Faculty

Institution

Unit

Venue

Charlie Fehl

Assistant Professor

Wayne State University

Affiliations

College of Liberal Arts and Sciences

Chemistry

Graduate School

Charlie Fehl is currently serving as a Chemistry Assistant Professor at Wayne State University.

Honors

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Experiences

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Education

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Charlie Fehl

Wayne State University

Assistant Professor

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glycobiology biochemistry biomolecular engineering molecular biology biological engineering glycosylation catalysis protein science cancer biology organic synthesis cancer research biological chemistry molecular metabolism carbohydrate-protein interactions chemical biology organic chemistry photocatalysis oncology cancer cells medicinal research biomolecules molecular cancer biomolecular interactions cancer genomics catalytic synthesis biocatalysis cellular biochemistry cellulose cell research stem cell research cancer care vascular biology gynecologic oncology chemical sciences laboratory investigation surface chemistry organic material chemistry signaling pathways breast oncology cellular biology cancer growth organometallic catalysis heterogeneous catalysis cell regulation mechanistic photochemistry photoredox process synthetic photochemistry muscle function skeletal muscle small molecule library molecular design catalyst preparation molecular catalysis enzyme catalysis tumor targeting crystal structures interactomics cell interactions pathway analysis metabolic health light-driven post-translational installation glycosyltransferase activity prediction haouamine alkaloids formal synthesis indeno-tetrahydropyridine core cellular roles structure-based design photocatalytic surface patterning visible light diazonium salts triple-negative breast cancer o-glcnac transferase activity cancer stem temperature dependence biological applications complex synthetic metalloclusters

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Scalable Design for Proximity-Inducing Molecules. bioRxiv (Cold Spring Harbor Laboratory) (2026)

synthetic biologybiophysicssmall molecule librarymolecular designlaboratory investigationbiomolecules

O-Glcnacylation Regulates Ppar-Driven Metabolic Programming in Intestinal Stem Cells. bioRxiv (Cold Spring Harbor Laboratory) (2026)

gene expressioncell metabolismmolecular metabolismbiochemistrymetabolic pathwayscell biologymetabolic remodelingmetabolism

Robust Rapid Cellular Metabolite Sensing Using Benchtop Nmr and Sabre-Hyperpolarized [1- 13 C]Pyruvate. Analytical Chemistry (2026)

nuclear magnetic resonance spectroscopycell metabolismbiochemistryanalytical chemistrynuclear magnetic resonance

Abstract B061: Sialylation-Driven Mdsc Generation Shapes the Ovarian Tumor Immune Microenvironment. Cancer Immunology Research (2025)

cancer biologytumor targetingmolecular cancercancer cellstumor microenvironmentabstract b061cancer discoveryradiation oncologyovarian cancersialylation-driven mdsc generationsystems biologytumor biologycell biology

A Reference Dataset of O-Glcnac Proteins in Quadriceps Skeletal Muscle From Mice. Glycobiology (2025)

glycosylationskeletal musclemuscular dystrophiesprotein structuremolecular metabolismmolecular biologyglycobiologymuscle functionphysiology

Thioglycoside Functionalization via Chemoselective Phosphine Acceleration of a Photocatalytic Thiol–Ene Reaction. Chemical Communications (2025)

mechanistic photochemistryphotocatalysiscatalysissynthetic photochemistrychemical sciencesphotochemistryphotoredox processchemical synthesischemistry

Adipose Microenvironment Promotes Hypersialylation of Ovarian Cancer Cells. Frontiers in Oncology (2024)

Alexandra FoxGarry D. LeonardNicholas AdzibolosuTerrence WongRoslyn TedjaSapna SharmaRadhika GogoiRobert MorrisGil MorCharlie FehlAyesha B. Alvero

geneticscancer biologyadipose microenvironmenthealth sciencesgene expressioncancer researchtumor microenvironmentoncologyovarian cancerovarian cancer cellscell regulationimmunologyvascular biologygynecologic oncology

Glycoid Proximity Labeling to Identify O‐Glcnacylated Protein Interactomes in Live Cells. Current Protocols (2024)

Zachary M. NelsonOseni KadiriCharlie Fehl

interactomicsmembrane biologygenomicslive cellsproteomicscarbohydrate-protein interactionsmolecular biologycellular physiologysystems biologyglycobiologygenome biologycell interactionsbiomolecular interactionscell biologymolecular and cellular biologypathway analysisprotein scienceo-glcnacylated protein interactomes

Hyperglycemia and O-Glcnac Transferase Activity Drive a Cancer Stem Cell Pathway in Triple-Negative Breast Cancer. Cancer Cell International (2023)

Saheed A. AyodejiBin BaoEmily A. TeslowLisa A. PolinGreg DysonAliccia Bollig-FischerCharlie Fehl

cancer cellscell biologystem cellscancer biologytriple-negative breast cancercancer researchcancer genomicstumor biologycell researchbreast cancerbreast oncologycancer stemoncologyimmunologystem cell researcho-glcnac transferase activitycancer carecellular biologyradiation oncologymedicinal researchcancer growth

Photocaged Tools to Study O-Glcnac Proteins. Wayne State University Chemistry (2023)

glycosylationbiomolecular structurecarbohydrate chemistrybiological chemistrycarbohydrate-protein interactionsprotein structurebiochemistrystructural molecular biologybiological macromoleculesphotochemistryglycobiologyprotein science

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Charlie Fehl

Assistant Professor

Wayne State University

Affiliations

College of Liberal Arts and Sciences

Chemistry

Graduate School

Charlie Fehl is currently serving as a Chemistry Assistant Professor at Wayne State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Charlie Fehl

Wayne State University

Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Scalable Design for Proximity-Inducing Molecules. bioRxiv (Cold Spring Harbor Laboratory) (2026)

synthetic biologybiophysicssmall molecule librarymolecular designlaboratory investigationbiomolecules

O-Glcnacylation Regulates Ppar-Driven Metabolic Programming in Intestinal Stem Cells. bioRxiv (Cold Spring Harbor Laboratory) (2026)

gene expressioncell metabolismmolecular metabolismbiochemistrymetabolic pathwayscell biologymetabolic remodelingmetabolism

Robust Rapid Cellular Metabolite Sensing Using Benchtop Nmr and Sabre-Hyperpolarized [1- 13 C]Pyruvate. Analytical Chemistry (2026)

nuclear magnetic resonance spectroscopycell metabolismbiochemistryanalytical chemistrynuclear magnetic resonance

Abstract B061: Sialylation-Driven Mdsc Generation Shapes the Ovarian Tumor Immune Microenvironment. Cancer Immunology Research (2025)

A Reference Dataset of O-Glcnac Proteins in Quadriceps Skeletal Muscle From Mice. Glycobiology (2025)

glycosylationskeletal musclemuscular dystrophiesprotein structuremolecular metabolismmolecular biologyglycobiologymuscle functionphysiology

Thioglycoside Functionalization via Chemoselective Phosphine Acceleration of a Photocatalytic Thiol–Ene Reaction. Chemical Communications (2025)

mechanistic photochemistryphotocatalysiscatalysissynthetic photochemistrychemical sciencesphotochemistryphotoredox processchemical synthesischemistry

Adipose Microenvironment Promotes Hypersialylation of Ovarian Cancer Cells. Frontiers in Oncology (2024)

Alexandra FoxGarry D. LeonardNicholas AdzibolosuTerrence WongRoslyn TedjaSapna SharmaRadhika GogoiRobert MorrisGil MorCharlie FehlAyesha B. Alvero

Glycoid Proximity Labeling to Identify O‐Glcnacylated Protein Interactomes in Live Cells. Current Protocols (2024)

Zachary M. NelsonOseni KadiriCharlie Fehl

Hyperglycemia and O-Glcnac Transferase Activity Drive a Cancer Stem Cell Pathway in Triple-Negative Breast Cancer. Cancer Cell International (2023)

Saheed A. AyodejiBin BaoEmily A. TeslowLisa A. PolinGreg DysonAliccia Bollig-FischerCharlie Fehl

Photocaged Tools to Study O-Glcnac Proteins. Wayne State University Chemistry (2023)

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molecular biology

cell biology

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University of Southern California

glycosylation

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Lara K. Mahal

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New York University

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