Faculty

Institution

Unit

Venue

Ellen Hoffman

Associate Professor

Yale University

Affiliations

Biological & Biomedical Sciences

Child Study Center

Neuroscience

Ellen Hoffman is currently serving as a Biological & Biomedical Sciences Associate Professor at Yale University.

Honors

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Experiences

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Education

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Ellen Hoffman

Yale University

Associate Professor

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genetics neuroscience neurogenetics autism neurodevelopmental disorders molecular biology genomics developmental neurobiology human genetics psychiatric genetics neurology molecular neuroscience autism spectrum disorder molecular neurodegeneration zebrafish models fish biology genetic disorders autism spectrum disorders genome biology biological psychiatry cytogenetics gene expression protein science medical genetics genetic factors developmental genetics zebrafish mutants cognitive neuroscience mammalian biology magnetic resonance psychopharmacology magnetic resonance spectroscopy cancer genetics clinical psychiatry clinical neuroscience brain circuitry obsessive-compulsive disorder pten mutations nature method animal behavior pharmacotherapy medicinal research neuroscience of aging animal science neuroradiology biomedical imaging cellular neurobiology biological inorganic chemistry protein assembly genomic mechanisms host response animal genetics genetic basis psychotropic medication clinical pharmacology clinical medicine neurochemistry in vivo systems opioid use disorder brain function functional regulation methanol signaling pathways neuroregeneration neurodynamics neural mechanisms coexpression networks context-dependent assembly selection-free zinc-finger-nuclease engineering rapid screening behavioral phenotype autism risk gene sporadic congenital hydrocephalus prenatal neuro-gliogenesis comprehensive review dna coding mutations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Brain-Wide Circuitry Underlying Altered Auditory Habituation in Zebrafish Models of Autism. Journal of Neuroscience (2026)

Maya WildeAnahita GhanbariTessa MancienneAilís MoranRebecca E PoulsenLena ConstantinConrad LeeLeandro Aluisio ScholzJoshua ArnoldWei QinTimothy J KarleSteven PetrouItia Favre-BulleEllen J HoffmanEthan K Scott

neuroscienceneurodevelopmental disordersauditory habituationzebrafish modelsautismbrain-wide circuitry

Estradiol Modulates Neuronal Network Hyperexcitability in Select Ndd Risk Genes. bioRxiv (Cold Spring Harbor Laboratory) (2026)

neurogeneticsneuroscienceneuronsmolecular neurodegenerationneuronal network hyperexcitabilitydevelopmental biologymolecular neurosciencepsychoneuroendocrinologyneuroendocrine mechanismsneurophysiologyneural circuitsneurodegenerative diseasesstructural plasticity

Pharmaco-Behavioral Profiling Identifies Suppressors of Autism Gene–Associated Phenotypes in Zebrafish. Proceedings of the National Academy of Sciences (2026)

geneticsbiological psychiatrymolecular psychiatrydevelopmental disordersgenetic factorsneurosciencesyndromic autismneurodevelopmental disordersdevelopmental biologybehavioural geneticsautismbehavioral neurosciencedevelopmental system

Transcriptomic and Phenotypic Convergence of Neurodevelopmental Disorder Risk Genes in Vitro and in Vivo. Nature Neuroscience (2026)

geneticshuman geneticsphenotypic convergencemolecular psychiatryneurogeneticsgenetic disordersneurosciencemolecular neurodegenerationneurodevelopmental disordersdevelopmental biologydisease gene identificationmolecular neurosciencedevelopmental neurobiology

Whole-Brain Cellular-Resolution Functional Network Properties of Seizure Susceptibility. bioRxiv (Cold Spring Harbor Laboratory) (2026)

neurologybrain circuitryneuroscienceneurophysiological biomarkersmolecular neurodegenerationseizure susceptibilityneurophysiologyneural circuitsepilepsy

24.1 Large-Scale Genetic and Pharmacological Screens in Zebrafish Identify Common Pathways Relevant to Asd. Journal of the American Academy of Child & Adolescent Psychiatry (2025)

gene functionmolecular psychiatrypharmacological screensneurogeneticslarge-scale geneticdevelopmental biologydevelopmental cellsystems biologydevelopmental neurobiologydevelopmental geneticsdevelopmental system

A Blueprint for Translational Precision Medicine in Autism Spectrum Disorder and Related Neurogenetic Syndromes. Journal of Child and Adolescent Psychopharmacology (2025)

Robyn P. ThomTracy L. WarrenSuha KhanRebecca A. MuhlePaul P. WangKristen BrennandNicole R. ZürcherJeremy Veenstra-VanderWeeleEllen J. Hoffman

autism spectrum disordermedicinepsychopharmacologytranslational precision medicineprecision medicinetranslational medicinerelated neurogenetic syndromes

Dynamic Convergence of Neurodevelopment Disorder Risk Genes: Seahorse Mito Stress and Mitochondrial Morphology Datasets. Zenodo (CERN European Organization for Nuclear Research) (2025)

geneticshuman geneticsabnormal developmentneurogeneticsdynamic convergencegenetic disordersgenetic factorsneurosciencemolecular neurodegenerationneurodevelopmental disordersmitochondrial morphology datasetsdevelopmental biologydisease gene identificationmolecular neurosciencedevelopmental neurobiologyseahorse mito stressdevelopmental geneticsdevelopmental system

Dynamic Convergence of Neurodevelopment Disorder Risk Genes: Zebrafish Baseline and Drug Behavioral Screen Dataset. Open MIND (2025)

biological psychiatryabnormal developmentpsychiatric geneticsneurogeneticsdynamic convergenceneurosciencedevelopmental cognitive neuroscienceneurodevelopmental disordersdevelopmental biologybehavioural geneticszebrafish baselinedevelopmental neurobiologybehavioral neuroscience

From the Bench to Bedside: Understanding the Pathogenesis of Asd. Journal of the American Academy of Child & Adolescent Psychiatry (2025)

disease progressionneuropathologymedicinetranslational researchcritical careinternal medicineevidence-based medicinedisease mechanismspathogenesis of asddegenerative diseaseclinical researchtranslational medicineexperimental medicineneurodegenerative diseases

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Ellen Hoffman

Associate Professor

Yale University

Affiliations

Biological & Biomedical Sciences

Child Study Center

Neuroscience

Ellen Hoffman is currently serving as a Biological & Biomedical Sciences Associate Professor at Yale University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ellen Hoffman

Yale University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Brain-Wide Circuitry Underlying Altered Auditory Habituation in Zebrafish Models of Autism. Journal of Neuroscience (2026)

neuroscienceneurodevelopmental disordersauditory habituationzebrafish modelsautismbrain-wide circuitry

Estradiol Modulates Neuronal Network Hyperexcitability in Select Ndd Risk Genes. bioRxiv (Cold Spring Harbor Laboratory) (2026)

Pharmaco-Behavioral Profiling Identifies Suppressors of Autism Gene–Associated Phenotypes in Zebrafish. Proceedings of the National Academy of Sciences (2026)

Transcriptomic and Phenotypic Convergence of Neurodevelopmental Disorder Risk Genes in Vitro and in Vivo. Nature Neuroscience (2026)

Whole-Brain Cellular-Resolution Functional Network Properties of Seizure Susceptibility. bioRxiv (Cold Spring Harbor Laboratory) (2026)

neurologybrain circuitryneuroscienceneurophysiological biomarkersmolecular neurodegenerationseizure susceptibilityneurophysiologyneural circuitsepilepsy

24.1 Large-Scale Genetic and Pharmacological Screens in Zebrafish Identify Common Pathways Relevant to Asd. Journal of the American Academy of Child & Adolescent Psychiatry (2025)

A Blueprint for Translational Precision Medicine in Autism Spectrum Disorder and Related Neurogenetic Syndromes. Journal of Child and Adolescent Psychopharmacology (2025)

Robyn P. ThomTracy L. WarrenSuha KhanRebecca A. MuhlePaul P. WangKristen BrennandNicole R. ZürcherJeremy Veenstra-VanderWeeleEllen J. Hoffman

autism spectrum disordermedicinepsychopharmacologytranslational precision medicineprecision medicinetranslational medicinerelated neurogenetic syndromes

Dynamic Convergence of Neurodevelopment Disorder Risk Genes: Seahorse Mito Stress and Mitochondrial Morphology Datasets. Zenodo (CERN European Organization for Nuclear Research) (2025)

Dynamic Convergence of Neurodevelopment Disorder Risk Genes: Zebrafish Baseline and Drug Behavioral Screen Dataset. Open MIND (2025)

From the Bench to Bedside: Understanding the Pathogenesis of Asd. Journal of the American Academy of Child & Adolescent Psychiatry (2025)

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