Faculty

Institution

Unit

Venue

Gabriele Varani

Professor

University of Washington

Affiliations

College of Arts & Sciences

Department of Chemistry

Gabriele Varani is currently serving as a College Of Arts & Sciences Professor at University of Washington.

Honors

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Experiences

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Education

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Gabriele Varani

University of Washington

Professor

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molecular biology rna biology structural biology genetics biochemistry biophysics protein science nuclear magnetic resonance protein structure virology structural molecular biology gene expression hiv bioinformatics genome biology enzymes virus research nucleic acids biomolecular structure viral genetics general virology medicinal research gene regulation molecular science molecular virology biological chemistry antiviral research virus structure rna processing molecular regulation enzyme inhibition molecular structure gene structure structure determination non-coding rna solution structure structural bioinformatics viral replication transcription regulation pharmaceutical sciences rna structure rna recognition structural basis virus-host interactions gene function antiviral therapy conformational studies antiviral drug development tumor targeting molecular recognition enzyme specificity rna-binding proteins tat protein clinical microbiology nuclear magnetic resonance spectroscopy drug targeting human retrovirus structural genomics long non-coding rna viral structural protein nmr structure chemical sciences biopolymers molecular design dna analysis biomolecular analysis nmr studies ethidium bromide rna-protein recognition hiv tar rna experimental biophysics nmr spectroscopy n-terminal rnp domain regulatory element specific recognition virus rna promoter biophysical chemistry physical chemistry chemistry general chemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Small Molecules Targeting Micrornas: New Opportunities and Challenges in Precision Cancer Therapy. Trends in cancer (2024)

Ancuta JurjBeatrice FontanaGabriele VaraniGeorge A. Calin

non-coding rnatumor targetingtumor biologylong non-coding rnasmall rnamicrorna detectionsmall moleculescancer researchcancer discoverymolecular biologytherapeutic targetsprecision cancer therapyoncology

Structure of Essential Rna Regulatory Elements in the West Nile Virus 3’-Terminal Stem Loop. Journal of Molecular Biology (2024)

Ying ZhuBhawna ChaubeyGregory L. OlsenGabriele Varani

virologyvirus structuregene structuremolecular biologymolecular structurestructural biologyvirus research

Structure of West Nile Virus 3'-Terminal Stem-Loop: A Highly Conserved Element Essential for Flavivirus Replication. (2024)

Ying ZhuBhawna ChaubeyGregory L. OlsenGabriele Varani

viral structural proteinviral replicationvirologyviral geneticsflavivirus replicationvirus structuremicrobiologymolecular biologyviral evolutiongeneral virologystructural biologygenetics

Drug-Like Small Molecules That Inhibit Expression of the Oncogenic Microrna-21. ACS Chemical Biology (2023)

Matthew D. ShortridgeBhawna ChaubeyHuanyu J. ZhangThomas PavelitzVenkata VidadalaChangyan TangGregory L. OlsenGeorge A. CalinGabriele Varani

tumor biologymedicinal chemistrymolecular biologypharmacologygene expressionrna biologyoncologydrug-like small molecules

Two Distinct Binding Modes Provide the Rna-Binding Protein Rbfox With Extraordinary Sequence Specificity. Nature Communications (2023)

Xuan YeWen YangSoon YiYanan ZhaoGabriele VaraniEckhard JankowskyFan Yang

biophysicsprotein sciencebiochemistryrna-binding protein rbfoxmolecular biologyrna biologybioinformatics

A Functional Snp Regulates E-Cadherin Expression by Dynamically Remodeling the 3D Structure of a Promoter-Associated Non-Coding Rna Transcript. Nucleic Acids Research (2022)

Shrikant SharmaGiuseppina PisignanoJessica MerullaCarlo V CatapanoGabriele Varani

e-cadherin expressionmolecular geneticsfunctional snpgeneticsgenomicsmolecular scienceepigenomicstranscription regulationmolecular biologygene expressiontranslational bioinformaticsbiomolecular structurenucleic acidssystems biologyrna biologystructural biologygenome biologyprotein sciencemembrane biologymolecular regulation

A Slow Dynamic Rna Switch Regulates Processing of Microrna-21. Journal of Molecular Biology (2022)

Matthew D. ShortridgeGreg L. OlsenWen YangMatthew J. WalkerGabriele Varani

rna processinggene regulationmolecular regulationmolecular biologysignal transductionrna biologygenetics

Structure of the Dengue Virus Rna Promoter. RNA (2022)

Yi-Ting SunGabriele Varani

viral geneticsvirologyvirus structuremicrobiologygene structuremolecular biologymolecular virologygeneral virologyrna biologystructural biologygeneticsvirus research

The Kinase Inhibitor Palbociclib is a Potent and Specific Rna-Binding Molecule. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Matthew D. ShortridgeVenkata VidalalaGabriele Varani

enzymesbiochemistrymedicinal chemistrypharmacologymolecular biologymolecular pharmacologydrug discoverykinase inhibitor palbociclibenzyme inhibitionrna biology

Efficient Nmr Screening Approach to Discover Small Molecule Fragments Binding Structured Rna. ACS Medicinal Chemistry Letters (2021)

Matthew D. ShortridgeGabriele Varani

small molecule fragmentsmedicinal chemistryefficient nmrmedicinepharmacologymolecular biologydrug discoverynuclear magnetic resonancerna biology

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Gabriele Varani

Professor

University of Washington

Affiliations

College of Arts & Sciences

Department of Chemistry

Gabriele Varani is currently serving as a College Of Arts & Sciences Professor at University of Washington.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Gabriele Varani

University of Washington

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Small Molecules Targeting Micrornas: New Opportunities and Challenges in Precision Cancer Therapy. Trends in cancer (2024)

Ancuta JurjBeatrice FontanaGabriele VaraniGeorge A. Calin

Structure of Essential Rna Regulatory Elements in the West Nile Virus 3’-Terminal Stem Loop. Journal of Molecular Biology (2024)

Ying ZhuBhawna ChaubeyGregory L. OlsenGabriele Varani

virologyvirus structuregene structuremolecular biologymolecular structurestructural biologyvirus research

Structure of West Nile Virus 3'-Terminal Stem-Loop: A Highly Conserved Element Essential for Flavivirus Replication. (2024)

Ying ZhuBhawna ChaubeyGregory L. OlsenGabriele Varani

viral structural proteinviral replicationvirologyviral geneticsflavivirus replicationvirus structuremicrobiologymolecular biologyviral evolutiongeneral virologystructural biologygenetics

Drug-Like Small Molecules That Inhibit Expression of the Oncogenic Microrna-21. ACS Chemical Biology (2023)

Matthew D. ShortridgeBhawna ChaubeyHuanyu J. ZhangThomas PavelitzVenkata VidadalaChangyan TangGregory L. OlsenGeorge A. CalinGabriele Varani

tumor biologymedicinal chemistrymolecular biologypharmacologygene expressionrna biologyoncologydrug-like small molecules

Two Distinct Binding Modes Provide the Rna-Binding Protein Rbfox With Extraordinary Sequence Specificity. Nature Communications (2023)

Xuan YeWen YangSoon YiYanan ZhaoGabriele VaraniEckhard JankowskyFan Yang

biophysicsprotein sciencebiochemistryrna-binding protein rbfoxmolecular biologyrna biologybioinformatics

A Functional Snp Regulates E-Cadherin Expression by Dynamically Remodeling the 3D Structure of a Promoter-Associated Non-Coding Rna Transcript. Nucleic Acids Research (2022)

Shrikant SharmaGiuseppina PisignanoJessica MerullaCarlo V CatapanoGabriele Varani

A Slow Dynamic Rna Switch Regulates Processing of Microrna-21. Journal of Molecular Biology (2022)

Matthew D. ShortridgeGreg L. OlsenWen YangMatthew J. WalkerGabriele Varani

rna processinggene regulationmolecular regulationmolecular biologysignal transductionrna biologygenetics

Structure of the Dengue Virus Rna Promoter. RNA (2022)

Yi-Ting SunGabriele Varani

viral geneticsvirologyvirus structuremicrobiologygene structuremolecular biologymolecular virologygeneral virologyrna biologystructural biologygeneticsvirus research

The Kinase Inhibitor Palbociclib is a Potent and Specific Rna-Binding Molecule. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Matthew D. ShortridgeVenkata VidalalaGabriele Varani

enzymesbiochemistrymedicinal chemistrypharmacologymolecular biologymolecular pharmacologydrug discoverykinase inhibitor palbociclibenzyme inhibitionrna biology

Efficient Nmr Screening Approach to Discover Small Molecule Fragments Binding Structured Rna. ACS Medicinal Chemistry Letters (2021)

Matthew D. ShortridgeGabriele Varani

small molecule fragmentsmedicinal chemistryefficient nmrmedicinepharmacologymolecular biologydrug discoverynuclear magnetic resonancerna biology

1
2
3
4
5
36
10 / page

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