Faculty

Institution

Unit

Venue

Frank Nichols

Professor

University of Connecticut

Affiliations

School of Dental Medicine

Periodontology

Frank Nichols is currently serving as a Periodontology Professor at University of Connecticut.

Honors

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Experiences

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Education

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Frank Nichols

University of Connecticut

Professor

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immunology pharmacology microbiology oral biology clinical microbiology dermatology lipids membrane biology periodontology immune responses porphyromonas gingivalis oral health oral medicine infection control clinical research microbial pathogenesis gene expression vascular biology lipid analysis bacteria lipid science human monocytes veterinary medicine bone research applied microbiology bacteriology oral microbiology bacterial lipopolysaccharide clinical lipidology endodontics adaptive immune system lipid chemistry host response molecular microbiology liver physiology cellular physiology biogerontology viral pathogenesis bone metabolism cell regulation plant physiology biochemical sciences membrane science cell death innate immune system clinical immunology phytochemistry lipid preparation bone health bone homeostasis microbial physiology osmoregulation veterinary microbiology clinical dentistry apoptosis cellular biology t-regulatory cell serine dipeptide lipids phosphoglycerol dihydroceramide lipid extracts molecular pathology release mechanism mechanisms of action receptor (biochemistry) hyperlipidemia dermal structure calcium hydroxide biological properties calcium hydroxide treatment tnf-a signaling microbiome-associated biomarker bacterial lipodipeptide lps-elicited secretory responses adult periodontitis altered release generalized refractory periodontitis dentistry epidemiology periodontal diseases clinical periodontology dental implants primary care dentistry oral hygiene

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dementia Exacerbates Periodontal Bone Loss in Females. Journal of Periodontal Research (2024)

Chiaki YamadaAnny HoChristopher GarciaAdrian L. OblakStephanie BisselTatiana PorosencovaEgor PorosencovDiana UncutaBidii NgalaDmytro ShepilovGalyna SkiboAna Karina MascarenhasJuliet AkkaouiMadepalli K. LakshmanaUma SankarFrank NicholsBruce T. LambStanislav GroppaAlexandru Movila

periodontal bone losswomen's healthperiodontologydementiahealth sciences

Inhibition of Sars-Cov-2 Infection by Porphyromonas Gingivalis and the Oral Microbiome. Microbiology Spectrum (2024)

Alexander BontempoAlexandra ChirinoAlireza HeidariAlexandra LugoSatoru ShindoMaria R. PastoreRiccardo MadoniaSibel A. AntonsonCristina GodoyFrank C. NicholsJan PotempaMary Ellen DaveyToshihisa KawaiMark J. Cayabyab

clinical microbiologyinfectious diseaseshost-microbe interactionsmicrobiologysars-cov-2oral microbiomecovid-19oral microbiologymicrobiomeinfection controlvirus research

Microbiome-Derived Bacterial Lipids Regulate Gene Expression of Proinflammatory Pathway Inhibitors in Systemic Monocytes. Frontiers in Immunology (2024)

Saki MihoriFrank NicholsAnthony ProvatasAlyssa MatzBeiyan ZhouChristopher N. BlessoHunter PanierLauren DaddiYanjiao ZhouRobert B. Clark

clinical microbiologyinflammationproinflammatory pathway inhibitorsimmunologydermatologymicrobiologysystemic monocytesmicrobiome-derived bacterial lipidsgene expressionmicrobiome

The Multifaceted Role of C-DI-Amp Signaling in the Regulation of Porphyromonas Gingivalis Lipopolysaccharide Structure and Function. Frontiers in Cellular and Infection Microbiology (2024)

Shirin GhodsArtur MuszyńskiHyojik YangRatnam S. SeelanAsal MohammadiJacob S. HilsonGriffin KeiserFrank C. NicholsParastoo AzadiRobert K. ErnstFata Moradali

molecular and cellular biologybiomolecular interactionscell and molecular biologyclinical microbiologycarbohydrate-protein interactionscell signalingcell biologyc-di-amp signalingmolecular biologymultifaceted rolebiochemical interactioncarbohydrate chemistryinfection controlcellular physiologysignaling pathwaysmicrobiologyfood microbiologyapplied microbiologymolecular microbiologymembrane biology

Dihydroceramides Derived From Bacteroidetes Species Sensitize Trpv1 Channels. International Journal of Molecular Sciences (2023)

Nora LudwigIsaac S. DemareeChiaki YamadaAmilia NusbaumFrank C. NicholsFletcher A. WhiteAlexandru MovilaAlexander G. Obukhov

microbiologybacteriamolecular biologybiomolecular engineeringbacteroidetes species

Expression of the 2Duf Protein in Wild-Type Bacillus Subtilis Spores Stabilizes Inner Membrane Proteins and Increases Spore Resistance to Wet Heat and Hydrogen Peroxide. Journal of Applied Microbiology (2023)

George KorzaSarah DePrattiDaniel FairchildJames WicanderJulia KanaanHannah ShamesFrank C NicholsAnn CowanStanley BrulPeter Setlow

hydrogen peroxidemolecular microbiologymicrobial physiologymicrobiologybacteriabacillus subtilisbacteriologygene expressionapplied microbiologyhost-microbe interactions

Harnessing the Microbiome to Regulate Systemic Innate Immunity. The Journal of Immunology (2023)

Saki MihoriFrank NicholsAnthony ProvatasChristopher N BlessoRobert B Clark

immunologymicrobiomesystemic innate immunity

Identification and Characterization of New Proteins Crucial for Bacterial Spore Resistance and Germination. Frontiers in Microbiology (2023)

Benjamin YuJulia KanaanHannah ShamesJames WicanderMakunda AryalYunfeng LiGeorge KorzaStanley BrulGertjan KramerYong-qing LiFrank C. NicholsBing HaoPeter Setlow

microbiologybacteriabacteriologybacterial spore resistance

Inhibitory Effect of Porphyromonas Gingivalis ‐Derived Phosphoethanolamine Dihydroceramide on Acid Ceramidase Expression in Oral Squamous Cells. Journal of Cellular and Molecular Medicine (2023)

Chiaki YamadaAnny HoAmilia NusbaumRuijuan XuMary Ellen DaveyFrank NicholsCungui MaoAlexandru Movila

molecular and cellular biologyoral squamous cellsphosphoethanolamine dihydroceramidephysiologyacid ceramidase expressionoral medicinecell biologymedicinal chemistryoral biologymembrane biologycellular biologypharmacologyinhibitory effect

In Situ Raman Study of Neurodegenerated Human Neuroblastoma Cells Exposed to Outer-Membrane Vesicles Isolated From Porphyromonas Gingivalis. International Journal of Molecular Sciences (2023)

Giuseppe PezzottiTetsuya AdachiHayata ImamuraDavide Redolfi BristolKeiji AdachiToshiro YamamotoNarisato KanamuraElia MarinWenliang ZhuToshihisa KawaiOsam MazdaToru KariuTomonori WakuFrank C. NicholsPietro RielloFlavio RizzolioTania LimongiKazu Okuma

porphyromonas gingivalissurface scienceraman spectroscopyneurosciencemolecular biologyouter-membrane vesicles

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Frank Nichols

Professor

University of Connecticut

Affiliations

School of Dental Medicine

Periodontology

Frank Nichols is currently serving as a Periodontology Professor at University of Connecticut.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Frank Nichols

University of Connecticut

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dementia Exacerbates Periodontal Bone Loss in Females. Journal of Periodontal Research (2024)

periodontal bone losswomen's healthperiodontologydementiahealth sciences

Inhibition of Sars-Cov-2 Infection by Porphyromonas Gingivalis and the Oral Microbiome. Microbiology Spectrum (2024)

clinical microbiologyinfectious diseaseshost-microbe interactionsmicrobiologysars-cov-2oral microbiomecovid-19oral microbiologymicrobiomeinfection controlvirus research

Microbiome-Derived Bacterial Lipids Regulate Gene Expression of Proinflammatory Pathway Inhibitors in Systemic Monocytes. Frontiers in Immunology (2024)

Saki MihoriFrank NicholsAnthony ProvatasAlyssa MatzBeiyan ZhouChristopher N. BlessoHunter PanierLauren DaddiYanjiao ZhouRobert B. Clark

clinical microbiologyinflammationproinflammatory pathway inhibitorsimmunologydermatologymicrobiologysystemic monocytesmicrobiome-derived bacterial lipidsgene expressionmicrobiome

The Multifaceted Role of C-DI-Amp Signaling in the Regulation of Porphyromonas Gingivalis Lipopolysaccharide Structure and Function. Frontiers in Cellular and Infection Microbiology (2024)

Shirin GhodsArtur MuszyńskiHyojik YangRatnam S. SeelanAsal MohammadiJacob S. HilsonGriffin KeiserFrank C. NicholsParastoo AzadiRobert K. ErnstFata Moradali

Dihydroceramides Derived From Bacteroidetes Species Sensitize Trpv1 Channels. International Journal of Molecular Sciences (2023)

Nora LudwigIsaac S. DemareeChiaki YamadaAmilia NusbaumFrank C. NicholsFletcher A. WhiteAlexandru MovilaAlexander G. Obukhov

microbiologybacteriamolecular biologybiomolecular engineeringbacteroidetes species

George KorzaSarah DePrattiDaniel FairchildJames WicanderJulia KanaanHannah ShamesFrank C NicholsAnn CowanStanley BrulPeter Setlow

hydrogen peroxidemolecular microbiologymicrobial physiologymicrobiologybacteriabacillus subtilisbacteriologygene expressionapplied microbiologyhost-microbe interactions

Harnessing the Microbiome to Regulate Systemic Innate Immunity. The Journal of Immunology (2023)

Saki MihoriFrank NicholsAnthony ProvatasChristopher N BlessoRobert B Clark

immunologymicrobiomesystemic innate immunity

Identification and Characterization of New Proteins Crucial for Bacterial Spore Resistance and Germination. Frontiers in Microbiology (2023)

Benjamin YuJulia KanaanHannah ShamesJames WicanderMakunda AryalYunfeng LiGeorge KorzaStanley BrulGertjan KramerYong-qing LiFrank C. NicholsBing HaoPeter Setlow

microbiologybacteriabacteriologybacterial spore resistance

Inhibitory Effect of Porphyromonas Gingivalis ‐Derived Phosphoethanolamine Dihydroceramide on Acid Ceramidase Expression in Oral Squamous Cells. Journal of Cellular and Molecular Medicine (2023)

Chiaki YamadaAnny HoAmilia NusbaumRuijuan XuMary Ellen DaveyFrank NicholsCungui MaoAlexandru Movila

In Situ Raman Study of Neurodegenerated Human Neuroblastoma Cells Exposed to Outer-Membrane Vesicles Isolated From Porphyromonas Gingivalis. International Journal of Molecular Sciences (2023)

porphyromonas gingivalissurface scienceraman spectroscopyneurosciencemolecular biologyouter-membrane vesicles

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University of California, Los Angeles

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University of Florida

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molecular medicine

Hatice Hasturk

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Hatice Hasturk

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Richard P. Darveau

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innate immune system

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