Faculty

Institution

Unit

Venue

David M Spencer

Visiting Professor

Baylor College of Medicine

Affiliations

Baylor College of Medicine Research

David M Spencer is currently serving as a Baylor College Of Medicine Research Visiting Professor at Baylor College of Medicine.

Honors

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Experiences

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Education

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David M Spencer

Baylor College of Medicine

Visiting Professor

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immunology prostate cancer immune responses cell biology medicinal research molecular biology oncology tumor biology cellular therapy cancer research cancer cells genetics cellular immune responses cell signaling oncogenes cancer biology cancer treatment gene expression t-regulatory cell signal transduction immune checkpoint inhibitors cancer discovery prostatic disease cell death cancer immunosurveillance adaptive immune system cell transplantation apoptosis clinical immunology novel therapies stem cell research tumor targeting vaccine research pharmacotherapy cancer imaging cancer genetics experimental medicine clinical transplantation cell proliferation stem cell transplantation tumor suppressors molecular immunology protein science molecular cell biology transcription regulation cell control cell therapy fibroblast growth factors therapeutic efficacy mammalian biology biological chemistry stem-cell therapy cancer growth genitourinary cancers immunological memory signaling pathways safety switch dendritic cell function human dendritic cells prostate cancer progression suicide protein expression angiogenesis experimental biology artificial death switches conditional activation death switch human glandular kallikrein ezc-prostate model chimeric antigen receptor rimiducid-dependent activation adoptive cell therapy inducible apoptosis synthetic ligands t-cell therapy initiator caspase cancer letter urology radiation oncology benign prostatic hyperplasia gene therapy

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Enhanced Activation of Human Dendritic Cells by Inducible Cd40 and Toll-Like Receptor-4 Ligation. (2023)

Natalia LaptevaMamatha R. SeethammagariBrent A. HanksJianghong JiangJonathan M. LevittKevin M. SlawinDavid M. Spencer

cell signalingimmunologycell biologyimmune responseshuman dendritic cellsadaptive immune systemdata sciencecatalyst activationreceptorsinnate immune systemenhanced activation

Data From Versatile Prostate Cancer Treatment With Inducible Caspase and Interleukin-12. (2023)

Ekaterina Yu. NikitinaSmruti A. DesaiXiuqin ZhaoWeitao SongAnnie Z. LuoRama D. GangulaKevin M. SlawinDavid M. Spencer

inducible caspaseurologycancer treatmentprostate cancer

Supplementary Figures 1-3 From Ezc-Prostate Models Offer High Sensitivity and Specificity for Noninvasive Imaging of Prostate Cancer Progression and Androgen Receptor Action. (2023)

Mamatha R. SeethammagariXiaoming XieNorman M. GreenbergDavid M. Spencer

prostate cancer progressionezc-prostate modelsnoninvasive imagingprostate cancerandrogen receptor actionurologyhigh sensitivity

Abstract 2193: Small Molecule Inducible Myd88/Cd40 (Imc) in Car-T Cells Can Repolarize M2 Macrophage to an Anti-Tumor M1 Phenotype. Cancer Research (2020)

Xiaohong WangKonrad GabrusiewiczDavid M. SpencerAaron E. FosterJ. Henri Bayle

oncogenesmolecular immunologytumor targetingtumor biologycancer immunotherapyimmunologycell biologymedicinal researchcar-t cellscellular therapycancer researchcellular immune responsesmolecular biologytherapeutic targetsimmune checkpoint inhibitorstumor microenvironmentcancer biology

Engineering Tolerance Toward Allogeneic Car-T Cells by Regulation of Mhc Surface Expression With Human Herpes Virus-8 Proteins. Molecular Therapy (2020)

Xiaomei WangFabricio G. CabreraKelly L. SharpDavid M. SpencerAaron E. FosterJ. Henri Bayle

biomedical engineeringmolecular biologymolecular engineeringallogeneic car-t cellsmhc surface expressionvirus research

Inducible Myd88/Cd40 Synergizes With Il-15 to Enhance Antitumor Efficacy of Car-Nk Cells. Blood Advances (2020)

Xiaomei WangDaniel L. JasinskiJan L. MedinaDavid M. SpencerAaron E. FosterJ. Henri Bayle

molecular immunologytumor biologycancer immunotherapyclinical immunologyimmunologymedicinal researchantitumor efficacyimmunotherapycellular therapyimmune responsescellular immune responsescancer immunosurveillanceimmune checkpoint inhibitorsoncologycar-nk cells

Constitutively Active Myd88/Cd40 Costimulation Enhances Expansion and Efficacy of Chimeric Antigen Receptor T Cells Targeting Hematological Malignancies. Leukemia (2019)

Matthew R. Collinson-PautzWei-Chun ChangAn LuMariam KhalilJeannette W. CrisostomoPei-Yi LinAruna MahendravadaNicholas P. ShinnersMary E. BrandtMing ZhangMyLinh DuongJ. Henri BayleKevin M. SlawinDavid M. SpencerAaron E. Foster

t-regulatory cellcancer immunotherapyimmunologycell biologycell transplantationimmunotherapycellular therapybone marrow transplantationmedicinal researchcancer researchhematological malignanciescellular immune responsesmolecular biologyautoimmune diseasestherapeutic targetsantigen processingimmunological memoryleukemia

Characterization of Allogeneic T Cells Expressing Inducible Caspase-9 Following Adoptive Transfer in Children Receiving an Hla-Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Myeloid Malignancies. Blood (2018)

Joanne ShawXiaoou ZhouAn LuValentina BertainaDaria PagliaraMelissa AldingerDavid M. SpencerFranco LocatelliAaron Foster

adoptive transferimmunologystem cellshematologystem cell transplantationmyeloid malignancies

Differential Expression of Inducible Caspase-9 (Ic9) in Allogeneic T Cells Allows Selective Depletion of Activated T Cells Following Exposure to Rimiducid and Permits in Vivo Allodepletion. Blood (2018)

Xiaoou ZhouAn LuKelly L SharpMargie HarrisMadhavi AnumulaJ. BayleDavid M. SpencerAaron FosterJoanne Shaw

selective depletiont-regulatory cellvivo allodepletioncell signalingimmunologycell biologyblood cellshematologydifferential expressionimmune dysregulationimmune responsescellular immune responsesadaptive immune systemsystems biologygene expression

Regulated Natural Killer Cell Expansion and Anti-Tumor Activity With Inducible Myd88/Cd40. Blood (2018)

Xiaomei WangWei-Chun ChangDaniel L. JasinskiJan L. MedinaMing ZhangAaron FosterDavid M. SpencerJ. Henri Bayle

cancer immunotherapyimmunologyanti-tumor activitycellular immune responsesimmune responses

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David M Spencer

Visiting Professor

Baylor College of Medicine

Affiliations

Baylor College of Medicine Research

David M Spencer is currently serving as a Baylor College Of Medicine Research Visiting Professor at Baylor College of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

David M Spencer

Baylor College of Medicine

Visiting Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Enhanced Activation of Human Dendritic Cells by Inducible Cd40 and Toll-Like Receptor-4 Ligation. (2023)

Natalia LaptevaMamatha R. SeethammagariBrent A. HanksJianghong JiangJonathan M. LevittKevin M. SlawinDavid M. Spencer

cell signalingimmunologycell biologyimmune responseshuman dendritic cellsadaptive immune systemdata sciencecatalyst activationreceptorsinnate immune systemenhanced activation

Data From Versatile Prostate Cancer Treatment With Inducible Caspase and Interleukin-12. (2023)

Ekaterina Yu. NikitinaSmruti A. DesaiXiuqin ZhaoWeitao SongAnnie Z. LuoRama D. GangulaKevin M. SlawinDavid M. Spencer

inducible caspaseurologycancer treatmentprostate cancer

Supplementary Figures 1-3 From Ezc-Prostate Models Offer High Sensitivity and Specificity for Noninvasive Imaging of Prostate Cancer Progression and Androgen Receptor Action. (2023)

Mamatha R. SeethammagariXiaoming XieNorman M. GreenbergDavid M. Spencer

prostate cancer progressionezc-prostate modelsnoninvasive imagingprostate cancerandrogen receptor actionurologyhigh sensitivity

Abstract 2193: Small Molecule Inducible Myd88/Cd40 (Imc) in Car-T Cells Can Repolarize M2 Macrophage to an Anti-Tumor M1 Phenotype. Cancer Research (2020)

Xiaohong WangKonrad GabrusiewiczDavid M. SpencerAaron E. FosterJ. Henri Bayle

Engineering Tolerance Toward Allogeneic Car-T Cells by Regulation of Mhc Surface Expression With Human Herpes Virus-8 Proteins. Molecular Therapy (2020)

Xiaomei WangFabricio G. CabreraKelly L. SharpDavid M. SpencerAaron E. FosterJ. Henri Bayle

biomedical engineeringmolecular biologymolecular engineeringallogeneic car-t cellsmhc surface expressionvirus research

Inducible Myd88/Cd40 Synergizes With Il-15 to Enhance Antitumor Efficacy of Car-Nk Cells. Blood Advances (2020)

Xiaomei WangDaniel L. JasinskiJan L. MedinaDavid M. SpencerAaron E. FosterJ. Henri Bayle

Constitutively Active Myd88/Cd40 Costimulation Enhances Expansion and Efficacy of Chimeric Antigen Receptor T Cells Targeting Hematological Malignancies. Leukemia (2019)

Joanne ShawXiaoou ZhouAn LuValentina BertainaDaria PagliaraMelissa AldingerDavid M. SpencerFranco LocatelliAaron Foster

adoptive transferimmunologystem cellshematologystem cell transplantationmyeloid malignancies

Xiaoou ZhouAn LuKelly L SharpMargie HarrisMadhavi AnumulaJ. BayleDavid M. SpencerAaron FosterJoanne Shaw

Regulated Natural Killer Cell Expansion and Anti-Tumor Activity With Inducible Myd88/Cd40. Blood (2018)

Xiaomei WangWei-Chun ChangDaniel L. JasinskiJan L. MedinaMing ZhangAaron FosterDavid M. SpencerJ. Henri Bayle

cancer immunotherapyimmunologyanti-tumor activitycellular immune responsesimmune responses

1
2
3
4
5
16
10 / page

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cellular therapy

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immunomodulation

tumor immunobiology

Zihai Li

Institution

Medical University of South Carolina

immunology

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brain tumor research

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