Faculty

Institution

Unit

Venue

Doris E. Kretzschmar

Professor Associate Professor of Molecular and Medical Genetics Associate Professor of Neuroscience Associate Professor of Molecular and Cellular Biosciences

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Botanical Dietary Supplements Research Center (Benfra)

Center Of Layton Aging And Alzheimer'S Disease

OHSU-PSU School of Public Health

Oregon Health & Science University

Oregon National Primate Research Center

Science Education Opportunities

Doris E. Kretzschmar is currently serving as a Botanical Dietary Supplements Research Center (Benfra) Professor Associate Professor of Molecular and Medical Genetics Associate Professor of Neuroscience Associate Professor of Molecular and Cellular Biosciences at Oregon Health & Science University.

Honors

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Experiences

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Education

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Doris E. Kretzschmar

Oregon Health & Science University

Professor Associate Professor of Molecular and Medical Genetics Associate Professor of Neuroscience Associate Professor of Molecular and Cellular Biosciences

You can click a keyword to filter the displayed items

neuroscience molecular neurodegeneration insect molecular biology neurodegenerative diseases genetics molecular biology molecular neuroscience neurology neurogenetics molecular neurobiology developmental neurobiology ageing entomology neurons developmental system insect biochemistry alzheimer's disease avian biology mammalian biology degenerative disease drosophila melanogaster insect science biogerontology neuroscience of aging molecular psychiatry degenerative pathology chronobiology molecular cell biology genetic disorders cellular neurobiology developmental cell experimental gerontology cellular physiology neuroregeneration experimental neuropathology swiss cheese free radical biology developmental genetics aging process phytochemistry cellular senescence neurotransmitters neurochemistry progressive neurodegeneration centella asiatica aging cell neurodevelopmental disorders aging-associated diseases neurological disorders neuroprotection neurobiological mechanisms protein misfolding drug development neuroinflammation lifespan development nutrient physiology genetic mechanisms phytopharmacology clinical neuroscience disease gene identification psychiatric genetics placental development neuropeptides short-term variability age-dependent neurodegeneration alzheimer-amyloid plaque formation brain degeneration glial hyperwrapping cerebral palsy phosphatidylcholine homeostasis glial death embryonic lethality placental failure impaired vasculogenesis result drosophila amyloid-β peptide neurotoxic effects

Notable Scholarly Works

Notable Federal Grants

Collaborators

Scutellaria Lateriflora Extract Supplementation Provides Resilience to Age-Related Phenotypes in Drosophila Melanogaster. International Journal of Molecular Sciences (2026)

geneticsbiologyinsect biochemistrydrosophila melanogastercellular senescenceage-related phenotypesbiogerontologyinsect scienceentomologymolecular and cellular biologyinsect molecular biologyfitnesslifespan extension

Mouse Neuronal Dendritic Complexity and Resilience to Stress-Induced Depression in Drosophila Melanogaster Are Enhanced by Withania Somnifera Alkaloids. Journal of Ethnopharmacology (2025)

molecular psychiatryneuronsdopaminebehavioral neurosciencestress hormonesneurosciencemolecular neurodegenerationstress (biology)molecular neurosciencepharmacologybiological psychiatrywithania somnifera alkaloidsstress-induced depressiondrosophila melanogasterneuropsychopharmacologyinsect molecular biologyneurochemistryneurotransmittersneuropharmacology

The Cyclic Nucleotide Binding Sites of Swiss-Cheese, the Drosophila Orthologue of Human Pnpla6, Are Required for Its Catalytic Function. bioRxiv (Cold Spring Harbor Laboratory) (2025)

nucleic acid chemistrymolecular geneticsbiochemical sciencescyclic nucleotidebiochemistryhuman pnpla6gene structuremolecular and cellular biologygeneticsbiochemical geneticsinsect biochemistrycatalytic functionmolecular researchbiological chemistryenzymesinsect molecular biologybiosynthesisnucleic acidsmolecular biologymolecular basis

Centella Asiatica and Its Caffeoylquinic Acid and Triterpene Constituents Increase Dendritic Arborization of Mouse Primary Hippocampal Neurons and Improve Age-Related Locomotion Deficits in Drosophila. Frontiers in Aging (2024)

Karon RoweNora E. GrayJonathan A. ZweigAlexander LawNatascha TechenClaudia S. MaierAmala SoumyanathDoris Kretzschmar

developmental sciencegeriatricsaging processcentella asiaticadendritic arborizationageingneurosciencedevelopmental biologyneurologylifespan developmentcaffeoylquinic acidage-related locomotion deficitsmammalian biologyinsect molecular biologychronobiologyexperimental gerontologytriterpene constituentsneurochemistryneuroscience of agingneuroanatomydevelopmental neurobiologybiogerontologycognitive neuroscience

The Amyloid Precursor Protein Intracellular Domain Induces Sleep Disruptions and Its Nuclear Localization Fluctuates in Circadian Pacemaker Neurons in Drosophila and Mice. Neurobiology of Disease (2024)

Dani M. LongOlga CravetchiEileen S. ChowCharles AllenDoris Kretzschmar

clinical neuroscienceneurologyanimal physiologycircadian pacemaker neuronsnuclear localization fluctuatesneurosciencemolecular neurobiologymolecular neuroscienceneurophysiologymammalian biologyneurodegenerative diseasesphysiology

Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in Centella Asiatica Extracts That Mediate Resilience to Chronic Stress in Drosophila Melanogaster. Nutrients (2023)

Helen HolvoetDani M. LongLiping YangJaewoo ChoiLuke MarneyBurkhard PoeckClaudia S. MaierAmala SoumyanathDoris KretzschmarRoland Strauss

resiliencephytopharmacologymembrane biologyavian biologymicrobiologynutrient physiologybotanyanimal nutritionpharmacologymedicinal chemistrynutritional sciencesdrosophila melanogastermain compoundsclinical nutritionphytochemistryplant physiologynutritional biochemistrychlorogenic acidsecologyentomology

Age-Dependent Effects of Blue Light Exposure on Lifespan, Neurodegeneration, and Mitochondria Physiology in Drosophila Melanogaster. npj Aging (2022)

Yujuan SongJun YangAlexander D. LawDavid A. HendrixDoris KretzschmarMatthew RobinsonJadwiga M. Giebultowicz

biologygeriatricsageingdrosophila melanogasterblue light exposuremitochondria physiologymammalian biologyage-dependent effects

Chronic Blue Light Leads to Accelerated Aging in Drosophila by Impairing Energy Metabolism and Neurotransmitter Levels. Frontiers in Aging (2022)

Jun YangYujuan SongAlexander D. LawConner J. RoganKelsey ShimodaDanijel DjukovicJeffrey C. AndersonDoris KretzschmarDavid A. HendrixJadwiga M. Giebultowicz

experimental gerontologyneurologybiologytransgenerational effectavian biologylifespan developmentageinggeriatricscognitive impairmentmammalian biologyneuroscienceaging processneuroscience of agingneurotransmitter levelsbiogerontologycognitive neuroscienceinsect molecular biology

Developing a Rational, Optimized Product of Centella Asiatica for Examination in Clinical Trials: Real World Challenges. Frontiers in Nutrition (2022)

Kirsten M. WrightJanis McFerrinArmando Alcázar MagañaJoanne RobertsMaya CarusoDoris KretzschmarJan F. StevensClaudia S. MaierJoseph F. QuinnAmala Soumyanath

performance evaluationhealth sciencescentella asiaticareal world challengesoptimized productdrug development

Ftd-Associated Mutations in Tau Result in a Combination of Dominant and Recessive Phenotypes. Neurobiology of Disease (2022)

Alexander D. LawMarlène CassarDani M. LongEileen S. ChowJadwiga M. GiebultowiczAnjana VenkataramananRoland StraussDoris Kretzschmar

geneticsneurologyhuman geneticsneurosciencemolecular neurobiologyftd-associated mutations

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Doris E. Kretzschmar

Professor Associate Professor of Molecular and Medical Genetics Associate Professor of Neuroscience Associate Professor of Molecular and Cellular Biosciences

Oregon Health & Science University

Affiliations

OHSU School of Medicine

Botanical Dietary Supplements Research Center (Benfra)

Center Of Layton Aging And Alzheimer'S Disease

OHSU-PSU School of Public Health

Oregon Health & Science University

Oregon National Primate Research Center

Science Education Opportunities

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Doris E. Kretzschmar

Oregon Health & Science University

Professor Associate Professor of Molecular and Medical Genetics Associate Professor of Neuroscience Associate Professor of Molecular and Cellular Biosciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Scutellaria Lateriflora Extract Supplementation Provides Resilience to Age-Related Phenotypes in Drosophila Melanogaster. International Journal of Molecular Sciences (2026)

Mouse Neuronal Dendritic Complexity and Resilience to Stress-Induced Depression in Drosophila Melanogaster Are Enhanced by Withania Somnifera Alkaloids. Journal of Ethnopharmacology (2025)

The Cyclic Nucleotide Binding Sites of Swiss-Cheese, the Drosophila Orthologue of Human Pnpla6, Are Required for Its Catalytic Function. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Karon RoweNora E. GrayJonathan A. ZweigAlexander LawNatascha TechenClaudia S. MaierAmala SoumyanathDoris Kretzschmar

Dani M. LongOlga CravetchiEileen S. ChowCharles AllenDoris Kretzschmar

Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in Centella Asiatica Extracts That Mediate Resilience to Chronic Stress in Drosophila Melanogaster. Nutrients (2023)

Helen HolvoetDani M. LongLiping YangJaewoo ChoiLuke MarneyBurkhard PoeckClaudia S. MaierAmala SoumyanathDoris KretzschmarRoland Strauss

Age-Dependent Effects of Blue Light Exposure on Lifespan, Neurodegeneration, and Mitochondria Physiology in Drosophila Melanogaster. npj Aging (2022)

Yujuan SongJun YangAlexander D. LawDavid A. HendrixDoris KretzschmarMatthew RobinsonJadwiga M. Giebultowicz

biologygeriatricsageingdrosophila melanogasterblue light exposuremitochondria physiologymammalian biologyage-dependent effects

Chronic Blue Light Leads to Accelerated Aging in Drosophila by Impairing Energy Metabolism and Neurotransmitter Levels. Frontiers in Aging (2022)

Jun YangYujuan SongAlexander D. LawConner J. RoganKelsey ShimodaDanijel DjukovicJeffrey C. AndersonDoris KretzschmarDavid A. HendrixJadwiga M. Giebultowicz

Developing a Rational, Optimized Product of Centella Asiatica for Examination in Clinical Trials: Real World Challenges. Frontiers in Nutrition (2022)

Kirsten M. WrightJanis McFerrinArmando Alcázar MagañaJoanne RobertsMaya CarusoDoris KretzschmarJan F. StevensClaudia S. MaierJoseph F. QuinnAmala Soumyanath

performance evaluationhealth sciencescentella asiaticareal world challengesoptimized productdrug development

Ftd-Associated Mutations in Tau Result in a Combination of Dominant and Recessive Phenotypes. Neurobiology of Disease (2022)

Alexander D. LawMarlène CassarDani M. LongEileen S. ChowJadwiga M. GiebultowiczAnjana VenkataramananRoland StraussDoris Kretzschmar

geneticsneurologyhuman geneticsneurosciencemolecular neurobiologyftd-associated mutations

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10 / page