Faculty

Institution

Unit

Venue

Eric R Fearon

Professor

University of Michigan

Affiliations

Michigan Medical School

Human Genetics

Eric R Fearon is currently serving as a Human Genetics Professor at University of Michigan.

Honors

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Experiences

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Education

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Eric R Fearon

University of Michigan

Professor

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cancer biology oncology cancer research tumor biology molecular biology genetics cancer genetics oncogenes gene expression colorectal cancer cell biology pathology cancer cells carcinogenesis molecular cancer medicinal research cancer genomics cell signaling tumor suppressors cancer discovery signal transduction vascular biology tumor microenvironment gynecologic oncology cancer growth signaling pathways gastrointestinal oncology molecular gastroenterology gene function histopathology biological chemistry cancer care mouse model genome biology mammalian biology molecular cell biology cytogenetics transcription regulation clinical pathology pancreatic cancer tumor targeting cancer treatment stem cell research cell regulation colon cancer protein science molecular regulation gene regulation breast oncology medical genetics chromosome biology molecular pathology cancer risk tumoral pathology colorectal tumorigenesis genitourinary cancers hematological malignancies cancer management cellular biology ovarian endometrioid adenocarcinomas endocrine-related cancers liver cancer pathway analysis malignant disease colorectal carcinomas clonal analysis neoplastic transformation carrier detection e-cadherin expression dcc expression genetic alterations cancer stem cells human cancer acute nonlymphocytic leukemia downstream target human cancers

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 4752: Hmga1: An Epigenetic Driver of Colon Carcinogenesis by Inducing Fgf19 Signals Which Can Be Targeted With Fgfr4 Receptor Blockade. Cancer Research (2026)

oncogenescolorectal cancerepigeneticscell biologycarcinogenesis

Colon-Restricted Phosphatase and Tensin Homolog Deleted From Chromosome 10 Haploinsufficiency Models Phosphoinositide 3-Kinase Pathway-Driven Invasion in Colorectal Cancer. Cellular and Molecular Gastroenterology and Hepatology (2026)

molecular and cellular biologyoncogenespathologycancer cellstumor biologycolorectal cancercell signalingcell biologymolecular cancermolecular cell biologymolecular gastroenterologysignal transduction

A P53 Peptide Mucosal Vaccine Induces Cellular and Humoral Immunity and Anti-Tumor Effects in a Murine Colorectal Cancer Model. Cancer Gene Therapy (2025)

colorectal cancercancer immunotherapyimmunologycell biologyimmunotherapycellular therapyimmunomodulationimmune responses

Bilateral Salpingo-Oophorectomy is Superior to Salpingectomy Alone in Preventing Non-Tubal Tumor Development in a Mouse Model of High-Grade Serous Carcinoma. Cancers (2025)

gynecologic oncologypathologysurgerysurgical oncologysurgical pathologygynecologic cancersgynecological surgeryoncology

Defining Cdk12 as a Tumor Suppressor and Therapeutic Target in Mouse Models of Tubo-Ovarian High-Grade Serous Carcinoma. Proceedings of the National Academy of Sciences (2025)

gynecologic oncologypathologytumor biologycell biologytumor suppressorsgynecologic cancersovarian cancercancer biology

Hmga1 Acts as an Epigenetic Gatekeeper of Ascl2 and Wnt Signaling During Colon Tumorigenesis. Journal of Clinical Investigation (2025)

oncogenescolorectal cancerpathologycell signalingepigeneticscell biologycarcinogenesis

Sox9 Suppresses Colon Cancer via Inhibiting Epithelial-Mesenchymal Transition and Sox2 Induction. Journal of Clinical Investigation (2025)

oncogenescolorectal cancertumor biologycell biologymolecular cancercancer cells

Abstract 1259: Hmga1: An Epigenetic Gatekeeper of Wnt Signals During Colon Tumorigenesis and Regeneration. Cancer Research (2024)

Linda M. S. ResarLi Z. LuoLingling XianIliana HerreraShaoguang WuJung-Hyun KimYing FengJulian Calderon-EspinosaEric R. FearonCynthia Sears

colorectal cancerepigenetic gatekeepertumor biologyepigeneticscancer researchcolon tumorigenesishealth sciencesoncologycancer biologywnt signals

Abstract 4101: Immune Inhibition of Murine Colorectal Cancer by a P53 Peptide Mucosal Vaccine. Cancer Research (2024)

Suhe WangZhengyi CaoKatarzyna W. JanczakYing FengMaranne GreenEric R. FearonJames R. Baker Jr

mucosal vaccinationcolorectal cancervaccinescancer immunotherapyimmunologyimmune inhibitioncancer researchmucosal immunologymurine colorectal cancer

Ccn6 Suppresses Metaplastic Breast Carcinoma by Antagonizing Wnt/β-Catenin Signaling to Inhibit Ezh2-Driven Emt. Cancer Research (2024)

Maria E. GonzalezBryce BrophyAhmad EidoAdele E. LeonettiSabra I. DjomehriGiuseppina AugimeriNicholas J. CarruthersRaymond G. CavalcanteFrancesca GiordanoSebastiano AndòAlexey I. NesvizhskiiEric R. FearonCelina G. Kleer

breast oncologypathologycancer discoverybreast cancertumor biologycell biologycancer researchtumor suppressorsmolecular biologycancer cellscancer treatmentoncogenesmetaplastic breast carcinomamolecular cancertumor microenvironmentcancer biologytumor targetingcancer imagingoncology

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Eric R Fearon

Professor

University of Michigan

Affiliations

Michigan Medical School

Human Genetics

Eric R Fearon is currently serving as a Human Genetics Professor at University of Michigan.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Eric R Fearon

University of Michigan

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 4752: Hmga1: An Epigenetic Driver of Colon Carcinogenesis by Inducing Fgf19 Signals Which Can Be Targeted With Fgfr4 Receptor Blockade. Cancer Research (2026)

oncogenescolorectal cancerepigeneticscell biologycarcinogenesis

molecular and cellular biologyoncogenespathologycancer cellstumor biologycolorectal cancercell signalingcell biologymolecular cancermolecular cell biologymolecular gastroenterologysignal transduction

A P53 Peptide Mucosal Vaccine Induces Cellular and Humoral Immunity and Anti-Tumor Effects in a Murine Colorectal Cancer Model. Cancer Gene Therapy (2025)

colorectal cancercancer immunotherapyimmunologycell biologyimmunotherapycellular therapyimmunomodulationimmune responses

Bilateral Salpingo-Oophorectomy is Superior to Salpingectomy Alone in Preventing Non-Tubal Tumor Development in a Mouse Model of High-Grade Serous Carcinoma. Cancers (2025)

gynecologic oncologypathologysurgerysurgical oncologysurgical pathologygynecologic cancersgynecological surgeryoncology

Defining Cdk12 as a Tumor Suppressor and Therapeutic Target in Mouse Models of Tubo-Ovarian High-Grade Serous Carcinoma. Proceedings of the National Academy of Sciences (2025)

gynecologic oncologypathologytumor biologycell biologytumor suppressorsgynecologic cancersovarian cancercancer biology

Hmga1 Acts as an Epigenetic Gatekeeper of Ascl2 and Wnt Signaling During Colon Tumorigenesis. Journal of Clinical Investigation (2025)

oncogenescolorectal cancerpathologycell signalingepigeneticscell biologycarcinogenesis

Sox9 Suppresses Colon Cancer via Inhibiting Epithelial-Mesenchymal Transition and Sox2 Induction. Journal of Clinical Investigation (2025)

oncogenescolorectal cancertumor biologycell biologymolecular cancercancer cells

Abstract 1259: Hmga1: An Epigenetic Gatekeeper of Wnt Signals During Colon Tumorigenesis and Regeneration. Cancer Research (2024)

Linda M. S. ResarLi Z. LuoLingling XianIliana HerreraShaoguang WuJung-Hyun KimYing FengJulian Calderon-EspinosaEric R. FearonCynthia Sears

colorectal cancerepigenetic gatekeepertumor biologyepigeneticscancer researchcolon tumorigenesishealth sciencesoncologycancer biologywnt signals

Abstract 4101: Immune Inhibition of Murine Colorectal Cancer by a P53 Peptide Mucosal Vaccine. Cancer Research (2024)

Suhe WangZhengyi CaoKatarzyna W. JanczakYing FengMaranne GreenEric R. FearonJames R. Baker Jr

mucosal vaccinationcolorectal cancervaccinescancer immunotherapyimmunologyimmune inhibitioncancer researchmucosal immunologymurine colorectal cancer

Ccn6 Suppresses Metaplastic Breast Carcinoma by Antagonizing Wnt/β-Catenin Signaling to Inhibit Ezh2-Driven Emt. Cancer Research (2024)

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