Faculty

Institution

Unit

Venue

Hangzhong Feng

Research Assistant Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

Hangzhong Feng is currently serving as a College Of Medicine Research Assistant Professor at University of Illinois Chicago.

Honors

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Experiences

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Education

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Hangzhong Feng

University of Illinois Chicago

Research Assistant Professor

You can click a keyword to filter the displayed items

physiology cardiology mammalian biology cellular physiology animal physiology genetics cell biology pharmacology protein science skeletal muscle applied physiology molecular physiology mammalian physiology gene expression membrane biology exercise physiology biomechanics muscle function cardiovascular research cardiac muscle neurophysiology electrophysiology cardiovascular physiology circulatory physiology human physiology cell physiology endocrinology vascular biology physiological research cardiomyopathy tissue physiology animal science molecular regulation protein function cardiovascular function musculoskeletal science biological chemistry peptides experimental medicine cardiovascular pharmacology protein expression clinical physiology blood pressure medical genetics carbonic anhydrase iii n-terminal truncation cardiovascular interventions peptide science comparative physiology veterinary physiology protein evolution translational physiology knockout mice physiological regulation orthopedic biomechanics musculoskeletal function muscle mass insulin resistance transgenic expression mouse skeletal muscles fatigue resistance energetic crisis enzyme inhibition functional modification catalyst activation cerebrovascular disease preventive cardiology gene structure cardiomyocyte molecular clock arrhythmia susceptibility functional adaptation novel mechanism nebulin-related myopathy cardiac contraction rad gtpase deletion l-type calcium channel muscular dystrophies muscle contractions systems biology myositis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Potential Cytotoxicity of Truncated Slow Skeletal Muscle Troponin T ( Sstnt ) in a Loss of Function Tnnt1 Myopathy Mouse Model. FEBS Journal (2025)

pathologymyositisphysiologymuscle functioncell biologycellular physiologypotential cytotoxicityskeletal musclemuscular dystrophiesmusculoskeletal disorderstissue (biology)

The Highly Conserved C-Terminal End Segment of Troponin T Binds Tropomyosin and Actin to Function in Modulating Contractile Kinetics. Proceedings of the National Academy of Sciences (2025)

molecular and cellular biologycontractile kineticscell signalingcell biologycellular physiologycellular structurec-terminal end segmentmolecular physiologycytoskeletonmolecular motorsmolecular cell biologymolecular biologytroponin tcell motilitysignal transductionstructural molecular biologycellular biochemistry

Biomechanical Evaluation of Flash-Frozen and Cryo-Sectioned Papillary Muscle Samples by Using Sinusoidal Analysis: Cross-Bridge Kinetics and the Effect of Partial Ca2+ Activation. Journal of Muscle Research and Cell Motility (2024)

Jing XiHan-Zhong FengJian-Ping JinJinxiang YuanMasataka Kawai

cross-bridge kineticsphysiologysinusoidal analysisbiomechanical evaluationcell motilitybiomechanics

Phenotypes of Mice Expressing a Myopathic Exon 8 Deletion Mutant of Slow Skeletal Muscle Troponin T Reveal Novel Pathogenic and Pathophysiological Mechanism. Biophysical Journal (2024)

Han-Zhong FengJ.-P. Jin

exercise physiologydisease pathophysiologydeletion mutantimmunopathologymuscle functionimmunologygeneticsanimal physiologypathogenesispathogensmolecular biologygene expressionpathophysiological mechanismcellular physiologyskeletal musclemusculoskeletal disordersprotein sciencemembrane biologymammalian biologygenetic basis

Studies of Ca2+-Activated Contractility Using Skinned Cryosections of Human Ventricular Papillary Muscle Samples From Frozen Storage of Discarded Clinical Specimens Collected in Biorepository. Biophysical Journal (2024)

Han-Zhong FengMilburn Gregory MilburnKenneth S. CampbellJian-Ping Jin

neurosciencetissue physiologyneurophysiologyfrozen storagecirculatory physiologyphysiologydiscarded clinical specimensphysiological measurementsapplied physiologycardiovascular physiologycardiologycellular physiologyexperimental biophysicsskinned cryosectionsbiophysicsmedical biophysicsregenerative medicineelectrophysiologymembrane biologyclinical physiology

Conditionally Dominant Negative Impacts of Clinically Recessive Tnnt1 Myopathy Mutations. Biophysical Journal (2023)

Han-Zhong FengJian-Ping Jin

biophysicsgenetic disordersdisparate impactdominant negative impactsmolecular geneticsmedical geneticsmolecular biologyhuman geneticsgene expressioncancer geneticsgenetics

Glu-Rich N-Terminal Variable Region of Troponin T Functions as a Myofilament Ca2+-Reservoir to Reduce Sr Ca2+-Cycling. Biophysical Journal (2023)

myofilament ca2+-reservoirphysiologytroponin t functionscellular physiologybiochemistrymolecular physiologycytoskeletonsr ca2+-cyclingsignal transduction

N-Terminal Truncated Cardiac Troponin I Enhances Frank-Starling Response by Increasing Myofilament Sensitivity to Resting Tension. The Journal of General Physiology (2023)

Han-Zhong FengXupei HuangJian-Ping Jin

cardiologyphysiologyelectrophysiologymyofilament sensitivitystress (biology)pharmacologyfrank-starling response

The Conserved C-Terminal End Segment of Troponin T is a New Tropomyosin-Binding Site Modulating the Kinetics of Cardiac Muscle. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Tianxin CaoHan-Zhong FengJ.-P. Jin

liver physiologymuscle functionphage biologyc-terminal end segmentcirculatory physiologyphysiologymolecular biologyprotein foldingcardiac muscleprotein biosynthesiscardiologymembrane proteinscellular physiologyendocrinologytissue (biology)in vitro toxicologybiophysicsmolecular physiologystructure-function enzyme kinetics

The C-Terminal End Segment of Troponin T is a Novel Tropomyosin-Binding Site Directly Regulated by Ca2+ to Determine the Kinetics of Cardiac Muscle. Biophysical Journal (2023)

Tianxin CaoHan-Zhong FengJian-Ping Jin

muscle functionc-terminal end segmentbiotransformationbiophysical chemistryphysiologybiophysical reviewcell biologymolecular biophysicscardiac musclecardiologymembrane proteinscellular physiologyexperimental biophysicsbioenergeticsbiophysicsmedical biophysicsprotein sciencemolecular physiologysignal transduction

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Hangzhong Feng

Research Assistant Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

Hangzhong Feng is currently serving as a College Of Medicine Research Assistant Professor at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Hangzhong Feng

University of Illinois Chicago

Research Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Potential Cytotoxicity of Truncated Slow Skeletal Muscle Troponin T ( Sstnt ) in a Loss of Function Tnnt1 Myopathy Mouse Model. FEBS Journal (2025)

pathologymyositisphysiologymuscle functioncell biologycellular physiologypotential cytotoxicityskeletal musclemuscular dystrophiesmusculoskeletal disorderstissue (biology)

The Highly Conserved C-Terminal End Segment of Troponin T Binds Tropomyosin and Actin to Function in Modulating Contractile Kinetics. Proceedings of the National Academy of Sciences (2025)

Jing XiHan-Zhong FengJian-Ping JinJinxiang YuanMasataka Kawai

cross-bridge kineticsphysiologysinusoidal analysisbiomechanical evaluationcell motilitybiomechanics

Phenotypes of Mice Expressing a Myopathic Exon 8 Deletion Mutant of Slow Skeletal Muscle Troponin T Reveal Novel Pathogenic and Pathophysiological Mechanism. Biophysical Journal (2024)

Han-Zhong FengJ.-P. Jin

Han-Zhong FengMilburn Gregory MilburnKenneth S. CampbellJian-Ping Jin

Conditionally Dominant Negative Impacts of Clinically Recessive Tnnt1 Myopathy Mutations. Biophysical Journal (2023)

Han-Zhong FengJian-Ping Jin

biophysicsgenetic disordersdisparate impactdominant negative impactsmolecular geneticsmedical geneticsmolecular biologyhuman geneticsgene expressioncancer geneticsgenetics

Glu-Rich N-Terminal Variable Region of Troponin T Functions as a Myofilament Ca2+-Reservoir to Reduce Sr Ca2+-Cycling. Biophysical Journal (2023)

myofilament ca2+-reservoirphysiologytroponin t functionscellular physiologybiochemistrymolecular physiologycytoskeletonsr ca2+-cyclingsignal transduction

N-Terminal Truncated Cardiac Troponin I Enhances Frank-Starling Response by Increasing Myofilament Sensitivity to Resting Tension. The Journal of General Physiology (2023)

Han-Zhong FengXupei HuangJian-Ping Jin

cardiologyphysiologyelectrophysiologymyofilament sensitivitystress (biology)pharmacologyfrank-starling response

The Conserved C-Terminal End Segment of Troponin T is a New Tropomyosin-Binding Site Modulating the Kinetics of Cardiac Muscle. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Tianxin CaoHan-Zhong FengJ.-P. Jin

The C-Terminal End Segment of Troponin T is a Novel Tropomyosin-Binding Site Directly Regulated by Ca2+ to Determine the Kinetics of Cardiac Muscle. Biophysical Journal (2023)

Tianxin CaoHan-Zhong FengJian-Ping Jin

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Similar Faculty Members

Kenneth S. Campbell

Institution

University of Kentucky

physiology

cardiology

Jian-Ping Jin

Institution

University of Illinois Chicago

developmental biology

muscle cell motility

Jian-Ping Jin

Institution

Wayne State University

mechanical tension regulation

protein structure-function relationships

Sandor Gyorke

Institution

Ohio State University

laboratory investigation

tissue (biology)

Aldrin V. Gomes

Institution

University of California, Davis

protein homeostasis

metabolism

Luis Fernando Santana

Institution

University of California, Davis

cerebral arteries

cerebral blood flow

Nipavan Chiamvimonvat

Institution

University of Arizona

circulatory physiology

electrophysiology

Mansoureh Eghbali

Institution

University of California, Los Angeles

respiratory medicine

cardiovascular disease

William A. Coetzee

Institution

New York University

cardiovascular disease

cardiovascular biology

Bjorn C. Knollmann

Institution

Vanderbilt University

electrophysiological evaluation

cardiovascular disease