Faculty

Institution

Unit

Venue

Carston R. Wagner

University of Minnesota Duluth

Affiliations

Medical School

School Of Office Of Research, Medical

NoneCarston R. Wagner is currently serving as a Medical School faculty at University of Minnesota Duluth.

Honors

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Experiences

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Education

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Carston R. Wagner

University of Minnesota Duluth

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pharmacology medicine medicinal chemistry drug discovery pharmacotherapy medicinal research clinical chemistry pharmaceutical chemistry cancer research enzyme inhibition immunology drug delivery chemical synthesis cancer biology tumor targeting cancer treatment biochemistry tumor biology clinical research oncology cellular therapy drug targeting drug development clinical pharmacology pharmacological research brain tumor research clinical investigation protein science cancer care antiviral therapy pharmaceutical research drug targets pharmaceutical sciences molecular pharming oncogenic agent cancer genomics intracellular metabolism oncogenic cap-mediated translation potential inhibitors oncogenes nanoparticle research drug analysis clinical biochemistry pharmaceutics leukemia viral oncology clinical therapeutics antiviral drugs antiviral drug development translational pharmacology molecular docking nanobiotechnology pharmaceutical nanotechnology anti-cancer agents therapeutic nanomaterials rational drug design pharmacokinetics cell regulation lymphoid neoplasia radiopharmaceutical therapy radiation therapy membrane permeation enzyme catalysis anticancer nucleotides thein vivo delivery anticancer drug target antiviral potency non-toxic inhibitors mechanical allodynia opioid antinociception epithelial mesenchymal transition chemical antagonist amino acid phosphoramidates nucleoside monophosphate delivery stable isotope labeling direct measurement

Notable Scholarly Works

Notable Federal Grants

Collaborators

Hint1 Inhibitors as Selective Modulators of Mor–Nmdar Cross-Regulation and Non-Opioid Analgesia. ACS Chemical Neuroscience (2025)

Maxwell DillenburgCristina D. PetersonRafal DolotKostana LigoriKelley F. KittoGeorge L. WilcoxCarolyn A. FairbanksCarston R. Wagner

pharmacologymor-nmdar cross-regulationneurochemistryselective modulatorstherapeutic targetsneuropharmacologyanesthesiologynon-opioid analgesianeuroscience

Multivalent, Bispecific αB7-H3-αCd3 Chemically Self-Assembled Nanorings Direct Potent T Cell Responses Against Medulloblastoma. ACS Nano (2022)

Ellie A. MewsPauline BeckmannMahathi PatchavaYiao WangDavid A. LargaespadaCarston R. Wagner

immunologynanobiotechnologymedicineenzyme inhibitionpharmacologynanomedicinetumor targetingpharmaceutical nanotechnologybrain tumor researchnanoparticle researchpharmacotherapycancer immunotherapycellular therapyanti-cancer agentsnanoparticlesnanomaterialstherapeutic nanomaterialsnanotechnology

4Ei-10 Interdiction of Oncogenic Cap-Mediated Translation as Therapy for Non-Small Cell Lung Cancer. Investigational New Drugs (2020)

Blake A. JacobsonZeeshan AhmadSierra ChenGabriella WalduskyMaxwell DillenburgEmilia StoianDaniel A. CambronAnil J. PatelManish R. PatelCarston R. WagnerRobert A. Kratzke

oncogenic agentdrug developmentmedicinecancer carecancer genomicscancer biologycancer researchcancer treatmentlung canceroncogenic cap-mediated translationpharmacologythoracic oncologyradiation oncologydrug discoveryoncologyclinical researchmedicinal researchclinical investigationexperimental medicine

Anti-Egfr Fibronectin Bispecific Chemically Self-Assembling Nanorings (Csans) Induce Potent T Cell-Mediated Antitumor Responses and Downregulation of Egfr Signaling and Pd-1/Pd-L1 Expression. Journal of Medicinal Chemistry (2020)

Ozgun KilicMarcos R. Matos de SouzaAbdulaziz A. AlmotlakYiao WangJill M. SiegfriedMark D. DistefanoCarston R. Wagner

nanomedicineself-assembling nanoringscell signalingclinical pharmacologyanti-egfr fibronectin bispecifictranslational medicinetumor targetingmedicinecancer researchdrug targetingcancer treatmentcell regulationpharmacological researchimmunologyenzyme inhibitionpharmacologypharmacotherapydrug discoverymedicinal researchcellular therapy

A Phosphoramidate Strategy Enables Membrane Permeability of a Non-Nucleotide Inhibitor of the Prolyl Isomerase Pin1. ACS Medicinal Chemistry Letters (2020)

Daniel M. C. SchwarzSarah K. WilliamsMaxwell DillenburgCarston R. WagnerJason E. Gestwicki

medicinal chemistrynon-nucleotide inhibitorpharmaceutical chemistrymembrane permeationenzyme catalysismembrane permeabilitypharmaceutical sciencesphosphoramidate strategybiochemistrymedicineclinical chemistryenzymesprotein scienceenzyme specificitytherapeutic targetsprotein engineeringenzyme inhibitionpharmacologyredox biologydrug discovery

In Vitro and in Vivo Characterization of the Anti-Zika Virus Activity of Protides of 2′-C-β-Methylguanosine. ACS Infectious Diseases (2020)

Marcos Romário Matos de SouzaMarcela Sabino CunhaAniekan OkonFábio Luís Lima MonteiroLoraine CampanatiCarston R. WagnerLuciana Jesus da Costa

virus researchmedicinedisease transmissionpharmacologyinfection controlviral diagnosticsviral pathogenesisvirologyanti-zika virus activityinfectious diseasesarbovirusemerging infectious diseases

Repression of Oncogenic Cap-Mediated Translation by 4Ei-10 Diminishes Proliferation, Enhances Chemosensitivity and Alters Expression of Malignancy-Related Proteins in Mesothelioma. Cancer Chemotherapy and Pharmacology (2020)

Zeeshan AhmadBlake A. JacobsonMitchell W. McDonaldNicolas Vattendahl VidalGabriel Vattendahl VidalSierra ChenMaxwell DillenburgAniekan M. OkonManish R. PatelCarston R. WagnerRobert A. Kratzke

cancer geneticstumor targetingmedicinecancer caremolecular canceralters expressioncancer biologymalignancy-related proteinscancer researchcancer growthcancer treatmenttumor biologycarcinogenesisoncogenic cap-mediated translationpharmacologypharmacotherapymesotheliomamolecular biologyoncologymedicinal researchcellular therapy

Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of Hhint1. ACS Medicinal Chemistry Letters (2016)

Rachit ShahAlexander StromAndrew ZhouKimberly M. MaizeBarry C. FinzelCarston R. Wagner

medicinal chemistrymedicinepharmaceutical chemistrypharmacologyrational drug designclinical chemistrydrug analysisdrug discoverychemical synthesis

Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is Blocked by a Chemical Antagonist of Translation Factor Eif4e. Scientific Reports (2015)

K. A. SmithB. ZhouS. AvdulovA. BenyumovM. PetersonY. LiuA. OkonP. HergertJ. BraziunasC. R. WagnerZ. BorokP. B. Bitterman

pharmacologyepithelial mesenchymal transitiontumor biologyhealth scienceschemical antagonist

Hint1 Protein: A New Therapeutic Target to Enhance Opioid Antinociception and Block Mechanical Allodynia. Neuropharmacology (2014)

Javier GarzónRaquel Herrero-LabradorMaría Rodríguez-MuñozRachit ShahAna Vicente-SánchezCarston R. WagnerPilar Sánchez-Blázquez

neurologymedicinepharmacologypharmacotherapytherapeutic targetsneuropharmacologymechanical allodyniadrug discoveryopioid antinociceptiondrug targets

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Carston R. Wagner

University of Minnesota Duluth

Affiliations

Medical School

School Of Office Of Research, Medical

NoneCarston R. Wagner is currently serving as a Medical School faculty at University of Minnesota Duluth.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Carston R. Wagner

University of Minnesota Duluth

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Hint1 Inhibitors as Selective Modulators of Mor–Nmdar Cross-Regulation and Non-Opioid Analgesia. ACS Chemical Neuroscience (2025)

Maxwell DillenburgCristina D. PetersonRafal DolotKostana LigoriKelley F. KittoGeorge L. WilcoxCarolyn A. FairbanksCarston R. Wagner

pharmacologymor-nmdar cross-regulationneurochemistryselective modulatorstherapeutic targetsneuropharmacologyanesthesiologynon-opioid analgesianeuroscience

Multivalent, Bispecific αB7-H3-αCd3 Chemically Self-Assembled Nanorings Direct Potent T Cell Responses Against Medulloblastoma. ACS Nano (2022)

Ellie A. MewsPauline BeckmannMahathi PatchavaYiao WangDavid A. LargaespadaCarston R. Wagner

4Ei-10 Interdiction of Oncogenic Cap-Mediated Translation as Therapy for Non-Small Cell Lung Cancer. Investigational New Drugs (2020)

Blake A. JacobsonZeeshan AhmadSierra ChenGabriella WalduskyMaxwell DillenburgEmilia StoianDaniel A. CambronAnil J. PatelManish R. PatelCarston R. WagnerRobert A. Kratzke

Ozgun KilicMarcos R. Matos de SouzaAbdulaziz A. AlmotlakYiao WangJill M. SiegfriedMark D. DistefanoCarston R. Wagner

A Phosphoramidate Strategy Enables Membrane Permeability of a Non-Nucleotide Inhibitor of the Prolyl Isomerase Pin1. ACS Medicinal Chemistry Letters (2020)

Daniel M. C. SchwarzSarah K. WilliamsMaxwell DillenburgCarston R. WagnerJason E. Gestwicki

In Vitro and in Vivo Characterization of the Anti-Zika Virus Activity of Protides of 2′-C-β-Methylguanosine. ACS Infectious Diseases (2020)

Marcos Romário Matos de SouzaMarcela Sabino CunhaAniekan OkonFábio Luís Lima MonteiroLoraine CampanatiCarston R. WagnerLuciana Jesus da Costa

virus researchmedicinedisease transmissionpharmacologyinfection controlviral diagnosticsviral pathogenesisvirologyanti-zika virus activityinfectious diseasesarbovirusemerging infectious diseases

Zeeshan AhmadBlake A. JacobsonMitchell W. McDonaldNicolas Vattendahl VidalGabriel Vattendahl VidalSierra ChenMaxwell DillenburgAniekan M. OkonManish R. PatelCarston R. WagnerRobert A. Kratzke

Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of Hhint1. ACS Medicinal Chemistry Letters (2016)

Rachit ShahAlexander StromAndrew ZhouKimberly M. MaizeBarry C. FinzelCarston R. Wagner

medicinal chemistrymedicinepharmaceutical chemistrypharmacologyrational drug designclinical chemistrydrug analysisdrug discoverychemical synthesis

Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is Blocked by a Chemical Antagonist of Translation Factor Eif4e. Scientific Reports (2015)

K. A. SmithB. ZhouS. AvdulovA. BenyumovM. PetersonY. LiuA. OkonP. HergertJ. BraziunasC. R. WagnerZ. BorokP. B. Bitterman

pharmacologyepithelial mesenchymal transitiontumor biologyhealth scienceschemical antagonist

Hint1 Protein: A New Therapeutic Target to Enhance Opioid Antinociception and Block Mechanical Allodynia. Neuropharmacology (2014)

Javier GarzónRaquel Herrero-LabradorMaría Rodríguez-MuñozRachit ShahAna Vicente-SánchezCarston R. WagnerPilar Sánchez-Blázquez

neurologymedicinepharmacologypharmacotherapytherapeutic targetsneuropharmacologymechanical allodyniadrug discoveryopioid antinociceptiondrug targets

1
2
3
10 / page