Dino Samartzis

Dino Samartzis is a High Senior Professor at Rush University specializing in orthopaedic and spine surgery, spinal cord medicine, and musculoskeletal disorders. His research focuses on lumbar spine pathology, intervertebral disc degeneration, and the clinical translation of precision medicine for low back pain. He has led landmark studies, including a Nature-published translational genomics analysis of osteoarthritis across 1,962,069 individuals and investigations into the β-catenin/CCL2 pathway in disc degeneration. His recent work also addresses predictive biomarkers, pain phenotyping, and the impact of artificial intelligence on scientific integrity. He actively contributes to international consensus efforts, including the ISSLS phenotype/precision spine focus group.