David A. Jaffray

David A. Jaffray is a Senior Professor at The University of Texas MD Anderson Cancer Center. His research integrates radiation oncology, medical imaging, and cancer care, with a focus on precision lung cancer management. His recent work spans CT-based deep foundation models for predicting immune checkpoint inhibitor-induced pneumonitis, causal AI and radiomic analysis for optimizing immunotherapy and stereotactic ablative radiotherapy in early-stage non-small cell lung cancer, and radiomics for dynamic risk prediction in USPSTF-ineligible patients. He has contributed to studies on SARS-CoV-2 mRNA vaccines sensitizing tumors to immune checkpoint blockade and machine-learning strategies for adapting immunotherapy in metastatic NSCLC. His collaborations advance expanded access to radiology and data safety in oncology.