Eric Gouaux

Oregon Health & Science University

Affiliations

OGI School of Science and Engineering

Department Of Chemistry, Biochemistry And Molecular Biology

Institute Of Vollum

NoneEric Gouaux is currently serving as a Chemistry, Biochemistry And Molecular Biology faculty at Oregon Health & Science University.

Honors

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Experiences

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Education

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Eric Gouaux

Oregon Health & Science University

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neuroscience structural biology neurology molecular biology pharmacology neuropharmacology receptors protein structure membrane biology neurophysiology molecular pharmacology mammalian biology neuropsychopharmacology affective neuroscience structural molecular biology protein science biomolecular structure pharmacological research dopamine neurobiological mechanisms inhibitory process neurotransmitters receptor (biochemistry) biomolecular interactions g protein-coupled receptor mechanisms of action glycine receptor mechanism electron cryo-microscopy allosteric inhibition stereocilia tip link central roles neurotransmitter dopamine human dopamine transporter cryo-em structures

Notable Scholarly Works

Notable Federal Grants

Collaborators

Structure of the Human Dopamine Transporter and Mechanisms of Inhibition. Nature (2024)

Dushyant Kumar SrivastavaVikas NavratnaDilip K. ToshAudrey ChinnMd Fulbabu SkEmad TajkhorshidKenneth A. JacobsonEric Gouaux

physiologyneurobiological mechanismsneuropsychopharmacologyhuman dopamine transporterinhibitory processneuropharmacologydopamineneurotransmittersneurotransmitter dopamineaffective neurosciencecentral rolesneuroscienceneurophysiology

Cryo-Em Structures Reveal Native Gaba a Receptor Assemblies and Pharmacology. Nature (2023)

g protein-coupled receptorbiomolecular interactionsreceptorspharmacologymechanisms of actionprotein structurecryo-em structuresmolecular pharmacologybiomolecular structurereceptor (biochemistry)molecular biologystructural molecular biologystructural biologyprotein sciencepharmacological researchbiochemistry

Hippocampal Ampa Receptor Assemblies and Mechanism of Allosteric Inhibition. Nature (2021)

Jie YuPrashant RaoSarah ClarkJaba MitraTaekjip HaEric Gouaux

neurologypharmacologyallosteric inhibitionneuropharmacologyneuroscience

Structure of Mouse Protocadherin 15 of the Stereocilia Tip Link in Complex With Lhfpl5. eLife (2018)

Jingpeng GeJohannes ElferichApril GoehringHuaying ZhaoPeter SchuckEric Gouaux

stereocilia tip linkprotein structuregeneticsmammalian biologystructural biologyneuroscience

Glycine Receptor Mechanism Elucidated by Electron Cryo-Microscopy. Nature (2015)

Juan DuWei LüShenping WuYifan ChengEric Gouaux

glycine receptor mechanismneurologyreceptorselectron cryo-microscopymolecular biologymembrane biologystructural biologyneuroscience