Faculty

Institution

Unit

Venue

Bryant G. Darnay

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Molecular And Cellular Oncology

NoneBryant G. Darnay is currently serving as a Molecular And Cellular Oncology faculty at The University of Texas Md Anderson Cancer Center.

Honors

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Experiences

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Education

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Bryant G. Darnay

The University of Texas MD Anderson Cancer Center

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cell signaling cell biology molecular biology signal transduction immunology tumor biology medicinal research pharmacology biological chemistry molecular physiology molecular medicine molecular and cellular biology protein science cell death receptors cell and molecular biology membrane biology molecular cell biology cancer cells oncogenes cellular biochemistry molecular cancer enzyme inhibition cellular physiology molecular regulation protein phosphorylation cancer biology bone research cellular therapy cell regulation protein function bone homeostasis signaling pathways receptor (biochemistry) experimental medicine structural molecular biology receptor tyrosine kinases cellular biology anti-cancer agents hematological malignancies cytoplasmic domain gene regulation crystal structures mammalian physiology catalyst activation pharmaceutical chemistry drug targeting molecular substrates surface reactivity molecular basis molecular evidence molecular docking molecular research mixed-phenotype acute leukemia skeletal muscle biomolecular interactions functional modification g protein-coupled receptor bone metabolism bone remodeling rna biology akt ubiquitination ikb kinase activation bone growth multiple functions postnatal mice ikba phosphorylation nf-kb activation potent inhibitor oxygen-independent degradation hypoxia-associated factor unique deubiquitinating activity persistent activation lyn kinase multiple mechanisms functional interaction cancer letter cancer immunotherapy autoimmune diseases leukemia autoimmunity therapeutic targets carcinogenesis metastasis molecular diagnostics sarcoma oncology cancer research immunotherapy systems biology brain tumor research tumor microenvironment cancer discovery clinical proteomics immune responses radiation oncology ovarian cancer transcription factors biochemistry cell research immunity (medicine) rheumatism jama oncology gynecologic oncology molecular gastroenterology inflammation dermatology pathology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Hypoxia-Induced Sumoylation of E3 Ligase Haf Determines Specific Activation of Hif2 in Clear-Cell Renal Cell Carcinoma. (2023)

Mei Yee KohVuvi NguyenRobert LemosBryant G. DarnayGalina KiriakovaMena AbdelmelekThai H. HoJose KaramFederico A. MonzonEric JonaschGarth Powis

cancer biologypharmacologyhypoxia-induced sumoylationurologytumor biologycancer researchoncologymembrane biologyradiation oncologygenitourinary cancersredox biologyheme signalingtumor targetingmedicinal researchcancer imaginghematological malignanciesoncogenesenzyme inhibitionkidney cancer

Data From Inhibition of Prostate Tumor Growth and Bone Remodeling by the Vascular Targeting Agent Vegf Sub 121 /Sub /Rgel. (2023)

A Traf2 Binding Independent Region of Tnfr2 is Responsible for Traf2 Depletion and Enhancement of Cytotoxicity Driven by Tnfr1. Oncotarget (2013)

Bsta Promotes Mtorc2-Mediated Phosphorylation of Akt1 to Suppress Expression of Foxc2 and Stimulate Adipocyte Differentiation. Science Signaling (2013)

Yixin YaoMilind SuraokarBryant G. DarnayBrett G. HollierTattym E. ShaikenTakayuki AsanoChien-Hung ChenBenny H.-J. ChangYiling LuGordon B. MillsDos SarbassovSendurai A. ManiJames L. AbbruzzeseShrikanth A. G. Reddy

tumor biologysignaling pathwaysliver physiologyinsulin signalingadipocyte differentiationcell biologycell signalingredox biologypharmacologymembrane biologyphysiologysignal transductionprotein expressiongene expressiongene functionredox signalingmedicinal researchmolecular physiology

Cycles of Ubiquitination and Deubiquitination Critically Regulate Growth Factor–Mediated Activation of Akt Signaling. Science Signaling (2013)

Wei-Lei YangGuoxiang JinChien-Feng LiYun Seong JeongAsad MotenDazhi XuZizhen FengWei ChenZhen CaiBryant DarnayWei GuHui-Kuan Lin

cell regulationcell signalingneuroscienceimmunologypharmacologysignal transduction

Ubiquitin-Specific Protease 25 Regulates Tlr4-Dependent Innate Immune Responses Through Deubiquitination of the Adaptor Protein Traf3. Science Signaling (2013)

Deletion of Tak1 in the Myeloid Lineage Results in the Spontaneous Development of Myelomonocytic Leukemia in Mice. PLoS ONE (2012)

Betty LamotheYunJu LaiLana HurNatalia Martin OrozcoJing WangAlejandro D. CamposMin XieMichael D. SchneiderCynthia R. LockworthJared JakackyDiep TranMichael HoSity DawudChen DongHui-Kuan LinPeter HuZeev EstrovCarlos E. Bueso-RamosBryant G. Darnay

developmental biologyhematologyepigeneticsgeneticsspontaneous developmentmyelomonocytic leukemiacytogeneticsimmunologymammalian biologygene expressioncancer genetics

Regulation of Tlr-Triggered Innate Immune Response by Ubiquitin-Specific Protease 25 (180.8). The Journal of Immunology (2012)

Tak1 is Essential for Osteoclast Differentiation and is an Important Modulator of Cell Death by Apoptosis and Necroptosis. Molecular and Cellular Biology (2012)

The E3 Ubiquitin Ligase Traf6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy Through Multiple Mechanisms. Molecular and Cellular Biology (2012)

Pradyut K. PaulShephali BhatnagarVivek MishraSanjay SrivastavaBryant G. DarnayYongwon ChoiAshok Kumar

skeletal musclebiomolecular interactionscell biologycell signalingprotein sciencemolecular regulationfunctional modificationmolecular physiologymolecular and cellular biologymolecular biologycell and molecular biologyphysiologymultiple mechanismscell deathstructural biologyexercise physiologystructural molecular biologycellular biologycellular physiology

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Bryant G. Darnay

The University of Texas MD Anderson Cancer Center

Affiliations

Department Of Molecular And Cellular Oncology

NoneBryant G. Darnay is currently serving as a Molecular And Cellular Oncology faculty at The University of Texas Md Anderson Cancer Center.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Bryant G. Darnay

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Hypoxia-Induced Sumoylation of E3 Ligase Haf Determines Specific Activation of Hif2 in Clear-Cell Renal Cell Carcinoma. (2023)

Mei Yee KohVuvi NguyenRobert LemosBryant G. DarnayGalina KiriakovaMena AbdelmelekThai H. HoJose KaramFederico A. MonzonEric JonaschGarth Powis

Data From Inhibition of Prostate Tumor Growth and Bone Remodeling by the Vascular Targeting Agent Vegf Sub 121 /Sub /Rgel. (2023)

A Traf2 Binding Independent Region of Tnfr2 is Responsible for Traf2 Depletion and Enhancement of Cytotoxicity Driven by Tnfr1. Oncotarget (2013)

Bsta Promotes Mtorc2-Mediated Phosphorylation of Akt1 to Suppress Expression of Foxc2 and Stimulate Adipocyte Differentiation. Science Signaling (2013)

Cycles of Ubiquitination and Deubiquitination Critically Regulate Growth Factor–Mediated Activation of Akt Signaling. Science Signaling (2013)

Wei-Lei YangGuoxiang JinChien-Feng LiYun Seong JeongAsad MotenDazhi XuZizhen FengWei ChenZhen CaiBryant DarnayWei GuHui-Kuan Lin

cell regulationcell signalingneuroscienceimmunologypharmacologysignal transduction

Ubiquitin-Specific Protease 25 Regulates Tlr4-Dependent Innate Immune Responses Through Deubiquitination of the Adaptor Protein Traf3. Science Signaling (2013)

Deletion of Tak1 in the Myeloid Lineage Results in the Spontaneous Development of Myelomonocytic Leukemia in Mice. PLoS ONE (2012)

developmental biologyhematologyepigeneticsgeneticsspontaneous developmentmyelomonocytic leukemiacytogeneticsimmunologymammalian biologygene expressioncancer genetics

Regulation of Tlr-Triggered Innate Immune Response by Ubiquitin-Specific Protease 25 (180.8). The Journal of Immunology (2012)

Tak1 is Essential for Osteoclast Differentiation and is an Important Modulator of Cell Death by Apoptosis and Necroptosis. Molecular and Cellular Biology (2012)

The E3 Ubiquitin Ligase Traf6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy Through Multiple Mechanisms. Molecular and Cellular Biology (2012)

Pradyut K. PaulShephali BhatnagarVivek MishraSanjay SrivastavaBryant G. DarnayYongwon ChoiAshok Kumar

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5
6
10 / page