Faculty

Institution

Unit

Venue

David Mueller

Rosalind Franklin University of Medicine and Science

Affiliations

School Of Chicago Medical

Center For Genetic Diseases

Department Of Clinical Sciences

Department Of Foundational Sciences And Humanities

Chicago Medical School

Foundational Sciences and Humanities

Midwest Proteome Center

School Of Chicago Medical

Foundational Sciences and Humanities

Department of Humanities & Health Care

Illinois Board of Higher Education

Rosalind Franklin University of Medicine and Science

NoneDavid Mueller is currently serving as a Center For Genetic Diseases faculty at Rosalind Franklin University of Medicine And Science.

Honors

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Experiences

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Education

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David Mueller

Rosalind Franklin University of Medicine and Science

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molecular biology biochemistry enzymes yeast molecular and cellular biology protein science structural biology protein structure structural molecular biology cellular enzymology biological chemistry genetics molecular genetics molecular cell biology mitochondrial function cell and molecular biology molecular metabolism bioenergetics fungal genetics mutagenesis (molecular biology technique) biomolecular structure structure-function enzyme kinetics biochemical sciences cell metabolism enzyme inhibition cell biology membrane biology molecular research nucleic acids protein biosynthesis cellular biochemistry mitochondrial biogenesis protein phosphorylation molecular regulation yeast atp synthase atp synthase redox biology enzyme catalysis fungal cell biology yeast mitochondrial atpase peptides microbial cell factory mitochondrial dynamics mutagenesis cancer genetics x-ray crystallography rna biology cell regulation mitochondrial atp synthase mitochondrial atpase yeast saccharomyces cerevisiae exome sequencing vaccine targets vaccine development vaccine efficacy vaccine design proteinlipid interaction genome sequencing dna sequencing biocatalysis structural composition conformational studies microbial genetics microbial physiology cellular biology cancer risk tumor targeting mitochondrial cristae morphology candidate multi-epitope vaccine high-resolution cryo-em analysis lipid membrane rotary catalytic mechanism novel features open conformation understanding structure steady state analysis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tor-Dependent Regulation of the Yeast Homolog of the Juvenile Batten Disease-Associated Gene Cln3. Microbial Cell (2026)

geneticsmolecular cell biologygene functiongene expressionmolecular geneticstor-dependent regulationgene regulationyeast homologmolecular biologygenome biologymolecular and cellular biologyyeast

Abstract 1760 Regulation and Functional Insights Into the Yeast Homolog of the Juvenile Batten Disease Protein. Journal of Biological Chemistry (2025)

geneticsmolecular cell biologygene expressionyeast homologfunctional insightsabstract 1760molecular biologymolecular and cellular biologyyeastfungal geneticscell and molecular biologymolecular regulation

Abstract 2109 Identification of Genomic Elements Regulating the Expression of Yhc3; the Yeast Homolog of the Batten Disease Causing Gene, Cln3. Journal of Biological Chemistry (2025)

geneticsbatten diseasemolecular cell biologygene functiongene expressionmolecular geneticsgenomicsabstract 2109genomic mechanismsmolecular biologygenome biologygenomic elementsgenome structureyeastgene characterization

Conformational Ensemble of Yeast Atp Synthase at Low Ph Reveals Unique Intermediates and Plasticity in F1–Fo Coupling. Nature Structural & Molecular Biology (2024)

cellular enzymologybiomolecular structurebiophysicsstructural biologyconformational ensembleenzyme catalysisprotein structurestructure-function enzyme kineticsbiochemistrymolecular biologystructural molecular biologybioenergeticsyeast atp synthasef1–fo couplingyeastenzymesprotein science

Tnk2/Ack1-Mediated Phosphorylation of Atp5F1A (Atp Synthase F1 Subunit Alpha) Selectively Augments Survival of Prostate Cancer While Engendering Mitochondrial Vulnerability. Autophagy (2022)

Surbhi ChouhanMithila SawantCody WeimholtJingqin LuoRobert W. SprungMailyn TerradoDavid M. MuellerH. Shelton EarpNupam P. Mahajan

tumor targetingmedicinecell regulationmembrane biologycancer researchtumor biologypharmacologyautophagyoncologybrain tumor researchcancer geneticsprotein phosphorylationcancer riskprostate cancerurologyoncogenesenzyme inhibitionmedicinal researchmitochondrial vulnerability

Early Onset Severe Atp1A2 Epileptic Encephalopathy: Clinical Characteristics and Underlying Mutations. Epilepsy & Behavior (2021)

Mary E. Moya-MendezDavid M. MuellerMilton PrattMelanie BonnerCourtney ElliottArsen HunanyanGary KuceraCheryl BockLyndsey PrangeJoan JasienKaren KeoughVandana ShashiMarie McDonaldMohamad A. Mikati

neurologyepileptic encephalopathyunderlying mutationsclinical characteristicsepilepsy

The Pathogenic M.8993 T Gt; G Mutation in Mitochondrial Atp6 Gene Prevents Proton Release From the Subunit C -Ring Rotor of Atp Synthase. Human Molecular Genetics (2021)

molecular geneticsdna repairbiochemistrybioenergeticsmolecular and cellular biologymutagenesis (molecular biology technique)geneticsg mutationcell metabolismmolecular researchmitochondrial biogenesismolecular cell biologyenzymescell and molecular biologymitochondrial dynamicsmitochondrial functionmolecular metabolismmolecular biologyatp synthasecellular enzymologypathogenic m.8993 t

A Candidate Multi-Epitope Vaccine Against Sars-Cov-2. Scientific Reports (2020)

Tamalika KarUtkarsh NarsariaSrijita BasakDebashrito DebFilippo CastiglioneDavid M. MuellerAnurag P. Srivastava

vaccine developmentvaccinessars-cov-2infectious diseasesvaccine targetscovid-19virus researchpeptidesvaccine efficacyimmunologyantiviral researchvaccinationvaccine designcandidate multi-epitope vaccine

Bedaquiline Inhibits the Yeast and Human Mitochondrial Atp Synthases. Communications Biology (2020)

mitochondrial functioncell metabolismenzyme inhibitionbiochemistrymolecular metabolismenzymesmetabolic pathways

D-DemØ, a Distinct Phenotype Caused by Atp1A3 Mutations. Neurology Genetics (2020)

Lyndsey PrangeMilton PrattKristin HermanRaphael SchiffmannDavid M. MuellerMelissa McLeanMary Moya MendezNicole WalleyErin L. HeinzenDavid GoldsteinVandana ShashiArsen HunanyanVijay PagadalaMohamad A. Mikati

geneticsneurologyhuman geneticsneurogeneticsgenetic disorderscancer geneticsdistinct phenotype

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David Mueller

Rosalind Franklin University of Medicine and Science

Affiliations

School Of Chicago Medical

Center For Genetic Diseases

Department Of Clinical Sciences

Department Of Foundational Sciences And Humanities

Chicago Medical School

Foundational Sciences and Humanities

Midwest Proteome Center

School Of Chicago Medical

Foundational Sciences and Humanities

Department of Humanities & Health Care

Illinois Board of Higher Education

Rosalind Franklin University of Medicine and Science

NoneDavid Mueller is currently serving as a Center For Genetic Diseases faculty at Rosalind Franklin University of Medicine And Science.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

David Mueller

Rosalind Franklin University of Medicine and Science

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Tor-Dependent Regulation of the Yeast Homolog of the Juvenile Batten Disease-Associated Gene Cln3. Microbial Cell (2026)

geneticsmolecular cell biologygene functiongene expressionmolecular geneticstor-dependent regulationgene regulationyeast homologmolecular biologygenome biologymolecular and cellular biologyyeast

Abstract 1760 Regulation and Functional Insights Into the Yeast Homolog of the Juvenile Batten Disease Protein. Journal of Biological Chemistry (2025)

Abstract 2109 Identification of Genomic Elements Regulating the Expression of Yhc3; the Yeast Homolog of the Batten Disease Causing Gene, Cln3. Journal of Biological Chemistry (2025)

Conformational Ensemble of Yeast Atp Synthase at Low Ph Reveals Unique Intermediates and Plasticity in F1–Fo Coupling. Nature Structural & Molecular Biology (2024)

Tnk2/Ack1-Mediated Phosphorylation of Atp5F1A (Atp Synthase F1 Subunit Alpha) Selectively Augments Survival of Prostate Cancer While Engendering Mitochondrial Vulnerability. Autophagy (2022)

Surbhi ChouhanMithila SawantCody WeimholtJingqin LuoRobert W. SprungMailyn TerradoDavid M. MuellerH. Shelton EarpNupam P. Mahajan

Early Onset Severe Atp1A2 Epileptic Encephalopathy: Clinical Characteristics and Underlying Mutations. Epilepsy & Behavior (2021)

Mary E. Moya-MendezDavid M. MuellerMilton PrattMelanie BonnerCourtney ElliottArsen HunanyanGary KuceraCheryl BockLyndsey PrangeJoan JasienKaren KeoughVandana ShashiMarie McDonaldMohamad A. Mikati

neurologyepileptic encephalopathyunderlying mutationsclinical characteristicsepilepsy

The Pathogenic M.8993 T Gt; G Mutation in Mitochondrial Atp6 Gene Prevents Proton Release From the Subunit C -Ring Rotor of Atp Synthase. Human Molecular Genetics (2021)

A Candidate Multi-Epitope Vaccine Against Sars-Cov-2. Scientific Reports (2020)

Tamalika KarUtkarsh NarsariaSrijita BasakDebashrito DebFilippo CastiglioneDavid M. MuellerAnurag P. Srivastava

Bedaquiline Inhibits the Yeast and Human Mitochondrial Atp Synthases. Communications Biology (2020)

mitochondrial functioncell metabolismenzyme inhibitionbiochemistrymolecular metabolismenzymesmetabolic pathways

D-DemØ, a Distinct Phenotype Caused by Atp1A3 Mutations. Neurology Genetics (2020)

geneticsneurologyhuman geneticsneurogeneticsgenetic disorderscancer geneticsdistinct phenotype

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7
10 / page