Faculty

Institution

Unit

Venue

Edward Wojcik

Louisiana State University Health Sciences Center, New Orleans

Affiliations

School of Medicine

Department Of Biochemistry And Molecular Biology

School of Graduate Studies

Department of Biochemistry & Molecular Biology

Louisiana State University Health Sciences Center, New Orleans

NoneEdward Wojcik is currently serving as a Biochemistry And Molecular Biology faculty at Louisiana State University Health Sciences Center, New Orleans.

Honors

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Experiences

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Education

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Edward Wojcik

Louisiana State University Health Sciences Center, New Orleans

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molecular biology protein science biochemistry cytoskeleton protein function molecular motors molecular cell biology biological chemistry enzyme inhibition genetics molecular and cellular biology kinesiology protein chemistry macromolecular machines biomolecular interactions protein transport therapeutic targets molecular genetics medicinal research mitophagy organelle dynamics enzyme catalysis structure-function enzyme kinetics protein genetics molecular regulation inter-organelle interactions translational research gene therapy genetic engineering complementary medicine pharmacotherapy oncogenes cellular therapy insect molecular biology developmental system insect biochemistry plo biology genome biology movement disorders musculoskeletal disorders systemic therapy novel therapies individual therapy clinical therapeutics therapeutic efficacy genomic mechanisms gene function genetic mechanisms developmental genetics gene structure genetic disorders mendelian disorder disease gene identification degenerative disease antiparasitic agent parasite genomics biochemical interaction cellular enzymology host specificity host factors molecular neurobiology cross-bridging mechanism clinical therapy telomere protection hoap-interacting protein allosteric drug discrimination mechanochemical changes kinesin switch small molecule screen difference ft-ir investigation allosteric interactions mitotic spindle zika protease cleavage atp hydrolysis scaffold protein putative ribosome-binding motif

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1858: Active and Allosteric Site Evolution Directs Ordered Water Use in Kinesin Catalysis. Journal of Biological Chemistry (2023)

biophysical chemistrywater usestructure-function enzyme kineticsenzymesbiocatalysiskinesin catalysisabstract 1858enzyme catalysischemistryorganic process researchbiomoleculesbiochemical sciencesbiochemistry

Polymorphic Interruption of Molecular Allosteric Pathways in Mitotic Kinesin-5: Comparison of Experiment and Algorithmic Prediction. Biophysical Journal (2022)

protein functionprotein structurepolymorphic interruptionbiological chemistrycomputational biologymolecular informaticsbiochemistrybiomolecular interactionsmolecular allosteric pathwayscytoskeletonmolecular cell biologybiomolecular structureprotein modelingprotein scienceprotein foldingmolecular motorsmolecular biophysicsmitotic kinesin-5systems biologyprotein bioinformaticsmolecular biologystructural molecular biologymulti-protein assembly

Inter-Organelle Interactions Between the Er and Mitotic Apparatus Facilitates Zika Protease Cleavage of Human Kinesin-5 and Contributes to Distinct Mitotic Defects. Biophysical Journal (2021)

distinct mitotic defectsprotein functioncytoskeletoncell signalingmolecular and cellular biologycell divisionmolecular cell biologymolecular biologymolecular neurodegenerationbiological chemistrymitophagyinter-organelle interactionsorganelle dynamicsprotein sciencehuman kinesin-5cellular biochemistrycell biology

Inter-Organelle Interactions Between the Er and Mitotic Spindle Facilitates Zika Protease Cleavage of Human Kinesin-5 and Results in Mitotic Defects. iScience (2021)

mitotic spindlemolecular motorsprotein functioncytoskeletonzika protease cleavagemolecular and cellular biologycell divisionmolecular cell biologymolecular biologybiological chemistrymitophagyinter-organelle interactionsorganelle dynamicsprotein sciencecellular biochemistrycell biology

Kinesin Atp Hydrolysis Requires Proton Tunneling Within the Zundel Cation and a Second Proton Transfer. Biophysical Journal (2021)

molecular motorsbiophysicsmolecular biophysicsbiophysical chemistrysecond proton transfercytoskeletonprotein scienceproton-coupled electron transferenzymesmolecular biologybiochemical sciencesbioenergeticsproton transferbiochemistryzundel cation

Allosteric Uncoupling of Microtubule Depolymerase Activity From Motility in Human Kinesin‐5. The FASEB Journal (2020)

Micquel DownsCatherine KimElizabeth KimLiqiong LiuSreeja ParameswaranSunyoung KimEdward Wojcik

biomechanicskinesiologyprotein functionallosteric uncouplinggeneticsmicrotubule depolymerase activityenzymesmembrane biologystructural biologyprotein scienceprotein engineeringneuroscience

Small Molecule Uncoupling of Microtubule Depolymerase Activity From Motility in Human Kinesin-5 During Mitotic Spindle Assembly. Biophysical Journal (2020)

molecular motorsbiophysicsbiological macromoleculesprotein assemblycytoskeletoncell motilitycell divisionmicrotubule depolymerase activitymolecular biologybiomoleculesmitotic spindle assemblyprotein sciencehuman kinesin-5cellular biochemistrymulti-protein assembly

Disruption of the Putative Ribosome-Binding Motif of a Scaffold Protein Impairs Cytochrome C Oxidase Subunit Expression in Leishmania Major. mSphere (2019)

Daviel CardenasCharity SylvesterBo CaoCatherine S. NationJuan C. PizarroHua LuJessie GuidryEdward J. WojcikBen L. Kelly

protein functioncell biologybiomolecular interactionshost factorsmolecular cell biologyenzymesstructural biologyprotein sciencemembrane biologyscaffold proteinmammalian biologygene expressionenzyme inhibitionputative ribosome-binding motifprotein geneticsgeneticshost specificityvirologymolecular biologystructural molecular biology

Differential Modulation of Microtubule Stability by Inhibitor‐Bound Kinesin‐5. The FASEB Journal (2018)

Catherine KimElizabeth KimLiqiong LiuEdward Wojcik

protein functionmuscle functionmolecular regulationdifferential modulationcytoskeletonprotein transportmolecular cell biologystructural biologyprotein sciencemembrane biologymicrotubule stabilityprotein chemistrycellular physiologymolecular physiologyprotein engineeringbiomechanicsbiophysicspharmacologyenzyme inhibitionneuroscience

Characterization of Kinesin Switch I Mutations That Cause Hereditary Spastic Paraplegia. PLoS ONE (2017)

muscular dystrophiescytoskeletonneurogeneticsgeneticskinesin switchdisease gene identificationmendelian disordermolecular geneticsmolecular biologymusculoskeletal disordersmovement disordersdegenerative diseasegenetic disorders

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Edward Wojcik

Louisiana State University Health Sciences Center, New Orleans

Affiliations

School of Medicine

Department Of Biochemistry And Molecular Biology

School of Graduate Studies

Department of Biochemistry & Molecular Biology

Louisiana State University Health Sciences Center, New Orleans

NoneEdward Wojcik is currently serving as a Biochemistry And Molecular Biology faculty at Louisiana State University Health Sciences Center, New Orleans.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Edward Wojcik

Louisiana State University Health Sciences Center, New Orleans

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1858: Active and Allosteric Site Evolution Directs Ordered Water Use in Kinesin Catalysis. Journal of Biological Chemistry (2023)

Polymorphic Interruption of Molecular Allosteric Pathways in Mitotic Kinesin-5: Comparison of Experiment and Algorithmic Prediction. Biophysical Journal (2022)

Inter-Organelle Interactions Between the Er and Mitotic Apparatus Facilitates Zika Protease Cleavage of Human Kinesin-5 and Contributes to Distinct Mitotic Defects. Biophysical Journal (2021)

Inter-Organelle Interactions Between the Er and Mitotic Spindle Facilitates Zika Protease Cleavage of Human Kinesin-5 and Results in Mitotic Defects. iScience (2021)

Kinesin Atp Hydrolysis Requires Proton Tunneling Within the Zundel Cation and a Second Proton Transfer. Biophysical Journal (2021)

Allosteric Uncoupling of Microtubule Depolymerase Activity From Motility in Human Kinesin‐5. The FASEB Journal (2020)

Micquel DownsCatherine KimElizabeth KimLiqiong LiuSreeja ParameswaranSunyoung KimEdward Wojcik

biomechanicskinesiologyprotein functionallosteric uncouplinggeneticsmicrotubule depolymerase activityenzymesmembrane biologystructural biologyprotein scienceprotein engineeringneuroscience

Small Molecule Uncoupling of Microtubule Depolymerase Activity From Motility in Human Kinesin-5 During Mitotic Spindle Assembly. Biophysical Journal (2020)

Disruption of the Putative Ribosome-Binding Motif of a Scaffold Protein Impairs Cytochrome C Oxidase Subunit Expression in Leishmania Major. mSphere (2019)

Daviel CardenasCharity SylvesterBo CaoCatherine S. NationJuan C. PizarroHua LuJessie GuidryEdward J. WojcikBen L. Kelly

Differential Modulation of Microtubule Stability by Inhibitor‐Bound Kinesin‐5. The FASEB Journal (2018)

Catherine KimElizabeth KimLiqiong LiuEdward Wojcik

Characterization of Kinesin Switch I Mutations That Cause Hereditary Spastic Paraplegia. PLoS ONE (2017)

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3
10 / page