Dong-Ming Su

Professor Microbiology Immunology & Genetics

University of North Texas Health Science Center

Affiliations

Graduate School of Biomedical Sciences ; Microbiology, Immunology & Genetics

School of Biomedical Sciences

Microbiology, Immunology and Genetics

Dong-ming Su is currently serving as a Graduate School Of Biomedical Sciences ; Microbiology, Immunology & Genetics Professor Microbiology Immunology & Genetics at University of North Texas Health Science Center.

Honors

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Experiences

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Education

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Dong-Ming Su

University of North Texas Health Science Center

Professor Microbiology Immunology & Genetics

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immunology immune responses cell biology aging cell ageing neurology neuroimmunology inflammation cellular physiology cell transplantation lymphocyte development cellular senescence neuroscience stem cells autoimmunity experimental gerontology cell research stroke neurodegenerative diseases cellular therapy neuroscience of aging molecular neurodegeneration stem cell research reproductive immunology neuroinflammation brain-immune interaction aging process t-regulatory cell adaptive immune system cellular immune responses immunogenetics clinical immunology atrophied thymus bone marrow transplantation thyroid in vitro toxicology molecular cell biology cancer cells mammalian biology chronic inflammation immune dysregulation cerebrovascular disease ischemic syndrome stem cell transplantation immunochemistry immunotoxicology small rna melanoma disease progression cell specialization stem-cell therapy neural stem cells knockout mice biological significance developmental immunology immunological memory immunological biomarkers signaling pathways biogerontology cell regulation antigen processing focal ischemia secondary injury dose regimens ischemic stroke neuroinflammatory response immune system ttreg generation age-related disruption negative selection induced decline progenitor niches bone marrow dichotomous impact t cells thymic involution stromal cells apoptosis immunotherapy cell differentiation angiostrongylus cantonensis gene targeting transcription factors hematopoietic stem cells thymus gland epithelial cells central tolerance

Notable Scholarly Works

Notable Federal Grants

Collaborators

Atrophied Thymus, a Tumor Reservoir for Harboring Melanoma Cells. Molecular Cancer Research (2018)

melanomaatrophied thymuscell researchcancer cellstumor microenvironmenttumor biologycell biology

Extracellular Vesicles Extracted From Young Donor Serum Attenuate Inflammaging via Partially Rejuvenating Aged T-Cell Immunotolerance. FASEB Journal (2018)

immunologyimmunological biomarkersautoimmune diseasescellular physiologyclinical immunologyinflammationaging cellextracellular vesiclescell researchimmunological memoryt-cell immunotoleranceimmune responsescell transplantationautoimmunitycell biology

A Fine-Tune Role of Mir-125A-5P on Foxn1 During Age-Associated Changes in the Thymus. Aging and Disease (2017)

small rnagene expressionage-associated changescellular physiologyaging celltranscription (biology)geneticstranscription factorsmolecular cell biologyimmunogeneticsepigeneticsfine-tune rolecell biology

Capacity of Ttreg Generation is Not Impaired in the Atrophied Thymus. PLoS Biology (2017)

physiologymuscular dystrophiesatrophied thymusthyroidgeneticsttreg generation

Immune Senescence: Significance of the Stromal Microenvironment. Clinical and Experimental Immunology (2017)

immunologycellular senescenceimmune senescencereproductive immunologyageingcell deathaging cellimmune responsescell biology

Impact of Aging Immune System on Neurodegeneration and Potential Immunotherapies. Progress in Neurobiology (2017)

immunologyneurologyneuroinflammationageingaging cellneuroimmunologymolecular neurodegenerationimmune responsesbrain-immune interactionaging processimmune systemneuroscience of agingneurodegenerative diseases

Micrornas Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors. Journal of Immunology Research (2017)

Minwen XuXiaoli ZhangRuiyun HongDong-Ming SuLiefeng Wang

immunologydisease progressionthymic epitheliumgene expressionage-related thymic involutiontranscription factorsmolecular biology

Soluble Antigens From the Neurotropic Pathogen Angiostrongylus Cantonensis Directly Induce Thymus Atrophy in a Mouse Model. Oncotarget (2017)

immunologymouse modelpathogenesissoluble antigensautoimmune diseasesclinical immunologythymus atrophyparasitologyantigen processingimmune responsesinfectious diseasesimmunopathologyimmunity (medicine)laboratory immunology

Friend or Foe: The Dichotomous Impact of T Cells on Neuro-De/Re-Generation During Aging. Oncotarget (2016)

cellular senescenceageingexperimental gerontologyaging cellneuroimmunologycell researchdichotomous impactmolecular neurodegenerationneuroscience of agingt cellsaging processneuroscienceneurodegenerative diseasescell biology

Cross-Talk Between Human Neural Stem/Progenitor Cells and Peripheral Blood Mononuclear Cells in an Allogeneic Co-Culture Model. PLoS ONE (2015)

stem cell researchcellular physiologyallogeneic co-culture modelhaematopoiesisregenerative medicineneural stem cellsstem-cell therapystem cellscell transplantationcell specializationcellular therapyneurosciencecell biology