Faculty

Institution

Unit

Venue

Bruce Torbett

University of Washington

Affiliations

School of Medicine

Laboratory Medicine

Pathology

Pediatrics

NoneBruce Torbett is currently serving as a Laboratory Medicine faculty at University of Washington.

Honors

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Experiences

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Education

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Bruce Torbett

University of Washington

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immunology virology genetics hiv hematology gene expression pharmacology cell biology mammalian biology medicinal research virus research general virology virus-host interactions viral genetics gene therapy immune responses membrane biology tumor biology medical virology protein science antiviral therapy cancer biology molecular virology viral evolution clinical microbiology antiviral research viral pathogenesis gene function gene regulation cancer genetics transcription regulation adaptive immune system cell regulation vascular biology leukemia antiviral drug development genome biology liver physiology enzyme inhibition antiviral drugs human retrovirus hematological malignancies cellular immune responses clinical immunology angiogenesis stem cell research infection control structural molecular biology viral structural protein tumor suppressors molecular regulation granulocyte viral diagnostics rna biology animal virus molecular immunology viral replication genome sequencing virus transmission drug targeting progenitor cells neutrophil differentiation hematopoietic stem cells myeloid development nucleocapsid protein apl cells granulocytic differentiation hiv vectors long-term engraftment porcine endogenous retrovirus scid mice islet xenotransplantation erythroid differentiation cytokine gene expression lymphokine secretion aged mice

Notable Scholarly Works

Notable Federal Grants

Collaborators

APHIX: Analysis Pipeline for Hiv-1 Isoform Exploration Using Long-Read Rna Sequencing Data. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jessica L AlbertChristian M GallardoBruce E Torbett

microbiologyhivviral diagnosticsbioinformaticsanalysis pipelinemedical virologygene expressionmolecular diagnosticslong-read sequencingsystems biologyhigh throughput sequencingvirus researchvirologygenomicsmolecular informaticsnext-generation sequencinglong-read rnaantiviral researchsequence analysismolecular biology

Hspa8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation. Pharmacology (2024)

Sreoshee RafiqIrene MungureYara BanzNicolas J NiklausThomas KaufmannStefan MüllerArnaud JacquelGuillaume RobertPatrick AubergerBruce E TorbettSylviane MullerMario P TschanMagali Humbert

medicinecancer biologycell biologyleukemiaautophagypharmacologygene expressionpharmacokineticstumor biologycancer researchcell regulationmedicinal researchcellular differentiationpharmacological researchgene regulationsignal transductionclinical pharmacologypharmacotherapychaperone-mediated autophagy regulation

Identification of Clickable Hiv-1 Capsid-Targeting Probes for Viral Replication Inhibition. Cell chemical biology (2024)

William M. McFaddenMary C. Casey-MooreGrant A.L. BareKaren A. KirbyXin WenGencheng LiHua WangRyan L. SlackAlexa A. SnyderZachary C. LorsonIsabella L. KaufmanMaria E. CilentoPhilip R. TedburyMilan GembickyArthur J. OlsonBruce E. TorbettK. Barry SharplessStefan G. Sarafianos

virologyhivantiviral researchmedical virologyimmunologyviral replicationtherapeutic targetsmolecular biologyhuman retrovirusviral replication inhibitionvirus research

Ip6 and Pf74 Affect Hiv-1 Capsid Stability Through Modulation of Hexamer-Hexamer Tilt Angle Preference. Biophysical Journal (2024)

Chris M GarzaMatthew HolcombDiogo Santos-MartinsBruce E TorbettStefano Forli

virologyhivviral dynamicsimmunologyhealth sciencesgeneral virologyepidemiology

MRHAMER2: High-Accuracy Long-Read Rna Sequencing to Decode Isoform-Specific Variation in Viral Transcripts During Latency. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Christian M. GallardoJessica L. AlbertAndrew A. QaziRoni Lobato VenturaSavitha DeshmukhNadejda Beliakova-BethellBruce E. Torbett

bioinformaticslong-read sequencinghigh-accuracy long-read rnahigh throughput sequencingviral transcriptsmolecular biologyisoform-specific variationnext-generation sequencing

A Lentiviral Vector B Cell Gene Therapy Platform for the Delivery of the Anti-Hiv-1 Ecd4-Ig-Knob-In-Hole-Reversed Immunoadhesin. Molecular Therapy — Methods & Clinical Development (2023)

Eirini VamvaStosh OzogDaniel P. LeamanRene Yu-Hong ChengNicholas J. IronsAndee OttClaire StoffersIram KhanGeraldine K.E. GoebrechtMatthew R. GardnerMichael FarzanDavid J. RawlingsMichael B. ZwickRichard G. JamesBruce E. Torbett

hivvirologymedicineimmunologypharmacologyantiviral therapygene therapyclinical researchtreatment development

Data From Modulation of Drug Resistance by Artificial Transcription Factors. (2023)

Pilar BlancafortMario P. TschanSharon BergquistDaniel GuthyArndt BrachatDennis A. SheeterBruce E. TorbettDirk ErdmannCarlos F. Barbas

bioinformaticsdrug resistancegene regulationartificial transcription factorsbiostatisticsdata sciencepharmacologyrna biologytranscription regulationgene expression

VIREMA: A Virus Recombination Mapper of Next-Generation Sequencing Data Characterizes Diverse Recombinant Viral Nucleic Acids. GigaScience (2023)

Stephanea SotcheffYiyang ZhouJason YeungYan SunJohn E JohnsonBruce E TorbettAndrew L Routh

virologygeneticsbioinformaticsdna sequencinggenomicsvirus recombination mappernext-generation sequencingvirus research

Potent Dual Block to Hiv-1 Infection Using Lentiviral Vectors Expressing Fusion Inhibitor Peptide Mc46- and Vif-Resistant Apobec3g. Molecular Therapy — Nucleic Acids (2023)

Krista A. Delviks-FrankenberryChet R. OjhaKip J. HermannWei-Shau HuBruce E. TorbettVinay K. Pathak

antiviral drug developmenthivmedicinefusion inhibitordrug resistancemedical virologypharmacologygene expressionclinical microbiologyantiviral compoundsantiviral therapyvirologyinfectious diseasespotent dual blockpeptide therapeuticsgene therapymedicinal researchantiviral researchnucleic acidslentiviral vectorsgene vector

Activation of Hiv-1 Proviruses Increases Downstream Chromatin Accessibility. iScience (2022)

Raven ShahChristian M. GallardoYoonhee H. JungBen ClockJesse R. DixonWilliam M. McFaddenKinjal MajumderDavid J. PintelVictor G. CorcesBruce E. TorbettPhilip R. TedburyStefan G. Sarafianos

hivvirologyepigeneticsmolecular virologydownstream chromatin accessibilityviral geneticsinfectious diseasesvirus-host interactionsimmunologyviral pathogenesishuman retrovirushealth sciencesgeneral virologyvirus research

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Bruce Torbett

University of Washington

Affiliations

School of Medicine

Laboratory Medicine

Pathology

Pediatrics

NoneBruce Torbett is currently serving as a Laboratory Medicine faculty at University of Washington.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Bruce Torbett

University of Washington

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

APHIX: Analysis Pipeline for Hiv-1 Isoform Exploration Using Long-Read Rna Sequencing Data. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jessica L AlbertChristian M GallardoBruce E Torbett

Hspa8 Chaperone Complex Drives Chaperone-Mediated Autophagy Regulation in Acute Promyelocytic Leukemia Cell Differentiation. Pharmacology (2024)

Sreoshee RafiqIrene MungureYara BanzNicolas J NiklausThomas KaufmannStefan MüllerArnaud JacquelGuillaume RobertPatrick AubergerBruce E TorbettSylviane MullerMario P TschanMagali Humbert

Identification of Clickable Hiv-1 Capsid-Targeting Probes for Viral Replication Inhibition. Cell chemical biology (2024)

virologyhivantiviral researchmedical virologyimmunologyviral replicationtherapeutic targetsmolecular biologyhuman retrovirusviral replication inhibitionvirus research

Ip6 and Pf74 Affect Hiv-1 Capsid Stability Through Modulation of Hexamer-Hexamer Tilt Angle Preference. Biophysical Journal (2024)

Chris M GarzaMatthew HolcombDiogo Santos-MartinsBruce E TorbettStefano Forli

virologyhivviral dynamicsimmunologyhealth sciencesgeneral virologyepidemiology

MRHAMER2: High-Accuracy Long-Read Rna Sequencing to Decode Isoform-Specific Variation in Viral Transcripts During Latency. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Christian M. GallardoJessica L. AlbertAndrew A. QaziRoni Lobato VenturaSavitha DeshmukhNadejda Beliakova-BethellBruce E. Torbett

bioinformaticslong-read sequencinghigh-accuracy long-read rnahigh throughput sequencingviral transcriptsmolecular biologyisoform-specific variationnext-generation sequencing

A Lentiviral Vector B Cell Gene Therapy Platform for the Delivery of the Anti-Hiv-1 Ecd4-Ig-Knob-In-Hole-Reversed Immunoadhesin. Molecular Therapy — Methods & Clinical Development (2023)

hivvirologymedicineimmunologypharmacologyantiviral therapygene therapyclinical researchtreatment development

Data From Modulation of Drug Resistance by Artificial Transcription Factors. (2023)

Pilar BlancafortMario P. TschanSharon BergquistDaniel GuthyArndt BrachatDennis A. SheeterBruce E. TorbettDirk ErdmannCarlos F. Barbas

bioinformaticsdrug resistancegene regulationartificial transcription factorsbiostatisticsdata sciencepharmacologyrna biologytranscription regulationgene expression

VIREMA: A Virus Recombination Mapper of Next-Generation Sequencing Data Characterizes Diverse Recombinant Viral Nucleic Acids. GigaScience (2023)

Stephanea SotcheffYiyang ZhouJason YeungYan SunJohn E JohnsonBruce E TorbettAndrew L Routh

virologygeneticsbioinformaticsdna sequencinggenomicsvirus recombination mappernext-generation sequencingvirus research

Potent Dual Block to Hiv-1 Infection Using Lentiviral Vectors Expressing Fusion Inhibitor Peptide Mc46- and Vif-Resistant Apobec3g. Molecular Therapy — Nucleic Acids (2023)

Krista A. Delviks-FrankenberryChet R. OjhaKip J. HermannWei-Shau HuBruce E. TorbettVinay K. Pathak

Activation of Hiv-1 Proviruses Increases Downstream Chromatin Accessibility. iScience (2022)

Raven ShahChristian M. GallardoYoonhee H. JungBen ClockJesse R. DixonWilliam M. McFaddenKinjal MajumderDavid J. PintelVictor G. CorcesBruce E. TorbettPhilip R. TedburyStefan G. Sarafianos

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