Faculty

Institution

Unit

Venue

Dan S. Gombos

Professor

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Clinical Cancer Genetics

Department Of Head And Neck Surgery

Department Of Ophthalmology

Department Of Oral Oncology

The University of Texas MD Anderson Cancer Center

Dan S. Gombos is a Professor at The University of Texas MD Anderson Cancer Center, specializing in ophthalmology and oncology. His research focuses on ocular pathology, particularly uveal melanoma, neuro-ophthalmology, and ocular graft-versus-host disease. Recent breakthroughs include studies on early genetic evolution of driver mutations in uveal melanoma (Nature Communications, 2025) and a Phase I trial of hydroxychloroquine to enhance palbociclib and letrozole efficacy in ER+/HER2− breast cancer (npj Breast Cancer, 2025). He has also contributed to consensus guidelines on metastatic uveal melanoma surveillance (Cancers, 2025). His work integrates dermatology and cancer research, with international collaborations advancing ocular disease diagnosis and management.

Honors

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Dan S. Gombos

The University of Texas MD Anderson Cancer Center

Professor

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ophthalmology oncology ocular disease melanoma neuro-ophthalmology dermatology radiation oncology ophthalmology retina ocular surface cancer research medicine ocular pathology histopathology cancer treatment metastasis uveal melanoma cancer care surgical oncology cancer cells skin cancer cancer immunotherapy immunotherapy oncogenes radiation therapy vitreous body cancer imaging pediatric ophthalmology clinical research radiation leukemia clinical radiation oncology oculoplastics photocarcinogenesis metastatic uveal melanoma medicinal research ocular tissues retina breast oncology aqueous humour malignant disease lymphoid neoplasia von hippel-lindau disease intraocular retinoblastoma cellular therapy dermatological treatment brachytherapy cancer biology primary intraocular lymphoma clinical rheumatology oral biology neuroradiology thoracic oncology dosimetry radiation exposure radiation biology clinical immunology covid-19 pandemic treatment effects experimental ophthalmology therapeutic efficacy eye health proton therapy pilot study toxicity outcomes targeted cancer therapy phase ii study cataracts prognostic evaluation cohort studies pilot trial sunitinib therapy proton beam therapy tantalum markers definitive treatment comparative outcomes immune profiling

Notable Scholarly Works

Notable Federal Grants

Collaborators

Acral Lentiginous Melanoma Metastases to the Vitreous Masquerading as Uveitis: A Case Report. American Journal of Ophthalmology Case Reports (2026)

melanomaophthalmologyneuro-ophthalmologyocular pathologysurgical pathologyvitreous body

Current Diagnosis and Management of Ocular Graft-Versus-Host Disease at a Tertiary Cancer Center. Journal of Clinical Medicine (2026)

glaucomaorgan transplantationophthalmologyneuro-ophthalmologyocular graft-versus-host diseaseocular surfaceoculoplasticscurrent diagnosistertiary cancer centerophthalmology retinaocular pathologypathologyocular disease

Abstract P4-08-19: Phase I Safety and Efficacy Study of Autophagy Inhibition to Augment the Antiproliferative and Biological Effects of Low Dose Palbociclib Plus Letrozole in Estrogen Receptor-Positive, Her2-Negative Metastatic Breast Cancer (Mbc). Clinical Cancer Research (2025)

autophagy inhibitionmetastasispharmacologylow dose palbociclibbiological effectsmolecular cancerpharmacotherapytherapeutic targetsbreast oncologyanti-cancer agentsbreast cancermedicinal researchcancer treatmentcell biology

Corrigendum. Ophthalmology (2025)

Early Genetic Evolution of Driver Mutations in Uveal Melanoma. Nature Communications (2025)

genome biologycarcinogenesisgenetic evolutionmelanomageneticsphotocarcinogenesismolecular geneticsoncogeneshuman genetics

Metastatic Uveal Melanoma Surveillance: A Delphi Panel Consensus. Cancers (2025)

dermatologymetastasisophthalmologymelanomacancer imagingoncologydelphi panel consensus

Phase I Trial of Hydroxychloroquine to Enhance Palbociclib and Letrozole Efficacy in Er+/Her2− Breast Cancer. npj Breast Cancer (2025)

pharmacologyer+/her2− breast cancerfuture medicinal chemistryradiation oncologycancer researchmolecular cancerletrozole efficacypharmacotherapybreast canceroncologycancer treatmentbreast oncology

Topical Spironolactone in Ocular Graft-Versus-Host Disease. Medical Research Archives (2025)

glaucomaophthalmologyocular surfacetopical spironolactoneocular pathologyocular diseaseocular surface physiology

15-Gene Expression Profile and Prame as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (Coog2.1). Journal of Clinical Oncology (2024)

J. William HarbourZelia M. CorreaAmy C. ScheflerPrithvi MruthyunjayaMiguel A. MaterinThomas A. AabergAlison H. SkaletDavid A. ReichsteinEzekiel WeisIvana K. KimTimothy S. FullerHakan DemirciKisha D. PiggottBasil K. WilliamsEugene ShildkrotAntonio CaponeScott C. OliverScott D. WalterJohn MasonDevron H. CharMichael AltaweelJill R. WellsJay S. DukerPeter G. HovlandDan S. GombosTony TsaiCameron JavidBrian P. MarrAng GaoChristina L. DecaturJames J. DollarStefan KurtenbachSong Zhang

gene expressionmelanomaophthalmologyuveal melanomacancer researchprognostic evaluationbiostatisticsmolecular biologyoncologyclinical researchintegrated prognostic testocular diseaseocular pathologycohort studiesmolecular medicine

Abstract Po5-06-02: Phase II Trial of Combination of Atezolizumab, Cobimetinib and Eribulin (Ace) or Atezolizumab and Eribulin (Ae) in Patients With Metastatic Inflammatory Breast Cancer (Ibc): Clinical Data of Both Cohorts. Cancer Research (2024)

clinical datamedicinepharmacologymetastasiscancer caremolecular cancerimmune checkpoint inhibitorspharmacotherapytherapeutic targetsclinical trialsphase ii trialbreast canceroncologycancer treatmentabstract po5-06-02breast oncology

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Dan S. Gombos

Professor

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Clinical Cancer Genetics

Department Of Head And Neck Surgery

Department Of Ophthalmology

Department Of Oral Oncology

The University of Texas MD Anderson Cancer Center

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Dan S. Gombos

The University of Texas MD Anderson Cancer Center

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Acral Lentiginous Melanoma Metastases to the Vitreous Masquerading as Uveitis: A Case Report. American Journal of Ophthalmology Case Reports (2026)

melanomaophthalmologyneuro-ophthalmologyocular pathologysurgical pathologyvitreous body

Current Diagnosis and Management of Ocular Graft-Versus-Host Disease at a Tertiary Cancer Center. Journal of Clinical Medicine (2026)

Corrigendum. Ophthalmology (2025)

Early Genetic Evolution of Driver Mutations in Uveal Melanoma. Nature Communications (2025)

genome biologycarcinogenesisgenetic evolutionmelanomageneticsphotocarcinogenesismolecular geneticsoncogeneshuman genetics

Metastatic Uveal Melanoma Surveillance: A Delphi Panel Consensus. Cancers (2025)

dermatologymetastasisophthalmologymelanomacancer imagingoncologydelphi panel consensus

Phase I Trial of Hydroxychloroquine to Enhance Palbociclib and Letrozole Efficacy in Er+/Her2− Breast Cancer. npj Breast Cancer (2025)

pharmacologyer+/her2− breast cancerfuture medicinal chemistryradiation oncologycancer researchmolecular cancerletrozole efficacypharmacotherapybreast canceroncologycancer treatmentbreast oncology

Topical Spironolactone in Ocular Graft-Versus-Host Disease. Medical Research Archives (2025)

glaucomaophthalmologyocular surfacetopical spironolactoneocular pathologyocular diseaseocular surface physiology

15-Gene Expression Profile and Prame as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (Coog2.1). Journal of Clinical Oncology (2024)

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5
15
10 / page