Faculty

Institution

Unit

Venue

Carol L. Williams, PhD

Joan K Van Deuren Professor in Breast Cancer Research; Leader Cancer Biology Research Program Cancer Center; Professor Pharmacology & Toxicology

Medical College of Wisconsin

Affiliations

Biochemistry Department

Departments of Pharmacology and Toxicology

Carol L. Williams, Phd is currently serving as a Biochemistry Joan K Van Deuren Professor in Breast Cancer Research; Leader Cancer Biology Research Program Cancer Center; Professor Pharmacology & Toxicology at Medical College of Wisconsin.

Honors

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Experiences

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Education

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Carol L. Williams, PhD

Medical College of Wisconsin

Joan K Van Deuren Professor in Breast Cancer Research; Leader Cancer Biology Research Program Cancer Center; Professor Pharmacology & Toxicology

You can click a keyword to filter the displayed items

pharmacology cell biology tumor biology oncology cancer biology molecular biology cancer research medicinal research cell signaling membrane biology receptors cancer cells lung cancer gene expression thoracic oncology protein science molecular cancer oncogenes medicine cell regulation receptor (biochemistry) cancer genetics molecular cell biology tumor targeting biological chemistry enzyme inhibition redox biology cancer treatment cancer genomics cancer care cellular physiology vascular biology breast oncology cell death molecular regulation cellular therapy anti-cancer agents schistosomiasis cell proliferation cell adhesion veterinary parasitology clinical immunology autoantibody production cellular biology signaling pathways oncogenic agent locomotor activity muscarinic acetylcholine receptors myasthenia gravis cancer management clinical medicine host-parasite relationships cell trafficking apoptosis protein phosphorylation cell migration pancreatic cancer functional modification biomedical research plasma membrane localization small gtpases arginase-dependent pathways inducible nitric oxide reactive oxygen species genitourinary cancers rna biology catalyst activation dna synthesis breast cancer cells altered heartbeat rate cercarial emergence heartbeat rate protein interactions polybasic region alpha actinin protein degradation cardiovascular disease cardiovascular research cardiovascular translational research signal transduction systems biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

An Alkyne-Containing Isoprenoid Analogue Based on a Farnesyl Diphosphate Scaffold is a Biologically Functional Universal Probe for Proteomic Analysis. Biochemistry (2024)

Shelby A. AugerJodi S. PedersenSanjay MaityAndrea M. Sprague-GetsyEllen L. LorimerOlivia J. KoehnSteven A. KrauklisBrenna BernsKatherine M. MurphyJamal HussainPa ThaoKaitlyn BernhagenKatarzyna JustynaAnjana P. SundaresanDaniel B. McKimCarol L. WilliamsJames L. HouglandLing LiMark D. Distefano

pharmaceutical chemistryalkyne-containing isoprenoid analoguemass spectrometrybiochemistryproteomicsfunctional universal probeproteome researchtranslational proteomicsprotein sciencemembrane biologychemical probesbioanalysispeptide sciencefarnesyl diphosphate scaffoldfunctional modificationsynthetic biologytransition metal chemistrybiomolecular analysisnanoparticle researchbiomolecular engineeringmolecular biologyproteomic analysis

Data From Statin-Induced Breast Cancer Cell Death: Role of Inducible Nitric Oxide and Arginase-Dependent Pathways. (2023)

Srigiridhar KotamrajuCarol L. WillamsBalaraman Kalyanaraman

cell deathinducible nitric oxidebreast cancerarginase-dependent pathways

Data From the Smggds Splice Variant Smggds-558 is a Key Promoter of Tumor Growth and Rhoa Signaling in Breast Cancer. (2023)

Andrew D. HauserCarmen BergomNathan J. SchuldXiuxu ChenEllen L. LorimerJian HuangAlexander C. MackinnonCarol L. Williams

metastasissplicing variantcancer riskbreast oncologytumor targetingmolecular cancerbreast cancerleukemiacancer researchcancer growthkey promotertumor biologytumor growthpharmacologyradiation oncologycancer imagingmolecular biologyoncologymedicinal researchcancer cells

Gtpase Splice Variants Rac1 and Rac1B Display Isoform-Specific Differences in Localization, Prenylation, and Interaction With the Chaperone Protein Smggds. Journal of Biological Chemistry (2023)

Olivia J. KoehnEllen LorimerBethany UngerRa’Mal HarrisAkansha S. DasKiall F. SuazoShelby A. AugerMark D. DistefanoJeremy W. ProkopCarol L. Williams

protein structurechaperone protein smggdsbiological chemistrycell and molecular biologybiochemistryenzymesstructural biologybiochemical sciencesprotein scienceprotein secretionbiochemical geneticstranscription (biology)protein misfoldingcellular biochemistryprotein evolutiongeneticshost specificitymolecular biologystructural molecular biology

Novel Regulatory Roles of Small G Protein Gdp Dissociation Stimulator (Smggds) in Insulin Secretion From Pancreatic β-Cells. Molecular and Cellular Endocrinology (2023)

Noah GleasonCarol L. WilliamsAnjaneyulu Kowluru

protein functioncell signalinginsulin secretioncell and molecular biologyliver physiologycell biologyendocrinologymolecular cell biologycomparative endocrinologyprotein sciencemembrane biologyprotein secretioncellular physiologymolecular and cellular biologygdp dissociation stimulatormolecular physiologyendocrine researchphysiologyrenal functiongeneticspancreatic b-cellsnovel regulatory roles

Supplementary Figures 1-3 From Statin-Induced Breast Cancer Cell Death: Role of Inducible Nitric Oxide and Arginase-Dependent Pathways. (2023)

Srigiridhar KotamrajuCarol L. WillamsBalaraman Kalyanaraman

cell deathinducible nitric oxidebreast cancerarginase-dependent pathways

Synthesis, Enzymatic Peptide Incorporation, and Applications of Diazirine-Containing Isoprenoid Diphosphate Analogues. Organic Letters (2023)

Katarzyna JustynaRiki DasEllen L. LorimerJiayue HuJodi S. PedersenAndrea M. Sprague-GetsyGarrett L. ScheyMichelle A. SieburgOlivia J. KoehnYen-Chih WangYong-Xiang ChenJames L. HouglandCarol L. WilliamsMark D. Distefano

medicinal chemistryorganic chemistrychemical engineeringorganic synthesisbiomolecular engineeringenzymatic peptide incorporationsynthetic biologysynthetic chemistrychemical synthesisbiological engineeringpeptide synthesis

Rap1A, Rap1B, and β-Adrenergic Signaling in Autologous Hct: A Randomized Controlled Trial of Propranolol.. PubMed (2022)

Alexander K JohnsonEllen L LorimerAniko SzaboRuizhe WuNirav N ShahAnita D'SouzaSaurabh ChhabraMehdi HamadaniBinod DhakalParameswaran HariSridhar RaoKaren CarlsonCarol L WilliamsJennifer M Knight

medicinepharmacologyb-adrenergic signalingcell signalingclinical trialsautologous hctoncologyhepatologymedicinal researchsignal transductionhealth sciences

Structural and Biophysical Properties of Farnesylated Kras Interacting With the Chaperone Smggds-558. Biophysical Journal (2022)

Dennis J. MichalakBethany UngerEllen LorimerAlexander GrishaevCarol L. WilliamsFrank HeinrichMathias Lösche

structural biologybiophysicsprotein structurefarnesylated kras

The Complex, Dynamic Spliceome of the Small Gtpase Transcripts Altered by Technique, Sex, Genetics, Tissue Specificity, and Rna Base Editing. Frontiers in Cell and Developmental Biology (2022)

Akansha S. DasEmily C. SherryRobert M. VaughanMarian L. HendersonJacob ZiebaKatie L. UhlOlivia KoehnCaleb P. BuppSurender RajasekaranXiaopeng LiSurya B. ChhetriSahar NissimCarol L. WilliamsJeremy W. Prokop

gene editingepigenetic changestissue specificitycell and molecular biologygenome biologymolecular cell biologysmall gtpase transcriptsgenetic engineeringcellular biologynucleic acidsrna base editingdynamic spliceomeepigenomicstranscription (biology)developmental biologydevelopmental sciencecellular biochemistrygenomicsgeneticsdevelopmental geneticsmolecular biologymolecular genetics

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Carol L. Williams, PhD

Joan K Van Deuren Professor in Breast Cancer Research; Leader Cancer Biology Research Program Cancer Center; Professor Pharmacology & Toxicology

Medical College of Wisconsin

Affiliations

Biochemistry Department

Departments of Pharmacology and Toxicology

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Carol L. Williams, PhD

Medical College of Wisconsin

Joan K Van Deuren Professor in Breast Cancer Research; Leader Cancer Biology Research Program Cancer Center; Professor Pharmacology & Toxicology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

An Alkyne-Containing Isoprenoid Analogue Based on a Farnesyl Diphosphate Scaffold is a Biologically Functional Universal Probe for Proteomic Analysis. Biochemistry (2024)

Data From Statin-Induced Breast Cancer Cell Death: Role of Inducible Nitric Oxide and Arginase-Dependent Pathways. (2023)

Srigiridhar KotamrajuCarol L. WillamsBalaraman Kalyanaraman

cell deathinducible nitric oxidebreast cancerarginase-dependent pathways

Data From the Smggds Splice Variant Smggds-558 is a Key Promoter of Tumor Growth and Rhoa Signaling in Breast Cancer. (2023)

Andrew D. HauserCarmen BergomNathan J. SchuldXiuxu ChenEllen L. LorimerJian HuangAlexander C. MackinnonCarol L. Williams

Gtpase Splice Variants Rac1 and Rac1B Display Isoform-Specific Differences in Localization, Prenylation, and Interaction With the Chaperone Protein Smggds. Journal of Biological Chemistry (2023)

Olivia J. KoehnEllen LorimerBethany UngerRa’Mal HarrisAkansha S. DasKiall F. SuazoShelby A. AugerMark D. DistefanoJeremy W. ProkopCarol L. Williams

Novel Regulatory Roles of Small G Protein Gdp Dissociation Stimulator (Smggds) in Insulin Secretion From Pancreatic β-Cells. Molecular and Cellular Endocrinology (2023)

Noah GleasonCarol L. WilliamsAnjaneyulu Kowluru

Supplementary Figures 1-3 From Statin-Induced Breast Cancer Cell Death: Role of Inducible Nitric Oxide and Arginase-Dependent Pathways. (2023)

Srigiridhar KotamrajuCarol L. WillamsBalaraman Kalyanaraman

cell deathinducible nitric oxidebreast cancerarginase-dependent pathways

Synthesis, Enzymatic Peptide Incorporation, and Applications of Diazirine-Containing Isoprenoid Diphosphate Analogues. Organic Letters (2023)

Rap1A, Rap1B, and β-Adrenergic Signaling in Autologous Hct: A Randomized Controlled Trial of Propranolol.. PubMed (2022)

Alexander K JohnsonEllen L LorimerAniko SzaboRuizhe WuNirav N ShahAnita D'SouzaSaurabh ChhabraMehdi HamadaniBinod DhakalParameswaran HariSridhar RaoKaren CarlsonCarol L WilliamsJennifer M Knight

medicinepharmacologyb-adrenergic signalingcell signalingclinical trialsautologous hctoncologyhepatologymedicinal researchsignal transductionhealth sciences

Structural and Biophysical Properties of Farnesylated Kras Interacting With the Chaperone Smggds-558. Biophysical Journal (2022)

Dennis J. MichalakBethany UngerEllen LorimerAlexander GrishaevCarol L. WilliamsFrank HeinrichMathias Lösche

structural biologybiophysicsprotein structurefarnesylated kras

The Complex, Dynamic Spliceome of the Small Gtpase Transcripts Altered by Technique, Sex, Genetics, Tissue Specificity, and Rna Base Editing. Frontiers in Cell and Developmental Biology (2022)

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