Faculty

Institution

Unit

Venue

Carlo Manno

Rush University

Affiliations

Department Of Molecular Biophysics And Physiology

News & Events

Rush University

NoneCarlo Manno is currently serving as a Molecular Biophysics And Physiology faculty at Rush University.

Honors

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Experiences

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Education

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Carlo Manno

Rush University

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physiology skeletal muscle cellular physiology muscle function electrophysiology molecular physiology muscular dystrophies neuroscience cell biology cell physiology neurophysiology signal transduction mechanobiology applied physiology cell metabolism hyperthermia neuromuscular medicine neurons musculoskeletal disorders protein science malignant hyperthermia pharmacology cardiology diabetes research molecular neurodegeneration mitochondrial function sarcoplasmic reticulum cardiac muscle neuromusculoskeletal disorders human physiology physiological research neurotransmission mechanotransduction diabetes mellitus tissue imaging parathyroid hormone protein secretion calcium store mouse skeletal muscle animal physiology liver physiology diabetes therapies diabetic medicine mammalian biology membrane science biomedical circuits molecular cell biology human sciences mitochondrial dynamics insulin signaling microvascular dysfunction translational physiology mammalian physiology disease physiology clinical physiology membrane transport hyperpolarization (biology) metabolic regulation metabolic complications bioimage analysis medical image analysis human tissues mineral metabolism sarcopenia paradoxical buffering electrical stimulation action potentials comparative approach human muscle calcium transients mouse model dynamic measurement abnormal calcium signalling confocal imaging excitation-contraction coupling voltage sensor

Notable Scholarly Works

Notable Federal Grants

Collaborators

Calpain Mediated Proteolysis of Junctophilin-1 Produces an Aggregation Prone C-Terminal Fragment in Skeletal Muscle. Research Square (2026)

cell physiologycalpain mediated proteolysisjunctophilin-1 producesphysiologyprotein sciencemuscle functioncell biologycellular physiologyprotein functionbiochemistrymolecular physiologycytoskeletonmolecular motorsmechanobiologyskeletal musclesignal transductioncellular biochemistry

Age‐Dependent Effects of Muscle Resting Calcium on Fasting Blood Glucose: Implications for Prediabetes Risk. Endocrinology Diabetes & Metabolism (2025)

metabolic syndromemetabolismdiabetic neuropathydiabetes mellitusmuscle resting calciumphysiologyfasting blood glucosediabetes researchsarcopeniaage‐dependent effectshealth sciencesdiabetes

Disrupting the Feed-Forward Cycle of Ryr1 Ca 2+ Leak and Oxidative Stress Mitigates Doxorubicin-Induced Skeletal Myopathy. bioRxiv (Cold Spring Harbor Laboratory) (2025)

cell physiologymyositisphysiologymuscle functioncell biologycellular physiologybiochemistrycell metabolismmolecular physiologymechanobiologyoxidative stressskeletal musclemuscular dystrophiesfeed-forward cyclesignal transductionmusculoskeletal disorders

Skeletal Muscle Disorders as Risk Factors for Type 2 Diabetes. Molecular and Cellular Endocrinology (2025)

diabetes caremetabolic syndrometype 2chronic diseasesdiabetes mellitusphysiologydiabetes researchskeletal musclemuscular dystrophiesmetabolic complicationsmusculoskeletal disordershealth sciencesdiabetes

Artificial Intelligence Approaches to the Volumetric Quantification of Glycogen Granules in Em Images of Human Tissue. The Journal of General Physiology (2024)

Eduardo RíosMontserrat SamsóLourdes C. FigueroaCarlo MannoEshwar R. TammineniLucas Rios GiordanoSheila Riazi

tissue imagingem imagesphysiologymedical imaginghuman physiologyhuman tissuesmedical image analysisvolumetric quantificationbioimage analysisglycogen granulesimage analysisbiomedical imaging

Deep Learning Convolutional Neural Networks for the Quantification of Glycogen in Electron Micrographs of Calcium-Stressed Human Muscle. Biophysical Journal (2024)

Eduardo RiosMontserrat SamsoEshwar Reddy TammineniLourdes C. FigueroaCarlo D. MannoSheila Riazi

biophysicsmedical biophysicsexercise physiologydeep learningphysiologymuscle functionelectrophysiologycellular physiologyneurosciencetissue physiologyexperimental biophysicsbioenergeticsneurophysiologymembrane biologymolecular physiologycomputational biophysicscalcium-stressed human muscleelectron micrographs

Distinct Pathophysiological Characteristics in Developing Muscle From Patients Susceptible to Malignant Hyperthermia. British Journal of Anaesthesia (2023)

myositisphysiologymuscle functiondistinct pathophysiological characteristicsneuromuscular medicinekinesiologyneuromusculoskeletal disordersmechanobiologyskeletal musclemuscular dystrophieshyperthermiaapplied physiology

Muscle Calcium Stress Cleaves Junctophilin1, Unleashing a Gene Regulatory Program Predicted to Correct Glucose Dysregulation. eLife (2023)

molecular and cellular biologymuscle functionglucose dysregulationcell physiologyphysiologycell signalingcell biologymolecular biologygene expressioncellular physiologycell metabolismskeletal musclemolecular metabolismgene regulatory programmetabolic regulationmetabolic pathwaysmolecular physiologymolecular cell biologysignal transduction

A Novel Method for Determining Murine Skeletal Muscle Fiber Type Using Autofluorescence Lifetimes. The Journal of General Physiology (2022)

biophysicsautofluorescence lifetimesphysiologymuscle functionfibersnovel methodadvanced fiber materialfluorescence spectroscopybiomedical engineeringmechanobiologyskeletal musclemuscular dystrophiesfluorescencetissue (biology)biomechanics

Quantification of the Calcium Signaling Deficit in Muscles Devoid of Triadin. PLoS ONE (2022)

cell physiologyphysiologymuscle functionelectrophysiologycell biologycellular physiologymechanotransductionmuscles devoidmolecular physiologyskeletal musclemuscular dystrophiessignal transductionmusculoskeletal disorderscardiac muscle

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Carlo Manno

Rush University

Affiliations

Department Of Molecular Biophysics And Physiology

News & Events

Rush University

NoneCarlo Manno is currently serving as a Molecular Biophysics And Physiology faculty at Rush University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Carlo Manno

Rush University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Calpain Mediated Proteolysis of Junctophilin-1 Produces an Aggregation Prone C-Terminal Fragment in Skeletal Muscle. Research Square (2026)

Age‐Dependent Effects of Muscle Resting Calcium on Fasting Blood Glucose: Implications for Prediabetes Risk. Endocrinology Diabetes & Metabolism (2025)

metabolic syndromemetabolismdiabetic neuropathydiabetes mellitusmuscle resting calciumphysiologyfasting blood glucosediabetes researchsarcopeniaage‐dependent effectshealth sciencesdiabetes

Disrupting the Feed-Forward Cycle of Ryr1 Ca 2+ Leak and Oxidative Stress Mitigates Doxorubicin-Induced Skeletal Myopathy. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Skeletal Muscle Disorders as Risk Factors for Type 2 Diabetes. Molecular and Cellular Endocrinology (2025)

Artificial Intelligence Approaches to the Volumetric Quantification of Glycogen Granules in Em Images of Human Tissue. The Journal of General Physiology (2024)

Eduardo RíosMontserrat SamsóLourdes C. FigueroaCarlo MannoEshwar R. TammineniLucas Rios GiordanoSheila Riazi

tissue imagingem imagesphysiologymedical imaginghuman physiologyhuman tissuesmedical image analysisvolumetric quantificationbioimage analysisglycogen granulesimage analysisbiomedical imaging

Deep Learning Convolutional Neural Networks for the Quantification of Glycogen in Electron Micrographs of Calcium-Stressed Human Muscle. Biophysical Journal (2024)

Eduardo RiosMontserrat SamsoEshwar Reddy TammineniLourdes C. FigueroaCarlo D. MannoSheila Riazi

Distinct Pathophysiological Characteristics in Developing Muscle From Patients Susceptible to Malignant Hyperthermia. British Journal of Anaesthesia (2023)

Muscle Calcium Stress Cleaves Junctophilin1, Unleashing a Gene Regulatory Program Predicted to Correct Glucose Dysregulation. eLife (2023)

A Novel Method for Determining Murine Skeletal Muscle Fiber Type Using Autofluorescence Lifetimes. The Journal of General Physiology (2022)

Quantification of the Calcium Signaling Deficit in Muscles Devoid of Triadin. PLoS ONE (2022)

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5
10 / page