Faculty

Institution

Unit

Venue

David Farquhar

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Experimental Therapeutics

NoneDavid Farquhar is currently serving as a Experimental Therapeutics faculty at The University of Texas Md Anderson Cancer Center.

Honors

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Experiences

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Education

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David Farquhar

The University of Texas MD Anderson Cancer Center

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pharmacology biochemistry medicinal chemistry pharmaceutical chemistry pharmacological research enzyme inhibition drug development drug discovery oncology drug metabolism molecular biology therapeutic targets medicinal research medicine biochemical sciences bioorganic chemistry molecular pharmacology chemical synthesis pharmacotherapy applied pharmacology leukemia natural product research oncogenes gynecologic oncology pharmaceutical sciences enzyme catalysis cancer treatment biopolymers biological macromolecules pharmaceutics cancer cells pharmacognosy controlled release novel therapies anti-cancer agents pharmacological studies pharmacokinetics experimental pharmacology human retrovirus polymer-drug conjugate pharmacological agents synthetic chemistry biochemical interaction bioconjugation biochemical pharmacology cellular neurobiology neurotransmission brain science neural science brain stimulation therapeutic efficacy bioceramics biomineralization biocompatible materials surface reactivity rational drug design mutagenesis toxicological mechanism drug-induced liver injury oligonucleotides hematological malignancies antitumor efficacy bacillus calmette-guérin treatment drug-metabolizing enzymes reversible phosphate-protective groups superior therapeutic profile poly-l-glutamic acid-paclitaxel copolymer human ovarian carcinoma membrane-permeating prodrug cyclophosphamide resistance human urinary metabolites methyl isocyanate antitumor agent caracemide potential ddump prodrugs

Notable Scholarly Works

Notable Federal Grants

Collaborators

Targeted Disruption of Cocaine-Activated Nucleus Accumbens Neurons Prevents Context-Specific Sensitization. Nature Neuroscience (2009)

Eisuke KoyaSam A GoldenBrandon K HarveyDanielle H Guez-BarberAlexander BerkowDanielle E SimmonsJennifer M BossertSunila G NairJamie L UejimaMarcelo T MarinTimothy B MitchellDavid FarquharSukhen C GhoshBrandi J MattsonBruce T Hope

neurologyneural sciencepsychiatrysystems neuroscienceneuropharmacologycellular neurobiologycognitive neuroscienceneuroscienceneurotransmissionbrain sciencebrain stimulationsignal transductioncentral nervous system

N,N-Dimethylsphingosine Conjugates of Poly-L-Glutamic Acid: Synthesis, Characterization, and Initial Biological Evaluation. Bioorganic & Medicinal Chemistry Letters (2008)

natural product researchpharmaceutical chemistrybioconjugationmedicinal chemistrybiochemistrybioorganic chemistry

Cd44-Targeted Hyaluronic Acid-Paclitaxel (Ha-Txl) Copolymer for Treatment of Human Ovarian Carcinoma Xenografts. Molecular Cancer Therapeutics (2007)

Jim KlostergaardEdmond AuzenneSukhen GhoshMojgan KhodadadianBelinda RiveraDavid FarquharRoger PriceMurali RavooriVikas KundraRalph Freedman

gynecologic oncologytumor targetingmolecular cancerbiomedical engineeringcancer researchtherapeutic targetsovarian cancercancer treatment

Hyaluronic Acid- Paclitaxel: Antitumor Efficacy Against Cd44(+) Human Ovarian Carcinoma Xenografts. Neoplasia (2007)

Edmond AuzenneSukhen C. GhoshMojgan KhodadadianBelinda RiveraDavid FarquharRoger E. PriceMurali RavooriVikas KundraRalph S. FreedmanJim Klostergaard

gynecologic oncologyoncogenescancer treatmentmedicinal researchnovel therapiesantitumor efficacygynecologycancer discoverypharmacologygynecologic cancerstherapeutic efficacyovarian cancerpharmacotherapyoncology

N,N -Dimethylsphingosine−Coumarin: Synthesis, Chemical Characterization, and Biological Evaluation. Bioconjugate Chemistry (2007)

drug developmentpharmaceutical chemistrydrug analysisbioconjugationmedicinal chemistrysmall moleculesbiochemistrychemical biologychemical synthesispharmacology

Bis(Carbamoyloxymethyl) Esters of 2?,3?-Dideoxyuridine 5?-Monophosphate (Ddump) as Potential Ddump Prodrugs. Pharmaceutical Research (2005)

Saeed R. KhanSrinivas K. KumarDavid Farquhar

potential ddump prodrugsepidemiologypharmaceutical chemistrypharmaceutical sciencesmedicinal researchmedicinepharmacologytherapeutic targetsdrug discoverypharmacological researchpharmaceutical research

Bis(Pivaloyloxymethyl) Thymidine 5′-Phosphate is a Cell Membrane-Permeable Precursor of Thymidine 5′-Phosphate in Thymidine Kinase Deficient Ccrf Cem Cells. Biochemical Pharmacology (2005)

protein phosphorylationcell biologybiochemistrymembrane biologypharmacologycellular biochemistry

Antitumor Activity of Hydrophilic Paclitaxel Copolymer Prodrug Using Locoregional Delivery in Human Orthotopic Non–Small Cell Lung Cancer Xenograft Models. Clinical Cancer Research (2004)

controlled releasedrug deliverypharmaceuticslung cancercancer researchpharmacologypolymer-drug conjugateoncology

Cheminform Abstract: Facile Selective Cleavage of a Myo‐Inositol Trans‐Isopropylidene Acetal in the Presence of a Cis‐Isopropylidene Acetal.. ChemInform (2002)

cheminformaticschemistryorganic chemistrystereoselective synthesis

Facile Selective Cleavage of a Myo-Inositol Trans-Isopropylidene Acetal in the Presence of a Cis-Isopropylidene Acetal. Tetrahedron Letters (2002)

organic chemistry frontiermedicinal chemistrychemistryorganic chemistrystereoselective synthesis

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David Farquhar

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Experimental Therapeutics

NoneDavid Farquhar is currently serving as a Experimental Therapeutics faculty at The University of Texas Md Anderson Cancer Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

David Farquhar

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Targeted Disruption of Cocaine-Activated Nucleus Accumbens Neurons Prevents Context-Specific Sensitization. Nature Neuroscience (2009)

N,N-Dimethylsphingosine Conjugates of Poly-L-Glutamic Acid: Synthesis, Characterization, and Initial Biological Evaluation. Bioorganic & Medicinal Chemistry Letters (2008)

natural product researchpharmaceutical chemistrybioconjugationmedicinal chemistrybiochemistrybioorganic chemistry

Cd44-Targeted Hyaluronic Acid-Paclitaxel (Ha-Txl) Copolymer for Treatment of Human Ovarian Carcinoma Xenografts. Molecular Cancer Therapeutics (2007)

Jim KlostergaardEdmond AuzenneSukhen GhoshMojgan KhodadadianBelinda RiveraDavid FarquharRoger PriceMurali RavooriVikas KundraRalph Freedman

gynecologic oncologytumor targetingmolecular cancerbiomedical engineeringcancer researchtherapeutic targetsovarian cancercancer treatment

Hyaluronic Acid- Paclitaxel: Antitumor Efficacy Against Cd44(+) Human Ovarian Carcinoma Xenografts. Neoplasia (2007)

Edmond AuzenneSukhen C. GhoshMojgan KhodadadianBelinda RiveraDavid FarquharRoger E. PriceMurali RavooriVikas KundraRalph S. FreedmanJim Klostergaard

N,N -Dimethylsphingosine−Coumarin: Synthesis, Chemical Characterization, and Biological Evaluation. Bioconjugate Chemistry (2007)

drug developmentpharmaceutical chemistrydrug analysisbioconjugationmedicinal chemistrysmall moleculesbiochemistrychemical biologychemical synthesispharmacology

Bis(Carbamoyloxymethyl) Esters of 2?,3?-Dideoxyuridine 5?-Monophosphate (Ddump) as Potential Ddump Prodrugs. Pharmaceutical Research (2005)

Saeed R. KhanSrinivas K. KumarDavid Farquhar

Bis(Pivaloyloxymethyl) Thymidine 5′-Phosphate is a Cell Membrane-Permeable Precursor of Thymidine 5′-Phosphate in Thymidine Kinase Deficient Ccrf Cem Cells. Biochemical Pharmacology (2005)

protein phosphorylationcell biologybiochemistrymembrane biologypharmacologycellular biochemistry

Antitumor Activity of Hydrophilic Paclitaxel Copolymer Prodrug Using Locoregional Delivery in Human Orthotopic Non–Small Cell Lung Cancer Xenograft Models. Clinical Cancer Research (2004)

controlled releasedrug deliverypharmaceuticslung cancercancer researchpharmacologypolymer-drug conjugateoncology

Cheminform Abstract: Facile Selective Cleavage of a Myo‐Inositol Trans‐Isopropylidene Acetal in the Presence of a Cis‐Isopropylidene Acetal.. ChemInform (2002)

cheminformaticschemistryorganic chemistrystereoselective synthesis

Facile Selective Cleavage of a Myo-Inositol Trans-Isopropylidene Acetal in the Presence of a Cis-Isopropylidene Acetal. Tetrahedron Letters (2002)

organic chemistry frontiermedicinal chemistrychemistryorganic chemistrystereoselective synthesis

1
2
3
4
5
10 / page