Ecaterina Dumbrava

Ecaterina Dumbrava is a Senior Professor at The University of Texas MD Anderson Cancer Center. Her research focuses on early-phase oncology trials, cancer immunotherapy, and molecularly targeted therapeutics, with particular emphasis on TP53-mutant tumors, DNA damage response alterations, and engineered T-cell therapies. Her recent work includes leading phase 1 studies of p53 reactivators and MICA/B-targeted CAR T cells, alongside investigations into resistance mechanisms in advanced solid tumors. She has published extensively in venues including the New England Journal of Medicine and Journal of Clinical Oncology, contributing to precision oncology and the molecular profiling of pancreatic ductal adenocarcinoma.