Byron Lee, MD, PhD

Byron Lee, MD, PhD, is an Associate Professor at The University of Texas MD Anderson Cancer Center. A surgical oncologist specializing in genitourinary malignancies, his research focuses on bladder cancer biology, tumor immunology, and precision oncology. His recent work defines molecular subtypes of bladder cancer through xenograft profiling and single-cell RNA-sequencing, identifying a CD6/ALCAM-mediated immune-suppressive pathway in BCG-naïve and recurrent non-muscle invasive disease. He has also contributed to international consensus recommendations for intermediate-risk non-muscle-invasive bladder cancer and investigated surgical approaches, including partial cystectomy and arterial embolization for renal angiomyolipomas. His translational research bridges molecular mechanisms with clinical applications in urologic oncology.