Faculty

Institution

Unit

Venue

Donald Becker

Department Head

University of Nebraska–Lincoln

Affiliations

Agricultural Sciences and Natural Resources

Undergraduate Programs

Arts and Sciences

Sciences

Undergraduate Programs

Biochemistry

Microbiology

Sciences

Biochemistry

Microbiology

Donald Becker is currently serving as an Agricultural Sciences And Natural Resources Department Head at University of Nebraska–Lincoln.

Honors

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Experiences

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Education

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Donald Becker

University of Nebraska–Lincoln

Department Head

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biochemistry molecular biology enzymes structural biology protein science redox biology protein structure structural molecular biology biophysics membrane biology genetics biological chemistry protein chemistry enzyme catalysis biomolecular structure biochemical sciences proline utilization oxidative stress structure-function enzyme kinetics signal transduction enzyme inhibition proline dehydrogenase gene expression chemical biology structural chemistry plant biochemistry proline dehydrogenase domain biological inorganic chemistry redox signaling molecular regulation proline metabolism plant physiology plant science free radical biology biocatalysis microbial physiology escherichia coli molecular science molecular metabolism molecular physiology bacteriology plant biotechnology genome biology plant biology plant metabolism enzyme specificity protein genetics protein function molecular substrates plant molecular biology aldehyde dehydrogenase protein x-ray crystallography transcription regulation redox chemistry multifunctional puta flavoprotein bifunctional proline utilization substrate channeling dna-binding domain trifunctional proline utilization protein biosynthesis cellular enzymology gene function molecular microbiology protein expression gene regulation rna biology microbial proteomics bio-orthogonal chemistry experimental biophysics medical biophysics monofunctional proline dehydrogenase redox properties puta protein structural basis conformational changes multifunctional proline utilization metabolism redox regulation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Elucidation of Mechanisms Associated With Proline Metabolism and Redox Balance in Peanut Microsymbionts Exposed to Water Stress. (2024)

Ana Laura FurlanJuan Francisco VillaEliana BianucciDonald Becker

water stressproline metabolismpeanut microsymbiontsbiochemistrymetabolismredox balance

Noncovalent Inhibition and Covalent Inactivation of Proline Dehydrogenase by Analogs of N -Propargylglycine. Biochemistry (2024)

John J. TannerJuan JiAlexandra N. BognerGary K. ScottSagar M. PatelJavier SeravalliKent S. GatesChristopher C. BenzDonald F. Becker

enzyme inhibitionpeptide sciencenoncovalent inhibitioncovalent inactivationbiomolecular engineeringenzymesmolecular biologyenzyme catalysisenzymatic modificationproline dehydrogenasebiochemistry

Functional Impact of a Cancer-Related Variant in Human Δ 1 -Pyrroline-5-Carboxylate Reductase 1. ACS Omega (2023)

Oseeyi I. DauduKaylen R. MeeksLu ZhangJavier SeravalliJohn J. TannerDonald F. Becker

pharmacologycancer geneticscancer researchgeneticsmolecular biologyoncologycancer-related variantcancer biologyfunctional modificationfunctional impact

Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Carcinogenesis by Modulating Microtubule-Associated Serine/Threonine Kinase-Like/Wnt/β-Catenin Signaling. Cells (2023)

Raju Lama TamangBalawant KumarSagar M. PatelIshwor ThapaAlshomrani AhmadVikas KumarRizwan AhmadDonald F. BeckerDundy (Kiran) BastolaPunita DhawanAmar B. Singh

signaling pathwayscell regulationcancer biologyredox signalingcancer researchcell signalingredox biologyoncologymolecular biologycolorectal cancersignal transductiontumor biologybiochemistrycell biology

Molecular Determinants of Mitochondrial Shape and Function and Their Role in Glaucoma. Antioxidants and Redox Signaling (2022)

Oleh KhalimonchukDonald F. Becker

molecular neurobiologyantioxidantsmolecular cell biologymembrane biologydermatologyredox signalingmitochondrial shaperedox chemistrymolecular determinantsmolecular physiologytumor biologyglaucomafree radical biologyredox biologygeneticsmitochondrial functionmolecular biologysignal transductionoxidative stress

Disease Variants of Human Δ1-Pyrroline-5-Carboxylate Reductase 2 (Pycr2). Archives of Biochemistry and Biophysics (2021)

Sagar M. PatelJavier SeravalliXinwen LiangJohn J. TannerDonald F. Becker

biophysicscancer geneticsgeneticsbiochemistryprotein sciencehuman geneticsdisease variantsmolecular medicine

Evidence for Proline Catabolic Enzymes in the Metabolism of Thiazolidine Carboxylates. Biochemistry (2021)

Yizi MaoJavier SeravalliThomas G. SmithMartha MortonJohn J. TannerDonald F. Becker

metabolismthiazolidine carboxylatesbiochemistryproline catabolic enzymes

Kinetic Characterization of Proline Utilization a (Puta) Using Proline Analogues. The FASEB Journal (2021)

YiZi MaoJavier SeravalliJohn TannerDonald Becker

proline utilizationpharmacologybiomolecular engineeringenzymesproline analogueskinetic characterization

Kinetics of Human Pyrroline-5-Carboxylate Reductase in L-Thioproline Metabolism. Amino Acids (2021)

Sagar M. PatelJavier SeravalliKyle M. StiersJohn J. TannerDonald F. Becker

physiologychemical kineticspharmacologyendocrinologyenzymeshepatologymetabolismprotein sciencebiochemistryl-thioproline metabolism

Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. ACS Chemical Biology (2021)

Ashley C. CampbellAustin R. PraterAlexandra N. BognerThomas P. QuinnKent S. GatesDonald F. BeckerJohn J. Tanner

enzyme inhibitioncovalent irreversible inactivationredox biologyphotochemistrychemical biologyenzymesmolecular biologyenzyme catalysisproline dehydrogenasesignal transductionprotein sciencebiochemistry

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Donald Becker

Department Head

University of Nebraska–Lincoln

Affiliations

Agricultural Sciences and Natural Resources

Undergraduate Programs

Arts and Sciences

Sciences

Undergraduate Programs

Biochemistry

Microbiology

Sciences

Biochemistry

Microbiology

Donald Becker is currently serving as an Agricultural Sciences And Natural Resources Department Head at University of Nebraska–Lincoln.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Donald Becker

University of Nebraska–Lincoln

Department Head

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Elucidation of Mechanisms Associated With Proline Metabolism and Redox Balance in Peanut Microsymbionts Exposed to Water Stress. (2024)

Ana Laura FurlanJuan Francisco VillaEliana BianucciDonald Becker

water stressproline metabolismpeanut microsymbiontsbiochemistrymetabolismredox balance

Noncovalent Inhibition and Covalent Inactivation of Proline Dehydrogenase by Analogs of N -Propargylglycine. Biochemistry (2024)

John J. TannerJuan JiAlexandra N. BognerGary K. ScottSagar M. PatelJavier SeravalliKent S. GatesChristopher C. BenzDonald F. Becker

enzyme inhibitionpeptide sciencenoncovalent inhibitioncovalent inactivationbiomolecular engineeringenzymesmolecular biologyenzyme catalysisenzymatic modificationproline dehydrogenasebiochemistry

Functional Impact of a Cancer-Related Variant in Human Δ 1 -Pyrroline-5-Carboxylate Reductase 1. ACS Omega (2023)

Oseeyi I. DauduKaylen R. MeeksLu ZhangJavier SeravalliJohn J. TannerDonald F. Becker

pharmacologycancer geneticscancer researchgeneticsmolecular biologyoncologycancer-related variantcancer biologyfunctional modificationfunctional impact

Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Carcinogenesis by Modulating Microtubule-Associated Serine/Threonine Kinase-Like/Wnt/β-Catenin Signaling. Cells (2023)

Raju Lama TamangBalawant KumarSagar M. PatelIshwor ThapaAlshomrani AhmadVikas KumarRizwan AhmadDonald F. BeckerDundy (Kiran) BastolaPunita DhawanAmar B. Singh

Molecular Determinants of Mitochondrial Shape and Function and Their Role in Glaucoma. Antioxidants and Redox Signaling (2022)

Oleh KhalimonchukDonald F. Becker

Disease Variants of Human Δ1-Pyrroline-5-Carboxylate Reductase 2 (Pycr2). Archives of Biochemistry and Biophysics (2021)

Sagar M. PatelJavier SeravalliXinwen LiangJohn J. TannerDonald F. Becker

biophysicscancer geneticsgeneticsbiochemistryprotein sciencehuman geneticsdisease variantsmolecular medicine

Evidence for Proline Catabolic Enzymes in the Metabolism of Thiazolidine Carboxylates. Biochemistry (2021)

Yizi MaoJavier SeravalliThomas G. SmithMartha MortonJohn J. TannerDonald F. Becker

metabolismthiazolidine carboxylatesbiochemistryproline catabolic enzymes

Kinetic Characterization of Proline Utilization a (Puta) Using Proline Analogues. The FASEB Journal (2021)

YiZi MaoJavier SeravalliJohn TannerDonald Becker

proline utilizationpharmacologybiomolecular engineeringenzymesproline analogueskinetic characterization

Kinetics of Human Pyrroline-5-Carboxylate Reductase in L-Thioproline Metabolism. Amino Acids (2021)

Sagar M. PatelJavier SeravalliKyle M. StiersJohn J. TannerDonald F. Becker

physiologychemical kineticspharmacologyendocrinologyenzymeshepatologymetabolismprotein sciencebiochemistryl-thioproline metabolism

Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. ACS Chemical Biology (2021)

Ashley C. CampbellAustin R. PraterAlexandra N. BognerThomas P. QuinnKent S. GatesDonald F. BeckerJohn J. Tanner

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5
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Similar Faculty Members

Ivan Rayment

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University of Wisconsin–Madison

protein bioinformatics

biomolecular structure

John Tanner

Institution

University of Missouri

quantum biology

biological chemistry

Evan R. Kantrowitz

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enzymes

biochemistry

Joseph Jez

Institution

Washington University in St. Louis

plant hormone

plant hormone responses

Kelley Moremen

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glycan trimming enzymes

glycosylation

Rowena Matthews

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University of Michigan

molecular metabolism

metabolism

John M. Denu

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molecular metabolism

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Mary F. Roberts

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biochemistry

enzymes

Catherine Drennan

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Elizabeth Komives

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protein modeling

biomolecular structure