Faculty

Institution

Unit

Venue

Gang Zhou

Professor Assistant Professor

Augusta University

Affiliations

Medical College of Georgia

Department of Medicine

Gang Zhou is currently serving as a Medicine Professor Assistant Professor at Augusta University.

Honors

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Experiences

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Education

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Gang Zhou

Augusta University

Professor Assistant Professor

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immunology cancer immunotherapy oncology pharmacology cancer research cancer biology tumor biology medicine medicinal research immunotherapy cancer treatment immune responses cellular therapy cell biology cancer care t-regulatory cell cellular immune responses adaptive immune system tumor targeting cancer cells cell regulation clinical immunology tumor suppressors hematology gene expression leukemia molecular cancer cell therapy anti-cancer agents enzyme inhibition cancer management pharmacotherapy oncogenes drug targeting innate immune system cell death gene regulation cancer immunosurveillance therapeutic efficacy cancer discovery immunosuppression immunomodulation colorectal cancer cancer genomics antitumor immunity mammalian biology pharmacological research medical mycology molecular regulation pharmaceutical sciences developmental immunology transcription regulation cancer cell growth clinical investigation vascular biology host factors clinical effectiveness clinical medicine angiology angiogenesis protein secretion rna biology metastatic cascade spatiotemporal tumour granulocytic myeloid tumor-specific tregs single site eradicates therapeutic cancer vaccines tumor-specific tolerance exosomal micrornas human hepatoma cells t-cell responses immunosuppressive myeloid cells influenza virus infection tumor antigenicity tumor progression radiation oncology tumor microenvironment

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cyclic Nucleotide Phosphodiesterases as Drug Targets. Pharmacological Reviews (2025)

Michy P. KellyViacheslav O. NikolaevLeila GobejishviliClaire LugnierChristian HesslingerPeter NickolausDavid A. KassWalma Pereira de VasconcelosRodolphe FischmeisterStefan BrockePaul M. EpsteinGary A. PiazzaAdam B. KeetonGang ZhouMohammad Abdel-HalimAshraf H. AbadiGeorge S. BaillieMark A. GiembyczGraeme BolgerGretchen SnyderKjetil TaskenNathaniel E.B. SaiduMartina SchmidtManuela ZaccoloRalph T. SchermulyHengming KeRick H. CoteSoroush Mohammadi JouabadiAnton J.M. Roks

biosensorstumor targetingprotein sciencefuture medicinal chemistryprotein phosphorylationtherapeutic targetsreceptor (biochemistry)nucleic acidsdrug discoverydrug targetingmedicinal researcholigonucleotidesmolecular medicinetumor biologyneurosciencepharmacological researchbiochemistrycell biology

Abstract 1889 Multi-Omic Studies Reveal the Polyamine-Hypusine Axis as a Promising Avenue to Improve T-Cell Persistence and Metabolism for Adoptive Cell Therapy. Journal of Biological Chemistry (2024)

Mercy Kehinde-IgeOgacheko OkokoGang ZhouHuidong Shi

immunologyphysiologypharmacologycell therapyadoptive cell therapyregenerative medicinedrug metabolismt-cell persistencepolyamine-hypusine axiscancer immunotherapydrug discoverymulti-omic studiesbiological chemistrymulti-omics studiesprotein sciencecellular therapycell metabolism

Abstract 18: The Polyamine-Hypusine Axis is a Promising Avenue to Improve T-Cell Metabolism and Persistence for Adoptive Cell Therapy. Cancer Research (2024)

Mercy Kehinde-IgeOgacheko OkokoGang ZhouHuidong Shi

adoptive cell therapytumor targetingcancer carecancer managementpolyamine-hypusine axiscancer biologycell therapycancer researchcancer immunotherapyt-cell metabolismcancer treatmenttumor biologyimmunologypharmacologypromising avenueradiation oncologyoncologyclinical researchmedicinal researchcellular therapy

Abstract 2459: Adt-030 is a Novel Dual-Acting Ras/β-Catenin Inhibitor That Potentiates Antitumor Immunity. Cancer Research (2024)

Md Yeashin GaziOgacheko OkokoXin WangCaitlin BrandleXi ChenKhalda FadlallaAdam KeetonYulia MaxuitenkoCatherine HedrickHuidong ShiGary PiazzaGang Zhou

immunologyreceptorsenzyme inhibitionpharmacologyradiation oncologycancer researchnovel therapiespharmacotherapycancer immunotherapyanti-cancer agentsoncologybreast cancermedicinal researchcancer treatmentcancer biology

A Pan-Ras Inhibitor With a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer. Cancer Research (2024)

Jeremy B. FooteTyler E. MattoxAdam B. KeetonXi ChenForrest T. SmithKristy BerryThomas W. HolmesJunwei WangChung-hui HuangAntonio WardAMIT K. MitraVeronica Ramirez-AlcantaraCherlene HardyKarianne G. FletenKjersti FlatmarkKarina J. YoonSujith SarveshGanji P. NagarajuDhana Sekhar Reddy BandiYulia Y. MaxuitenkoJacaob ValiyaveettilJulienne L. CarstensDonald J. BuchsbaumJennifer YangGang ZhouElmar NurmemmedovIvan BabicVadim GaponekoHazem AbdelkarimMichael R. BoydGreg GormanUpender ManneSejong BaeBassel F. El-RayesGary A. Piazza

gastrointestinal cancertumor targetingunique mechanismcancer immunosurveillanceanti-cancer agentstumor microenvironmentcancer biologycancer researchcancer immunotherapypan-ras inhibitorcancer treatmenttumor biologyimmunotherapyimmunologypharmacologyradiation oncologycancer discoveryoncogenescancer cellsmedicinal researchcellular therapy

Calcium Nanoparticles Target and Activate T Cells to Enhance Anti-Tumor Function. Nature Communications (2024)

Wei YangZhizi FengXinning LaiJianwen LiZhengwei CaoFangchao JiangFanghui ChenShuyue ZhanFeng KongLi YangYong TengWendy T. WatfordGang ZhouJin Xie

nanomedicinenanoparticlestumor targetinganti-tumor functionanti-cancer agentstherapeutic nanomaterialsnanotechnologyimmune checkpoint inhibitorstherapeutic targetscancer immunotherapydrug targetingimmunologysystems biologynanoparticle researchcancer discoverybiomolecular engineeringoncogenesmedicinal researchcalcium nanoparticles targetcancer cells

Host-Derived Interleukin 1α Induces an Immunosuppressive Tumor Microenvironment via Regulating Monocyte-To-Macrophage Differentiation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Manikanda Raja Keerthi RajaGourab GuptaGrace AtkinsonKatie KathreinAlissa ArmstrongMichael GowerIgor RoninsonEugenia BroudeMenqiang ChenHao JiChang-uk LimHongjun WangDaping FanPeisheng XuJie LiGang ZhouHexin Chen

immunologyimmunosuppressive therapymedicinecytokinesadaptive immune systemimmunosuppressive tumor microenvironmentoncologyimmune responsesmonocyte-to-macrophage differentiationtumor microenvironmentimmunosuppression

Novel Celecoxib Derivative, Rf26, Blocks Colon Cancer Cell Growth by Inhibiting Pde5, Activating Cgmp/Pkg Signaling, and Suppressing β-Catenin-Dependent Transcription. Anti-Cancer Agents in Medicinal Chemistry (2024)

Sara SiglerMohammad Abdel-HalimReem K. FathallaLuciana Madeira Da SilvaAdam B. KeetonYulia Y. MaxuitenkoKristy BerryGang ZhouMatthias EngelAshraf H. AbadiGary A. Piazza

medicinal chemistryinhibitory activitybiochemistryanti-cancer agentscancer biologycancer researchnovel celecoxib derivativetherapeutic targetscancer growthcancer cell growthcancer treatmenttumor biologypharmacologypharmacotherapycancer discoveryb-catenin-dependent transcriptionbiomolecular engineeringoncologyoncogenesmedicinal researchcancer cells

Single-Cell Transcriptome Profiling of the Myeloid Cells Repopulating After Chemotherapy Identifies a Neutrophil-Like Monocyte Subset With Pro-Tumor Activities. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Zhi-chun DingGeorge I. ZhouOgacheko D. OkokoXin WangLocke J. BryanGang ZhouHuidong Shi

transcriptomeneutrophil-like monocyte subsetsingle-cell analysismolecular biologymyeloid cellspro-tumor activitiessingle-cell transcriptome profilingcell biology

Abstract 1633: Adt-030, a Novel Dual-Acting Ras and β-Catenin Inhibitor With Robust Antitumor Activity. Cancer Research (2023)

Veronica Ramirez-AlcantaraXi ChenMichele A. SchulerDennis OtaliWilliam GrizzleKristy BerryAntonio WardIvan BabicElmar NurmemmedovGang ZhouChengguo XingGreg GormanLori CowardYulia MaxuitenkoAdam B. KeetonGary A. Piazza

pharmacologycancer biologycancer researchmolecular cancercgmp-dependent protein kinasetherapeutic targetscancer growthanti-cancer agentspde10 inhibitory activityoncogenesmedicinal researchcancer cellslung cancercell biology

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Gang Zhou

Professor Assistant Professor

Augusta University

Affiliations

Medical College of Georgia

Department of Medicine

Gang Zhou is currently serving as a Medicine Professor Assistant Professor at Augusta University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Gang Zhou

Augusta University

Professor Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cyclic Nucleotide Phosphodiesterases as Drug Targets. Pharmacological Reviews (2025)

Mercy Kehinde-IgeOgacheko OkokoGang ZhouHuidong Shi

Abstract 18: The Polyamine-Hypusine Axis is a Promising Avenue to Improve T-Cell Metabolism and Persistence for Adoptive Cell Therapy. Cancer Research (2024)

Mercy Kehinde-IgeOgacheko OkokoGang ZhouHuidong Shi

Abstract 2459: Adt-030 is a Novel Dual-Acting Ras/β-Catenin Inhibitor That Potentiates Antitumor Immunity. Cancer Research (2024)

Md Yeashin GaziOgacheko OkokoXin WangCaitlin BrandleXi ChenKhalda FadlallaAdam KeetonYulia MaxuitenkoCatherine HedrickHuidong ShiGary PiazzaGang Zhou

A Pan-Ras Inhibitor With a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer. Cancer Research (2024)

Calcium Nanoparticles Target and Activate T Cells to Enhance Anti-Tumor Function. Nature Communications (2024)

Wei YangZhizi FengXinning LaiJianwen LiZhengwei CaoFangchao JiangFanghui ChenShuyue ZhanFeng KongLi YangYong TengWendy T. WatfordGang ZhouJin Xie

Host-Derived Interleukin 1α Induces an Immunosuppressive Tumor Microenvironment via Regulating Monocyte-To-Macrophage Differentiation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Sara SiglerMohammad Abdel-HalimReem K. FathallaLuciana Madeira Da SilvaAdam B. KeetonYulia Y. MaxuitenkoKristy BerryGang ZhouMatthias EngelAshraf H. AbadiGary A. Piazza

Zhi-chun DingGeorge I. ZhouOgacheko D. OkokoXin WangLocke J. BryanGang ZhouHuidong Shi

transcriptomeneutrophil-like monocyte subsetsingle-cell analysismolecular biologymyeloid cellspro-tumor activitiessingle-cell transcriptome profilingcell biology

Abstract 1633: Adt-030, a Novel Dual-Acting Ras and β-Catenin Inhibitor With Robust Antitumor Activity. Cancer Research (2023)

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