Faculty

Institution

Unit

Venue

Clark, Abbot F

University of North Texas Health Science Center

Affiliations

College of Biomedical and Translational Sciences

Physiology and Anatomy

University of North Texas Health Science Center

College of Public Health

Focused on Resources for her Health Education and Research (FOR HER)

Physical Medicine Institute

Texas Prevention Institute (TPI)

School Of Public Health

Department Of Behavioral And Community Health

Department Of Behavioraland Community Health

Department Of Environmental And Occupational Health

Department Of Health Administration And Health Policy

Department Of Health Administration And Policy

Department Of Health Behavior And Health Systems

Department Of Health Management And Policy

Texas College of Osteopathic Medicine

Physical Medicine Institute

NoneClark, Abbot F is currently serving as a College Of Biomedical And Translational Sciences faculty at University of North Texas Health Science Center.

Honors

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Experiences

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Education

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Clark, Abbot F

University of North Texas Health Science Center

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ophthalmology cell biology glaucoma ophthalmology retina trabecular meshwork cellular physiology ocular disease neuro-ophthalmology ocular surface visual science retina experimental ophthalmology tissue (biology) cell signaling neuroscience signal transduction matrix biology ocular tissues cell research molecular cell biology optic nerve molecular biology gene expression receptors glucocorticoids ganglion cell extracellular matrix molecular physiology vascular biology vision research ocular pathology ocular surface physiology molecular neurodegeneration aqueous humour cell-matrix interactions mammalian biology signaling pathways cell growth molecular neurobiology bone research human tissues lamina cribrosa cells trabecular meshwork cells bone morphogenic protein intraocular pressure optic nerve crush retinal ganglion cells oral biology receptor (biochemistry) cross-linked actin networks medicinal research cellular neurobiology eye health cell biomechanics human trabecular meshwork ocular hypertension clinical investigation experimental medicine cell culture protein expression rna biology crispr mouse model optic nerve head glucocorticoid-induced ocular hypertension novel therapies experiment design neuroprotection clinical medicine connective tissue disease tissue culture glucocorticoid receptor β bone morphogenetic proteins aqueous humor dynamics tissue transglutaminase expression angiostatic activity

Notable Scholarly Works

Notable Federal Grants

Collaborators

Pharmacological Restoration of Impaired Autophagy in Retinal Ganglion Cells Prevents Abnormal Mitochondrial Accumulation and Glaucomatous Neurodegeneration. Molecular Neurodegeneration (2026)

mitochondrial functionneurodegenerative diseasesneuroscienceglaucomaautophagyophthalmology retinaretinaophthalmologymolecular neurodegenerationmolecular medicineganglion cell

Biodistribution of Reconstituted High-Density Lipoprotein Nanoparticles for Targeted Delivery to Retinal Ganglion Cells. Journal of Ocular Pharmacology and Therapeutics (2025)

nanoparticlespharmaceutical nanotechnologynano-drug deliverytargeted deliveryophthalmology retinabiomedical engineeringtherapeutic nanomaterialsophthalmologynanoparticle researchcontrolled releasedrug deliveryretinal ganglion cells

C/Ebp Homologous Protein Expression in Retinal Ganglion Cells Induces Neurodegeneration in Mice. International Journal of Molecular Sciences (2025)

molecular neuroscienceneuronsmolecular cell biologycell signalingneuro-ophthalmologyneuroscienceophthalmology retinaretinamolecular neurobiologysignal transductionophthalmologymolecular neurodegenerationphotoreceptor cellscell deathcellular physiologyganglion cell

Genetic and Pharmacological Correction of Impaired Mitophagy in Retinal Ganglion Cells Rescues Glaucomatous Neurodegeneration. bioRxiv (Cold Spring Harbor Laboratory) (2025)

ocular diseasegeneticsglaucomatous neurodegenerationoptogeneticsmolecular neuroscienceneurodegenerative diseasescell biologyneuro-ophthalmologyautophagyglaucomaophthalmology retinaophthalmologymolecular neurodegenerationimpaired mitophagymolecular medicineganglion cellretinal ganglion cells

Mechanistic Insights Into Glucocorticoid-Induced Ocular Hypertension Using Differences in Mouse Strain Responsiveness. American Journal Of Pathology (2025)

receptorsocular diseasetrabecular meshworkmouse strain responsivenessendocrinologyneuro-ophthalmologyglucocorticoidshypertensionophthalmology retinaphysiologyophthalmologyaqueous humourexperimental ophthalmologyocular surfacemechanistic insights

PHENETHYLAMINYLATION: Preliminary in Vitro Evidence for the Covalent Transamidation of Psychedelic Phenethylamines to Glial Proteins Using 3,5-Dimethoxy-4-(2-Propynyloxy)-Phenethylamine as a Model Compound. bioRxiv (Cold Spring Harbor Laboratory) (2025)

neurochemistrypharmaceutical chemistryneuropharmacologypharmacological researchchemical biologypsychedelic phenethylaminescheminformaticsmolecular psychiatryexperimental pharmacologybiochemistrypharmacologyneurotransmittersvitro evidencemolecular pharmacologycovalent transamidationneuropsychopharmacology

Therapeutic Mrna Delivery of Crispr-Cas9 to the Trabecular Meshwork Reverses Ocular Hypertension in Myocilin Glaucoma. Molecular Therapy — Methods & Clinical Development (2025)

therapeutic mrna deliverygene expressiontrabecular meshworkcrisprmolecular cell biologygene editingglaucomaophthalmology retinamyocilin glaucomaophthalmologymolecular medicinemolecular biologygene therapyocular surfacegenetic engineering

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches. Investigative Ophthalmology & Visual Science (2024)

Ted S. AcottMichael P. FautschWeiming MaoC. Ross EthierAlex S. HuangMary J. KelleyMini AgaSanjoy K. BhattacharyaTerete BorrasDiane BovenkampUttio Roy ChowdhuryAbbot F. ClarkMohammed I. DibasYiqin DuMichael H. ElliottJennifer A. FaralliHaiyan GongSamuel HerbergMurray A. JohnstonePaul L. KaufmanKate E. KellerRuth A. KellyDavid KrizajMarkus H. KuehnHoi Lam LiRaquel LiebermanShan C. LinYutao LiuFiona S. McDonnellColleen M. McDowellGillian J. McLellanPhilip MzykKayarat Saidas NairDarryl R. OverbyDonna M. PetersVijayKrishna RaghunathanPonugoti Vasantha RaoGavin W. RoddyNajam A. SharifMyoung Sup ShimYang SunBenjamin R. ThomsonCarol B. TorisColin E. WilloughbyHao F. ZhangThomas F. FreddoRudolf FuchshoferKamisha R. HillAlireza KarimiKrishnakumar KizhatilCasey C. KopcyznskiPaloma LitonGaurang PatelMichael PengPadmanabhan P. PattabiramanGanesh PrasannaEster Reina-TorresE. Griffen SamplesJohn R. SamplesCynthia L. SteelClemens A. StrohmaierPreeti SubramanianChenna Kesavulu SugaliJoseph van Batenburg-SherwoodCydney WongHannah YoungbloodGulab S. ZodeElizabeth WhiteW. Daniel Stamer

visual scienceocular tissuesintraocular pressure regulationvision researchocular surface physiologyophthalmologyoutflow facilityexperimental ophthalmologyocular surfacemedical optical imaging

Evaluation of Cross-Linked Actin Networks (Clans) in Human Trabecular Meshwork Cells and Tissues. Methods in molecular biology (2024)

Pinkal D PatelAbbot F Clark

tissue engineeringnetwork analysisbiomedical imagingresearch designtrabecular meshworkcross-linked actin networkshuman tissuescell biologyneurosciencebiomedical engineeringtissue (biology)

Lentiviral Mediated Delivery of Crispr/Cas9 Reduces Intraocular Pressure in a Mouse Model of Myocilin Glaucoma. Scientific Reports (2024)

Shruti V. PatilBalasankara Reddy KaipaSujata RanshingYogapriya SundaresanJ. Cameron MillarBhavani NagarajanCharles KiehlbauchQihong ZhangAnkur JainCharles C. SearbyTodd E. ScheetzAbbot F. ClarkVal C. SheffieldGulab S. Zode

geneticscrisprglaucomapharmacologymyocilin glaucomaophthalmologymouse model

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Clark, Abbot F

University of North Texas Health Science Center

Affiliations

College of Biomedical and Translational Sciences

Physiology and Anatomy

University of North Texas Health Science Center

College of Public Health

Focused on Resources for her Health Education and Research (FOR HER)

Physical Medicine Institute

Texas Prevention Institute (TPI)

School Of Public Health

Department Of Behavioral And Community Health

Department Of Behavioraland Community Health

Department Of Environmental And Occupational Health

Department Of Health Administration And Health Policy

Department Of Health Administration And Policy

Department Of Health Behavior And Health Systems

Department Of Health Management And Policy

Texas College of Osteopathic Medicine

Physical Medicine Institute

NoneClark, Abbot F is currently serving as a College Of Biomedical And Translational Sciences faculty at University of North Texas Health Science Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Clark, Abbot F

University of North Texas Health Science Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Pharmacological Restoration of Impaired Autophagy in Retinal Ganglion Cells Prevents Abnormal Mitochondrial Accumulation and Glaucomatous Neurodegeneration. Molecular Neurodegeneration (2026)

mitochondrial functionneurodegenerative diseasesneuroscienceglaucomaautophagyophthalmology retinaretinaophthalmologymolecular neurodegenerationmolecular medicineganglion cell

Biodistribution of Reconstituted High-Density Lipoprotein Nanoparticles for Targeted Delivery to Retinal Ganglion Cells. Journal of Ocular Pharmacology and Therapeutics (2025)

C/Ebp Homologous Protein Expression in Retinal Ganglion Cells Induces Neurodegeneration in Mice. International Journal of Molecular Sciences (2025)

Genetic and Pharmacological Correction of Impaired Mitophagy in Retinal Ganglion Cells Rescues Glaucomatous Neurodegeneration. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Mechanistic Insights Into Glucocorticoid-Induced Ocular Hypertension Using Differences in Mouse Strain Responsiveness. American Journal Of Pathology (2025)

Therapeutic Mrna Delivery of Crispr-Cas9 to the Trabecular Meshwork Reverses Ocular Hypertension in Myocilin Glaucoma. Molecular Therapy — Methods & Clinical Development (2025)

Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches. Investigative Ophthalmology & Visual Science (2024)

visual scienceocular tissuesintraocular pressure regulationvision researchocular surface physiologyophthalmologyoutflow facilityexperimental ophthalmologyocular surfacemedical optical imaging

Evaluation of Cross-Linked Actin Networks (Clans) in Human Trabecular Meshwork Cells and Tissues. Methods in molecular biology (2024)

Pinkal D PatelAbbot F Clark

tissue engineeringnetwork analysisbiomedical imagingresearch designtrabecular meshworkcross-linked actin networkshuman tissuescell biologyneurosciencebiomedical engineeringtissue (biology)

Lentiviral Mediated Delivery of Crispr/Cas9 Reduces Intraocular Pressure in a Mouse Model of Myocilin Glaucoma. Scientific Reports (2024)

geneticscrisprglaucomapharmacologymyocilin glaucomaophthalmologymouse model

1
2
3
4
5
35
10 / page