discoverytumor biologyimmunotherapycancer researchcancer treatmentreproductive immunologyoncogenesmedicinal researchrecurrent endometrial cancersystems biologyurologycancer managementtumor microenvironmentcancer biologycancer growthcancer geneticsoncology

Ip14-19 Novel Combination Therapy Using Lentiviral Interferon and Immune Checkpoint Blockade for Treatment of Bladder Cancer in a Murine Model. The Journal of Urology (2025)

bladder canceroncogenescancer immunotherapybiological therapiesimmunologymedicinal researchnovel therapiesimmunotherapymolecular cancergenitourinary cancersurologyimmune checkpoint inhibitorsoncology

Lmp7-Specific Inhibitor M3258 Modulates the Tumor Microenvironment of Triple-Negative Breast Cancer and Inflammatory Breast Cancer. Cancers (2025)

oncogenesmetastasistumor biologycancer immunotherapyimmunologymedicinal researchcell biologymolecular cancercellular therapycancer researchcancer discoverypharmacologytherapeutic targetscancer cellscancer lettertumor microenvironmentbreast cancer

Molecular Profiling of Bladder Cancer Xenografts Defines Relevant Molecular Subtypes and Provides a Resource for Biomarker Discovery.. Translational Oncology (2025)

Sharada MokkapatiGaniraju ManyamAlexis R SteinmetzCôme TholomierAlberto MartiniWoonyoung ChoiBogdon CzerniakByron H LeeColin P DinneyDavid J McConkey

bladder cancerbiomarker discoverytranslational researchmolecular profilingbladder cancer xenograftsmolecular biologybiomarkersoncology

Pharmacological Profiling in Cll Patients During Pirtobrutinib Therapy and Disease Progression. Blood Cancer Journal (2025)

pirtobrutinib therapycll patientsapplied pharmacologypharmacological profilingpharmacokineticsmedicinepharmacologytherapeutic targetsdrug discoverypharmacotherapypharmacological researchleukemiatranslational pharmacologytherapeutic efficacyclinical pharmacology

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Ganiraju Manyam

The University of Texas MD Anderson Cancer Center

Affiliations

Metabolomics Core Facility

Department Of Bioinformatics And Computational Biology

The University of Texas MD Anderson Cancer Center

Honors

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Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ganiraju Manyam

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1181: Transcriptomic Analysis of Ndrg1 Amplification in Aggressive Breast Cancer.. Cancer Research (2026)

Abstract 3123: Fracturing the Tumor-Bone Alliance in Metastatic Prostate Cancer With Ra-223. Cancer Research (2025)

metastatic prostate cancertumor-bone allianceprostate cancercancer researchcancer biology

Biologic Correlates of Circulating Tumor Dna (Ctdna) Shedding in the Intercept Colorectal Cancer (Crc) Study.. Journal of Clinical Oncology (2025)

Chromosome 20Q Gene Signature Associated With Colorectal Cancer Progression. Oncology Reports (2025)

oncogenescolorectal cancerpathologytumor biologychromosome 20qmolecular cancermolecular diagnosticshuman geneticscancer geneticscancer genomicsgenetics

Immunological Biomarkers of Response and Resistance to Treatment With Cabozantinib and Nivolumab in Recurrent Endometrial Cancer. Journal for ImmunoTherapy of Cancer (2025)

Ip14-19 Novel Combination Therapy Using Lentiviral Interferon and Immune Checkpoint Blockade for Treatment of Bladder Cancer in a Murine Model. The Journal of Urology (2025)

bladder canceroncogenescancer immunotherapybiological therapiesimmunologymedicinal researchnovel therapiesimmunotherapymolecular cancergenitourinary cancersurologyimmune checkpoint inhibitorsoncology

Lmp7-Specific Inhibitor M3258 Modulates the Tumor Microenvironment of Triple-Negative Breast Cancer and Inflammatory Breast Cancer. Cancers (2025)

Molecular Profiling of Bladder Cancer Xenografts Defines Relevant Molecular Subtypes and Provides a Resource for Biomarker Discovery.. Translational Oncology (2025)

Sharada MokkapatiGaniraju ManyamAlexis R SteinmetzCôme TholomierAlberto MartiniWoonyoung ChoiBogdon CzerniakByron H LeeColin P DinneyDavid J McConkey

bladder cancerbiomarker discoverytranslational researchmolecular profilingbladder cancer xenograftsmolecular biologybiomarkersoncology

Pharmacological Profiling in Cll Patients During Pirtobrutinib Therapy and Disease Progression. Blood Cancer Journal (2025)

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5
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10 / page