Caroline Trumpff

Caroline Trumpff is an Assistant Professor of Medical Psychology (in Psychiatry) at the Columbia University Medical Center. Her research integrates neuroscience, psychoneuroendocrinology, and mitochondrial biology to investigate how psychological stress and daily emotions shape cellular physiology. She has pioneered the use of saliva cell-free mitochondrial DNA (cf-mtDNA) as a dynamic, non-invasive biomarker of stress, and her recent work introduces "Mitotyping," an integrative framework for quantifying mitochondrial specialization and plasticity. Her latest publications also explore mitochondrial energetics, reactive oxygen species production, and calcium handling across the adult lifespan, alongside studies on the mitochondrial disease biomarker GDF15 and its correlation with symptom severity. Her work bridges psychiatry and genetics, with implications for aging and mitochondrial disease research.