Faculty

Institution

Unit

Venue

Collin David Kieffer

Assistant Professor of Microbiology Assistant Professor

UIUC

Affiliations

College of Liberal Arts & Sciences

School of Molecular & Cellular Biology

Department of Microbiology

Collin David Kieffer is currently serving as a College Of Liberal Arts & Sciences Assistant Professor of Microbiology Assistant Professor at Uiuc.

Honors

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Experiences

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Education

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Collin David Kieffer

UIUC

Assistant Professor of Microbiology Assistant Professor

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medical virology immunology virus research hiv general virology human retrovirus cell biology virology immune responses antiviral research immunity (medicine) molecular biology antiviral responses infectious diseases viral structural protein chronic viral infections biological imaging structural molecular biology protein structure sars-cov-2 biomolecular structure viral replication structural biology protein science molecular cell biology biomedical analysis molecular physiology cell research vaccine design mammary gland cellular immune responses electron tomography aryl hydrocarbon receptor biological chemistry biological macromolecules histopathology developmental system matrix biology virus structure molecular recognition yeast mucosal immunology vaccine development viral dynamics cell-matrix interactions cell adhesion endocrine disruptors toxicological mechanism digestive tract molecular nutrition gut barrier mechanisms of action pharmacological agents immune dysregulation tissue imaging bioimage analysis virus-host interactions viral pathogenesis viral evolution immunologic mechanisms immunopathology viral oncology electron cryotomography immature hiv-1 virions sp1 gag shells escrt-iii recognition lysosomal protein targeting hiv-1 budding distinct modes yeast vps4 oligomerization hiv-1 infection image hiv-1 prefusion conformation prefusion stabilization free virions longitudinal imaging antiviral therapy virus transmission viral diagnostics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Hiv Integration Into the Pten Gene and Its Tumor Microenvironment Implications for Lung Cancer. Current Oncology (2025)

Davey M. SmithElizabeth F. RowlandSara GianellaSandip Pravin PatelStephanie SolsoCheryl DullanoRobert DeissDaria WellsCaroline IgnacioGemma CaballeroMagali PorrachiaCollin KiefferAntoine Chaillon

hiv integrationlung cancertumor biologyhivmedical virologyoncogenesviral oncologyimmunologyhuman retroviruspten genetumor microenvironmentpathology

Monocyte to Macrophage Differentiation and Changes in Cellular Redox Homeostasis Promote Cell Type-Specific Hiv Latency Reactivation. Proceedings of the National Academy of Sciences (2024)

Alexandra BlancoRobert A. CoronadoNeha ArunKelly MaRoy D. DarCollin Kieffer

hiv latency dynamicshivimmune responsesimmune dysregulationantiviral researchinflammationhiv latency regulationcell biologycell signalingmedical virologychronic viral infectionsimmunologyantiviral responsescell researchhiv latency modelhuman retroviruscellular immune responsesgeneral virology

Seasonal Influenza a Virus Lineages Exhibit Divergent Abilities to Antagonize Interferon Induction and Signaling. PLoS Pathogens (2024)

Joel Rivera-CardonaNeeha KakuturuElizabeth F. RowlandQi Wen TeoElizabeth A. ThayerTimothy J. C. TanJiayi SunCollin KiefferNicholas C. WuChristopher B. Brooke

virologyimmune responsessingle cell studiesantiviral researchinfluenzainfectious diseasesmedical virologyvirus-host interactionsimmunity (medicine)immunologyantiviral responsesviral evolutionviral pathogenesissingle cell levelpathogenesisgeneral virologyseasonal influenzavirus research

A Protective Role for the Lectin Cd169/Siglec-1 During Sars-Cov-2 Infection. SSRN Electronic Journal (2023)

Irfan UllahMark LadinskyLokesh SharmaZoela GilaniElizabeth F. RowlandMatthias MackCollin KiefferPamela J. BjorkmanWalther MothesPriti KumarPradeep Uchil

immune responsesimmunologic mechanismsantiviral researchinflammationinfectious diseasesvirus capturemedical virologysars-cov-2inflammatory responseimmunity (medicine)immunologyantiviral responsesvirus clearanceimmunopathologygeneral virologyvirus research

High-Throughput Identification of Prefusion-Stabilizing Mutations in Sars-Cov-2 Spike. Nature Communications (2023)

Timothy J. C. TanZongjun MouRuipeng LeiWenhao O. OuyangMeng YuanGe SongRaiees AndrabiIan A. WilsonCollin KiefferXinghong DaiKenneth A. MatreyekNicholas C. Wu

virologycovid-19antiviral researchvaccine developmentprefusion stabilizationviral structural proteinprefusion conformationmedical virologysars-cov-2immunologymolecular biologyvaccine designgeneral virologyvirus research

Probing the Biophysical Constraints of Sars-Cov-2 Spike N-Terminal Domain Using Deep Mutational Scanning. Science Advances (2022)

Wenhao O. OuyangTimothy J.C. TanRuipeng LeiGe SongCollin KiefferRaiees AndrabiKenneth A. MatreyekNicholas C. Wu

virologyimmune responsesvacciness protein expressionantiviral researchviral structural proteindeep mutational scanningmedical virologystructural molecular biologysars-cov-2ntd residuesimmunologyimmunity (medicine)molecular biologyvaccine designgeneral virologyvirus research

3D Visualization of Immune Cell Populations in Hiv-Infected Tissues via Clearing, Immunostaining, Confocal, and Light Sheet Fluorescence Microscopy. Journal of Visualized Experiments (2021)

Tongyu ZhangAuroni GuptaDeborah FrederickLaura LaymanDavey M. SmithSara GianellaCollin Kieffer

hivmicroscopyconfocal microscopybiomedical imagingimmune cell populationscell biologymedical virologybiological imagingimmunologyimage analysistissue imagingbiomedical analysishiv-infected tissuesbioimage analysis

Deletion of Intestinal Shp Impairs Short-Term Response to Cholic Acid Challenge in Male Mice. Endocrinology (2021)

James T NguyenRyan RiessenTongyu ZhangCollin KiefferSayeepriyadarshini Anakk

molecular gastroenterologymetabolic pathwayscholic acid challengemetabolismgastroenterologydigestive diseasesishpko micecell signalingbile acidimmunologyphysiologynutritional biochemistrymolecular nutritioncell metabolismgut barriermolecular physiologydigestive tract

In Vitro Characterization of Engineered Red Blood Cells as Viral Traps Against Hiv-1 and Sars-Cov-2. Molecular Therapy — Methods & Clinical Development (2021)

Magnus A.G. HoffmannCollin KiefferPamela J. Bjorkman

hivimmune responsesfusion proteinantiviral researchbiomolecular engineeringviral structural proteincell biologymedical virologycd4-gpa expressionimmunologyviral replicationantiviral responseshuman retrovirusred blood cellsgeneral virologyvirus research

In Vitro Characterization of Engineered Red Blood Cells as Potent Viral Traps Against Hiv-1 and Sars-Cov-2. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Magnus A. G. HoffmannCollin KiefferPamela J. Bjorkman

hivantiviral researchbiomolecular engineeringengineered rbcscell biologymedical virologysynthetic immunologycd4-gpa expressionimmunologyviral replicationantiviral responsesgene therapyhuman retrovirusred blood cellsvirus research

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Collin David Kieffer

Assistant Professor of Microbiology Assistant Professor

UIUC

Affiliations

College of Liberal Arts & Sciences

School of Molecular & Cellular Biology

Department of Microbiology

Collin David Kieffer is currently serving as a College Of Liberal Arts & Sciences Assistant Professor of Microbiology Assistant Professor at Uiuc.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Collin David Kieffer

UIUC

Assistant Professor of Microbiology Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Hiv Integration Into the Pten Gene and Its Tumor Microenvironment Implications for Lung Cancer. Current Oncology (2025)

Davey M. SmithElizabeth F. RowlandSara GianellaSandip Pravin PatelStephanie SolsoCheryl DullanoRobert DeissDaria WellsCaroline IgnacioGemma CaballeroMagali PorrachiaCollin KiefferAntoine Chaillon

hiv integrationlung cancertumor biologyhivmedical virologyoncogenesviral oncologyimmunologyhuman retroviruspten genetumor microenvironmentpathology

Monocyte to Macrophage Differentiation and Changes in Cellular Redox Homeostasis Promote Cell Type-Specific Hiv Latency Reactivation. Proceedings of the National Academy of Sciences (2024)

Alexandra BlancoRobert A. CoronadoNeha ArunKelly MaRoy D. DarCollin Kieffer

Seasonal Influenza a Virus Lineages Exhibit Divergent Abilities to Antagonize Interferon Induction and Signaling. PLoS Pathogens (2024)

Joel Rivera-CardonaNeeha KakuturuElizabeth F. RowlandQi Wen TeoElizabeth A. ThayerTimothy J. C. TanJiayi SunCollin KiefferNicholas C. WuChristopher B. Brooke

A Protective Role for the Lectin Cd169/Siglec-1 During Sars-Cov-2 Infection. SSRN Electronic Journal (2023)

Irfan UllahMark LadinskyLokesh SharmaZoela GilaniElizabeth F. RowlandMatthias MackCollin KiefferPamela J. BjorkmanWalther MothesPriti KumarPradeep Uchil

High-Throughput Identification of Prefusion-Stabilizing Mutations in Sars-Cov-2 Spike. Nature Communications (2023)

Timothy J. C. TanZongjun MouRuipeng LeiWenhao O. OuyangMeng YuanGe SongRaiees AndrabiIan A. WilsonCollin KiefferXinghong DaiKenneth A. MatreyekNicholas C. Wu

Probing the Biophysical Constraints of Sars-Cov-2 Spike N-Terminal Domain Using Deep Mutational Scanning. Science Advances (2022)

Wenhao O. OuyangTimothy J.C. TanRuipeng LeiGe SongCollin KiefferRaiees AndrabiKenneth A. MatreyekNicholas C. Wu

3D Visualization of Immune Cell Populations in Hiv-Infected Tissues via Clearing, Immunostaining, Confocal, and Light Sheet Fluorescence Microscopy. Journal of Visualized Experiments (2021)

Tongyu ZhangAuroni GuptaDeborah FrederickLaura LaymanDavey M. SmithSara GianellaCollin Kieffer

Deletion of Intestinal Shp Impairs Short-Term Response to Cholic Acid Challenge in Male Mice. Endocrinology (2021)

James T NguyenRyan RiessenTongyu ZhangCollin KiefferSayeepriyadarshini Anakk

In Vitro Characterization of Engineered Red Blood Cells as Viral Traps Against Hiv-1 and Sars-Cov-2. Molecular Therapy — Methods & Clinical Development (2021)

Magnus A.G. HoffmannCollin KiefferPamela J. Bjorkman

In Vitro Characterization of Engineered Red Blood Cells as Potent Viral Traps Against Hiv-1 and Sars-Cov-2. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Magnus A. G. HoffmannCollin KiefferPamela J. Bjorkman

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